Otolaryngologia polska = The Polish otolaryngology最新文献

{"title":"The impact of COVID-19 on the clinical course of acute mastoiditis - analysis of children hospitalized in the University Department in years 2018-2022.","authors":"Maria Wolniewicz, Lidia Zawadzka-Głos, Jolanta Jadczyszyn","doi":"10.5604/01.3001.0055.1235","DOIUrl":"https://doi.org/10.5604/01.3001.0055.1235","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Serious intracranial complications of acute mastoiditis seem to be reduced due to vaccine prophylaxis and antibiotics, but recently, after the COVID-19 era, we observe its significant growth.&lt;b&gt;Aim:&lt;/b&gt; Due to this observed growth, especially regarding central venous thrombosis, we decided to investigate the patterns of infections within our patients.&lt;b&gt;Materials and methods:&lt;/b&gt; We retrospectively analyzed patients hospitalized in our clinic in the years 2018-2022 with the diagnosis of acute mastoiditis. We gathered and analyzed data concerning patients' characteristics and the course of illness. We divided our data into 2 groups: pre- and post-COVID-19-era cases.&lt;b&gt;Results:&lt;/b&gt; We found 97 records of 86 patients treated due to acute mastoiditis. As many as 54 cases were classified as pre- and 43 as post-COVID-19 cases. We noted a definite decline in hospitalizations from March 2020 to September 2021 (to 0), which reflects the lockdown period. In the year 2022 we had surprisingly more cases in spring and summer months than in winter. We observed male predominance (p&gt;0.5). Most cases in the pre-COVID group received no treatment before hospitalization in our clinic (p&lt;0.05). We observed higher WBC and CRP levels in the post-COVID group (p&lt;0.05). We found no statistically significant differences in microbiological results between the groups. We found more serious complications in the post-COVID group, with statistical significance only for nerve abducens palsy. We observed a higher need for the use of Vancomycin alone (p = 0.04), mostly as a corrected treatment, or in combination with Ceftriaxone (p = 0.04) in the post-COVID group. The mean time of hospitalization between the 2 groups seems to be similar and was about 13 4 days.&lt;b&gt;Conclusions:&lt;/b&gt; We presume that the children's isolation, together with post-infection immunosuppression led to the observed growth of severe complications.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 4","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic mutations in recurrent and/or metastatic nasopharyngeal carcinoma - an analysis of the Japanese national genomic profiling database.","authors":"Hiromi Nagano, Hayato Matsumoto, Yumi Ando, Koji Takumi, Masatoyo Nakajo, Masaru Yamashita","doi":"10.5604/01.3001.0055.1903","DOIUrl":"10.5604/01.3001.0055.1903","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Although genetic mutations have been reported in nasopharyngeal carcinoma (NPC), there are currently no scientifically validated treatments targeting these mutations. Furthermore, cancer genomic profiling tests are underutilized in clinical practice. This highlights an urgent need to explore the genomic landscape of NPC and its potential therapeutic implications.&lt;b&gt;Aim:&lt;/b&gt; The aim of this study is to investigate the genetic mutational landscape of recurrent and/or metastatic nasopharyngeal carcinoma (NPC).&lt;b&gt;Materials and methods:&lt;/b&gt; Data were analyzed for 67 consecutive patients with NPC registered at the Japan National Cancer Center, Center for Cancer Genomics and Advanced Therapeutics (C-CAT) between June 2019 and May 2024. Genetic mutations were determined by FoundationOne CDx or Liquid CDx next-generation sequencing. Survival of patients was determined by the log-rank test and a Cox proportional hazards model.