{"title":"Abstracts from the NIH Office of Research on Women's Health 2025 Annual BIRCWH Meeting: Building Interdisciplinary Research Careers in Women's Health November 4, 2025.","authors":"","doi":"10.1177/15409996251365000","DOIUrl":"https://doi.org/10.1177/15409996251365000","url":null,"abstract":"","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":"34 10","pages":"e1290-e1313"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashwini Nadkarni, Mary Shen, Sarah Temkin, Amy Vinson, Kevin M Simon, Elizabeth I O Garner, Julie D Cantor, Marie Brown, Ishani Ganguli, Julie K Silver, John A Fromson
{"title":"Reducing Burnout in Women Physicians: An Organizational Roadmap from the Harvard Radcliffe Institute Exploratory Seminar.","authors":"Ashwini Nadkarni, Mary Shen, Sarah Temkin, Amy Vinson, Kevin M Simon, Elizabeth I O Garner, Julie D Cantor, Marie Brown, Ishani Ganguli, Julie K Silver, John A Fromson","doi":"10.1177/15409996251360551","DOIUrl":"10.1177/15409996251360551","url":null,"abstract":"<p><p><b><i>Background:</i></b> Women physicians comprise more than half of graduating medical students in the United States, yet their rates of burnout and attrition from academic medicine are higher than for men physicians across every career stage. <b><i>Objective:</i></b> In May 2024, the Radcliffe Institute for Advanced Study at Harvard University convened international experts on physician gender inequity and well-being for an exploratory seminar. The goal was to establish consensus on an institutional roadmap to mitigate burnout in women physicians. <b><i>Methods:</i></b> We addressed 3 main questions through presentations, roundtable discussions, and the screening of an award winning physician-directed and -produced film on the subject: (1) What are major organizational drivers of women physician burnout and institutional best practices to address these drivers? (2) What barriers hinder successful implementation of best practices? (3) How can institutions overcome these barriers? Through iterative dialogue during the seminar and post-hoc discussions on the conceptualization of this manuscript, our group reached a consensus on an institutional roadmap to diminish burnout in all physicians identifying as women. <b><i>Results:</i></b> We conceived a budget neutral, easily adopted, and sustainable institutional roadmap to mitigate burnout in women physicians. The roadmap is grounded in a learning health system and leverages data collection to drive iterative, structural changes that achieve meaningful impact on a culture of well-being. <b><i>Conclusions:</i></b> Organizational accountability for a culture of well-being is critical to diminish burnout in women physicians and should be approached through intentional, multi-pronged, structural changes which restore trust and achieve belonging.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":"1183-1191"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144629405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolyn Gaylord-King, Charlie L Harris, Shichen Xu, John W Salerno, Kenneth G Walton, C Noel Bairey-Merz, Sanford Nidich, Robert H Schneider
{"title":"A Multicenter Randomized Controlled Trial of Meditation and Health Education in the Prevention of Cardiometabolic Disease in Black Women.","authors":"Carolyn Gaylord-King, Charlie L Harris, Shichen Xu, John W Salerno, Kenneth G Walton, C Noel Bairey-Merz, Sanford Nidich, Robert H Schneider","doi":"10.1177/15409996251364663","DOIUrl":"10.1177/15409996251364663","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Black American women suffer from disproportionately high rates of cardiovascular disease (CVD). This disparity may be related to psychosocial stress and cardiometabolic risk factors. Therefore, the objective of this trial was to evaluate the efficacy of a stress-reducing meditation technique compared with health education on cardiometabolic disease endpoints in high CVD risk Black women. <b><i>Methods:</i></b> The participants were Black women with documented CVD or with high CVD risk scores. They were randomly allocated to either Transcendental Meditation (TM) or health education (HE) for one year. Cardiometabolic endpoints were tested at baseline and after 12 months. Outcomes were carotid intima-media thickness (cIMT), hemoglobin A1c (HbA1c), insulin resistance (homeostatic model assessment [HOMA] IR), blood lipids, blood pressure (BP), weight, and physical activity. <b><i>Results:</i></b> A total of 201 participants enrolled (average age 64.6). After 1 year, the TM and HE groups showed decreases in cIMT