The Malaysian journal of medical sciences : MJMS最新文献

{"title":"The Effectiveness of Dedicated Trauma Operation Theatre and Trauma Intensive Care Unit on the Outcomes of Patients with Traumatic Brain Injury after Emergency Neurosurgery.","authors":"Baiduree Borhan,&nbsp;Wan Mohd Nazaruddin Wan Hassan,&nbsp;Mohamad Hasyizan Hassan,&nbsp;Laila Ab Mukmin,&nbsp;Abd Rahman Izaini Ghani","doi":"10.21315/mjms2022.29.4.12","DOIUrl":"https://doi.org/10.21315/mjms2022.29.4.12","url":null,"abstract":"<p><strong>Background: </strong>A dedicated trauma operation theatre (TOT) and a trauma intensive care unit (TICU) within the same block as the emergency department (ED) can facilitate immediate management and surgery of patients suffering from traumatic brain injury (TBI). The present study compared the effectiveness and outcomes of TBI management between the TOT-TICU and general OT (GOT) and neuro-ICU (NICU) setups.</p><p><strong>Methods: </strong>This was a retrospective cohort study involving 120 patients with TBI who were divided into the GOT-NICU (<i>n</i> = 63) and TOT-TICU (<i>n</i> = 57) groups. Data were obtained from patients' admission and medical records. Demographic data, durations of specific management phases and outcomes of patients were documented.</p><p><strong>Results: </strong>In the TOT-TICU group, the duration of transportation from ED to OT [15 (standard deviation [SD] = 15) min versus 45 (SD = 15) min; <i>P</i> < 0.001], duration of arrival in OT to incision [50 (SD = 30) versus 70 (SD = 23) min; <i>P</i> = 0.005] and duration of transportation from OT to ICU [40 (SD = 17) versus 48 (SD = 30); <i>P</i> = 0.005] were significantly shorter than those in the GOT-NICU group. However, the duration of mechanical ventilation, duration of ICU stays, Glasgow Outcome Scale (GOS) upon discharge and GOS at 3-month post-discharge were comparable between both groups.</p><p><strong>Conclusion: </strong>The TOT-TICU setup shortened the duration of transportation from ED to OT, duration of arrival in OT to incision and duration of transportation from OT to ICU compared with the GOT-NICU setup. Hence, the availability of OT and ICU within the trauma block managed to provide immediate management to TBI patients.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"131-139"},"PeriodicalIF":1.4,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40356840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ellagic Acid Induces in vitro Alkalinisation of the Digestive Vacuole in Drug-Sensitive Plasmodium falciparum Strain.","authors":"Nur Hazirah Muchtar,&nbsp;Nik Nor Imam Nik Mat Zin,&nbsp;Fatin Sofia Mohamad,&nbsp;Nurhidanatasha Abu-Bakar","doi":"10.21315/mjms2022.29.4.5","DOIUrl":"https://doi.org/10.21315/mjms2022.29.4.5","url":null,"abstract":"<p><strong>Background: </strong>Malaria is one of the leading causes of death worldwide caused by parasites of the genus <i>Plasmodium</i>. The reduced efficacy of the mainstay antimalarial drugs due to the widespread of drug-resistant <i>Plasmodium falciparum</i> (<i>P. falciparum</i>) necessitates an effort to develop novel antimalarial drugs with new targets. The effects of a phenolic compound, ellagic acid, against the malaria parasite have previously been reported. This present study aimed to evaluate the effect of ellagic acid on pH of the <i>P. falciparum</i> digestive vacuole.</p><p><strong>Methods: </strong>The antimalarial potential of ellagic acid against the chloroquine-sensitive strain (3D7) of <i>P. falciparum</i> was assessed by using a malarial SYBR Green 1 fluorescence-based (MSF) assay. The effect of different concentrations of ellagic acid on the pH of the parasite's digestive vacuole at mid-trophozoite stage was examined by using a ratiometric pH indicator, fluorescein isothiocyanate (FITC)-dextran on the flow cytometry.</p><p><strong>Results: </strong>The result of the MSF assay showed that ellagic acid has an antimalarial activity (half-maximal inhibitory concentration [IC₅₀] = 1.85 ± 4.57 nM) at par with a standard drug, artemisinin (IC₅₀ = 1.91 ± 5.41 nM). The pH of the digestive vacuole of ellagic acid-treated parasites was significantly changed (pH values ranged from 6.11 to 6.74) in a concentration-dependent manner as compared to untreated parasites (<i>P</i> < 0.001). A similar effect was shown by the parasites treated with a standard proton pump inhibitor, concanamycin A.</p><p><strong>Conclusion: </strong>These findings suggest that ellagic acid might have altered the digestive vacuole pH through the inhibition of proton pumps that regulate the acidification of this organelle. Overall, this study provides a valuable insight into the potential of ellagic acid as a promising antimalarial candidate with a novel mechanism of action.