&lt;b&gt;Results:&lt;/b&gt; The top 10 mutations in NPC were &lt;i&gt;CDKN2A&lt;/i&gt; (41.8%), &lt;i&gt;CDKN2B&lt;/i&gt; (31.3%), &lt;i&gt;TP53&lt;/i&gt; (20.9%), &lt;i&gt;KMT2D&lt;/i&gt; (20.9%), &lt;i&gt;DNMT3A&lt;/i&gt; (19.4%), &lt;i&gt;NOTCH1&lt;/i&gt; (17.9%), &lt;i&gt;STK11&lt;/i&gt; (17.9%), &lt;i&gt;MTAP&lt;/i&gt; (17.9%), &lt;i&gt;EP300&lt;/i&gt; (17.9%), &lt;i&gt;TSC1&lt;/i&gt; (13.4%), with 11.1 6.1 (mean SEM) mutations/individual. Mutations in &lt;i&gt;KMT2D&lt;/i&gt; (p = 0.0127), &lt;I&gt;DNMT3A&lt;/i&gt; (p = 1.41×10&lt;sup&gt;-7&lt;/sup&gt;), &lt;i&gt;GNAS&lt;/i&gt; (p = 3.64×10&lt;sup&gt;-11&lt;/sup&gt;), &lt;i&gt;SPEN&lt;/i&gt; (p = 0.0167), &lt;i&gt;BRCA1&lt;/i&gt; (p = 0.0379), and &lt;i&gt;KMT2A&lt;/i&gt; (p = 2.06×10&lt;sup&gt;-5&lt;/sup&gt;) were associated with a significantly worse prognosis, as determined by the log-rank test. The hazard ratios for cases with these mutations were 0.0122 (95% CI, 1.58×10&lt;sup&gt;-4&lt;/sup&gt;-0.936, p = 0.046) for &lt;i&gt;TP53&lt;/i&gt;, 1847.0 (95% CI, 4.619-7.386×10&lt;sup&gt;5&lt;/sup&gt;, p = 0.014) for &lt;i&gt;DNMT3A&lt;/i&gt;, 126.7 (95% CI, 1.262-12720, p = 0.039) for &lt;i&gt;BRCA2&lt;/i&gt;, 197.9 (95% CI, 2.844-13770, p = 0.015) for &lt;i&gt;ALK&lt;/i&gt;, 34.22 (95% CI, 1.256-932.7, p = 0.036) for &lt;i&gt;SPEN&lt;/i&gt;, and 6.445×10&lt;sup&gt;-4&lt;/sup&gt; (95% CI, 2.913×10&lt;sup&gt;-6&lt;/sup&gt;-0.143, p = 7.6×10&lt;sup&gt;-3&lt;/sup&gt;) for &lt;i&gt;MYCL&lt;/i&gt;.&lt;b&gt;Conclusions:&lt;/b&gt; This study identified genetic mutations in recurrent and/or metastatic NPC. Even in advanced cases, prognosis-related mutations were identified, underscoring the importance of cancer genomic profiling tests.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 4","pages":"34-39"},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"15th Congress of the European Laryngological Society, May 2025, Warsaw, Poland.","authors":"Małgorzata Wierzbicka","doi":"10.5604/01.3001.0055.1485","DOIUrl":"10.5604/01.3001.0055.1485","url":null,"abstract":"<p><p>The 15th Congress of the European Laryngological Society, held on 8-10 May 2025 in Warsaw, Poland, brought together leading specialists in laryngology, phoniatrics, airway surgery, neurolaryngology and related disciplines. Hosted at the Hilton Warsaw City, the congress provided an extensive platform for scientific exchange, presentation of new research, and discussion of clinical innovations. The scientific programme encompassed keynote lectures, symposia, round tables, instructional courses, free paper sessions and e-poster presentations. Key thematic areas included laryngeal cancer, airway disorders, voice and phoniatrics, swallowing dysfunction, reflux-related conditions, and the rapidly developing field of artificial intelligence in laryngology. The congress proceedings were prepared in collaboration with the &lt;i&gt;Polish Journal of Otolaryngology - Otolaryngologia Polska&lt;/i&gt;, supporting the dissemination of the scientific output presented during the meeting. The 15th ELS Congress served as an important forum for presenting original research and strengthening international collaboration within the global laryngology community, offering participants a dynamic environment to exchange expertise and contribute to the advancement of contemporary laryngological practice.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 0","pages":"1-91"},"PeriodicalIF":0.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145703480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ideal facial relationships and goals - are they still useful in preoperative analysis before rhinoplasty?","authors":"Piotr Rot, Sandra Krzywdzińska, Aleksander Markiewicz, Maria Sobol, Adam Turczynowicz, Dariusz Jurkiewicz, Marcin Jadczak","doi":"10.5604/01.3001.0055.1329","DOIUrl":"https://doi.org/10.5604/01.3001.0055.1329","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Facial analysis is a critical component of plastic surgery. When planning a rhinoplasty procedure, a patient&apos;s current facial proportions, along with factors such as race, ethnicity, age and gender, must be considered. Achieving an ideal facial balance requires positioning these factors harmoniously for each unique patient.&lt;b&gt;Aim:&lt;/b&gt; The aim of this study is to explore the impact of external nasal reshapingfollowing rhinoplasty on facial proportions, aligning them more closely withnormative values.&lt;b&gt;Material and methods:&lt;/b&gt; A photographic analysis was conducted on images taken before surgery and six months postoperatively. Measurements were made using a semi-automated method, where facial topographic points were selected and angles and proportions were automatically calculated and compared to normative data. The study included 93 patients (76 women and 17 men) who underwent rhinoplasty. For each patient, the following parameters were assessed before and after surgery: nasofrontal, nasomental, legan facial convexity, nasolabial, nasofacial, mentocervical angles, Goode ratio, facial height ratios, nasal index and various nasal to facial proportions.