Moritz T Winkelmann, Johann Jacoby, Chris Schwemmer, Sebastian Faby, Patrick Krumm, Christoph Artzner, Malte N Bongers
{"title":"Fully Automated Artery-Specific Calcium Scoring Based on Machine Learning in Low-Dose Computed Tomography Screening.","authors":"Moritz T Winkelmann, Johann Jacoby, Chris Schwemmer, Sebastian Faby, Patrick Krumm, Christoph Artzner, Malte N Bongers","doi":"10.1055/a-1717-2703","DOIUrl":"https://doi.org/10.1055/a-1717-2703","url":null,"abstract":"<p><strong>Purpose: </strong>Evaluation of machine learning-based fully automated artery-specific coronary artery calcium (CAC) scoring software, using semi-automated software as a reference.</p><p><strong>Methods: </strong>A total of 505 patients underwent non-contrast-enhanced calcium scoring computed tomography (CSCT). Automated, machine learning-based software quantified the Agatston score (AS), volume score (VS), and mass score (MS) of each coronary artery [right coronary artery (RCA), left main (LM), circumflex (CX) and left anterior descending (LAD)]. Identified CAC of readers who annotated the data with semi-automated software served as a reference standard. Statistics included comparisons of evaluation time, agreement of identified CAC, and comparisons of the AS, VS, and MS of the reference standard and the fully automated algorithm.</p><p><strong>Results: </strong>The machine learning-based software correlated strongly with the reference standard for the AS, VS, and MS (Spearman's rho > 0.969) (p < 0.001), with excellent agreement (ICC > 0.919) (p < 0.001). The mean assessment time of the reference standard was 59 seconds (IQR 39-140) and that of the automated algorithm was 5.9 seconds (IQR 3.9-16) (p < 0.001). The Bland-Altman plots mean difference and 1.96 upper and lower limits of agreement for all arteries combined were: AS 0.996 (1.33 to 0.74), VS 0.995 (1.40 to 0.71), and MS 0.995 (1.35 to 0.74). The mean bias was minimal: 0.964-1.0429. Risk class assignment showed high accuracy for the AS in total (weighed κ = 0.99) and for each individual artery (κ = 0.96-0.99) with corresponding correct risk group assignment in 497 of 505 patients (98.4 %).</p><p><strong>Conclusion: </strong>The fully automated artery-specific coronary calcium scoring algorithm is a time-saving procedure and shows excellent correlation and agreement compared with the clinically established semi-automated approach.</p><p><strong>Key points: </strong>· Very high correlation and agreement between fully automatic and semi-automatic calcium scoring software.. · Less time-consuming than conventional semi-automatic methods.. · Excellent tool for artery-specific calcium scoring in a clinical setting..</p><p><strong>Citation format: </strong>· Winkelmann MT, Jacoby J, Schwemmer C et al. Fully Automated Artery-Specific Calcium Scoring Based on Machine Learning in Low-Dose Computed Tomography Screening. Fortschr Röntgenstr 2022; 194: 763 - 770.</p>","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"763-770"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39860913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karolin Baumgartner, Wolfgang Bethge, Christian Philipp Reinert, Benjamin Bender, Konstantin Nikolaou, Marius Horger
{"title":"[Imaging findings of CAR-T cell therapy associated complications].","authors":"Karolin Baumgartner, Wolfgang Bethge, Christian Philipp Reinert, Benjamin Bender, Konstantin Nikolaou, Marius Horger","doi":"10.1055/a-1818-6705","DOIUrl":"https://doi.org/10.1055/a-1818-6705","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"699-704"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wilhelm-Conrad-Röntgen-Preis 2022 an den Radiologen PD Dr. Omar Dzaye von der Charité – Universitätsmedizin Berlin verliehen.","authors":"","doi":"10.1055/a-1844-4201","DOIUrl":"https://doi.org/10.1055/a-1844-4201","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"781-783"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kim Gehling, Theresa Mokry, Thuy Duong Do, Frederik Lars Giesel, Sascha Dietrich, Uwe Haberkorn, Hans-Ulrich Kauczor, Tim Frederik Weber
