Sleep & breathing = Schlaf & Atmung最新文献

{"title":"Plasma p-tau217 and neurodegeneration-related biomarkers predict incident cognitive impairment in obstructive sleep apnea: a prospective cohort study.","authors":"Chaofan Geng, Chen Chen","doi":"10.1007/s11325-026-03835-4","DOIUrl":"10.1007/s11325-026-03835-4","url":null,"abstract":"<p><strong>Background: </strong>Obstructive sleep apnea (OSA) is associated with cognitive decline, but biomarkers for identifying cognitively unimpaired patients at increased future risk remain limited. We evaluated the prognostic value of plasma biomarkers associated with neuroaxonal injury and Alzheimer's disease-related biology in OSA.</p><p><strong>Methods: </strong>In this prospective cohort study, 286 cognitively unimpaired adults with polysomnography-confirmed OSA underwent baseline measurement of plasma NfL, GFAP, p-tau181, p-tau217, Aβ42, and Aβ40 and were followed for incident cognitive impairment. Cox regression, predictive performance analyses, and linear mixed-effects models were used.</p><p><strong>Results: </strong>During a median follow-up of 4.18 years, 68 participants (23.78%) developed incident cognitive impairment. In fully adjusted Cox models, each 1-SD increase in NfL was associated with a 46% higher risk of incident cognitive impairment (HR = 1.46, 95% CI 1.17-1.83, P = 0.001), and each 1-SD increase in p-tau217 was associated with a 58% higher risk (HR = 1.58, 95% CI 1.25-2.00, P < 0.001). When modeled jointly, both NfL (HR = 1.34, 95% CI 1.06-1.69, P = 0.014) and p-tau217 (HR = 1.47, 95% CI 1.14-1.89, P = 0.003) remained associated with incident cognitive impairment. In longitudinal analyses, higher baseline NfL and p-tau217 were also associated with faster annual declines in MoCA scores when modeled jointly (NfL × time: β = -0.10, 95% CI - 0.18 to - 0.02, P = 0.014; p-tau217 × time: β = -0.16, 95% CI - 0.25 to - 0.07, P = 0.001). Adding both biomarkers to the clinical model increased the C-index from 0.72 to 0.81 and the 4-year time-dependent AUC to 0.81; the optimism-corrected C-index was 0.79.</p><p><strong>Conclusions: </strong>Higher plasma NfL and p-tau217 levels were independently associated with incident cognitive impairment and faster longitudinal cognitive decline in cognitively unimpaired patients with OSA.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 6","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of web-based education on NIV-related side effects and insomnia severity in COPD patients using home NIV: a randomized controlled trial.","authors":"Şahabettin Eriş, Fatma Gündogdu","doi":"10.1007/s11325-026-03833-6","DOIUrl":"10.1007/s11325-026-03833-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effect of web-based education on NIV-related side effects and insomnia severity in COPD patients using home noninvasive ventilation (NIV).</p><p><strong>Methods: </strong>This randomized controlled trial was conducted with 75 patients between October 2023 and May 2024. Data were collected using the S³-NIV Questionnaire and the Insomnia Severity Index (ISI). The intervention group received web-based education regarding NIV-related side effects and insomnia management. Independent samples t-tests were used to compare numerical descriptive characteristics between groups, while Pearson chi-square and Fisher's exact tests were used for categorical variables. Repeated-measures ANOVA was performed to evaluate changes over time and between groups.</p><p><strong>Results: </strong>Compared with the control group, the intervention group demonstrated significantly higher total S³-NIV Questionnaire scores and higher respiration, sleep, and side-effect subscale scores at weeks 4 and 8. Significant group × time interaction effects were observed for total S³-NIV scores (p < 0.001, η²p = 0.753) and ISI scores (p < 0.001, η²p = 0.352). For insomnia severity, no significant between-group difference in ISI scores was observed at Week 4, whereas ISI scores were significantly lower in the intervention group at Week 8.</p><p><strong>Conclusion: </strong>Web-based education may help improve patient-reported NIV-related symptoms and reduce insomnia severity in patients with COPD using home NIV. These findings suggest that web-based educational interventions may support symptom management and patient adaptation in clinical practice.