&lt;b&gt;Results:&lt;/b&gt; In female patients, rhinoplasty resulted in a significant decrease in nasofrontal angle, Legan facial convexity, undernose face ratio and intercanthal to nasal breadth ratio, while nasomental angle, lower facial height ratio and nasal index showed a significant increase. In male patients, significant changes were observed in Legan facial convexity, lower facial height ratio, undernose face ratio and intercanthal to nasal breadth ratio, all of which decreased postoperatively&lt;b&gt;Conclusions:&lt;/b&gt; The key angles are essential for determining the ideal nasal position and must be carefully considered in preoperative evaluations. While traditional facial proportions are useful, they should be applied flexibly, considering each patient&apos;s unique features and aesthetic goals. The future of rhinoplasty combines these principles with personalized approaches that respect diverse beauty standards.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 4","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term acoustic outcomes, perceptual voice assessment and voice-related quality of life in transgender women undergoing Wendler glottoplasty: a single-center experience.","authors":"Marta Rogalska, Maciej Zieliński, Anna Kasperczuk, Łukasz Antkowiak, Marta Gamrot-Wrzoł, Maciej Misiołek","doi":"10.5604/01.3001.0055.1327","DOIUrl":"https://doi.org/10.5604/01.3001.0055.1327","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Since the voice is uniquely tied to gender identity, it constitutes a considerable factor in the transition process of transgender individuals. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; We aimed to analyze the long-term durability of Wendler glottoplasty (WG) acoustic outcomes in transgender women and juxtapose the objective results with voice-related quality of life (QoL) assessment and gender perception in telephone communication. &lt;br&gt;&lt;br&gt;&lt;b&gt;Methods:&lt;/b&gt; We retrospectively reviewed the records of 7 transgender women who underwent WG, self-assessed their voice-related QoL, and participated in the telephone test. Long-term results were compared with data acquired preoperatively and at short-term follow-up, as well as with the age-matched control group of 7 cisgender males and 7 cisgender females. The speech samples of transfeminine individuals and cisgender controls were judged by 64 cisgender listeners. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; After an average of 18.63 months, a persistent, significant increase in fundamental frequency, speaking fundamental frequency, and lower limit of the frequency range of spoken voice was observed, with the values being comparable to cisgender female controls. Despite a significant long-term improvement in the emotional domain of the Voice Handicap Index, the remaining voice-related QoL scores deteriorated compared to the short-term evaluation. The gender of transfeminine individuals was significantly more often incorrectly attributed compared to cisgender controls. The percentage of voice ratings as a female was not correlated with the acoustic measures, self-assessed vocal femininity, and satisfaction with WG results. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Despite the long-term durability of acoustic changes after WG, the gradual reduction of the initially improved voice-related QoL suggests the need for multidisciplinary management. The acoustic measures cannot guarantee voice attribution as female by external evaluators, indicating the beneficial role of perceptual assessment in analyzing WG outcomes.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 4","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Vitamin D Deficiency a Cause of Refractory Benign Paroxysmal Positional Vertigo (BPPV)?","authors":"Dastan Temirbekov, Elif Sari","doi":"10.5604/01.3001.0055.0939","DOIUrl":"https://doi.org/10.5604/01.3001.0055.0939","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Vitamin D is crucial for calcium metabolism, and its role in benign paroxysmal positional vertigo (BPPV) pathogenesis has been increasingly recognized. However, its impact on treatment resistance in BPPV patients remains unclear and understudied.&lt;b&gt;Aim:&lt;/b&gt; This study investigated the association between treatment resistance in BPPV and various risk factors, including vitamin D deficiency, age, gender, and comorbidities.