{"title":"Delirium. A comprehensive review.","authors":"Hussein A Algahtani, Abduljaleel P Abdu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Delirium is among the most common potentially preventable neurological disorders encountered in diverse patient populations, especially in critical care units and the elderly. It may present with highly variable clinical features, prolong hospital stay, and herald a poor prognosis. It is also a source of distress for patients and their caregivers. A high degree of clinical suspicion is required for detecting delirium and a detailed history, physical examination, and targeted investigations are necessary to determine the underlying etiology and ensure proper management. The following article is a comprehensive review outlining the various aspects of delirium.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"205-12"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An ictal epilepsy case monitored by resting-state fMRI.","authors":"Peng-Fei Qiao, Guang-Ming Niu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Most resting-state functional MRI studies of epilepsy are conducted in the interictal phase as the ictal phase is not suitable. We report and discuss a 13-year-old female epilepsy patient who had ictal examination. She was diagnosed with simple partial seizure epilepsy and on regular anti-epileptic drugs. There were no significant symptoms after careful treatment. We conclude that analysis of the amplitude of low frequency fluctuations may provide a useful tool in the functional MRI study of epilepsy.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"256-8"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad J Golalipour, Maliheh Sedehi, Mostafa Qorbani
{"title":"Does maternal Helicobacter pylori infection increase the risk of occurrence of neural tube defects in newborns in Northern Iran?","authors":"Mohammad J Golalipour, Maliheh Sedehi, Mostafa Qorbani","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To determine the relation between maternal Helicobacter pylori (H. pylori) infection and the occurrence of neural tube defects (NTDs) in newborns.</p><p><strong>Methods: </strong>This hospital-based case-control study was carried out in Dezyani Teaching Hospital, Gorgan, Northern Iran from April 2007 to March 2009. Thirty-five mothers with NTD-affected newborns, and 53 mothers with healthy newborns were considered the cases and controls. A peripheral blood sample was obtained from all subjects, and H. pylori infections were tested by H. pylori serum antibody. The serum folic acid, vitamin B12, ferritin, and homocysteine concentrations were measured by laboratory tests. Data were analyzed using odds ratio (OR) and logistic regression.</p><p><strong>Results: </strong>Forty-three percent of cases, and 26% of controls were positive for H. pylori IgG antibody, and this difference was not significant. The H. pylori seropositivity non significantly increased the risk of NTD-affected pregnancies (OR: 2.08; 95% confidence interval [CI]: 0.84-5.17, p=0.11). Serum vitamin B12 deficiency was detected in 17% of cases and 13% of controls, and folic acid deficiency in 17% of cases and 13% of controls (p=0.61). The H. pylori seropositivity was non significantly associated with low serum folate (OR 1.93 CI: 0.58-6.4, p=0.34) and ferritin (OR 1.24; CI: 0.42-3.60, p=0.68).</p><p><strong>Conclusion: </strong>Maternal H. pylori infection can increase the risk of occurrence of NTDs in newborns.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"219-25"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zong-Gang Hou, Zhen Wu, Jun-Ting Zhang, Zhong-Cheng Wang
{"title":"Pathological laughter in a patient with a brain-stem epidermoid cyst.","authors":"Zong-Gang Hou, Zhen Wu, Jun-Ting Zhang, Zhong-Cheng Wang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"265-6"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epilepsy and driving.","authors":"Sonia A Khan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"197-9"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bandar N Al-Jafen, Mohammed H Alanazy, James N Scott, Neelan Pillay
{"title":"Magnetic resonance imaging of crossed cerebellar diaschisis and bright pulvinar in status epilepticus.","authors":"Bandar N Al-Jafen, Mohammed H Alanazy, James N Scott, Neelan Pillay","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Crossed cerebellar diaschisis and bright pulvinar are rare in patients with status epilepticus. We present a case of a 53-year-old man who was found confused, incontinent, and nonverbal. The EEG findings were consistent with non-convulsive status epilepticus. The brain MR images showed findings consistent with crossed cerebellar diaschisis and bright pulvinar. We report and discuss this case to increase the awareness of these MRI signs in confused and obtunded patients.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"259-61"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protracted disease course after deafness in a man with Brown-Vialetto-Van Laere syndrome.","authors":"Samira Yadegari, Keyvan Razmjoo, Shahriar Nafissi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Brown-Vialetto-Van Laere syndrome (BVVLS) is a rare type of motor neuron disease, characterized by bilateral deafness, and multiple cranial nerve involvement. The disease is more frequent in females, but rapid deterioration was attributed to male gender or early onset. Herein, we report a man with BVVLS who had a longer than expected interval between onset of deafness and other motor symptoms that culminated to diagnosis. Six years later, he had gradual worsening and death. Along with potential new developing therapeutic options, this case emphasizes considering the diagnosis of BVVLS especially after a long period of stability, even in men.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"253-5"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Variable influence of the degree of smoking dependence on adult attention deficit/hyperactivity disorder in Iraqi medical students.","authors":"Ammar W Ashor","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To demonstrate the differences in the patterns of adult attention deficit/hyperactivity disorder (ADHD) symptoms among non, light, and heavy smokers.</p><p><strong>Methods: </strong>A cross-sectional study involving 400 medical students (representing first to sixth year students) was conducted in the Department of Pharmacology, University of Al-Mustansiriya, Baghdad, Iraq from March to June 2011. The medical students completed a questionnaire containing the adult ADHD self-report scale (ASRS-screener) and the Fagerstrom Test for Nicotine Dependence (FTND). An ADHD score ≥14 was considered positive. An FTND score ≥6 signifies heavy smokers, and an FTND score ≤5 signifies light smokers.</p><p><strong>Results: </strong>Three hundred and sixty-one medical students completed the questionnaire, 16.6% reported ADHD symptoms (19.8% male, 12.1% females). Forty-five percent of ADHD adults were smokers; more than half of them were categorized as heavy smokers (51.8%). In comparison with non-smokers, heavy smokers displayed significant deterioration in their inattentive and total ASRS score (p=0.0001). Light smokers show significantly higher hyperactive symptoms in comparison with non-smokers (p=0.041). A high FTND score was associated with severer deterioration in inattentive (r=0.391, p=0.001) but not hyperactive symptoms (r=0.153, p=0.117).</p><p><strong>Conclusion: </strong>The ADHD symptoms are highly prevalent among Iraqi medical students, and smoking among ADHD students is higher and heavier than non-ADHD controls. Heavy smoking tends to deteriorate rather than ameliorate (self-medicate) ADHD symptoms.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"241-7"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-reported side effects of lamotrigine during routine clinic visits.","authors":"Nur A Daud, Abfatah Ab-Rahman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"269-70"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ramsay Hunt syndrome with multiple cranial neuropathies in a liver transplant recipient.","authors":"Fawzi A Babtain, Harsha S Bhatia, Amer H Assiri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ramsay Hunt syndrome is an infection of the head and neck caused by varicella zoster virus involving the facial nerve; less commonly, other cranial nerves might be involved. We report a case of Ramsay Hunt syndrome in an immune compromised patient, with classic facial nerve palsy and ipsilateral ear vesicles, which rapidly evolved to involve multiple cranial neuropathies, and improved dramatically with antiviral therapy and corticosteroids. Varicella zoster virus should be considered as a cause of multiple cranial neuropathies in an immune compromised patient, and abrupt treatment with acyclovir should be initiated once this diagnosis is suspected.</p>","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"262-4"},"PeriodicalIF":0.9,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30746003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}