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploratory analysis of electroencephalogram activity preceding nocturnal enuresis episodes using home-based sleep monitoring.","authors":"Hirokazu Ikeda, Tsuneki Watanabe, Takahiro Ono, Chisato Oyake, Yuta Onuki, Yoshitaka Watanabe","doi":"10.1007/s11325-026-03831-8","DOIUrl":"10.1007/s11325-026-03831-8","url":null,"abstract":"<p><strong>Purpose: </strong>Sleep-wake mechanisms are implicated in the pathophysiology of nocturnal enuresis; however, evidence-based treatments for arousal dysfunction remain lacking. We previously demonstrated prolonged REM sleep latency on wet nights using home-based EEG. This exploratory study analyzed EEG spectral power immediately before enuresis onset to characterize electrophysiological changes associated with arousal dysfunction.</p><p><strong>Methods: </strong>Among 64 children with primary nocturnal enuresis who underwent home-based single-channel portable EEG monitoring, 18 with both a wet and a dry night recorded within 7 days and an alarm-documented time of enuresis were retrospectively analyzed. Absolute spectral power was calculated by fast Fourier transformation for five frequency bands (delta, theta, alpha, sigma, beta) and total power in 30-s epochs. EEG data at 30, 10, and 5 min before enuresis onset on wet nights were compared with the corresponding clock time on dry nights using the Wilcoxon signed-rank exact test.</p><p><strong>Results: </strong>No significant differences were observed at 30 min before enuresis in any frequency band. Delta-band power was significantly higher on wet nights at 10 min (p = 0.040, Cohen's d = 0.38) and 5 min (p = 0.020, d = 0.43) before onset, as was total power at 5 min (p = 0.027, d = 0.38). No differences were found in other frequency bands at any time point.</p><p><strong>Conclusions: </strong>Delta-band power was higher on wet nights at 10 and 5 min before enuresis, with the wet-dry difference widening toward onset, which may reflect transient deepening of sleep. These exploratory findings warrant confirmation in larger studies.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between sleep impairment and gestational diabetes mellitus subtypes: A prospective cohort study.","authors":"Niannian Chen, Dongmei Wei, Chang Gao, Fanfan Chan, Wanqing Xiao, Jinhua Lu, Chi Chiu Wang, Ronald C W Ma, Jianrong He, Xiu Qiu","doi":"10.1007/s11325-026-03823-8","DOIUrl":"10.1007/s11325-026-03823-8","url":null,"abstract":"<p><strong>Aims: </strong>To examine the association of sleep impairment with gestational diabetes mellitus (GDM) and its subtypes.</p><p><strong>Methods: </strong>29,183 pregnant women from the Born in Guangzhou Cohort Study were included. Information on sleep quality, sleep duration and sleep-disordered breathing (SDB) symptoms were collected. GDM was diagnosed using a 75 g, 2h oral glucose tolerance test and medical records. GDM was categorised into three subtypes. Poisson regression models were performed.</p><p><strong>Results: </strong>In total, 4713 (16.2%) were diagnosed with GDM. Poor sleep quality, short nighttime sleep duration and SDB symptoms were associated with increased risks of GDM, with adjusted RR of 1.07 (95% CI 1.01, 1.13), 1.12 (95% CI 1.04, 1.22) and 1.19 (95% CI 1.10, 1.30), respectively. Short nighttime sleep duration and SDB symptoms were also associated with higher risks of the subtype of combined impaired fasting glucose and impaired glucose tolerance (IFG + IGT) (RR 1.55, 95% CI 1.22, 1.96; RR 1.80, 95% CI 1.42, 2.29, respectively). Long nighttime sleep duration was associated with lower risks of the subtype of isolated impaired glucose tolerance (i-IGT) (RR 0.89, 95% CI 0.80, 0.99).</p><p><strong>Conclusions: </strong>Our findings indicate that pregnant women with sleep impairment are more likely to develop GDM, especially the IFG + IGT subtype. Reducing sleep impairment, particularly SDB symptoms, may be a target for intervention to prevent GDM.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subjective and objective sleep quality during late pregnancy and the association with maternal gut microbiota in Chinese pregnant women.","authors":"Tianzi Zang, Jun Liu, Yiming Tu, Huan Tian, Zihan Wang, Zijun Feng, Zhijie Zou, Jinbing Bai, Yanqun Liu","doi":"10.1007/s11325-026-03829-2","DOIUrl":"10.1007/s11325-026-03829-2","url":null,"abstract":"<p><strong>Background: </strong>The incidence of sleep disorders is relatively high among women in late pregnancy. Several studies have indicated that the gut microbiota play a significant role in circadian rhythms and sleep health. The purpose of this study was to explore the association of gut microbiota and sleep quality in pregnant women.