The Annals of otology, rhinology, and laryngology最新文献

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Autoimmune Disorders Affecting the Larynx: Review of Laryngoscopic Findings and Approach to Multidisciplinary Management. 影响喉部的自身免疫性疾病:喉镜检查结果和多学科治疗方法的综述。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-06-01 Epub Date: 2026-01-26 DOI: 10.1177/00034894251408704
Aditya Kotla, Emma Thayer, Gatr-Alnada Gheriani, Abigail E Moore, C Blake Simpson, Matthew R Hoffman
{"title":"Autoimmune Disorders Affecting the Larynx: Review of Laryngoscopic Findings and Approach to Multidisciplinary Management.","authors":"Aditya Kotla, Emma Thayer, Gatr-Alnada Gheriani, Abigail E Moore, C Blake Simpson, Matthew R Hoffman","doi":"10.1177/00034894251408704","DOIUrl":"10.1177/00034894251408704","url":null,"abstract":"<p><p>The prevalence of autoimmune diseases has been increasing globally. Many disorders have manifestations within the larynx and patients may present initially to the otolaryngologist with breathing, voice, or swallow concerns. This review focuses on the laryngotracheal manifestations of various autoimmune diseases and associated laryngoscopic abnormalities that commonly occur with autoimmune disease, including infraglottic stenosis, bamboo nodules, cricoarytenoid joint ankylosis, supraglottic stenosis, and multilevel airway stenosis. Commonly implicated autoimmune disorders including granulomatosis with polyangiitis (GPA), ANCA-negative GPA, rheumatoid arthritis, Sjögren's syndrome, systemic lupus erythematosus (SLE), pemphigus vulgaris, ankylosing spondylitis, sarcoidosis, relapsing polychondritis, and IgG4-related disease are reviewed with emphasis on clinical presentation, typical laryngoscopic findings, diagnostic criteria, and therapeutic options specific to the larynx. A systematic multi-disciplinary approach between the otolaryngologist and rheumatologist is presented. Prompt identification of a laryngeal abnormality as being potentially related to autoimmune disease and direct communication with rheumatology colleagues can offer patients medical treatment options in addition to procedural intervention and may offer long-term benefits to laryngeal function and overall disease-specific health.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"476-484"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Pain Management in Acute Otologic Conditions by Otolaryngologists: A Case-Control Study. 耳鼻喉科医师对急性耳科疼痛管理的评估:一项病例对照研究。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-06-01 Epub Date: 2025-12-30 DOI: 10.1177/00034894251406466
Karin Stoliar, Gibril Ali Mustafa, Sabri El Saied, Aviad Sapir, Yotam Heilig
{"title":"Evaluation of Pain Management in Acute Otologic Conditions by Otolaryngologists: A Case-Control Study.","authors":"Karin Stoliar, Gibril Ali Mustafa, Sabri El Saied, Aviad Sapir, Yotam Heilig","doi":"10.1177/00034894251406466","DOIUrl":"10.1177/00034894251406466","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate pain management strategies implemented by otolaryngologists for acute infectious otologic conditions including Acute Otitis Externa (AOE), Acute Otitis Media (AOM) and Bullous Myringitis (BM). The primary objective was to evaluate pain assessment and treatment across these groups. Secondary objectives analyzed repeat visit rates and their association with incident pain, demographic and clinical characteristics.</p><p><strong>Methods: </strong>A retrospective case-control study of 478 patients presenting to the ED between 01/2022 and 01/2023. Otologic cases were evaluated in the otolaryngology ED and included AOE (n = 316) and AOM / BM (n = 95). Controls consisted of patients with conservatively treated ureterolithiasis (n = 67). Data included demographic and clinical variables, along with a structured evaluation of pain documentation, treatment, and discharge plans. For high-scoring discharge plans, the specifics of prescribed medications were analyzed.