Elena Verena Winkler, Susanne Katja Lauer, Stephanie Steigmeier-Raith
{"title":"[Kinematic gait analysis in dogs: Is modern gait analysis finding its way into veterinary practice?]","authors":"Elena Verena Winkler, Susanne Katja Lauer, Stephanie Steigmeier-Raith","doi":"10.1055/a-2628-4859","DOIUrl":"10.1055/a-2628-4859","url":null,"abstract":"<p><p>Computerized gait analysis enables objective assessment and quantification of gait disorders in dogs, aiding lameness diagnosis and treatment monitoring. Kinetic analysis examines the forces exerted during movement, whereas kinematic analysis focuses on the movement of body segments without considering forces. Kinetic gait analysis provides insights into overall limb function, whereas kinematic gait analysis allows examination of individual joint movements, enhancing the understanding of normal and altered joint motion. Kinematic gait analysis can be marker-based or markerless, though marker-based systems dominate clinical use. In human medicine, artificial intelligence (AI) is already integrated with markerless systems for kinematic gait analysis, while veterinary research is still emerging. Kinematic gait analysis can be two- and three-dimensional. Three-dimensional (3D) systems offer the highest accuracy, analyzing joint motion in six degrees of freedom, however their high cost and technical complexity currently limit their use to research. Two-dimensional (2D) systems, benefiting from video technology advances, are more affordable and user-friendly. However, these systems capture motion in a single plane only. To date, no ideal computerized gait analysis system exists for dogs that can visualize and analyze kinematic data in real time - such systems are currently available only for kinetic analysis. With AI-driven advances in human motion analysis, canine kinematic gait analysis, regardless of technology (e. g., optical or sensor-based), is expected to become significantly more accessible for veterinary practice. This review outlines the fundamentals of kinematic data acquisition in dogs, summarizes current research, and compares optical gait analysis systems.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 5","pages":"298-307"},"PeriodicalIF":0.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145305312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michèle Bergmann, Ute Klein-Richers, Yury Zablotski, Katrin Hartmann
{"title":"Shedding of feline panleukopenia virus DNA in cats in breeding catteries.","authors":"Michèle Bergmann, Ute Klein-Richers, Yury Zablotski, Katrin Hartmann","doi":"10.1055/a-2694-0145","DOIUrl":"10.1055/a-2694-0145","url":null,"abstract":"<p><p>The present study's aims were to investigate fecal panleukopenia virus (FPV) DNA shedding in cats from breeding catteries and to identify factors associated with shedding, including the presence of diarrhea.239 cats out of 40 catteries were included. Information on catteries and cats were obtained by a breeders' questionnaire. Fecal samples of the cats were classified with the Purina fecal score and analyzed for FPV DNA by quantitative polymerase chain reaction (qPCR). Other gastrointestinal microorganisms were assessed by qPCR/RT-qPCR and fecal flotation. Information on the catteries, cats, and results of fecal sample analyses were statistically analyzed to determine factors that were associated with fecal FPV DNA shedding by Fisher's exact test; p-values <0.05 were considered significant.Six of 239 cats (2.5%) shed FPV DNA with feces. Cycle threshold values of qPCR ranged from 24-37. All FPV DNA-positive cats were coinfected (with either <i>Clostridium</i> spp., <i>Cryptosporidium</i> spp., <i>Giardia</i> spp. and/or feline coronavirus). Fecal consistency of 3/6 FPV DNA-positive samples was diarrheic, and fecal FPV DNA shedding was significantly associated with diarrheic feces (<i>p</i>= 0.015; OR: 9.9, CI<sub>95%</sub>: 1.2-78.7). No other factors significantly influenced FPV DNA shedding.Fecal FPV DNA shedding was rarely observed among healthy cats from breeding catteries but maintaining proper vaccination programs against panleukopenia is crucial. Since FPV DNA shedding was linked to a higher likelihood of diarrheic feces, mild diarrhea in otherwise healthy cats should not be neglected and raise awareness about a potential risk of FPV within the cattery or other multi-cat environments.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 5","pages":"280-287"},"PeriodicalIF":0.