</p><p><strong>Methods: </strong>There were 75 pregnant women recruited for this cross-sectional study. The subjective and objective sleep quality were evaluated using the Pittsburgh Sleep Quality Index and Actigraphy. The objective sleep measured total night-sleep time (TST), sleep efficiency (SE), and wake after sleep onset (WASO). The gut microbiota was detected by 16 S rRNA sequencing. LEfSe analysis was used to analyze the differences in gut microbiota among different sleep quality groups, and logistic regression models were used to analyze the association between gut microbiota and sleep quality.</p><p><strong>Results: </strong>In the normal objective sleep quality group and poor objective sleep quality group, the abundances of [Eubacterium]_xylanophilum_group (aOR = 0.329, 95% CI = 0.132, 0.817) and Acetitomaculum (aOR = 0.013, 95% CI = 0.000171, 0.996) were negatively associated with objective sleep quality. In the high TST group and low TST group, the abundances of Bacteroides (aOR = 2.266, 95% CI = 1.065, 4.820), Lachnospiraceae_ND3007_group (aOR = 2.651, 95% CI = 1.116, 6.302), and Lachnospiraceae_UCG-001 (aOR = 2.107, 95% CI = 1.024, 4.334) had a positive relationship with TST.</p><p><strong>Conclusion: </strong>This study identified associations between gut microbiota composition and sleep quality in pregnant women. Specific gut microbiota, including Bacteroides and [Eubacterium]_xylanophilum_group were associated with sleep-related measures. These findings provide suggestive evidence of a potential association between the gut microbiota and sleep health during pregnancy.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise capacity of patients with obstructive sleep apnea at moderate to high altitude.","authors":"Yunchao Huang, Demei Jia, Qifen Jiang, Chunmei Pan, Bin Ma, Huiling Luo","doi":"10.1007/s11325-026-03819-4","DOIUrl":"10.1007/s11325-026-03819-4","url":null,"abstract":"<p><strong>Background: </strong>It remains unknown to what extent exercise capacity is diminished at moderate to high altitudes in patients with obstructive sleep apnea (OSA).</p><p><strong>Purpose: </strong>The primary aim was to compare peak oxygen uptake per kilogram body weight (VO₂/kg) between OSA patients and healthy controls (HCs) at moderate-to-high altitude (~ 1,900 m) using cardiopulmonary exercise testing (CPET). Secondary aims were to evaluate the associations of OSA severity (apnea-hypopnea index, AHI) and nocturnal hypoxemia (lowest oxygen saturation, LSpO₂; oxygen desaturation index, ODI) with CPET parameters, and to explore the potential discriminatory performance of CPET indices.</p><p><strong>Methods: </strong>This prospective study enrolled 38 OSA patients (AHI ≥ 5 events/h) and 36 healthy controls from Kunming, Yunnan Province, China (study site altitude: ~1,900 m; participants' residence altitude range: 1,800-2,800 m above sea level). All participants underwent overnight polysomnography and symptom-limited CPET using a cycle ergometer ramp protocol. Both groups were subgrouped by apnea-hypopnea index (AHI) severity and by lowest oxygen saturation (LSpO₂) for CPET comparisons.</p><p><strong>Results: </strong>After adjustment for BMI, the OSA group exhibited significantly lower VO₂/kg (P = 0.013) and a significantly higher VE/VCO₂ slope (P = 0.038) compared with healthy controls. AHI and ODI were negatively correlated, and LSpO₂ positively correlated, with VO₂/kg; LSpO₂ was positively correlated with VO₂/WR but negatively correlated with VE/VCO₂ slope; ODI was positively correlated with VE/VCO₂ slope. Additionally, in an exploratory ROC analysis, VO₂/kg showed a modest AUC (0.69), high sensitivity (97.4%) and limited specificity (38.9%), suggesting a supportive rather than standalone screening role.</p><p><strong>Conclusions: </strong>OSA patients at moderate-to-high altitude show reduced exercise capacity (lower VO₂/kg) and ventilatory inefficiency (higher VE/VCO₂ slope), correlating with OSA severity and nocturnal hypoxemia; the VO₂/kg and VE/VCO₂ slope differences persisted after adjustment for BMI. These limitations may reflect superimposed chronic intermittent and environmental hypoxia, with skeletal muscle dysfunction, altered ventilatory control, and endothelial impairment as possible contributing mechanisms. CPET provides valuable functional assessment; in an exploratory analysis, CPET parameters may serve as supportive indicators to raise suspicion for OSA but cannot replace polysomnography. Validation in larger, multi-center cohorts is required.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149140406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of CPAP therapy on geriatric depression scale scores in elderly patients with obstructive sleep apnea.","authors":"Ayşe Baha, Caner Baysan","doi":"10.1007/s11325-026-03828-3","DOIUrl":"10.1007/s11325-026-03828-3","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to investigate the effect of CPAP treatment on depression scores in OSA, which is associated with impaired quality of life and functional decline in the geriatric population.