Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde最新文献

{"title":"[Symptoms of SARS-CoV-2 infections in children of day care age].","authors":"Juliane Wurm,&nbsp;Ann-Sophie Lehfeld,&nbsp;Gianni Varnaccia,&nbsp;Helena Iwanowski,&nbsp;Bianca Finkel,&nbsp;Anja Schienkiewitz,&nbsp;Hanna Perlitz,&nbsp;Anne-Kathrin Mareike Loer,&nbsp;Barbara Wess,&nbsp;Andrea Franke,&nbsp;Antje Hüther,&nbsp;Tim Kuttig,&nbsp;Anna Sandoni,&nbsp;Ulrike Kubisch,&nbsp;Susanne Jordan,&nbsp;Walter Haas,&nbsp;Udo Buchholz,&nbsp;Julika Loss","doi":"10.1007/s00112-022-01640-3","DOIUrl":"https://doi.org/10.1007/s00112-022-01640-3","url":null,"abstract":"<p><strong>Background: </strong>The symptoms of SARS-CoV‑2 infections in children are mostly mild; however, the symptoms are highly variable. There are only a few studies on non-hospitalized children. The clinical picture described in hospitalized children cannot be transferred to non-hospitalized children and the frequency of certain symptoms in children may thus be overestimated. Furthermore, most studies include a broad age group (up to 18 years). The symptoms of younger children have so far been described in less detail.</p><p><strong>Objective: </strong>The paper aims to describe the frequency of COVID-19 symptoms in younger children (1-6 years old). Data of the two modules COALA (<i>Corona: Anlassbezogene Untersuchungen in Kitas</i>) and CATS (Corona-KiTa surveillance) of the Corona-KiTa study are evaluated and the results of the two studies are compared and discussed against the background of the different methodologies. In the COALA study, the type and frequency of symptoms of children infected with SARS-CoV‑2 are evaluated and compared to symptoms of children who tested negative for SARS-CoV‑2. Symptom frequencies of SARS-CoV‑2 infected children of the COALA study are compared with data collected from surveillance data (CATS).</p><p><strong>Material and methods: </strong>The COALA study investigated 30 SARS-CoV‑2 outbreaks in day care centers where at least 1 SARS-CoV‑2 case was reported between October 2020 and June 2021. Using a prospective study design, day care children who were infected with SARS-CoV‑2 and their contact persons were studied over a period of 12 days (including regular SARS-CoV‑2 testing, retrospective interviews and daily symptom reporting). The results from the COALA study were compared with data from COVID-19 surveillance cases (CATS) for the same age group and time period. In Germany, SARS-CoV‑2 cases are reported to the local health authorities by physicians and laboratories. When reporting cases symptoms can be reported as well.</p><p><strong>Results: </strong>From the COALA study, interview and reported symptom data were available for 289 children from the participating day care centers. Of 39 children with a SARS-CoV‑2 infection (wild-type, α‑variant), 64% had at least 1 symptom; of the children who tested negative for SARS-CoV‑2, 40% had at least 1 symptom. In both groups, rhinitis was the most common symptom (36% vs. 25%, n. s.). From the surveillance data (CATS), clinical information was available for 84,371 SARS-CoV‑2 positive children; fever was most common (27%) along with rhinitis (26%). Severe symptoms such as dyspnea were rarely reported in the outbreak investigations and in the surveillance data (3% and 1%, respectively).</p><p><strong>Conclusion: </strong>Day care-aged children infected with SARS-CoV‑2 usually have mild or asymptomatic courses. Their symptoms are similar to those of children who tested negative for SARS-CoV‑2 from the same day care centers; thus, the observed COVID-19 symptoms are n","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"1113-1121"},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40698125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[PIMS/MIS-C in the omicron wave].","authors":"Reinhold Kerbl","doi":"10.1007/s00112-022-01578-6","DOIUrl":"https://doi.org/10.1007/s00112-022-01578-6","url":null,"abstract":"","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"863-864"},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40610293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pediatrics up to date-Brief notes on research].","authors":"R Kerbl","doi":"10.1007/s00112-021-01143-7","DOIUrl":"https://doi.org/10.1007/s00112-021-01143-7","url":null,"abstract":"","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"301-302"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-021-01143-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25475372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Medical child protection during the coronavirus lockdown].","authors":"T Heimann,&nbsp;J Ewert,&nbsp;F Metzner,&nbsp;F Sigmund,&nbsp;A Jud,&nbsp;S Pawils","doi":"10.1007/s00112-021-01135-7","DOIUrl":"https://doi.org/10.1007/s00112-021-01135-7","url":null,"abstract":"<p><strong>Background: </strong>There are indications that during the lockdown and the measures of social distancing due to the coronavirus disease 2019 (COVID-19) pandemic, physical and sexual child abuse and neglect may have increased. Additionally, decreased social control may have led to a lower detection rate of child protection cases.</p><p><strong>Objective: </strong>This study aimed to better understand the impact of the lockdown in Germany on the frequency and severity of child abuse and neglect. To do so the quantity and quality of cases of suspected child abuse and neglect in German pediatric departments and outpatient departments for medical child protection were examined.</p><p><strong>Methods: </strong>In May 2020 a total of 343 institutions of medical child protection were invited to fill in a questionnaire with items describing their institution and items depicting cases of child protection in March and April 2019 and 2020 regarding age, form and severity of abuse as well as items to describe particular remarks and ideas for child protection during the pandemic.