</p><p><strong>Results: </strong>Otologic patients had a mean visual analog scale (VAS) score of 5.0, compared to ureterolithiasis 6.7. Otologic pain management was less comprehensive, with ED treatment administered to 12% to 13%, compared to 72.6% of ureterolithiasis patients (<i>P</i> < .001). Similarly, only 6% to 14.8% of otologic patients received comprehensive analgesic discharge plans, compared to 71.2% in the ureterolithiasis cohort (<i>P</i> < .001). Opioid-based monotherapy was the primary treatment modality in the otologic groups (86%-90%) compare to more diverse and synergistic, NSAID based regimens in the ureterolithiasis cohort. No differences in ED revisits were observed. Age, sex, ethnicity, and comorbidities did not significantly correlate with pain levels or outcomes.</p><p><strong>Conclusion: </strong>This study reveals shortcomings in pain management in acute otologic conditions. Given the reported inadequacies in pain management training among Otolaryngology trainees, and continued neglect of pain recommendations proposed by specialty- specific clinical practice guidelines, there is an urgent need for analgesic awareness and standardized protocols to ensure consistent and effective care in these everyday conditions.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"409-418"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145867254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Multicenter Observational Study Investigating the Concordance Between Patient-Reported Hearing Loss and Commonly Used Ototoxicity Grading Systems in Patients Treated with Platinum-Based Chemotherapy. 一项前瞻性多中心观察性研究,调查患者报告的听力损失与常用的铂类化疗患者耳毒性分级系统之间的一致性。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-06-01 Epub Date: 2026-01-18 DOI: 10.1177/00034894251408705
Anouk V M Burger, Charlotte W Duinkerken, Eleonoor A R Theunissen, Anouk W M A Schaeffers, Michael Hauptmann, Alexander E Hoetink, Alfons J M Balm, Jan Paul de Boer, Esther Maas-Bannink, Leonie Exterkate, Marije Slingerland, Jeroen C Jansen, Robert J Stokroos, Remco de Bree, Lot A Devriese, Wouter A Dreschler, Tjasse D Bruintjes, Klaske E van Sluis, Charlotte L Zuur
{"title":"A Prospective Multicenter Observational Study Investigating the Concordance Between Patient-Reported Hearing Loss and Commonly Used Ototoxicity Grading Systems in Patients Treated with Platinum-Based Chemotherapy.","authors":"Anouk V M Burger, Charlotte W Duinkerken, Eleonoor A R Theunissen, Anouk W M A Schaeffers, Michael Hauptmann, Alexander E Hoetink, Alfons J M Balm, Jan Paul de Boer, Esther Maas-Bannink, Leonie Exterkate, Marije Slingerland, Jeroen C Jansen, Robert J Stokroos, Remco de Bree, Lot A Devriese, Wouter A Dreschler, Tjasse D Bruintjes, Klaske E van Sluis, Charlotte L Zuur","doi":"10.1177/00034894251408705","DOIUrl":"10.1177/00034894251408705","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to compare the accuracy of the TUNE, American Speech-Language-Hearing Association (ASHA), and Common Terminology Criteria for Adverse Events (CTCAE) grading systems in reflecting the severity of treatment-related hearing loss, as measured by pure-tone audiometry and patient-reported hearing loss using the Speech, Spatial, and Qualities of Hearing scale compare questionnaire (SSQ).</p><p><strong>Methods: </strong>This study is a prospective, multicenter, cross-sectional, and observational study from 2018 to 2024 conducted at the Netherlands Cancer Institute - Antoni van Leeuwenhoek Amsterdam, Leiden University Medical Center, and University Medical Center Utrecht. In this trial, 109 patients with an indication for curative platinum-based chemotherapy (dose ≥ 200 mg/m<sup>2</sup>) were included, of whom 74 were eligible for analysis. Standard frequency and extended high-frequency pure tone audiometry were measured at baseline and follow-up. The SSQ was administered at follow-up to assess patient-reported outcome measures for hearing loss. The TUNE, ASHA, and CTCAE criteria were derived from audiometry. Concordance and Spearman's correlations were evaluated between all 3 grading systems and the SSQ.