</p><p><strong>Methods: </strong>The study was an ambispective cohort involving geriatric patients aged 65-80 with moderate-to-severe OSA confirmed by polysomnography. Initial depressive symptoms were assessed using the Geriatric Depression Scale (GDS). Participants were categorized based on their adherence to CPAP. Objective CPAP usage data, including mean nightly usage time and the percentage of nights used, were obtained from device downloads. Baseline predictors of depression were examined using multiple linear regression. The effect of CPAP adherence on post-treatment GDS scores was analyzed with analysis of covariance (ANCOVA), adjusting for initial depression scores. The model was also run with body mass index, lowest oxygen saturation and follow-up duration as additional covariates, and effect sizes were calculated.</p><p><strong>Results: </strong>Of the 53 patients, 31 (58.5%) adhered to CPAP. Demographic and clinical characteristics were similar between adherent and non-adherent groups. Regression analysis showed that lower nocturnal oxygen saturation (p = 0.012) and higher body mass index (BMI) (p = 0.011) were independently associated with higher initial GDS scores, while the apnea-hypopnea index was not significantly related to depressive symptoms. After adjusting for initial GDS scores, the adherent group had significantly lower post-treatment depression scores compared to non-adherents (adjusted mean GDS: 7.15 ± 0.18 vs. 10.10 ± 0.21, p < 0.001). The adjusted mean difference was 2.95 points (95% CI 2.40-3.50; partial η² = 0.70). Mean nightly use was 6.44 ± 0.97 h in the adherent group and 2.41 ± 0.95 h in the non-adherent group, on 88.4 ± 15.0% and 36.0 ± 25.0% of nights respectively (p < 0.001).</p><p><strong>Conclusions: </strong>CPAP adherence was associated with a significant reduction in depressive symptoms in older adults with OSA. Nocturnal hypoxemia and obesity were key predictors of depression severity. These findings suggest that effective OSA treatment may improve mental health outcomes in the elderly.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149130255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLP-1 receptor agonists for obstructive sleep apnea: a meta-analysis of randomized controlled trials.","authors":"Giulia Carvalhal, Maria Meritxell Roca Mora, Gonzalo Alberto Peralta-Jiménez, Laith Ayasa, Vivian Barrera, Kavita Advani, Jafar Aljazeeri","doi":"10.1007/s11325-026-03826-5","DOIUrl":"10.1007/s11325-026-03826-5","url":null,"abstract":"<p><strong>Purpose: </strong>Weight reduction is recommended in all overweight and obese patients with obstructive sleep apnea (OSA). Glucagon-like peptide-1 (GLP-1) receptor agonists-based therapies have demonstrated clinical benefits in reducing weight and could potentially improve OSA outcomes. We aim to analyze the efficacy and safety of GLP-1 receptor agonists-based therapies in patients with moderate-to-severe OSA.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) that compared GLP-1 receptor agonists-based therapies versus control in adults with moderate-to-severe OSA. We systematically searched electronic databases and registries up to February 10, 2025. Outcomes assessed included apnea-hypopnea index (AHI), body weight, oxygen desaturation index (ODI), minimum oxygen saturation, systolic blood pressure (SBP), diastolic blood pressure (DBP), and adverse events.</p><p><strong>Results: </strong>A total of 6 RCTs involving 1,069 participants were included, four evaluating liraglutide and two tirzepatide. Compared with control, GLP-1 receptor agonist-based therapies reduced AHI by - 9.99 events/hour (95% CI, - 16.47 to - 3.50; p < 0.01; I² = 87%) and body weight by - 9.68 kg (95% CI, - 15.84 to - 3.51; p < 0.01; I² = 98%). These therapies also reduced SBP by -4.77 mmHg (95% CI, -7.04 to -2.51; p < 0.01), and DBP by -1.41 mmHg (95% CI, -2.71 to -0.11; p = 0.03). No significant differences were observed in ODI or minimum oxygen saturation. GLP-1 receptor agonists-based therapies did not increase the risk of adverse events.</p><p><strong>Conclusion: </strong>GLP-1 receptor agonist-based therapies reduced AHI and body weight in the populations studied. Substantial heterogeneity limits interpretation of the pooled effect magnitude. These findings support their potential role within comprehensive OSA management but do not establish them as substitutes for CPAP.