The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease最新文献_第2页

Peer-led education on treatment success and patient-reported outcomes in drug-susceptible pulmonary TB. 对药物敏感肺结核的治疗成功和患者报告的结果进行同伴主导的教育。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.26.0102

M G Workie, F Ambaw, M A Asemahegn

{"title":"Peer-led education on treatment success and patient-reported outcomes in drug-susceptible pulmonary TB.","authors":"M G Workie, F Ambaw, M A Asemahegn","doi":"10.5588/ijtld.26.0102","DOIUrl":"10.5588/ijtld.26.0102","url":null,"abstract":"<sec><title>BACKGROUND</title>Peer-led education has shown effectiveness in improving adherence and psychosocial outcomes for HIV and chronic disease through shared experience and social learning. Despite its potential, peer involvement remains underutilised in TB care, particularly in low-income settings. Existing studies primarily focus on microbiological cure and treatment completion with minimal attention to patient-reported outcomes such as quality of life, disability, and mental health.</sec><sec><title>OBJECTIVE</title>The aim of this study is to evaluate the effect of a peer-led educational intervention on treatment success, quality of life, disability, and depression among adults with drug-susceptible pulmonary TB in South Omo and Ari zones, in southern Ethiopia.</sec><sec><title>METHODS</title>A cluster randomised controlled trial will be conducted in 30 randomly selected health facilities, enrolling 250 participants. Data will be collected at three time points using structured questionnaires. Mixed-effects logistic regression will assess treatment outcomes. Changes in quality of life, disability, and depression will be analysed using generalised estimating equations. Statistical significance will be set at P < 0.05 with 95% confidence intervals.</sec><sec><title>CONCLUSION</title>The study aims to provide evidence on whether peer-led education improves TB treatment and psychosocial outcomes, informing patient-centred TB control strategies in Ethiopia.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 9","pages":"409-413"},"PeriodicalIF":3.1,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends in resistance to key TB drugs in Pakistan, 2015-2024. 2015-2024年巴基斯坦主要结核病药物耐药趋势

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.26.0022

R Q Shaikh, M Atif, H Aslam, M Z Samad, M J Khawaja, Q M Abbasi, R Fatima

引用次数: 0

Overall sensitivity of tongue swab Xpert MTB/RIF Ultra testing for TB. 舌拭子Xpert MTB/RIF Ultra检测结核病的总体灵敏度。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.26.0298

M de Vos, B Ajide, C A Moe, J Barrameda, M Chirwa, L Rockman, P de Haas, M Kato-Maeda, B Tasca, J Bimba, C Yu, C M Denkinger, K Kremer, P Nahid, A Cattamanchi, G Theron, M Muyoyeta

引用次数: 0

High levels of recurrent TB in the Philippines: results from a rural community cohort using a pragmatic design. 菲律宾高复发性结核病水平：使用实用设计的农村社区队列结果

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.25.0808

J G Aldaba, M A Catalig, A L Lopez, M M Alejandria, M E V Uy, A M Salonga, M Morales-Dizon, P F Raguindin

{"title":"High levels of recurrent TB in the Philippines: results from a rural community cohort using a pragmatic design.","authors":"J G Aldaba, M A Catalig, A L Lopez, M M Alejandria, M E V Uy, A M Salonga, M Morales-Dizon, P F Raguindin","doi":"10.5588/ijtld.25.0808","DOIUrl":"https://doi.org/10.5588/ijtld.25.0808","url":null,"abstract":"<sec><title>BACKGROUND</title>TB remains a major public health problem in the Philippines, which is among the 30 highest TB-burden countries. While treatment success rates are often used as indicators of programme performance, recurrence rates provide a more objective measure of long-term treatment effectiveness. Currently, the Philippines has limited data on recurrent TB.</sec><sec><title>METHODS</title>This cohort from an active TB surveillance study in San Juan, Batangas (2013-2015), was followed up from March 2018 to January 2022. Recurrent TB, defined as an active TB case diagnosed and treated before with anti-TB drugs, was identified using national guidelines. Socio-demographic and clinical data were obtained from interviews and medical records. Incidence rates (per 1,000 person-years) and factors associated with recurrence were analysed using Cox proportional hazards models.</sec><sec><title>RESULTS</title>A total of 284 individuals were followed up for a median of 7.1 years, during which 71 participants (25%) developed recurrent TB, corresponding to an incidence rate of 38.3 cases per 1,000 person-years. Most recurrent cases were clinically diagnosed (87%) and occurred more than 2 years after the initial episode. Older age and lower socio-economic status were significantly associated with recurrence (P < 0.01).</sec><sec><title>CONCLUSION</title>Using pragmatic study design, we found TB recurrence is common in this high-burden setting.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 9","pages":"389-395"},"PeriodicalIF":3.1,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical significance of Xpert MTB/RIF Ultra trace results in the diagnosis and treatment of TB. Xpert MTB/RIF超微量结果在结核病诊断和治疗中的临床意义。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.25.0551

D Vijayakumar, A Kunoor, A Pradeep, A Ashok, A Kumar

引用次数: 0

Sensitivity of chest X-ray from community screening: a meta-reanalysis of TB prevalence survey data. 社区筛查胸部x线片的敏感性：结核患病率调查数据的荟萃再分析。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.25.0744

