{"title":"[Diagnosis and treatment of opportunistic infections in HIV/AIDS adult patients].","authors":"Martín Lasso B","doi":"/S0716-10182011000600010","DOIUrl":"https://doi.org//S0716-10182011000600010","url":null,"abstract":"<p><p>The following guidelines for the diagnosis and treatment of opportunistic infections (OI) in adult HIV/AIDS patients represent the first approach to standardize the management of this patient group in Chile. The guidelines are based on scientific evidence. They intend to serve as a practical and easy-to-use tool for physicians during the process of selecting appropriate diagnostic tests and effective treatments for their patients. They also include the local experience in Chile related to OI in HIV/AIDS patients. Regular up-dates to include new scientific knowledge are proposed.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"440-60"},"PeriodicalIF":0.5,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40127610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudio Alburquenque O, Viviana Silva A, Milenko Fuentes G, Cecilia Tapia C, Víctor Silva V
{"title":"[In vitro andulafungin susceptibility of 100 of Candida strains obtained previously to the introduction of this echinocandin in Chile].","authors":"Claudio Alburquenque O, Viviana Silva A, Milenko Fuentes G, Cecilia Tapia C, Víctor Silva V","doi":"/S0716-10182011000600001","DOIUrl":"https://doi.org//S0716-10182011000600001","url":null,"abstract":"<p><p>Fungi, particularly yeasts, have become important opportunistic pathogens that can be resistant to antifungal agents or develop resistance. To address this problem, new molecules such as echinocandins, have been developed. Susceptibility to anidulafungin was studied in yeasts isolated previous to the introduction of this drug in Chile. One hundred strains of different yeast species isolated from invasive fungal infections during 2007 and 2008 were studied. Susceptibility testing of anidulafungin was performed by broth microdilution according to CLSI. All strains were susceptible to anidulafungin. MIC50 and MIC90 were 0.125 µg/mL and 1 µg/mL, respectively. Compared to other yeasts, C. parapsilosis showed a slight increase in the MICs for anidulafungin (MIC50, 1 µg/mL, MIC90, 2 µg/mL), but remained within the susceptible range. Both, fluconazole resistant (8) and dose dependent susceptible strains (16) were susceptible to anidulafungin. In vitro, this echinocandin appears to be an effective therapeutic alternative.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"399-403"},"PeriodicalIF":0.5,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40127603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Weeksella virosa].","authors":"María A Martínez T, Alfredo Ovalle S","doi":"/S0716-10182011000600007","DOIUrl":"https://doi.org//S0716-10182011000600007","url":null,"abstract":"","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"429-30"},"PeriodicalIF":0.5,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40127607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antiretroviral resistance in human immunodeficiency virus infection].","authors":"Alejandro Afani S, Ana M Gallardo O","doi":"/S0716-10182011000600011","DOIUrl":"https://doi.org//S0716-10182011000600011","url":null,"abstract":"<p><p>Resistance to anti-retroviral therapy is one of the main problems in the favorable outcome of treatment in HIV patients, as well as toxicity and adherence to treatment. Resistance has increased in recent years, and it is evaluated through genotyping and phenotypic tests. Information provided by these studies is crucial when deciding the most appropriate treatment. However, genotype interpretation is complex and subject to frequent change, because of the incorporation of new drugs and the appearance of new resistance patterns. This review aims ,understanding the fundamental concepts of antiretroviral resistance (ARV), which examines the general principles, mechanisms and patterns of resistance, both for the traditional family of anti-retrovirals, as well as for the most recently licensed drugs.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"461-9"},"PeriodicalIF":0.5,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40127611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Dr. Pedro Morán, the medical school of 1833, and the battle of Rancagua].","authors":"Enrique Laval R","doi":"/S0716-10182011000600015","DOIUrl":"https://doi.org//S0716-10182011000600015","url":null,"abstract":"<p><p>With the foundation of the Medical School of 1833, the figure of Pedro Moran, the first professor of anatomy, physiology and hygiene, stands out. Diverse comments of his acts are recounted, some praising him and others revealing his concealment during the heat of the battle. His humble origins, competence and perseverance in the fulfillment of the teaching duties are extolled.