{"title":"Dual-Layer Spectral Detector CT in Comparison with FDG-PET/CT for the Assessment of Lymphoma Activity.","authors":"Kim Gehling, Theresa Mokry, Thuy Duong Do, Frederik Lars Giesel, Sascha Dietrich, Uwe Haberkorn, Hans-Ulrich Kauczor, Tim Frederik Weber","doi":"10.1055/a-1735-3477","DOIUrl":"https://doi.org/10.1055/a-1735-3477","url":null,"abstract":"<p><strong>Purpose: </strong>In patients with malignant lymphoma, disease activity is recommended to be assessed by FDG-PET/CT and the Deauville five-point scale (5-PS). The purpose of this study was to explore the potential of iodine concentration measured in contrast-enhanced dual-layer spectral detector CT (SDCT) as an alternative surrogate parameter for lymphoma disease activity by investigating its correlation with maximum standardized uptake values (SUV<sub>max</sub>) and 5-PS.</p><p><strong>Materials and methods: </strong>25 patients were retrospectively analyzed. Contrast-enhanced SDCT and FDG-PET/CT were performed in the same treatment interval within at most 3 months. CT attenuation values (AV), absolute iodine concentrations (aIC), and normalized iodine concentrations (nIC) of lymphoma lesions were correlated with SUV<sub>max</sub> using Spearman's rank correlation coefficient. The performance of aIC and nIC to detect lymphoma activity (defined as 5-PS > 3) was determined using ROC curves.</p><p><strong>Results: </strong>60 lesions were analyzed, and 31 lesions were considered active. AV, aIC, and nIC all correlated significantly with SUV<sub>max</sub>. The strongest correlation (Spearman ρ = 0.71; p < 0.001) and highest area under the ROC curve (AUROC) for detecting lymphoma activity were observed for nIC normalized to inferior vena cava enhancement (AUROC = 0.866). The latter provided sensitivity, specificity, and diagnostic accuracy of 87 %, 75 %, and 80 %, respectively, at a threshold of 0.20. ROC analysis for AV (AUROC = 0.834) and aIC (AUROC = 0.853) yielded similar results.</p><p><strong>Conclusion: </strong>In malignant lymphomas, there is a significant correlation between metabolic activity as assessed by FDG-PET/CT and iodine concentration as assessed by SDCT. Iodine concentration shows promising diagnostic performance for detecting lymphoma activity and may represent a potential imaging biomarker.</p><p><strong>Key points: </strong>· Iodine concentration correlates significantly with SUVmax in lymphoma patients. · Iodine concentration may represent a potential imaging biomarker for detecting lymphoma activity. · Normalization of iodine concentration improves diagnostic performance of iodine concentration.</p><p><strong>Citation format: </strong>· Gehling K, Mokry T, Do TD et al. Dual-Layer Spectral Detector CT in Comparison with FDG-PET/CT for the Assessment of Lymphoma Activity. Fortschr Röntgenstr 2022; 194: 747 - 754.</p>","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"747-754"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39835171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Okka Wilkea Hamer, Jürgen Biederer, Marco Das, Hans-Ulrich Kauczor, Mark Oliver Wielpütz, Julia Ley-Zaporozhan, Jens Vogel-Claussen, Dag Wormanns, Sebastian Ley
{"title":"[Comment on: Notification of revised diagnostic reference levels for diagnostic and interventional X-Ray Procedures by the Bundesamt für Strahlenschutz].","authors":"Okka Wilkea Hamer, Jürgen Biederer, Marco Das, Hans-Ulrich Kauczor, Mark Oliver Wielpütz, Julia Ley-Zaporozhan, Jens Vogel-Claussen, Dag Wormanns, Sebastian Ley","doi":"10.1055/a-1813-3116","DOIUrl":"https://doi.org/10.1055/a-1813-3116","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"717-719"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Comment from Blum et al. on Structured Reporting of Whole-Body Trauma CT scans: Friend, not Foe.","authors":"Lena-Marie Dendl, Andreas G Schreyer","doi":"10.1055/a-1847-4837","DOIUrl":"https://doi.org/10.1055/a-1847-4837","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"778-779"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph Georg Radosa, Jonathan Nadjiri, Andreas H Mahnken, Arno Bücker, Lothar J Heuser, Dominik Morhard, Peter Landwehr, Ansgar Berlis, Marcus Katoh, Peter Reimer, Balthasar Schachtner, Michael Ingrisch, Philipp Paprottka, Ralf-Thorsten Hoffmann