with no significant difference between groups. In a post hoc exploratory analysis, both TM and HE demonstrated reductions in cIMT compared with historical controls (<i>p</i> = 0.006). The TM group showed reductions in HbA1c (<i>p</i> = 0.0030) and HOMA IR compared with HE (<i>p</i> = 0.03) and increased HDL (<i>p</i> = 0.01). Systolic and diastolic BP decreased in both groups without significant difference. In the overweight/obese subgroup, there was nearly 5% weight loss in the TM compared to the HE group. <b><i>Discussion:</i></b> In high-risk Black women, TM or HE participation was associated with prevention of progression of cIMT, while the TM group showed improvements in cardiometabolic disease endpoints of HbA1c, IR, and HDL cholesterol and weight loss in overweight/obese participants.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":"1247-1256"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144786368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura B Harrington, Sarah E Tom, Chloe Krakauer, Paige D Wartko, Kristi Chau, Roxanne Muiruri, Elizabeth Micks, Linda K McEvoy, Andrea Z LaCroix, Eliza C Miller
{"title":"Adverse Pregnancy Outcomes and Cognitive Change in Older Women.","authors":"Laura B Harrington, Sarah E Tom, Chloe Krakauer, Paige D Wartko, Kristi Chau, Roxanne Muiruri, Elizabeth Micks, Linda K McEvoy, Andrea Z LaCroix, Eliza C Miller","doi":"10.1177/15409996251383009","DOIUrl":"https://doi.org/10.1177/15409996251383009","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Whether the history of adverse pregnancy outcomes (APOs) contributes to cognitive decline in women is unclear. <b><i>Methods:</i></b> Among parous female Adult Changes in Thought (ACT) participants (aged ≥ 65 years without dementia at enrollment), we abstracted APO history for those born 1940 or later and enrolled between 2005 and 2020 (<i>n</i> = 444). Generalized estimating equations estimated the association between APO history and cognition score, measured using the Cognitive Abilities Screening Instrument assessment using item response theory (CASI-IRT), and cognitive decline. <b><i>Results:</i></b> Among all participants, 13% had a history of APO. In adjusted models, women with an APO history had 0.23-point lower CASI-IRT score at any age (95% confidence interval: -0.54, 0.07); this small difference was not statistically significant. We found no evidence of an association between APO history and 4-year cognitive change. <b><i>Conclusion:</i></b> Among women in the ACT study born in 1940 or later, we found no evidence of a significant association between history of APO and lower cognition or cognitive decline in older adulthood.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145188238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zélia Breton, Solène Gouesbet, Emilie Indersie, Marie Gabillet, Viet-Thi Tran, Nizar Aflak, Bruno Borghese, Erick Petit, Horace Roman, Anne-Charlotte Millepied, Margaux Nève De Mevergnies, Marina Kvaskoff
{"title":"Endometriosis Diagnostic Delay and Its Correlates: Results from the ComPaRe-Endometriosis Cohort.","authors":"Zélia Breton, Solène Gouesbet, Emilie Indersie, Marie Gabillet, Viet-Thi Tran, Nizar Aflak, Bruno Borghese, Erick Petit, Horace Roman, Anne-Charlotte Millepied, Margaux Nève De Mevergnies, Marina Kvaskoff","doi":"10.1177/15409996251380129","DOIUrl":"https://doi.org/10.1177/15409996251380129","url":null,"abstract":"<p><p><b><i>Background:</i></b> An average time to diagnosis of 7 years is commonly described for endometriosis; diagnostic delay for adenomyosis is unknown. This cross-sectional study aimed to describe diagnostic delay for endometriosis and adenomyosis and to investigate the factors associated with this delay. <b><i>Methods:</i></b> Community of Patients for Research (ComPaRe)-Endometriosis is a prospective e-cohort of women with endometriosis and/or adenomyosis in France. About 6,949 participants were included. We used linear regression modeling to assess factors associated with diagnostic delay, after adjustment for age, education level, body mass index, number of comorbidities, and family history of the disease or of chronic pelvic pain (CPP). <b><i>Results:</i></b> The average diagnostic delay was 10 years for endometriosis and 11 years for adenomyosis. Factors associated with a significantly longer diagnostic delay were year of diagnosis (+0.34 years, <i>p</i> < 0.0001), unemployment (+0.7 years, <i>p</i> = 0.01), number of comorbidities (+0.3 years, <i>p</i> < 0.0001), family history of the disease or of CPP (+1.1 years, <i>p</i> < 0.0001), severe