&lt;b&gt;Materials and methods:&lt;/b&gt; A retrospective review of medical records was conductedon 122 patients diagnosed with BPPV at a tertiary care hospital between January2020 and January 2023. The diagnosis of BPPV was confirmed using clinical historyand positional tests, while serum 25-OH vitamin D levels were measured usingchemiluminescence immunoassay. Patients who required three or more canalithrepositioning maneuvers were considered treatment-resistant. Logistic regressionanalysis was employed to assess the impact of demographic and clinical factors onBPPV treatment resistance, and recurrence rates were evaluated over a one-yearfollow-up period.&lt;b&gt;Results:&lt;/b&gt; Logistic regression revealed that male gender, comorbidities, and betahistine use were significantly associated with BPPV resistance (p &lt; 0.05), while no significant relationship was found between vitamin D levels and treatment resistance or recurrence (p &gt; 0.05). Recurrence was observed in 22.1% of patients during the follow- -up period, though this was not significantly related to vitamin D status.&lt;b&gt;Conclusions:&lt;/b&gt; While previous studies suggested a potential link between vitamin Ddeficiency and BPPV recurrence, this study found no significant association betweenvitamin D deficiency and resistance along with the recurrence of BPPV. Instead, malegender, comorbidities (notably hypertension), and betahistine use were identified asrisk factors for requiring multiple maneuvers. The study raises questions about therole of vitamin D in BPPV pathophysiology and suggests that other clinical factorsmay have a greater influence on treatment outcomes.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 3","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination therapy in the treatment of acute rhinosinusitis, including intranasal glucocorticosteroids and phytotherapy.","authors":"Paweł Papież","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acute sinusitis (AS) is a rapid-onset inflammation of the nasal mucosa andparanasal sinuses. In about 98-99% of cases, AS is caused by viral infections,most commonly by rhinoviruses, coronaviruses, parainfluenza viruses, influenzaviruses, and adenoviruses. Bacterial superinfections occur in only about 1% ofviral infections. The widespread overuse of antibiotics for this usually self-limitingdisease has contributed significantly to the global problem of antibiotic resistance.Accordingly, treatment guidelines strongly promote symptomatic treatmentand therapies that target the underlying inflammation and pathophysiology.This review examines the evidence for the efficacy of two classes of drugs asrecommended in the EPOS 2020 guidelines: intranasal corticosteroids (INCS) andthe plant-based medicinal product BNO 1016. The analysis encompassed different mechanisms of action of both agents, high-quality clinical evidence supporting their efficacy and safety, and the benefitsof combination therapy using both drugs. An analysis and comparison were made of the roles of both agents in moderntherapeutic strategies in AS. While INCS offer potent, targeted anti-inflammatory activity, BNO 1016 offers a multimodalapproach by combining secretolytic, anti-inflammatory, and antimicrobial properties. Both agents are key evidence--based alternatives to antibiotics to be used in line with the principles of responsible antibiotic therapy.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"79 5","pages":"58-64"},"PeriodicalIF":0.6,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in the course of the externalbranch of the superior laryngeal nerveand their importance in surgicalprocedures: an experimental cadaveric study.","authors":"Gkionoul Nteli Chatzioglou, Elif Sari, Özcan Gayretli, Osman Coşkun, Adnan Öztürk, İlke Ali Gürses","doi":"10.5604/01.3001.0016.2167","DOIUrl":"https://doi.org/10.5604/01.3001.0016.2167","url":null,"abstract":"<p><p>&lt;br&gt;&lt;b&gt;Introduction:&lt;/b&gt; Injury of the external branch of the superior laryngeal nerve can cause a hoarse or weak voice due to the functional loss (dysergia) of the cricothyroid muscle. Defining the anatomical variations of the external branch of the superior laryngeal nerve and estimating their frequency are crucial for surgical interventions.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; To reveal the topography of the external branch in the Anatolian population, to prevent injury of it during the surgical intervention in the anterior neck region.