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145305121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pemphigus vulgaris - a case report].","authors":"Johanna van den Berg, Katrin Lange","doi":"10.1055/a-2682-4940","DOIUrl":"10.1055/a-2682-4940","url":null,"abstract":"<p><p>Pemphigus vulgaris (PV) represents a rare autoimmune dermatosis. The therapeutic agents of choice are immunosuppressants, which are used in form of a monotherapy or as a combination treatment depending on the clinical picture. This report provides a current literature review and describes a case of pemphigus vulgaris in a 9-year-old, male, castrated, medium-sized mixed-breed dog. The dog presented with characteristic cutaneous and mucosal lesions showing oral mucosal vesicles and ulcerations as well as ulcerations in the periocular region as well as on the planum nasale, tail base, and the paws. Based on the clinical signs and the results of the further and histological examinations, the diagnosis was confirmed. Using long-term immunosuppressive therapy (Prednisolone, Azathioprine) the dog attained complete remission up to the present time.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 5","pages":"308-317"},"PeriodicalIF":0.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145305293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wolfgang Bäumer, Roswitha Merle, Leonie Feuer, Katharina Frenzer, Antina Lübke-Becker
{"title":"[Resistance situation of selected small animal pathogenic bacteria and prudent use of antibiotics - how do I integrate this?]","authors":"Wolfgang Bäumer, Roswitha Merle, Leonie Feuer, Katharina Frenzer, Antina Lübke-Becker","doi":"10.1055/a-2685-0834","DOIUrl":"10.1055/a-2685-0834","url":null,"abstract":"<p><p>As part of a collaborative project funded by the BMEL (\"HKP-Mon\"), we had the opportunity to access a large data set of antimicrobial resistance tests from Laboklin. A total of 175,171 results from the years 2019 to 2021 were available to us for evaluation. These data sets were used to evaluate relevant bacterial pathogens in dogs and cats and their resistance situation. Results on methicillin-resistant <i>Staphylococcus (S.) aureus</i> (MRSA), <i>S. pseudintermedius</i> (MRSP), third-generation cephalosporin-resistant (3GCR) <i>Escherichia (E.) coli</i>, 3GCR <i>Klebsiella (K.) pneumoniae</i> and <i>Pseudomonas (P.) aeruginosa</i> are presented here. About 15% (cats) to 20% (dogs) of <i>S. aureus</i> isolates were characterized as MRSA. For <i>S. pseudintermedius</i>, the MRSP prevalence was on average around 7% for dogs and with 16% higher in cats. Resistance to a third-generation cephalosporin was found in about 12% (both cats and dogs) of <i>E. coli</i> samples and 3GCR <i>K. pneumoniae</i> prevalence was 15% in dogs and 26% in cats. Due to the natural (intrinsic) resistances of <i>P. aeruginosa</i> to a large number of antibiotic classes, the only active substances available in veterinary medicine apart from colistin/polymyxin B are aminoglycosides and fluoroquinolones.The multidrug-resistant bacteria described here therefore pose a considerable challenge in therapeutic terms. Depending on the site of infection, there are often only a few treatment options left. Careful diagnostics and correct interpretation of the microbiological results are therefore essential to maintain the effectiveness of antibiotics and minimize the development of further antibiotic resistance.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 5","pages":"288-297"},"PeriodicalIF":0.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145305292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Analysis of body cavity effusion - focus on cytological examination].","authors":"Imke M von Hohnhorst, Kristina Weiler","doi":"10.1055/a-2620-8113","DOIUrl":"10.1055/a-2620-8113","url":null,"abstract":"<p><p>Body cavity effusion is a common finding in small animal medicine. Fluid analysis is needed in order to determine the underlying pathology. Classification into the categories of protein-poor transudate, protein-rich transudate and exudate is based on the measurement of cell count and protein content. The cytological examination is an important tool for certain effusion variants (e. g. chyle, hemorrhagic effusions, uroperitoneum, biliary effusions, neoplastic effusions) and can complement the biochemical analysis enabling a more precise classification and, in some instances, providing a specific diagnosis. This review article highlights what to look for during the microscopic evaluation, which specific findings can be identified in the different types of effusion, when further diagnostics test are indicated as well as which limitations are to be taken into account.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 4","pages":"236-247"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabrina Pahl, Jan Christian Wohlsein, Svenja Becker, Inken Münch, Andrea Tipold, Peter Wohlsein