dysmenorrhea before diagnosis (numeric-rating scale: +0.8 years, <i>p</i> < 0.0001), number of health professionals consulted before diagnosis (+0.3 years, <i>p</i> < 0.0001), and presence of multiple symptoms leading to first consultation (+1.6 years, <i>p</i> < 0.0001). In contrast, factors associated with a shorter delay were a financial position perceived as comfortable (-1.4 years, <i>p</i> < 0.0001), age at menarche (-0.6 years, <i>p</i> < 0.0001), and age at first symptoms (-0.8 years, <i>p</i> < 0.0001). <b><i>Conclusions:</i></b> This study highlights several factors associated with diagnostic delay among women with self-reported endometriosis and/or adenomyosis and provides new insights to improve care by informing both clinicians and patients. Attention to these profiles may improve disease management.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stacey B Griner, Malinee Neelamegam, Kaeli Johnson, Ashlyn Kinard, Alexandra N Farris, Amanda Brosnan, Meaghan Nelsen
{"title":"Awareness, Acceptability, and Adoption of Prenatal Syphilis Screening Guidelines.","authors":"Stacey B Griner, Malinee Neelamegam, Kaeli Johnson, Ashlyn Kinard, Alexandra N Farris, Amanda Brosnan, Meaghan Nelsen","doi":"10.1177/15409996251382057","DOIUrl":"https://doi.org/10.1177/15409996251382057","url":null,"abstract":"<p><p><b><i>Background:</i></b> Congenital syphilis rates have been increasing since 2012 and are associated with adverse health outcomes. There is variability in screening guidelines, and little is known about provider knowledge of them. The purpose was to assess the awareness and acceptability of prenatal syphilis guidelines among physicians. <b><i>Materials and Methods:</i></b> We cross-sectionally assessed prenatal provider (MD/DO; <i>n</i> = 201) awareness and adoption of national guidelines. Feasibility was assessed through the feasibility of the intervention measure, acceptability using the acceptability of the intervention measure, and appropriateness using the intervention appropriateness measure. Each measure included four items on a five-point Likert scale from strongly disagree (1) to strongly agree (5). The final analysis compared relative advantage, compatibility, complexity, observability, and trialability across the guidelines. Data analysis was completed in SAS v9.4, and this study was approved by the university's IRB. <b><i>Results:</i></b> Providers discussed (84%) and recommended (91%) prenatal syphilis screening to their patients. Providers (87%) were aware of their professional organizations' prenatal syphilis screening recommendations and utilized the American Academy of Pediatrics/American Congress of Obstetrics and Gynecology guideline (74%). Universal screening (62%), pregnancy trimester (54%), and professional organizations' recommended guidelines (54%) were associated with recommending syphilis screening to prenatal patients. The most important factor was universal screening (33%). The Centers for Disease Control and Prevention guideline had the highest mean relative advantage score (3.56, <i>p</i> = 0.020), and the United States Preventive Services Task Force guideline was viewed as significantly clearer (9.76) compared to the other guidelines (<i>p</i> = 0.007). <b><i>Conclusions:</i></b> Participants discussed and recommended prenatal syphilis screening to their patients despite variability in screening guidelines. Future studies should analyze guideline dissemination to fully understand the adoption process.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marguerite B Lucea, Andrea N Ramirez, Vijay Singh, Jacqueline C Campbell, Vinciya Pandian
{"title":"Homicides of Pregnant Women: Artificial Intelligence Detects Partner Violence and System Interaction.","authors":"Marguerite B Lucea, Andrea N Ramirez, Vijay Singh, Jacqueline C Campbell, Vinciya Pandian","doi":"10.1177/15409996251380353","DOIUrl":"https://doi.org/10.1177/15409996251380353","url":null,"abstract":"<p><p><b><i>Background:</i></b> Homicide ranks among the top causes of pregnancy-associated mortality in the United States. Intimate partner violence (IPV) has been implicated in violent maternal deaths, before which pregnant women may interact with health care, law enforcement, and legal systems. <b><i>Objective:</i></b> To understand IPV and system engagement prior to maternal deaths and to test the viability of using artificial intelligence (AI) for the analysis of narratives, we compared AI and human-rater analyses of National Violent Death Reporting System Restricted Access Data (NVDRS-RAD) narratives for IPV circumstances and