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"43-52"},"PeriodicalIF":1.4,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40356842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opportunistic Risk Screening of Depression by Community Pharmacists: Noble Intervention to Mend the Mind during COVID-19.","authors":"Ramasamy Chidambaram","doi":"10.21315/mjms2022.29.4.15","DOIUrl":"https://doi.org/10.21315/mjms2022.29.4.15","url":null,"abstract":"<p><p>Depression is the most common condition affecting the mental health of individuals. During the whole lifetime, at least one in four individuals go through an episode of this disorder. Recently, the Malaysian number of cases has increased to around 500,000 with more adding due to COVID-19 pandemic. The first professionals to detect depression by analysing the rather emotional, presenting symptoms of the patient are the family physicians. In such circumstances, how is it possible for a community pharmacist to identify undiagnosed depression? Depression is real, sadly, the silent nature of the disorder results in an increase in its unreported cases. On the bright side we believe the new screening guidelines and intervention of community pharmacists might be one noble way to aid in the opportunistic risk screening of depression and heal the hidden emotions during COVID-19.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"160-164"},"PeriodicalIF":1.4,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40355877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Parenting Style and Risk of Attention Deficit Hyperactivity Disorder in Elementary School Children.","authors":"Alma Rossabela Setyanisa,&nbsp;Yunias Setiawati,&nbsp;Irwanto Irwanto,&nbsp;Izzatul Fithriyah,&nbsp;Satria Arief Prabowo","doi":"10.21315/mjms2022.29.4.14","DOIUrl":"https://doi.org/10.21315/mjms2022.29.4.14","url":null,"abstract":"<p><strong>Background: </strong>Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder in a child with three symptoms, which include inattention, hyperactivity and impulsiveness that may persist into adulthood for some conditions. Parenting style is thought to be one part that determines the risk of ADHD in children. This study aims to analyse the relationship between parenting styles and the risk of ADHD in children.</p><p><strong>Methods: </strong>Employing a cross-sectional design, this study was conducted in Surabaya from November 2020 to January 2021. The respondents of the study were parents who had children at risk of ADHD with a total of 55 samples recruited using the purposive sampling technique. The questionnaires used are the demographic questionnaire, Abbreviated Conners Rating Scale (ACRS), and the Parenting Style Questionnaire for Children and Adolescents (KPAA), which were filled out online by the respondents. The data were processed and analysed using the bivariate analysis test, Pearson's chi-squared test, which has a significant value if the <i>P</i>-value < 0.05.</p><p><strong>Results: </strong>The majority of the parents used the authoritative style (94.5%). There was a significant relationship between parenting style and the risk of ADHD in children with <i>P</i> < 0.001 for authoritarian and permissive styles and <i>P</i> = 0.005 for an authoritative style.</p><p><strong>Conclusion: </strong>There is a significant relationship between parenting style and the risk of ADHD in children. This indicates the importance of early diagnosis of ADHD and treating the children with ADHD in the context of family environment, especially from parenting style.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"152-159"},"PeriodicalIF":1.4,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40355871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Barriers to Digitising School-Based Obesity Intervention: An Exploratory Study.","authors":"Norhasniza Yaacob,&nbsp;Ruzita Abd Talib,&nbsp;Amirah Ismail,&nbsp;Mohd Izwan Mahmud","doi":"10.21315/mjms2022.29.4.10","DOIUrl":"https://doi.org/10.21315/mjms2022.29.4.10","url":null,"abstract":"<p><strong>Background: </strong>Schools serve as a focal point in which to engage students and school communities, including teachers, parents and other healthcare providers (e.g. nutritionists), in implementing obesity interventions. Bringing them together is beneficial to ensuring healthy eating among schoolchildren and to creating healthy school environments. However, there are barriers and success factors related to the implementation of such an intervention. Therefore, this study aimed to explore the barriers and success factors to school-based obesity interventions to improve obesity implementation.</p><p><strong>Methods: </strong>An exploratory case study with multiple units of analysis was conducted, including interviews, document analyses and a survey. The interview sessions involved six participants, including teachers and nutritionists. The survey was conducted among 121 participants involving 30 teachers, 78 parents and 13 school canteen operators. Pattern-matching techniques were employed to formulate the results.</p><p><strong>Results: </strong>The barriers consisted of the school system, parental awareness, staff availability, and children's compliance. The success factors included the teachers' role, the nutritional approach used, compliance with the healthy school canteen guidelines, and strong collaboration with the Parent-Teacher Association (PTA) and other agencies.