Ching-Yu Wang, Claudia L Michaels, Maeve Brin, Dylan B Yates, Caitlin Kelly, Mauda Monger, Makailya Drake, Jessica Schwiesow, Tracy Wynne, Sekiyah Jackson, Kelly Turner, Meredith E Clement, Clare Kelsey, Audrey Hang Hai, Corina T Lelutiu-Weinberger, D Scott Batey, Rebecca Schnall
{"title":"Multilevel Barriers and Facilitators to HIV Care Engagement Among Virally Unsuppressed People Living With HIV in the U.S. Deep South: A Qualitative Study.","authors":"Ching-Yu Wang, Claudia L Michaels, Maeve Brin, Dylan B Yates, Caitlin Kelly, Mauda Monger, Makailya Drake, Jessica Schwiesow, Tracy Wynne, Sekiyah Jackson, Kelly Turner, Meredith E Clement, Clare Kelsey, Audrey Hang Hai, Corina T Lelutiu-Weinberger, D Scott Batey, Rebecca Schnall","doi":"10.1097/JNC.0000000000000701","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000701","url":null,"abstract":"<p><strong>Abstract: </strong>The U.S. South experiences disproportionate HIV-related morbidity and persistently lower viral suppression rates. Achieving Ending the HIV Epidemic goals requires understanding multilevel influences on care engagement among virally unsuppressed people living with HIV. We conducted in-depth qualitative interviews with 30 virally unsuppressed people living with HIV receiving care across Alabama, Louisiana, and Mississippi. Guided by the Modified Social Ecological Model, we examined individual, interpersonal, clinic, community, and policy-level factors shaping engagement and antiretroviral therapy adherence. Participants described intersecting structural and psychosocial barriers, including financial insecurity, transportation challenges, depression, and internalized stigma. Social networks functioned as both support and stigma, particularly within family and faith contexts. Clinics served as critical anchors when providing confidential, holistic services addressing social needs, although inefficiencies and resource constraints disrupted continuity. Persistent discrimination, restrictive policies, funding instability, and HIV criminalization further threatened engagement, underscoring the need for multilevel interventions to improve viral suppression.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149130228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Igor Massari Correia, Chimenny Auluã Lascas C de Moraes, Joana Brilhadori, Jeferson Roberto Collevatti Dos Anjos, Euripedes Barsanulfo Gonçalves Gomide, Jéssica Fernanda Corrêa Cordeiro, Juliana Borges, Dalmo Roberto Lopes Machado, André Pereira Dos Santos
{"title":"Influence of Infection Duration on Physical, Psychological, and Quality of Life Responses to Combined Training in People With HIV in Brazil: A Nonrandomized Clinical Trial Protocol From the CALM-HIV Study.","authors":"Igor Massari Correia, Chimenny Auluã Lascas C de Moraes, Joana Brilhadori, Jeferson Roberto Collevatti Dos Anjos, Euripedes Barsanulfo Gonçalves Gomide, Jéssica Fernanda Corrêa Cordeiro, Juliana Borges, Dalmo Roberto Lopes Machado, André Pereira Dos Santos","doi":"10.1097/JNC.0000000000000700","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000700","url":null,"abstract":"<p><strong>Abstract: </strong>Antiretroviral therapy (ART) has increased life expectancy for people with HIV (PWH), but prolonged infection and ART exposure contribute to early-onset sarcopenia, frailty, and metabolic dysfunction. Combined aerobic and strength training may mitigate these complications, although responses may vary according to clinical history. This clinical trial will include PWH aged 50 years and older, stratified by time since HIV diagnosis and ART exposure. Participants will be allocated to a 12-week, supervised, combined training program (three sessions per week) or a control group. Outcomes include physical performance (strength, frailty, gait), body composition assessed by dual-energy x-ray absorptiometry, biochemical markers (lipid profile, CD4/CD8 ratio, inflammatory biomarkers), and psychosocial measures (quality of life, anxiety, depression, and cognitive function). Findings are expected to clarify differential responses across clinical subgroups and inform personalized exercise prescriptions for aging PWH.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan D Ross, Elizabeth Daubert, Stacey M Cahoon, Ruby Hernandez, Darlene Johnson, Tracey E Wilson, Audrey L French, Mardge H Cohen, Kathleen M Weber