system interactions. <b><i>Study Design:</i></b> We conducted a secondary data analysis of the female homicide records in the 2018-2020 NVDRS-RAD narratives. We trained a bidirectional encoder representations from transformers (BERT) model on 5,082 female nonpregnant cases, validating it with the 351 pregnant or recently pregnant cases. We conducted AI performance metrics for sensitivity, specificity, precision, and kappa values, identified key terms, and compared AI with human-rater analyses. <b><i>Results:</i></b> Among 351 complete NVDRS narrative records of pregnant or postpartum female homicide victims, 285 had primary suspects identified. Human-rater and AI analysis identified similar numbers for whether the suspect was a current or former partner and whether IPV history was noted before homicide. Natural language processing (NLP)-identified word patterns highlighted differences between IPV and non-IPV cases. Human raters identified 24% (80/351), compared with NLP's identification of 21% (72/351), of pregnant women before death who interacted with health care and other systems. All AI models had strong performance metrics. <b><i>Conclusions:</i></b> Pregnant women in violent relationships interact with health care, law enforcement, and legal systems prior to their deaths. AI analysis is comparable with human raters in detecting IPV circumstances and system interactions among maternal homicides in the NVDRS. These findings highlight missed opportunities across sectors, underlining the importance of multisectoral interventions to prevent homicides of pregnant women.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Ireland, Kristin Palmsten, Heather S Lipkind, Christina M Ackerman-Banks, Katherine A Ahrens
{"title":"Characteristics and Incidence of Lactational Mastitis Using State-Wide Data from 2016 to 2022.","authors":"Emily Ireland, Kristin Palmsten, Heather S Lipkind, Christina M Ackerman-Banks, Katherine A Ahrens","doi":"10.1177/15409996251380127","DOIUrl":"https://doi.org/10.1177/15409996251380127","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To estimate the characteristics and describe the incidence of lactational mastitis among postpartum people. <b><i>Methods:</i></b> We used Maine Health Data Organization's All Payer Claims Data for people who delivered during 2016-2022 with insurance coverage throughout pregnancy and 12 months postpartum and had a breast pump claim (as a proxy for breastfeeding) (<i>N</i> = 22520). We estimated the incidence of lactational mastitis within one year postpartum using International Classification of Diseases-Clinical Modification 10 diagnosis codes. We examined mastitis incidence by rurality of residence, delivery year, maternal age, parity (using a proxy measure), insurance type, pregnancy condition, and history of mastitis. We also assessed the timing and setting of the first mastitis diagnosis. <b><i>Results:</i></b> The incidence of lactational mastitis was 4.4% (95% CI: 4.1, 4.7). Persons with a higher incidence of mastitis included those living in metro areas (4.9%), 25-29 years old (4.6%), having commercial insurance coverage at delivery (5.0%), with their first or second delivery in the dataset (4.5%), and with a history of mastitis (13.9%). Overall, 15% of lactational mastitis was first diagnosed during an acute care encounter; however, this was higher among those living in isolated rural areas (22%), 20-24 years old (32%), having Medicaid insurance (24%), with three or more deliveries in the dataset (21%), and without a history of mastitis (18.5%). <b><i>Conclusion:</i></b> The incidence of diagnosed lactational mastitis varies by several maternal and pregnancy characteristics. Persons who are younger, live in rural areas, have Medicaid or have higher parity may face barriers to care in the primary care setting and ultimately be diagnosed with lactational mastitis during acute care encounters.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adit Doza, Lijing Ouyang, Donatus U Ekwueme, Romeo Galang, Brenda L Bauman, Lisa M Romero, Wanda D Barfield, Shanna Cox