</p><p><strong>Conclusion: </strong>It is necessary to digitise an obesity intervention module with some improvements, including strengthening the broader school community's role and integrating nutrition education with technology to improve implementation.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"98-119"},"PeriodicalIF":1.4,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40355872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of the Neurons, Astrocytes and Particle-Wave Duality in Conventional Electromagnetic Field, Plasma Brain Dynamics and Quantum Brain Dynamics.","authors":"Zamzuri Idris,&nbsp;Zaitun Zakaria,&nbsp;Jafri Malin Abdullah","doi":"10.21315/mjms2021.28.6.1","DOIUrl":"https://doi.org/10.21315/mjms2021.28.6.1","url":null,"abstract":"<p><p>The brain is regarded as the most complex anatomical structure in the human body that executes various functions. The electromagnetic brainwaves or energy with its discrete network is commonly thought of as the sole contributor to various brain functions. However, the discrete pattern of the brain network seems insufficient to explain consciousness, binding problems in neural communication, brain heat, psychiatric manifestations and higher-order of thinking. Therefore, it seems that the brain must possess additional energy for it to have a much higher degree of functional freedom. Plasma brain dynamics (PBD) and quantum brain dynamics (QBD) are two hypothetical brain energies that have a strong scientific basis to exist together with the conventional brain electromagnetic energy. The presence of these energies may explain the puzzling brain functions, thus creating an opportunity to correct any abnormalities arising from them.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"1-7"},"PeriodicalIF":1.4,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Matrix Metalloproteinase-9 Gene Polymorphism and Its Methylation in Stroke Patients.","authors":"Omkar Kalidasrao Choudhari,&nbsp;Anita Rani,&nbsp;Geeta Kampani,&nbsp;Charanjeet Kaur,&nbsp;Ananya Sengupta","doi":"10.21315/mjms2021.28.6.4","DOIUrl":"https://doi.org/10.21315/mjms2021.28.6.4","url":null,"abstract":"<p><strong>Background: </strong>Genetic and environmental factors, along with hypertension, diabetes mellitus and smoking cause accelerated atherosclerosis and, eventually, stroke. Matrix metalloproteinase-9 (MMP-9) are inflammatory mediators of the endoproteinase family, and their polymorphism and methylation are associated with the development of atherosclerosis and stroke. This study explores this association in the Indian population.</p><p><strong>Objective: </strong>To study the association of MMP gene polymorphism and methylation with the risk of stroke.</p><p><strong>Methods: </strong>A case-control study was conducted on 100 admitted patients (both genders) diagnosed with ischaemic stroke. Another 100 healthy subjects, not suffering from any chronic illness or stroke, were taken as controls. All participants were genotyped for rs3918242 (MMP-9) by polymerase chain reaction (PCR) and restriction fragment length polymorphism. Methylation of the MMP-9 gene-promoter region was assessed by methylation-specific PCR.</p><p><strong>Results: </strong>The case (mean age = 61.3 ± 7.36 years old) and control (mean age = 60.68 ± 7.1 years old) groups were age-matched. Among cases, 61 patients were smokers, 55 were diabetic and 53 were hypertensive. A significant risk of ischaemic stroke was associated with the CT genotype (adjusted odds ratio [aOR] = 7.09; <i>P</i> < 0.001), TT genotype (aOR = 19.75; <i>P</i> < 0.001) and T allele (aOR = 10.71; <i>P</i> < 0.001). MMP-9 methylation decreased the risk of stroke (aOR = 0.23; <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>MMP-9 gene-1562C/T polymorphism (SNP rs3918242) (single-nucleotide polymorphism [SNP] rs3918242) is a potential marker to predict ischaemic stroke and constitutes a significant proportion of the general population. Its polymorphism predisposes to ischaemic stroke, while its methylation is protective.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"32-41"},"PeriodicalIF":1.4,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin Adherence and Associated Factors in Patients with Type 2 Diabetes Mellitus Treated in Klang Primary Health Care Centres.","authors":"Nasruddin Azri,&nbsp;Bachok Norsa'adah,&nbsp;Norul Badriah Hassan,&nbsp;Nyi Nyi Naing","doi":"10.21315/mjms2021.28.6.8","DOIUrl":"https://doi.org/10.21315/mjms2021.28.6.8","url":null,"abstract":"<p><strong>Background: </strong>Insulin therapy is necessary for patients with type 2 diabetes mellitus (T2DM) to reach the targeted glycaemic level and prevent complications. This study aimed to determine the proportion of adherence to insulin therapy and the associated factors in patients with T2DM.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 249 patients with T2DM who had been on insulin therapy for at least 2 months in primary care centres of the Ministry of Health in Klang, Malaysia. A validated insulin adherence questionnaire for diabetes mellitus (DM) was used to assess insulin adherence. Data on the sociodemographic characteristics, disease-related factors, treatment-related factors and clinical parameters were extracted from medical records and interviews with patients.