{"title":"Prevalence and Correlates of Joint Pain in Chicago Midlife Women With HIV: A Cross-sectional Study.","authors":"Ryan D Ross, Elizabeth Daubert, Stacey M Cahoon, Ruby Hernandez, Darlene Johnson, Tracey E Wilson, Audrey L French, Mardge H Cohen, Kathleen M Weber","doi":"10.1097/JNC.0000000000000695","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000695","url":null,"abstract":"<p><strong>Abstract: </strong>Joint pain is among the most common and disabling forms of chronic pain in women. Whether joint pain is more prevalent among women with versus without HIV (WWH/WWoH) and contributes to greater impairment is unknown. The Pain, Enjoyment, and General Activity instrument assessed joint pain in midlife WWH versus WWoH to determine associations with frailty, loneliness, and depressive/anxiety symptoms. Moderate/severe pain was more commonly reported in WWH than WWoH (44.1 vs. 38.3%) but not significantly. Women with moderate/severe joint pain were more likely to be prefrail/frail (aOR 3.05; confidence interval [CI]: 1.65-5.63) and report greater depressive symptomology (aOR 2.42; CI: 1.31-4.47), anxiety (aOR 3.38; CI: 1.53-7.43), and loneliness (aOR 1.84; CI: 1.02-3.29). Joint pain is highly prevalent in mid-life WWH and WWoH and associated with frailty, depression, anxiety, and loneliness. Identifying and addressing joint pain and associated conditions may improve multiple health domains in midlife women with and without HIV.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Law to Practice, Emergency Department Leaders' Experiences With Universal HIV Testing in New York City: A Qualitative Research Brief.","authors":"Christine Tagliaferri Rael, Stefanie Mayorga, Tatiana Gonzalez-Argoti, Lilian Ha, Samantha Stonbraker, Yvette Calderon, Susie Hoffman, Ethan Cowan, Laurie J Bauman, Joanne E Mantell","doi":"10.1097/JNC.0000000000000689","DOIUrl":"10.1097/JNC.0000000000000689","url":null,"abstract":"","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salphine Watoyi, Anna Larsen, Eunita Akim, Tessa Concepcion, Jerusha Mogaka, Felix Abuna, Laurén Gómez, Nancy Ngumbau, Ben O Odhiambo, Emma M Nzove, John Kinuthia, Grace John-Stewart, Jillian Pintye
{"title":"Motivations of Pregnant Women Initiating HIV Preexposure Prophylaxis Within Routine Antenatal Clinics Enrolled in a Randomized Trial in Western Kenya.","authors":"Salphine Watoyi, Anna Larsen, Eunita Akim, Tessa Concepcion, Jerusha Mogaka, Felix Abuna, Laurén Gómez, Nancy Ngumbau, Ben O Odhiambo, Emma M Nzove, John Kinuthia, Grace John-Stewart, Jillian Pintye","doi":"10.1097/JNC.0000000000000696","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000696","url":null,"abstract":"<p><strong>Abstract: </strong>Vertical HIV transmission remains a public health challenge in high-burden areas. This cross-sectional study analyzed baseline data from 600 pregnant women without HIV in western Kenya who initiated preexposure prophylaxis (PrEP) between January 2022 and July 2023. We examined associations between participant characteristics, self-perceived HIV risk, and PrEP initiation motivations. Overall, 36.3% reported high HIV risk perception. High self-perceived risk was associated with having multiple sexual partners, high empiric risk scores, intimate partner violence (IPV), and anxiety. Unplanned pregnancies and IPV correlated with specific PrEP motivations. Findings highlight the need for tailored counseling, IPV screening, and integrated maternal and child health services to improve PrEP uptake and reduce vertical transmission.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148922630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Murphy, Patricia A Cioe, Leigh Hubbard, Nicole Schachman, Nyx Gomes, Anne M Teitelman, Susan Ramsey