</p><p><strong>Results: </strong> The concordance of TUNE with the SSQ was 81%. The concordance of CTCAE and ASHA with the SSQ was 73% and 68%, respectively. A statistically significant Spearman's correlation coefficient of -.35 (<i>P</i> = .01) was found between TUNE and the SSQ. The Spearman's correlation coefficient with CTCAE or ASHA and SSQ was -.10 (<i>P</i> = .10) and .04 (<i>P</i> = .75), respectively.</p><p><strong>Conclusion: </strong>This study found that the TUNE is better in reflecting platinum-related patient-reported hearing loss compared to the CTCAE and ASHA.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"443-452"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146000348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Satellite Clinics Increasingly Utilized by Academic Otolaryngology Departments in the United States. 卫星诊所越来越多地利用学术耳鼻喉科在美国。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-30 DOI: 10.1177/00034894251401650
Anirudh Saraswathula, Jonathan H Chen, Carole Fakhry, David W Eisele, Murugappan Ramanathan, Shaun C Desai
{"title":"Satellite Clinics Increasingly Utilized by Academic Otolaryngology Departments in the United States.","authors":"Anirudh Saraswathula, Jonathan H Chen, Carole Fakhry, David W Eisele, Murugappan Ramanathan, Shaun C Desai","doi":"10.1177/00034894251401650","DOIUrl":"10.1177/00034894251401650","url":null,"abstract":"<p><strong>Objectives: </strong>Satellite clinics (ambulatory spaces separate from the main hospital campus), present a growing model of care delivery designed to optimize patient access, quality/safety, and revenue. Our objective was to characterize perceptions of academic otolaryngology chairpersons on satellite clinics to clarify trends in academic practice management.</p><p><strong>Study design: </strong>Survey.</p><p><strong>Setting/methods: </strong>Anonymized survey of US chairpersons of non-military academic otolaryngology departments sent out on May 19 and June 17, 2022 (52/106 [49.1%] response rate).</p><p><strong>Results: </strong>The majority of responding chairpersons lead programs in the South Atlantic (11, 21.2%), Middle Atlantic (9, 17.3%), and Pacific (8, 15.4%), most with over 10 full-time faculty. Faculty seeing patients at satellite clinics are reportedly promoted at the same rate as other faculty in 85.4% of programs and publish as much as their peers at 60.4%. 38.2% (SD 24.8%) of ambulatory volume and 39.7% (SD 25.7%) of ambulatory revenue is reportedly derived from satellite clinics. Half of programs had a satellite clinic-associated ambulatory care center (ASC) handling an estimated 24.8% (SD 17.2%) of their ambulatory operative cases. 71.2% reported residents rotating at satellite clinics and ASCs. Programs unanimously plan to maintain/increase their satellite clinic volume.</p><p><strong>Conclusion: </strong>Satellite clinics represent a critical emerging element in most U.S. academic otolaryngology programs. While these data represent only academic chairpersons and not all faculty, they represent a clear relevance, both academically and financially, for satellite clinics within academic otolaryngology. Most programs plan to increasingly use these satellite clinics in the coming years to expand access for patients while improving clinical efficiency and resident education.</p><p><strong>Level of evidence: </strong>5.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"356-361"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145859784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Clostridioides difficile Infection After Otolaryngologic Surgery: An ACS-NSQIP Analysis. 耳鼻喉外科手术后艰难梭菌感染的危险因素:ACS-NSQIP分析。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-16 DOI: 10.1177/00034894251396752
Matthew Y Liu, Dylan Z Erwin, Melis N Bayrak, David W Jang, Philip G Chen