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Material and methods:&lt;/b&gt; 26 bilateral hemilarynges (4 females, 22 males) were dissected. The morphometric and morphological features of the external branch were examined. The obtained results were compared statistically, left and right.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Landmarks such as the thyroid gland and laryngeal prominence were determined for the detection of the external branch. The variations of the course of the external branch and the points of piercing the cricothyroid muscle or inferior pharyngeal constrictor muscle were evaluated.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Discussion:&lt;/b&gt; Although safe approaches have been described for nerve protection during neck surgeries, injuries may occur during preliminary surgery as the mentioned nerve is thinner and more superficial than other branches of the vagus nerve. However, it can be detected more easily and safely by knowing the defined anatomical landmarks and morphological variations of the external branch.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Conclusion:&lt;/b&gt; The anatomical variations described can be a safe and important guide in surgeries of the anterior neck region.&lt;/br&gt.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":"77 2","pages":"24-29"},"PeriodicalIF":0.6,"publicationDate":"2023-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoluminal larynx anatomy model - towards facilitating deep learning and defining standards for medical images evaluation with artificial intelligence algorithms.","authors":"Piotr Nogal,&nbsp;Mikołaj Buchwald,&nbsp;Michalina Staśkiewicz,&nbsp;Szymon Kupiński,&nbsp;Juliusz Pukacki,&nbsp;Cezary Mazurek,&nbsp;Joanna Jackowska,&nbsp;Małgorzata Wierzbicka","doi":"10.5604/01.3001.0015.9501","DOIUrl":"https://doi.org/10.5604/01.3001.0015.9501","url":null,"abstract":"<p><p>The pioneering nature of this work covers the answers to two questions: (1) Is an up-to-date anatomical model of the larynx needed for modern endoscopic diagnostics, and (2) can such a digital segmentation model be utilized for deep learning purposes. The idea presented in this article has never been proposed before, and this is a breakthrough in numerical approaches to aerodigestive videoendoscopy imaging. The approach described in this article assumes defining a process for data acquisition, integration, and segmentation (labeling), for the needs of a new branch of knowledge: digital medicine and digital diagnosis support expert systems. The first and crucial step of such a process is creating a digital model of the larynx, which has to be then validated utilizing multiple clinical, as well as technical metrics. The model will form the basis for further artificial intelligence (AI) requirements, and it may also contribute to the development of translational medicine.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":" ","pages":"1-9"},"PeriodicalIF":0.6,"publicationDate":"2022-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40568279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Juvenile angiofibroma: the value of CT and MRI for treatment planning and follow-up].","authors":"Anna Szymańska,&nbsp;Wiesław Gołabek,&nbsp;Henryk Siwiec,&nbsp;Radosław Pietura,&nbsp;Małgorzata Szczerbo-Trojanowska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Juvenile angiofibroma is a rare, benign, hypervascular, nasopharyngeal tumour. The aim of the study was to assess the value of CT and MR in determining therapeutic approach and follow-up in patients with this condition. There were 40 patients with juvenile angiofibroma. All patients underwent angiography. In 24 patients CT and 5 patients MRI was performed. Most patients (67%) presented with tumour stage III according to Chandler. Preoperative tumour staging based on CT was in accordance with surgical evaluation in 92% of cases. In 4 (17%) of 24 patients CT and MRI showed a recurrence after surgery. On the bases of radiological findings 2 patients were referred to irradiation instead of surgery. CT allows correct tumour staging in 92% of patients. It well demonstrates the presence and extension of the recurrence.</p>","PeriodicalId":520738,"journal":{"name":"Otolaryngologia polska = The Polish otolaryngology","volume":" ","pages":"85-90"},"PeriodicalIF":0.6,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40931032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}