{"title":"A Commentary on Nurse-Led Pre-exposure Prophylaxis Care in Carceral Settings as a Critical Element to Addressing and Ending the HIV Epidemic.","authors":"Matthew Murphy, Patricia A Cioe, Leigh Hubbard, Nicole Schachman, Nyx Gomes, Anne M Teitelman, Susan Ramsey","doi":"10.1097/JNC.0000000000000683","DOIUrl":"10.1097/JNC.0000000000000683","url":null,"abstract":"<p><strong>Abstract: </strong>Incarceration is deeply intertwined with the global HIV epidemic. Initiating pre-exposure prophylaxis (PrEP) during incarceration and continuing PrEP upon community reentry is a critical component of the HIV epidemic response and is recommended by the World Health Organization and the Centers for Disease Control and Prevention. Despite the impact that offering PrEP to incarcerated populations could have on reducing HIV transmission, particularly given the number of incarcerated individuals likely to be indicated for PrEP use, relatively little is known about the status of PrEP implementation and effective approaches to offering the medication within carceral facilities. Nurse-led approaches to providing PrEP care offer an innovative, cost-effective, and evidence-based approach to addressing many barriers to scaling PrEP use in this unique setting. While some gaps remain about how to best implement nurse-led PrEP care delivery, carceral systems can take steps to expand PrEP use through nurse-led approaches as a key step toward ending the HIV epidemic.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148915051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margaret A Lampe, Kate Buchacz, Xin Anne Yuan, Sahithi Kalari, Alexis Henderson, John Weiser, Athena P Kourtis, Jason Craw, Joseph Prejean, Kimberly Canady, Alexandra Balaji, Linda Beer
{"title":"Characteristics and Needs of US Adult Lifetime Survivors With HIV: A Cross-Sectional Study-Medical Monitoring Project 2015-2022 Cycles.","authors":"Margaret A Lampe, Kate Buchacz, Xin Anne Yuan, Sahithi Kalari, Alexis Henderson, John Weiser, Athena P Kourtis, Jason Craw, Joseph Prejean, Kimberly Canady, Alexandra Balaji, Linda Beer","doi":"10.1097/JNC.0000000000000692","DOIUrl":"10.1097/JNC.0000000000000692","url":null,"abstract":"<p><strong>Abstract: </strong>To characterize U.S. adults with perinatally acquired HIV (lifetime survivors), a cross-sectional analysis of adults at least 18 years old and born with HIV or received an HIV diagnosis within 12 months of birth ( N = 292) using 2015-2022 cycle Medical Monitoring Project data was conducted. Weighted percentages and 95% confidence intervals for demographics, social determinants, and HIV outcomes were calculated. On average, lifetime survivors were 62% women, 58% Black, and 26% Hispanic/Latino; one third were more than 30 years old. Half lived in poverty, 21% had unstable housing, 93% received HIV care, but only 43% had sustained viral suppression over the past 12 months. Most rated their health good or better and were satisfied with HIV care. Lifetime survivors face major socioeconomic challenges and low rates of viral suppression. Expanding adherence support, responsive trauma-informed care, access to long-acting ART, and addressing housing could improve outcomes and quality of life and well-being.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148915065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aneeka Ratnayake-Sargent, Mark Brennan-Ing, Laura Senier, Gloria Horton, Donnamarie Lynch, Brianne Olivieri-Mui
{"title":"Strategies for Promoting Antiretroviral Therapy Adherence Among Participants at a U.S. Long-Term Care Facility for People With HIV: A Qualitative Study.","authors":"Aneeka Ratnayake-Sargent, Mark Brennan-Ing, Laura Senier, Gloria Horton, Donnamarie Lynch, Brianne Olivieri-Mui","doi":"10.1097/JNC.0000000000000690","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000690","url":null,"abstract":"<p><strong>Abstract: </strong>Evidence suggests that HIV antiretroviral therapy (ART) adherence is suboptimal in long-term care (LTC) settings. We studied an HIV-specialized LTC facility to understand how a person-centered care model impacts ART adherence among older adults with HIV (OAWH). We conducted semistructured, in-depth interviews with 11 OAWH and five LTC staff/clinicians asking about barriers and facilitators to ART adherence. Interviews were recorded, transcribed verbatim, and analyzed using deductive and inductive rapid analysis matrices. Three themes emerged: functional support, routines, and fostering resident autonomy, which were achieved by the facility through increased availability of prescribing authorities, highly collaborative efforts in patient care planning, and medication reconciliation that prioritized interdisciplinary communication. The significant social and personal challenges of OAWH preadmission provided context emphasizing the magnitude of improvement from nearly none to 100% ART adherence. This facility's approach may serve as the basis for demonstration projects aimed at revising procedures in non-HIV-specialized LTC facilities.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148893321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colleen Mistler, Christie Idiong, Dini Harsono, Linda S Pescatello, Lydia A Barakat, Sydney Kang, Jaimie P Meyer, E Jennifer Edelman