Aldomoro Burua, Deus Lukoye, Bruce Kirenga, Sabine Hermans, Frank Cobelens

{"title":"Sensitivity of chest X-ray from community screening: a meta-reanalysis of TB prevalence survey data.","authors":"Aldomoro Burua, Deus Lukoye, Bruce Kirenga, Sabine Hermans, Frank Cobelens","doi":"10.5588/ijtld.25.0744","DOIUrl":"10.5588/ijtld.25.0744","url":null,"abstract":"<sec><title>BACKGROUND</title>Community TB screening using chest X-ray (CXR) is recommended for high-burden settings. The sensitivity of CXR for community screening is regarded high but may be overestimated due to incorporation bias. We conducted a meta-reanalysis of data used to provide more accurate estimates for CXR sensitivity.</sec><sec><title>METHODS</title>We considered 23 studies from a published systematic review and meta-analysis where participants were screened for TB using a combination of TB symptoms and CXR and received bacteriological sputum testing as the reference standard. We compared the sensitivity of CXR among symptom screen-positive study participants to that among all study participants.</sec><sec><title>RESULTS</title>Twenty-one studies were included for the meta-reanalysis. The pooled sensitivity (95% confidence interval) of CXR among symptom screen-positive participants was 86% (83%-90%), lower than the pooled sensitivity based on all study participants (94% [92%-96%]) reported in the original meta-analysis. The pooled difference in sensitivity between the two approaches was 6% (4%-8%).</sec><sec><title>CONCLUSION</title>The sensitivity of CXR among symptomatic participants was lower than the published sensitivity, indicating incorporation bias. The sensitivity among symptomatic participants should be considered the realistic maximum sensitivity for community screening; the combined sensitivity for symptomatic and asymptomatic TB is likely lower.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 9","pages":"396-402"},"PeriodicalIF":3.1,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening, pharmacogenetic testing, and treatment challenges of TB infection in a Thai prison. 泰国监狱中结核病感染的筛查、药物遗传学检测和治疗挑战。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.26.0215

S Fuangprachakorn, S Jittimanee, P Sutipanwihan, S Sriburin, C Sengthong, O Wongsathit, K Munmueng, N Chamkuntod, A Kokiatinun, T Sawangngam, K Janthima, A Chonlathep

引用次数: 0

Factors associated with unsuccessful TB treatment outcomes in children and adolescents in Indonesia, 2018-2023. 2018-2023年印度尼西亚儿童和青少年结核病治疗不成功的相关因素

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-08-28 DOI: 10.5588/ijtld.26.0066

Y A Sekarini, F F Yani, S Suyanto, I W Gede Artawan Eka Putra, T T Pakasi, G B Leksono Adhi

{"title":"Factors associated with unsuccessful TB treatment outcomes in children and adolescents in Indonesia, 2018-2023.","authors":"Y A Sekarini, F F Yani, S Suyanto, I W Gede Artawan Eka Putra, T T Pakasi, G B Leksono Adhi","doi":"10.5588/ijtld.26.0066","DOIUrl":"https://doi.org/10.5588/ijtld.26.0066","url":null,"abstract":"<sec><title>BACKGROUND</title>Non-adherence to TB treatment is associated with substantially increased mortality risk among children, yet determinants of unsuccessful treatment outcomes remain under-recognised. We examined factors associated with unsuccessful TB treatment outcomes among children and adolescents in Indonesia from 2018 to 2023.</sec><sec><title>METHODS</title>We conducted a retrospective cohort study using the National TB Registry, including 509,290 patients aged 0-19 years with evaluated treatment outcomes. Outcomes were classified as successful (cured or treatment completed) or unsuccessful (death, loss to follow-up, or treatment failure). Multivariable logistic regression was used to identify factors associated with unsuccessful outcomes.</sec><sec><title>RESULTS</title>Adolescents aged 10-19 years had higher odds of unsuccessful treatment compared with children aged 0-4 years (adjusted odds ratio [AOR]: 1.25, 95% confidence interval [CI]: 1.21-1.28). The strongest predictors of unsuccessful outcomes were drug-resistant TB (AOR: 21.90, CI: 8.58-60.10), HIV co-infection (AOR: 3.70, CI: 3.35-4.08), and retreatment status (AOR: 1.98, CI: 1.83-2.14). Marked geographic disparities were observed, with significantly higher odds in Eastern Indonesia (AOR: 2.80, CI: 2.71-2.91).</sec><sec><title>CONCLUSION</title>Adolescents and children with drug-resistant TB and HIV co-infection, or those receiving retreatment, face markedly increased risks of unsuccessful outcomes, alongside substantial geographic inequities. Strengthened adherence support and regionally targeted interventions are urgently needed.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 9","pages":"403-408"},"PeriodicalIF":3.1,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing TB diagnosis from tongue swabs: global challenges and marginal strategic opportunities. 加强舌拭子结核病诊断：全球挑战和边缘战略机遇。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-07-31 DOI: 10.5588/ijtld.26.0264

P R Mohapatra, N Kaushik, B Mishra

引用次数: 0

Paediatric central nervous system TB: analysis of a 13-year retrospective cohort. 小儿中枢神经系统结核：13年回顾性队列分析。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-07-31 DOI: 10.5588/ijtld.25.0798

M C Pires, B S Nunes, A M Garcia, A P Lemos, R Valsassina, H Choon, C Conceição, R Lopes da Silva, J P Vieira, T M Silva, C Gouveia, M J Brito, L Varandas

引用次数: 0