{"title":"Availability of Interventional Oncology in Germany in the Years 2018 and 2019 - Results from a Nationwide Database (DeGIR Registry Data).","authors":"Christoph Georg Radosa, Jonathan Nadjiri, Andreas H Mahnken, Arno Bücker, Lothar J Heuser, Dominik Morhard, Peter Landwehr, Ansgar Berlis, Marcus Katoh, Peter Reimer, Balthasar Schachtner, Michael Ingrisch, Philipp Paprottka, Ralf-Thorsten Hoffmann","doi":"10.1055/a-1729-0951","DOIUrl":"https://doi.org/10.1055/a-1729-0951","url":null,"abstract":"<p><strong>Objective: </strong>Over the past few decades, radiology has established itself in tumor therapy through interventional oncology including innovative and efficient procedures for minimalinvasive treatment of various tumor entities besides the \"classic\" therapeutic options such as surgery, chemotherapy and radiotherapy.Aim of this study was to evaluate the extent to which interventional oncology can provide nationwide care using the data from the register of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR registry), which records radiological interventions as part of quality assurance.</p><p><strong>Methods: </strong>The numbers of interventions of participating clinics, which were recorded as part of module D (oncological procedures including TACE or other tumor-specific embolization, ablation, percutaneous tumor therapy) and identified by the DeGIR registry between 2018 and 2019, were analyzed retrospectively. The collected intervention data were evaluated regarding federal states and 40 smaller regions (administrative districts and former administrative districts).</p><p><strong>Results: </strong>In 2018, 11 653 oncological interventions in 187 clinics were recorded by the DeGIR registry. In 2019, the number of participating clinics rose to 216 and the number of oncological interventions increased by 6 % to 12 323. The average number of oncological interventions per clinic decreased slightly from 62.5 (2018) to 57.1 (2019). The DeGIR requirement for being certified as a training center was met by 116 clinics in 2018 including 31 clinics with more than 100 interventions and 129 clinics in 2019 including 36 with more than 100 interventions. Oncological interventions have been performed in each of the 40 regions. An average of 599 interventions per region (standard deviation of 414) was recorded in the period between 2018 and 2019.</p><p><strong>Conclusion: </strong>Based on the distribution of the documented oncological interventions at federal state level as well as the district level, the supply of interventional tumor therapy depends on the geographical location. Therefore, the demand of oncological interventions might not be sufficiently covered in some regions.</p><p><strong>Key points: </strong>· Interventional-oncological tumor therapies are performed throughout Germany. · Looking at the notable geographical differences, the need for interventional oncological procedures does not seem to be sufficiently met.. · In order to improve the comprehensive provision of oncological interventions, the training of interventional radiologists should be promoted further..</p><p><strong>Citation format: </strong>· Radosa CG, Nadjiri J, Mahnken AH et al. Availability of Interventional Oncology in Germany in the Years 2018 and 2019 - Results from a Nationwide Database (DeGIR Registry Data). Fortschr Röntgenstr 2022; 194: 755 - 761.</p>","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"755-761"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39835170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"„Mit der Weiterentwicklung der Zertifizierung unter dem Dach der DeGIR stellen wir die Weichen für eine positive Zukunft der Interventionellen Radiologie“.","authors":"","doi":"10.1055/a-1844-4091","DOIUrl":"https://doi.org/10.1055/a-1844-4091","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"787-789"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sophia Freya Ulrike Blum, Maria Eberlein-Gonska, Ralf-Thorsten Hoffmann
{"title":"Structured Reporting of Whole-Body Trauma CT Scans: Friend, not Foe.","authors":"Sophia Freya Ulrike Blum, Maria Eberlein-Gonska, Ralf-Thorsten Hoffmann","doi":"10.1055/a-1847-4069","DOIUrl":"https://doi.org/10.1055/a-1847-4069","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"777-778"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Teil 1: Auf der Suche nach einem dreidimensionalen Bild des Gehirns von Dr. Uwe Busch, Deutsches Röntgen-Museum, Remscheid.","authors":"","doi":"10.1055/a-1844-3990","DOIUrl":"https://doi.org/10.1055/a-1844-3990","url":null,"abstract":"","PeriodicalId":520772,"journal":{"name":"RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin","volume":" ","pages":"785-787"},"PeriodicalIF":1.8,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}