{"title":"Risk Factors for <i>Clostridioides difficile</i> Infection After Otolaryngologic Surgery: An ACS-NSQIP Analysis.","authors":"Matthew Y Liu, Dylan Z Erwin, Melis N Bayrak, David W Jang, Philip G Chen","doi":"10.1177/00034894251396752","DOIUrl":"10.1177/00034894251396752","url":null,"abstract":"<p><strong>Objective: </strong>To examine the incidence and risk factors of <i>Clostridioides difficile</i> infection (CDI) after otolaryngologic surgery.</p><p><strong>Methods: </strong>A retrospective cohort study of subjects undergoing otolaryngologic surgery was performed using the 2016 to 2021 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP). The incidence of CDI and potential risk factors were assessed.</p><p><strong>Results: </strong>One-hundred eighty-five surgical encounters experienced postoperative CDI out of 149 960, with a CDI incidence of 0.12% (8.8 cases per 10,000 patient-days). The greatest number of postoperative CDI was observed in head and neck reconstructive surgeries. On bivariate analysis, risk factors significantly and practically associated with the occurrence of CDI after otolaryngologic surgery were older age and longer operating times. Multiple logistic regression revealed that the CDI rate did not differ among otolaryngology subspecialties but was influenced by age, functional status, and operating times after controlling for relevant confounders.</p><p><strong>Conclusions: </strong>CDI after otolaryngologic surgery is a serious, costly complication with an incidence comparable to the national CDI rate. Knowledge of the preoperative risk factors associated with CDI may aid in the prevention of such infection after otolaryngologic procedures, thus decreasing patient morbidity and healthcare cost.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"335-341"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Level of Hearing Loss and Associated Factors Among Individuals Aged 5 Years and Above in Ethiopia. 埃塞俄比亚5岁及以上人群的听力损失水平及其相关因素
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-31 DOI: 10.1177/00034894251405679
Waltengus Birhanu, Alene Meshesha, Abebayehu Bedilu, Temesgen Geleta
{"title":"Level of Hearing Loss and Associated Factors Among Individuals Aged 5 Years and Above in Ethiopia.","authors":"Waltengus Birhanu, Alene Meshesha, Abebayehu Bedilu, Temesgen Geleta","doi":"10.1177/00034894251405679","DOIUrl":"10.1177/00034894251405679","url":null,"abstract":"<p><strong>Background: </strong>Hearing loss is a major public health concern, affecting more than 1.57 billion people globally in 2019. According to the disability index, it currently ranks fourth among the global causes of years lived.</p><p><strong>Objective: </strong>to determine the level of hearing loss and its associated factors among individuals aged 5 years and above in Ethiopia.</p><p><strong>Methods: </strong>A population-based National Ethiopian ear and Hearing Survey of 2023, descriptive statistics were used to summarize the sample and outcomes, while ordinal logistic regression models examined the relationship between hearing loss levels and potential predictors.</p><p><strong>Results: </strong>the overall prevalence of hearing loss among individuals aged ≥ 5 years was 15.6%. Significant factors for the severity of hearing loss included older age (odds ratio [OR] = 1.02), ear discharge (OR = 1.84), and eardrum perforation (OR = 1.76).</p><p><strong>Conclusion: </strong>Key factors contributing to the level of hearing loss include age, ear discharge, and eardrum perforation. This underscores the need for enhanced ear health awareness and targeted interventions in primary care to address modifiable risk factors and mitigate the impact of hearing loss.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"383-393"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145867354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Bacterial and Sicca Laryngitis: A Retrospective Cohort and Systematic Review. 慢性细菌性和镰状喉炎:回顾性队列和系统评价。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-30 DOI: 10.1177/00034894251405127
Lauren A Howser, Anuja H Shah, Chandler J Curtis, Shaun A Nguyen, Johnathan M Brown, Kirsten D Meenan