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"484-7"},"PeriodicalIF":0.5,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40127567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Moses Maimonides, \"physician of princes, prince of physicians\"].","authors":"Jaime Cerda L","doi":"/S0716-10182009000500013","DOIUrl":"https://doi.org//S0716-10182009000500013","url":null,"abstract":"<p><p>Moses Maimonides (1135-1204) is considered the most prominent figure of Judaism during the Middle Ages. Born within the Sephardic Jewish community of Cordoba, his rich intellectual education (theological, philosophical and medical) together with a deep spirituality gave birth to the figure of a highly humanitarian, rational and dedicated physician. His medical legacy includes ten treatises, among them 'Medical Aphorisms of Moses', a set of 1,500 aphorisms organized in 25 chapters, each dealing with a different area of medicine. His theological works and the renowned 'Guide for the Perplexed' raised his figure as a theologist and modern philosopher, being the latest his most universal creation. His life and legacy are an invitation to raise the medical vocation and practice beyond a simple occupation.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"370-3"},"PeriodicalIF":0.5,"publicationDate":"2009-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40054853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anamaría Peña D, Tamara Viviani S, Nicole Le Corre P, Viera Morales M, Constanza Montecinos B, Cristina Gajardo S
{"title":"[Treatment of urinary tract infections in febrile infants: experience of outpatient intravenous antibiotic treatment].","authors":"Anamaría Peña D, Tamara Viviani S, Nicole Le Corre P, Viera Morales M, Constanza Montecinos B, Cristina Gajardo S","doi":"/S0716-10182009000500008","DOIUrl":"https://doi.org//S0716-10182009000500008","url":null,"abstract":"<p><strong>Objective: </strong>To describe the feasibility, effectiveness and safety of intravenous (iv) outpatient treatment in 2 to 24 month-old children with febrile urinary tract infection (UTI).</p><p><strong>Method: </strong>Children presenting to the ER, between April 2003-2005, with fever and no identifiable focus who had a diagnosis of UTI were randomized to receive iv antibiotic in the hospital or in an outpatient facility. Children were started on amikacin or ceftriaxona according to physician criteria followed by antimicrobial adjustment based on urine culture result and a later switch to an oral antimicrobial. Urine cultures were performed during and after completing the antimicrobial course. Adherence and effectiveness of antimicrobial treatment and treatment-associated complications were analyzed.</p><p><strong>Results: </strong>The study included 112 patients, 58 inpatient children and 54 outpatient children, with an average age of 7.7 months. Duration of iv treatment did not differ among groups (2.8 days (SD 1.2) 2.7 +0.91 days in inpatients vs 2.9 + 1.9 days in outpatients (p = 0.22). In 100% of outpatient children and 100% of inpatient children (overall 101/101) urine cultures were negative on day 5. None of the children had a treatment-associated complication. Cost analysis yielded 73% of saving money (overall cost for inpatient treatment US 9,815 vs outpatient treatment US 2,650).</p><p><strong>Conclusions: </strong>Outpatient iv treatment in patients between 2 and 24 months with UTI and fever was effective, safe and of lower cost.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"350-4"},"PeriodicalIF":0.5,"publicationDate":"2009-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40054873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hafnia alvei].","authors":"Claudia Moreno M","doi":"/S0716-10182009000500009","DOIUrl":"https://doi.org//S0716-10182009000500009","url":null,"abstract":"","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"355"},"PeriodicalIF":0.5,"publicationDate":"2009-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40054874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisca Schroeder H, Andrea Elgueta N, M José Martínez G
{"title":"[Eczema herpeticum caused by herpes simplex virus type 2. Review of the literature about one case].","authors":"Francisca Schroeder H, Andrea Elgueta N, M José Martínez G","doi":"/S0716-10182009000500010","DOIUrl":"https://doi.org//S0716-10182009000500010","url":null,"abstract":"<p><p>Eczema herpeticum is an extensive vesicular eruption caused by cutaneous dissemination of herpes simplex virus in patients who have underlying skin conditions or epidermal barrier disruption. Herpes simplex virus type 1 (HSV 1) is the most common etiology. This is the first report in Chile of a case of eczema herpeticum caused by HSV 2 in a patient with Darier's disease, We review the literature and emphasize the use of sensitive and specific assays as real time polymerase chain reaction, that allow to initiate timely the correct treatment.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"356-9"},"PeriodicalIF":0.5,"publicationDate":"2009-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40054850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Thermic stairways theory].","authors":"Marco Aurelio Macchiavello C","doi":"/S0716-10182009000500015","DOIUrl":"https://doi.org//S0716-10182009000500015","url":null,"abstract":"<p><p>In this article we raise the possibility of a potential relationship between body temperature of different species of animals and the Avian Flu. We hypothesize that the different values of body temperature could act as an enabling mechanism for Influenza virus infection through an adaptative mechanism of the virions in the species susceptible to infection, including human beings.</p>","PeriodicalId":520768,"journal":{"name":"Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia","volume":" ","pages":"376-7"},"PeriodicalIF":0.5,"publicationDate":"2009-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40054855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}