{"title":"Patterns of Telehealth Use During Pregnancy and Postpartum Among Commercially Insured Women.","authors":"Adit Doza, Lijing Ouyang, Donatus U Ekwueme, Romeo Galang, Brenda L Bauman, Lisa M Romero, Wanda D Barfield, Shanna Cox","doi":"10.1177/15409996251378322","DOIUrl":"https://doi.org/10.1177/15409996251378322","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This study assesses telehealth use during pregnancy and postpartum among commercially insured women with live birth from 2019 to 2021. It also assesses differences in telehealth use by rural/urban status and describes the most frequently utilized services. <b><i>Methods:</i></b> We used the Merative MarketScan Commercial database for women aged 15-49 who had a live birth delivery between 2019 and 2021, with continuous insurance enrollment for 10 months predelivery and 12 months postdelivery. We described patient characteristics stratified by telehealth user (TU) versus non-telehealth user (NTU) for all cohorts based on year of delivery. The major diagnostic categories (MDCs) were used to assess service types of telehealth use. <b><i>Results:</i></b> The total telehealth visits during predelivery and postpartum periods were 60,655 in 2019; 204,935 in 2020; and 276,425 in 2021. An increasing proportion of telehealth visits occurred in the predelivery period (2.8% in 2019, 24.2% in 2020, and 46.1% in 2021). Across all cohorts, a higher proportion of TUs had diabetes (9.9%-12.8% versus 6.2%-7.3%), hypertension (6.0-6.6% versus 3.7%-4.4%), and depression (6.4%-7.6% versus 1.3-2.3%) compared with NTUs. Lower proportion of TUs lived in rural areas compared with NTUs (6.6%-7.3% versus 11.2%-13.0%). The MDC for mental health services was present for greater than 50% of telehealth visits during postpartum. <b><i>Conclusion:</i></b> Increased telehealth visits for mental health services among pregnant and postpartum women suggest more accessible care or heightened mental health needs. Further research may determine if increased telehealth use improves maternal and birth outcomes.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145116019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonya S Brady, Linda Brubaker, Deepa R Camenga, Chloe Falke, Colleen M Fitzgerald, Sheila Gahagan, Terri H Lipman, Lisa Kane Low, Melissa Marquez, Jenna M Norton, Todd Rockwood, Kyle D Rudser, Ariana L Smith, Siobhan Sutcliffe, Camille P Vaughan, Amanda K Berry
{"title":"Associations of Self-Rated Deficits in Executive Function with Lower Urinary Tract Symptoms, Adaptive Behaviors, and Bladder Health among Women.","authors":"Sonya S Brady, Linda Brubaker, Deepa R Camenga, Chloe Falke, Colleen M Fitzgerald, Sheila Gahagan, Terri H Lipman, Lisa Kane Low, Melissa Marquez, Jenna M Norton, Todd Rockwood, Kyle D Rudser, Ariana L Smith, Siobhan Sutcliffe, Camille P Vaughan, Amanda K Berry","doi":"10.1177/15409996251380351","DOIUrl":"https://doi.org/10.1177/15409996251380351","url":null,"abstract":"<p><p><b><i>Background:</i></b> Poorer performance on standardized tests of cognitive function is associated with urinary incontinence (UI), overactive bladder, and poorer bladder health among people aged 40 and older. <b><i>Objective:</i></b> To examine whether self-rated deficits in executive function domains (organization/problem solving, inhibitory control/self-restraint, self-regulation of emotions) are associated with lower urinary tract symptoms (LUTS), perceived bladder health and function, and adaptive behaviors to prevent or manage UI among adult women across the life course. <b><i>Methods:</i></b> Surveys were administered as part of the RISE FOR HEALTH population-based study of women (19-100 years, mean = 50 years) in the United States. In this cross-sectional analysis, LUTS, perceived bladder health and function, and adaptive behaviors were regressed on individual executive function subscales and a composite measure (analytic sample <i>n</i> = 1,551). <b><i>Results:</i></b> Self-rated deficits in all evaluated domains of executive function were significantly associated with greater numbers and frequency of LUTS, including urgency and urgency UI; poorer perceived bladder health and function; and a greater tendency to locate bathrooms when entering new places. Associations were of similar magnitude across age categories ranging from emerging to older adulthood. <b><i>Conclusions:</i></b> Findings demonstrate an association between self-rated executive function deficits and bladder function. Further research should test brain-bladder communication as a potential mechanism linking deficits in executive function to greater numbers and frequency of LUTS, poorer perceived bladder health and function, and greater engagement in adaptive behaviors to prevent or manage UI. Research is also needed to further evaluate whether associations between executive function and LUTS differ by life course stage.</p>","PeriodicalId":520699,"journal":{"name":"Journal of women's health (2002)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145116023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}