{"title":"Chronic Bacterial and Sicca Laryngitis: A Retrospective Cohort and Systematic Review.","authors":"Lauren A Howser, Anuja H Shah, Chandler J Curtis, Shaun A Nguyen, Johnathan M Brown, Kirsten D Meenan","doi":"10.1177/00034894251405127","DOIUrl":"10.1177/00034894251405127","url":null,"abstract":"<p><strong>Objective: </strong>Chronic bacterial laryngitis (CBL) and sicca laryngitis (SL) are difficult to differentiate as they present and respond to treatment similarly. There are no standardized diagnostic or treatment guidelines. This study aims to better define CBL and SL through a systematic review and retrospective cohort analysis.</p><p><strong>Data sources: </strong>PubMed, Scopus, and CINAHL.</p><p><strong>Review methods: </strong>A systematic review was conducted across PubMed, Scopus, and CINAHL following PRISMA guidelines. Additionally, a retrospective chart review was conducted at a tertiary laryngology clinic, collecting data on symptoms, laryngoscopy findings, treatment, and outcomes.</p><p><strong>Results: </strong>Fourteen studies (n = 718 patients) met inclusion criteria. There were no studies regarding sicca laryngitis; thus, the review reflects patients with CBL. Dysphonia was the most common presenting symptom (85.3%, 95% CI: 63.6-98.1). Common patient factors included proton pump inhibitor use (75.3%) and smoking (57.8% current or former). Frequently isolated pathogens included methicillin-sensitive Staphylococcus aureus (40.3%), methicillin-resistant Staphylococcus aureus (25.6%), and Klebsiella (33.3%). Among treated patients, complete symptom resolution was reported in 48.6%, while 50.2% required retreatment. In the retrospective cohort (n = 21), complete resolution occurred in only 9.5% of patients, with a 38% retreatment rate and 32% recurrence rate. Diabetes was associated with a higher likelihood of retreatment (<i>P</i> = .04). Antibiotics were the primary treatment strategy (71%), but outcomes were variable.</p><p><strong>Conclusions: </strong>CBL and SL are overlapping conditions that present significant diagnostic and therapeutic challenges. The variability in diagnosis and management highlights the need for standardized guidelines and targeted treatment strategies to improve patient care.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"374-382"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145867272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-Specific Risk and Severity of CRS among Cystic Fibrosis Carriers: A Population-Based Cohort Study. 囊性纤维化携带者的年龄特异性CRS风险和严重程度:一项基于人群的队列研究
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-29 DOI: 10.1177/00034894251402953
Aaron C Miller, D Erik Boonstra, Joseph E Cavanaugh, Mahmoud H Abou Alaiwa, Alejandro P Comellas, Douglas B Hornick, David A Stoltz, Philip M Polgreen
{"title":"Age-Specific Risk and Severity of CRS among Cystic Fibrosis Carriers: A Population-Based Cohort Study.","authors":"Aaron C Miller, D Erik Boonstra, Joseph E Cavanaugh, Mahmoud H Abou Alaiwa, Alejandro P Comellas, Douglas B Hornick, David A Stoltz, Philip M Polgreen","doi":"10.1177/00034894251402953","DOIUrl":"10.1177/00034894251402953","url":null,"abstract":"<p><strong>Background: </strong>Chronic rhinosinusitis (CRS) is an inflammatory disease characterized by congestion and nasal discharge, facial pain and pressure, and loss of smell, with symptoms lasting longer than 3 months. CRS is common among people with cystic fibrosis (CF) and CF carriers are also more at risk for CRS than non-CF carriers. We evaluate risk for CRS across the lifespan for CF carriers and determine how CF carriers with CRS may differ from non-CF carriers with chronic sinusitis.</p><p><strong>Methods: </strong>Using 2001 to 2022 MarketScan data, we developed 2 study populations: (1) a matched cohort consisting of CF carriers who were matched to non-CF carriers, and (2) a cohort of patients with chronic sinusitis. We used the matched cohorts of CF carriers and non-CF carriers to estimate age-group-specific incidence rate ratios for experiencing chronic sinusitis. Next, we used the chronic-sinusitis cohort to compare the severity of chronic sinusitis events between CF carriers and non-carriers. Specifically, we estimated the odds of a sinus procedure or the receipt of antibiotic prescriptions to evaluate the severity and healthcare utilization among CF carriers and non-carriers with CRS. Finally, we compared the odds for developing other CF-related conditions among CF carriers with CRS to non-CF carriers with CRS.