{"title":"[Idiopathic eosinophilic meningoencephalomyelitis in a young Belgian Tervueren-shepherd dog].","authors":"Sabrina Pahl, Jan Christian Wohlsein, Svenja Becker, Inken Münch, Andrea Tipold, Peter Wohlsein","doi":"10.1055/a-2632-2477","DOIUrl":"10.1055/a-2632-2477","url":null,"abstract":"<p><p>Eosinophilic meningoencephalitis is a rare neurological disorder, affecting mainly young, male and medium-sized to large breed dogs. This case report describes the clinical signs of a grave and peracute clinical course and pathomorphological findings of a young, female Belgian Tervueren shepherd dog with eosinophilic meningoencephalomyelitis. The dog was presented to emergency service with acute onset of progressive apathy, developing into stupor and lateral recumbency. Despite immediate symptomatic treatment deteriorating consciousness with tetraparesis was noted and finally the dog went into coma associated with decerebrate rigidity. The dog was humanly euthanized on request of the owner 7 hours after presentation in the clinic. Gross pathological examination revealed circumscribed lesions particularly in the white matter of the cerebral cortex. Histologically, a multifocal severe, eosinophilic and granulomatous to necrotizing and lymphohistiocytic meningoencephalomyelitis was observed. In both adrenal glands, a severe eosinophilic and granulomatous inflammation was detected in the medulla. The etiopathogenesis remained undefined and the encephalitis was categorized as \"meningoencephalomyelitis of unknown origin\" (MUO).</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 4","pages":"256-264"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
René Dörfelt, Vera Geisen, Florian Sänger, Saskia Herges, Katrin Hartmann
{"title":"[Monitoring of laboratory diagnostic parameters in critical care patients - Part 1 - Hematology, coagulation and acute-phase-proteins].","authors":"René Dörfelt, Vera Geisen, Florian Sänger, Saskia Herges, Katrin Hartmann","doi":"10.1055/a-2663-5214","DOIUrl":"10.1055/a-2663-5214","url":null,"abstract":"<p><p>Critically ill dogs and cats commonly present with a dysfunction of multiple organ systems, systemic inflammatory response, and infection. The \"Rule of 20\" scheme provides a structured framework to systematically assess these changes, including numerous laboratory diagnostics. This two-part review article summarizes key laboratory tests and their most frequent alterations in critically ill dogs and cats.Part one focuses on hematologic tests, especially the parameters hematocrit, leukocyte count, and platelet count, with common alterations in critically ill patients including anemia, polycythemia, leukocytosis. In addition, changes in the coagulation system, such as hypo- or hypercoagulability, can frequently occur in critically ill patients, therefore these are also discussed. To support the diagnosis of systemic inflammation and infections, the utility of acute-phase-protein analysis and bacteriological examinations is discussed. In addition, myocardial markers are considered as indicators of myocardial injury, as they may occur in systemic inflammatory response and sepsis.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 4","pages":"248-255"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnostic work-up of body cavity effusions in dogs and cats].","authors":"Lisa Kristina Kaiser, Kristina Weiler","doi":"10.1055/a-2632-2428","DOIUrl":"https://doi.org/10.1055/a-2632-2428","url":null,"abstract":"<p><p>Patients with body cavity effusions are often seen in veterinary practice.However, the underlying causes of effusion formation are numerous and to draw conclusions about the underlying pathogenesis, further laboratory diagnostic work-up is essential.An initial classification of the pathomechanism (transudate versus exudate) may already be achieved using simple tools that are generally available in every practice (e. g. refractometer, hematology device/counting chamber, microscope). The effusion analysis includes macroscopic assessment, evaluation of the protein content, determination of the nucleated cell count and, if necessary, red blood cell count or the hematocrit and the cytological evaluation of direct and enrichment preparations (in the case of cell-poor fluids).In some instances, the cultivation of microorganisms (if an underlying infection is suspected) and/or the analysis of certain biochemical parameters may also be indicated; e. g. measurement of triglycerides when chylous effusion is suspected, measurement of creatinine and/or potassium if a uroperitoneum is suspected or the measurement of bilirubin if biliary peritonitis represents a concern.In addition, some studies focus on markers that may be used to differentiate between transudate and exudate as well as between infectious and sterile inflammatory processes (e. g. glucose, lactate, lactate dehydrogenase).This review article provides systematic instructions for the work-up and examination of body cavity effusions in dogs and cats, in order to narrow down potential differential diagnoses wherever possible.Even when sent to a reference laboratory, the correct preparation of the effusion fluid and the information on the patient (signalment, history, pre-medications, clinical examination, imaging and laboratory diagnostic findings) as well as the results of the in-house effusion analysis are important so that the examiners are able to provide the most accurate diagnosis or underlying pathomechanism.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 4","pages":"220-235"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sina Strey, Ina Leiter, Reinhard Mischke, Marion Schmicke, Johanna Rieder