</p><p><strong>Results: </strong>The adherence to insulin therapy was 8.43%. The factors associated with insulin adherence were self-monitoring of blood glucose (SMBG) (adjusted odds ratio [AOR]: 5.39; 95% confidence interval (CI): 1.20, 24.13; <i>P</i> = 0.028), exercise (AOR: 3.38; 95% CI: 1.37, 10.03; <i>P</i> = 0.029) and the number of daily insulin injections (AOR: 1.63; 95% CI: 1.09, 2.44; <i>P</i> = 0.017).</p><p><strong>Conclusion: </strong>The adherence to insulin therapy in primary health care centres in Malaysia was very poor. Patients who practiced SMBG, exercised and frequent daily insulin injections were significantly more adherent to insulin therapy.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"76-87"},"PeriodicalIF":1.4,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39800022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties and Factor Structure of the Malay Autism Spectrum Quotient: Children's Version.","authors":"Shazia Iqbal Hashmi,&nbsp;Getrude Cosmas Ah Gang,&nbsp;Agnes Sombuling,&nbsp;Nurul Hudani Md Nawi,&nbsp;Puteri Hayati Megat Ahmad","doi":"10.21315/mjms2021.28.6.11","DOIUrl":"https://doi.org/10.21315/mjms2021.28.6.11","url":null,"abstract":"<p><strong>Introduction: </strong>The Malay autism spectrum quotient, children's version (AQ-Child) is a translated and reduced version of the autism spectrum disorder (ASD) screening instrument. The aim of this study was to test the reliability and validity of the translated Malay version of the questionnaire.</p><p><strong>Methods: </strong>The instrument is a 41-item Likert scale form parental questionnaire designed to screen ASD among children aged 6 years old-12 years old. It was filled out by the parents of 700 children (children with ASD = 47; typically developing children = 653) who were contacted through five special education schools and seven mainstream primary schools.</p><p><strong>Results: </strong>Findings showed that Malay AQ-Child has an internal consistency of 0.82 as a whole scale for 41-items. Receiver operator characteristic analysis showed that the cut score of 63 for the translated, reduced version of the AQ-Child with 41 items had 99% area (95% confidence interval [CI]) under receiver operating characteristic (ROC) curve, and sensitivity and specificity of 93% and 99%, respectively. As for factor structure, principal component analysis (PCA) showed good loading values for most of the items in the instrument.</p><p><strong>Conclusion: </strong>The translated version of the Malay AQ-Child for screening ASD can further facilitate the process of surveillance and early intervention for children who need it.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"108-120"},"PeriodicalIF":1.4,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39800025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of a Mindfulness-Based Intervention on Nurses in Kelantan, Malaysia.","authors":"Nor Asyikin Fadzil,&nbsp;Wei Ooi Heong,&nbsp;Yee Cheng Kueh,&nbsp;Cheng Kar Phang","doi":"10.21315/mjms2021.28.6.12","DOIUrl":"https://doi.org/10.21315/mjms2021.28.6.12","url":null,"abstract":"<p><strong>Background: </strong>Among healthcare workers, nurses have a particularly high risk of stress. Stressful conditions in the workplace increase the possibility of burnout and psychological distress. Short mindfulness-based interventions can help to decrease stress, anxiety and depression. This study aimed to explore the effectiveness of a mindfulness-based intervention in reducing perceived stress, anxiety and depression among public teaching hospital staff nurses.</p><p><strong>Methods: </strong>Thirty-five nurses from various specialities were recruited from Hospital Universiti Sains Malaysia (HUSM). The intervention comprised a 1-day brief mindfulness-based intervention workshop and 1 h group practice session each month for 3 months together with daily follow-up via WhatsApp group. All the participants completed a self-administered sociodemographic questionnaire validated for use in a Malay population. The Depression, Anxiety and Stress Scale 21 (DASS 21) and Perceived Stress Scale 10 (PSS 10) were used to measure perceived stress, anxiety and depression before the intervention, and 3 months later upon completion of the intervention.</p><p><strong>Results: </strong>There was a statistically significant reduction in the scores for stress perception (95% confidence interval [CI]: 0.06, 2.92; <i>P</i> = 0.04) and anxiety (95% CI: 0.06, 2.34; <i>P</i> = 0.04) post-intervention.</p><p><strong>Conclusion: </strong>A brief mindfulness-based intervention was effective in reducing perceived stress and anxiety among nurses.</p>","PeriodicalId":520812,"journal":{"name":"The Malaysian journal of medical sciences : MJMS","volume":" ","pages":"121-128"},"PeriodicalIF":1.4,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39800026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}