</p><p><strong>Results: </strong>We found that CRS incidence for CF carriers relative to non-CF carriers was highest for those above 40 years of age. We also found that among people with CRS, CF carriers were more likely to undergo a diagnostic evaluation and endoscopic sinus surgery. CF carriers were also more likely to fill antibiotic prescriptions, use multiple antibiotics, and take antibiotics for longer periods.</p><p><strong>Conclusions: </strong>CF carriers are more likely than non-carriers to suffer from CRS, have more severe CRS, and to exhibit certain features of CF-associated CRS.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"362-373"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145859746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Tinnitus Interventions: An Umbrella Review of Systematic Reviews with Meta-Analysis. 耳鸣干预的结果:综合系统综述和meta分析。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-29 DOI: 10.1177/00034894251394754
Kaiwen Chen, Neil P Monaghan, Shaun A Nguyen, Warren B Chun, John F Mills, Emily Brennan, Ted A Meyer
{"title":"Outcomes of Tinnitus Interventions: An Umbrella Review of Systematic Reviews with Meta-Analysis.","authors":"Kaiwen Chen, Neil P Monaghan, Shaun A Nguyen, Warren B Chun, John F Mills, Emily Brennan, Ted A Meyer","doi":"10.1177/00034894251394754","DOIUrl":"10.1177/00034894251394754","url":null,"abstract":"<p><strong>Objectives: </strong>Tinnitus is a highly prevalent and challenging neurotologic condition affecting over 740 million individuals worldwide. Despite the growing number of studies, treatment approaches remain fragmented and inconsistent. This umbrella review aims to aggregate results from systematic review to comprehensively synthesize the available evidence.</p><p><strong>Methods: </strong>Following PRISMA guidelines, we systematically searched CINAHL, COCHRANE Library, PubMed, and Scopus through April 2025. Systematic reviews with meta-analyses of primary tinnitus interventions were included. Outcomes focused on validated measures of tinnitus severity, distress, loudness, and quality of life. Study quality was assessed using AMSTAR-2.</p><p><strong>Results: </strong>A total of 44 systematic reviews were included, covering 7 intervention domains. Cognitive behavioral therapy (CBT), hearing aids, tinnitus retraining therapy (TRT), and sound/music therapy consistently improved tinnitus-related outcomes (eg, THI reductions up to -14.50, <i>P</i> < .001). Cochlear implantation yielded the largest effects (eg, THI -29.97) but is reserved for patients with moderate-to-profound sensorineural hearing loss who are not adequately helped by hearing aids. Neuromodulation and acupuncture showed modest or inconsistent benefits with high heterogeneity.</p><p><strong>Conclusions: </strong>This umbrella review provides the current and comprehensive analysis of tinnitus treatments. CBT, hearing aids, TRT, and sound/music therapy show consistent benefit. Cochlear implantation offers the greatest effect in patients with moderate-to-profound hearing loss unresponsive to hearing aids. Other therapies show mixed evidence. These findings offer a much-needed evidence framework to guide treatment decisions and future research.</p>","PeriodicalId":520787,"journal":{"name":"The Annals of otology, rhinology, and laryngology","volume":" ","pages":"342-355"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145859740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geographical and Temporal Trends in Industry Engagement Among Otolaryngologists 2017 to 2023. 2017 - 2023年耳鼻喉科医师行业参与的地理和时间趋势。
The Annals of otology, rhinology, and laryngology Pub Date : 2026-05-01 Epub Date: 2025-12-12 DOI: 10.1177/00034894251397440
Christie Hung, Jamie Schlacter, Elliot Morse
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