{"title":"[Evaluation of endogenous aldosterone concentrations and thyroid parameters in dogs with hypoadrenocorticism - a pilot study].","authors":"Sina Strey, Ina Leiter, Reinhard Mischke, Marion Schmicke, Johanna Rieder","doi":"10.1055/a-2620-8062","DOIUrl":"10.1055/a-2620-8062","url":null,"abstract":"<p><p>The evaluation of the prevalence of hypoaldosteronism and (autoimmune) hypothyroidism in dogs with hypoadrenocorticismLeft over serum samples from 29 dogs with confirmed hypoadrenocorticism were analyzed. Aldosterone concentrations were determined in 0 h- and 1 h samples of the ACTH-stimulation test. Total T4 concentration (TT4), thyroid-stimulating hormone (TSH) and thyroglobuline antibodies (TgAA) were determined at 0 h and 1 h following the administration of ACTH. Patient data base was searched retrospectively for data on neutrophil-to-lymphocyte ratio as well as sodium (Na), potassium (K), the Na:K ratio and creatinine concentrations.Hypoaldosteronism was detected in 59% (17/29) of dogs with electrolyte imbalances. The aldosterone concentration correlated with the Na:K ratio. Physiologic aldosterone concentrations were identified in 10% (3/29) of patients with electrolyte imbalances. Thyroid parameters suggesting hypothyroidism (low TT4, high TSH) were identified in 10% (3/29) of the study population. Additionally, 2 of these dogs had increased TgAA levels. Three dogs showed increased TSH levels while TT4 was within the reference range.Aldosterone is decreased in most patients with hypoadrenocorticism. Thyroid parameters should be interpreted with care in dogs diagnosed with hypoadrenocorticism.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 4","pages":"202-208"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Paulina Menzel, Sebastian Schaub, Arne Güssow, Joanna Lin, Ve Patzelt, Natali Bauer, Katarina Hazuchova
{"title":"[Evaluation of predictors of chronic kidney disease in hyperthyroid cats following radioiodine treatment - a pilot study].","authors":"Anna Paulina Menzel, Sebastian Schaub, Arne Güssow, Joanna Lin, Ve Patzelt, Natali Bauer, Katarina Hazuchova","doi":"10.1055/a-2563-9702","DOIUrl":"https://doi.org/10.1055/a-2563-9702","url":null,"abstract":"<p><p>Currently, no suitable parameter to predict the occurrence of azotaemic chronic kidney disease (CKD) after hyperthyroidism treatment in cats exists. The aim of this study was to evaluate various clinical and laboratory parameters as well as renal cortical thickness (assessed by ultrasound) as predictors of azotaemic CKD after radioiodine therapy (RAIT).Cats presented for RAIT (April 2021-April 2022) were prospectively enrolled. Cats with azotaemia (creatinine≥140 µmol/L) and cats with pathological renal morphology were excluded. After RAIT, cats were followed for 6-12 months (measurement of total thyroxine [TT4], thyroid-stimulating hormone and creatinine). Cats with persistent hyperthyroidism and cats with a follow-up<6 months were excluded from the statistical analysis, as their thyroid and kidney function could not be sufficiently evaluated. Following parameters obtained prior RAIT were compared between cats that developed azotaemic CKD following RAIT and those that did not: age, weight, duration since the diagnosis of hyperthyroidism and RAIT, blood pressure, haematocrit, concentration of creatinine, urea, potassium, phosphate, TT4 and symmetrical dimethylarginine, urine-specific gravity, urine protein/creatinine ratio and sonographically assessed renal cortical thickness.51 cats were enrolled; 29/51 were included in the statistical analysis (11/29 became euthyroid and 18/29 became hypothyroid post RAIT). There was no difference in the frequency of azotaemia between euthyroid and hypothyroid cats (5/11 vs. 6/18, p=0.7). None of the clinical, laboratory and morphological markers proved to be predictive of the development of azotaemic CKD following RAIT.None of the investigated parameters was predictive of the development of azotaemic CKD in hyperthyroid cats after RAIT. Due to the small study population, future larger studies should be undertaken, especially to assess morphological markers.</p>","PeriodicalId":520818,"journal":{"name":"Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere","volume":"53 4","pages":"209-219"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}