{"title":"Promoting Physical Activity in the Context of Clinical Care for People With HIV and Unhealthy Substance Use in the United States: A Qualitative Study.","authors":"Colleen Mistler, Christie Idiong, Dini Harsono, Linda S Pescatello, Lydia A Barakat, Sydney Kang, Jaimie P Meyer, E Jennifer Edelman","doi":"10.1097/JNC.0000000000000687","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000687","url":null,"abstract":"<p><strong>Abstract: </strong>Using qualitative methods, we investigated barriers and facilitators to promoting physical activity in an HIV clinic in New Haven, CT. We conducted focus groups with HIV clinicians/staff (n = 12) and interviews among people with HIV with unhealthy substance use (n = 10). Data collection and deductive analysis were guided by the Health Equity Implementation Framework domains. Innovation barriers included lack of evidence-based interventions; facilitators included behavioral strategies and app-based programs. Clinical encounter barriers included lack of protocols and competing priorities; facilitators included discussing the benefits of physical activity. Recipient-level barriers included cost, physical capacity restrictions, and unhealthy substance use; facilitators included social support and tailoring interventions to individual interests/fitness levels. Contextual barriers included budget restrictions and lack of billing options; facilitators included having a physical activity specialist and infrastructure to link patients to physical activity services. Future research should investigate the feasibility of implementing a physical activity intervention into HIV clinical care.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148893287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philemon Domoyeri, Edwin N Aroke, Khalid W Freij, Jasmine K Vickers, David E Vance, Pariya L Fazeli
{"title":"Sleep Quality and Depressive Symptoms Mediate the Relationship Between Pain and Everyday Function: A Cross-Sectional Study of Adults Living With HIV in Birmingham, Alabama.","authors":"Philemon Domoyeri, Edwin N Aroke, Khalid W Freij, Jasmine K Vickers, David E Vance, Pariya L Fazeli","doi":"10.1097/JNC.0000000000000677","DOIUrl":"https://doi.org/10.1097/JNC.0000000000000677","url":null,"abstract":"<p><strong>Abstract: </strong>Pain in people living with HIV (PWH) is associated with greater psychological distress, poor sleep quality, and functional limitations. Yet the interconnections among these relationships remain understudied. Our study examined whether (a) sleep quality mediates the relationship between pain and depressive symptoms, (b) depressive symptoms mediates the relationship between pain and functional limitations, and (c) pain is associated with functional limitations through a serial pathway. A cross-sectional secondary analysis of 261 PWH was conducted. Pain was assessed using the pain subscale from the Medical Outcomes Study HIV Health Survey; lower scores indicated worse pain. Participants also completed the Pittsburgh Sleep Quality Index, the Center for Epidemiologic Studies Depression scale, and the Lawton and Brody Instrumental Activity of Daily Living (IADL) scale. Mediation analysis was performed using age, race, and education as covariates. Sleep quality partially mediated the relationship between pain and depressive symptoms, accounting for approximately 42% of the total effect. Depressive symptoms partially mediated the association between pain and IADL impairments (22%), whereas the serial pathway through sleep and depressive symptoms explained 8.4% of pain's total effect on IADL impairments. Improving sleep quality and depressive symptoms may reduce the negative impacts of pain on everyday functioning.</p>","PeriodicalId":520809,"journal":{"name":"The Journal of the Association of Nurses in AIDS Care : JANAC","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}