Airways Without Borders: Establishing Global Airways Units for Integrated Care.

Abstract

Chronic respiratory diseases continue to be managed within fragmented specialty-based structures despite robust evidence supporting the "global airways" concept, which recognizes allergic rhinitis, chronic rhinosinusitis, and asthma as interconnected manifestations of a shared inflammatory continuum. Advances in endotype-driven classification, the treatable traits framework, and the cross-efficacy of biologic therapies have reinforced the scientific and therapeutic rationale for integrated care; however, implementation remains largely theoretical. This editorial advocates for the establishment of Global Airways Units (GAUs), a pragmatic, multidisciplinary model in which otolaryngologists, pulmonologists, and allergists jointly evaluate patients within a unified diagnostic and therapeutic framework. By aligning healthcare organization with established pathophysiological knowledge and evolving guideline recommendations, GAUs represent a feasible, cost-effective strategy to operationalize precision medicine across the entire airway spectrum and translate consensus into tangible clinical benefit.