</p><p><strong>Registry: </strong>International Prospective Register of Systematic Reviews; No.: CRD42024564018; URL: https://www.crd.york.ac.uk/prospero/ .</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149122387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of stellate ganglion block on postoperative sleep disturbance: a systematic review and meta-analysis.","authors":"Kuilin Wu, Yanting Gao, Xiujuan Gao","doi":"10.1007/s11325-026-03825-6","DOIUrl":"10.1007/s11325-026-03825-6","url":null,"abstract":"<p><p>Postoperative sleep disturbance (PSD) is common after surgery and is characterized by insomnia, fragmented sleep, altered sleep-wake patterns, and excessive daytime sleepiness. Stellate ganglion block (SGB) modulates sympathetic activity and may improve sleep through autonomic, analgesic, and anti-inflammatory mechanisms. We searched eight Chinese and international databases from inception to January 1, 2025, and included 10 randomized controlled trials involving 734 participants, predominantly from China. Compared with placebo, routine care, or active control, SGB was associated with lower subjective sleep scores on the night of surgery (standardized mean difference [SMD], - 2.09; 95% confidence interval [CI], - 3.36 to - 0.83), postoperative day 1 (SMD, - 2.27; 95% CI, - 2.85 to - 1.68), postoperative day 3 (SMD, - 1.12; 95% CI, - 1.70 to - 0.55), and 4 weeks after surgery (SMD, - 1.16; 95% CI, - 1.55 to - 0.77). The 4-week effect remained statistically significant; however, no formal interaction test was performed, and the numerical differences between time points should not be interpreted as evidence of a statistically significant temporal decline. SGB also increased total sleep time by approximately 72 min (mean difference, 71.76 min; 95% CI, 51.51-92.01). The estimate for sleep efficiency was based on only two studies and showed substantial heterogeneity (mean difference, 11.45% points; 95% CI, 1.79-21.11; I² = 86%). Substantial heterogeneity for subjective sleep quality (I² = 90%) and the limited geographic diversity of the included trials reduce the certainty and generalizability of the findings. SGB may improve postoperative sleep, particularly during the early postoperative period, but larger multicenter randomized controlled trials are required.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between weather variables and sleep architecture: A large-scale analysis using consumer sleep data.","authors":"Minji Lee, Hyuntak Hong, Seunghun Kim, Sunyoung Kang, Sooyeon Kim, Sungeun Moon, Jung Kyung Hong, Ki-Young Jung, Dongheon Lee, In-Young Yoon","doi":"10.1007/s11325-026-03824-7","DOIUrl":"10.1007/s11325-026-03824-7","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the impact of daily weather conditions on sleep architecture and assessed whether these effects vary according to the severity of suspected sleep-disordered breathing.</p><p><strong>Methods: </strong>We analyzed 236,115 nights of home-based sleep data, collected over one year from 1,067 users of the SleepRoutine® mobile application in South Korea. Each night's data was paired with contemporaneous weather data from Seoul. Apnea-hypopnea index (AHI) values were classified on a nightly basis into low (< 15) and high (≥ 15) groups.</p><p><strong>Results: </strong>Elevated temperature was associated with decreased sleep efficiency (SE), total sleep time (TST), and deep sleep ratio (all p < 0.001), along with increased sleep latency (SL), and wake after sleep onset (WASO) (all p < 0.001). Higher humidity correlated with lower SE and light sleep ratio (p < 0.001, 0.004), and with longer WASO (p = 0.02, < 0.01). Longer sunshine duration was linked to greater TST, WASO, and REM sleep ratio (all p < 0.01) and to a decrease in sleep latency and light sleep ratio (p < 0.01). Relative to spring, summer demonstrated the poorest sleep quality, whereas autumn and winter showed variable effects. Importantly, temperature and sunshine duration demonstrated significant interactions with AHI group. In nights with higher AHI, weather-associated changes in SE, TST, and WASO were diminished. Seasonal interactions with AHI also significant across multiple sleep stages.</p><p><strong>Conclusions: </strong>Temperature, humidity, and sunshine duration were significantly associated with sleep structure. These effects may be less pronounced in individuals with sleep-disordered breathing.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"30 5","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149123889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}