</p><p><strong>Results: </strong>Out of the 343 pediatric departments and outpatient departments of medical child protection invited, the participation rate was 46%. In this study 81 institutions reported the total cases of suspected child abuse or neglect for both March and April 2019 and 2020. The number of cases dropped from 454 to 387 (-15%) in outpatient child abuse clinics and from 307 to 246 (-20%) in pediatric inpatient departments. Regarding the age of affected children and the form of abuse no significant differences were found.</p><p><strong>Conclusion: </strong>The study found a decrease in reported cases of suspected child abuse and neglect during the lockdown in March and April 2020 compared to 2019. While the results do not show an increase of total child abuse and neglect, as suspected by many professionals, the decrease in reported cases may be explained by a steep increase in unreported cases due to reduced social control.</p>","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"346-352"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-021-01135-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25389001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Coronavirus disease 2019].","authors":"Reinhold Kerbl,&nbsp;Fred Zepp","doi":"10.1007/s00112-021-01158-0","DOIUrl":"https://doi.org/10.1007/s00112-021-01158-0","url":null,"abstract":"","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"308-311"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-021-01158-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25573084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[PIMS-a new pediatric challenge].","authors":"S Samueli,&nbsp;T Wagner,&nbsp;C Scheibenpflug,&nbsp;O Janata,&nbsp;A Seeber,&nbsp;J Astl,&nbsp;H Kurz","doi":"10.1007/s00112-021-01139-3","DOIUrl":"https://doi.org/10.1007/s00112-021-01139-3","url":null,"abstract":"<p><p>The boy of Egyptian origin was previously healthy. After a history of fever for 7 days, abdominal pain, vomiting and dry cough resistant to treatment with oral antibiotics, he was admitted to hospital. The clinical examination showed a slightly red throat, a tense abdomen and erythema. The blood tests revealed leukocytosis and significantly increased inflammatory parameters. The abdominal ultrasound showed thickened intestinal loops in the left lower abdomen and the echocardiography showed minimal mitral regurgitation, a narrow pericardial effusion lamella over both ventricles and normal coronary arteries. Accordingly, cardiac enzymes were elevated. The day after admission, the boy developed an increasing rash and was transferred to the PICU because of septic shock refractory to high volume resuscitation, requiring hemodynamic support with noradrenaline and noninvasive respiratory assistance. The initial testing for SARS-CoV‑2 on nasopharyngeal aspirates was negative twice; however, serum IgG antibodies were positive. Other viral and bacterial infections were excluded as the cause of the symptoms.The patient received IVIG, ASS, furosemide and methylprednisolone and the antibiotic treatment was continued. The dosage of the catecholamine could be reduced according to the patient's condition and the serially performed echocardiographic findings. The patient recovered in his general condition and was discharged from the PICU after 8 days. With the help of a detailed family history, we were able to figure out that the whole family, including the patient himself, had symptoms of a cold about 1 month earlier. Hence, SARS-CoV‑2 antibody tests carried out showed a positive result for all of them.Pediatric inflammatory multisystem syndrome (PIMS) can quickly lead to manifest shock symptoms, necessitating close monitoring. A PICU background is crucial to treat possibly occurring symptoms and complications. High-dose steroids are used therapeutically alongside supportive therapies.</p>","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"317-321"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-021-01139-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25449914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitteilungen der ÖGKJ.","authors":"","doi":"10.1007/s00112-020-00930-y","DOIUrl":"https://doi.org/10.1007/s00112-020-00930-y","url":null,"abstract":"","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"564-572"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-020-00930-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38018981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitteilungen der ÖGKJ.","authors":"X X","doi":"10.1007/s00112-020-00967-z","DOIUrl":"https://doi.org/10.1007/s00112-020-00967-z","url":null,"abstract":"","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"661-668"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-020-00967-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38301240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Depressing timeliness].","authors":"R Berner","doi":"10.1007/s00112-020-00915-x","DOIUrl":"https://doi.org/10.1007/s00112-020-00915-x","url":null,"abstract":"","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"485-487"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-020-00915-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38018982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Adenovirus infections].","authors":"A Heim","doi":"10.1007/s00112-020-00909-9","DOIUrl":"https://doi.org/10.1007/s00112-020-00909-9","url":null,"abstract":"<p><p>During childhood several adenovirus infections have to be experienced, each with another of the multiple types. The spectrum of associated diseases ranges from endemic, mild and self-limiting upper respiratory tract infections to epidemic gastroenteritis, eye infections, cystitis and less frequently atypical pneumonia and severe infections of internal organs; however, the vast majority of adenovirus infections during childhood are not life threatening with the exception of the infrequent infections of neonates and the frequent infection of hematopoietic stem cell recipients (disseminated disease).</p>","PeriodicalId":520712,"journal":{"name":"Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde","volume":" ","pages":"514-523"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00112-020-00909-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37874372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}