Travis Quevillon, Justin Chiu, Peter Amlogu, Faith Michael, William F McIntyre, Ratika Parkash, Jason G Andrade, Cynthia A Jackevicius, Jeff S Healey, Dennis T Ko, Mohammed Shurrab
{"title":"Outcomes of individual DOACs vs. VKAs in AF patients with frailty: a systematic review and meta-analysis.","authors":"Travis Quevillon, Justin Chiu, Peter Amlogu, Faith Michael, William F McIntyre, Ratika Parkash, Jason G Andrade, Cynthia A Jackevicius, Jeff S Healey, Dennis T Ko, Mohammed Shurrab","doi":"10.1007/s10840-026-02263-4","DOIUrl":"10.1007/s10840-026-02263-4","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1849-1858"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Valerio Mariani, Tommaso Recchioni, Marta Palombi, Nicola Pierucci, Raffaele Maria Bruti, Pietro Cipollone, Domenico Laviola, Sara Trivigno, Andrea Matteucci, Agostino Piro, Cristina Chimenti, Carmine Dario Vizza, Carlo Lavalle
{"title":"Empiric superior vena cava isolation in atrial fibrillation ablation: an updated meta-analysis.","authors":"Marco Valerio Mariani, Tommaso Recchioni, Marta Palombi, Nicola Pierucci, Raffaele Maria Bruti, Pietro Cipollone, Domenico Laviola, Sara Trivigno, Andrea Matteucci, Agostino Piro, Cristina Chimenti, Carmine Dario Vizza, Carlo Lavalle","doi":"10.1007/s10840-026-02290-1","DOIUrl":"10.1007/s10840-026-02290-1","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1551-1553"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147392228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and safety of ventricular tachycardia ablation versus antiarrhythmics in ischemic cardiomyopathy: a network meta-analysis.","authors":"Konstantinos Pamporis, Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Serge Boveda, Athanasios Kordalis, Konstantinos Vlachos, Pierre Jaïs, Paschalis Karakasis, Michail Botis, Panagiotis Theofilis, Aikaterini-Eleftheria Karanikola, Konstantinos Tsioufis","doi":"10.1007/s10840-026-02250-9","DOIUrl":"10.1007/s10840-026-02250-9","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1871-1884"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146260563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ourania Kariki, Konstantinos Pamporis, Athanasios Saplaouras, Panagiotis Mililis, Theodoros Efremidis, Antonios Martinos, Stavroula Koskina, Anna Kostopoulou, George Poulos, Stylianos Dragasis, Eleni Nikoli, Konstantinos P Letsas, Michael Efremidis
{"title":"Biochemical evidence and clinical significance of hemolysis following catheter ablation with a lattice-tip PFA catheter.","authors":"Ourania Kariki, Konstantinos Pamporis, Athanasios Saplaouras, Panagiotis Mililis, Theodoros Efremidis, Antonios Martinos, Stavroula Koskina, Anna Kostopoulou, George Poulos, Stylianos Dragasis, Eleni Nikoli, Konstantinos P Letsas, Michael Efremidis","doi":"10.1007/s10840-025-02163-z","DOIUrl":"10.1007/s10840-025-02163-z","url":null,"abstract":"<p><strong>Background: </strong>Intravascular hemolysis(IH) is an inherent limitation of pulsed field ablation(PFA) technology. The severity of IH is multifactorial and differs between PFA systems. This study aimed to assess the biochemical evidence and clinical significance of IH induced by a lattice-tip PFA catheter.</p><p><strong>Methods: </strong>Patients with atrial fibrillation(AF) undergoing catheter ablation with a lattice-tip PFA catheter or with radiofrequency (RF) (50/90 W) were eligible. Changes in haptoglobin, hemoglobin(Hb), lactate dehydrogenase(LDH), indirect bilirubin, and creatinine were assessed in blood samples collected at baseline (T0), immediately (T1), and 24-h (T2) post-ablation. Clinically relevant IH was defined as changes in biochemical markers of hemolysis in combination with a hemoglobin drop ≥ 2 g/dL or renal biomarker changes fulfilling criteria for AKI. Furthermore, in order to properly interpret the observed changes in haptoglobin, \"biochemical events\" previously associated with direct markers of IH were analyzed [(T2 haptoglobin ≤ 0.25 g/l, T2/T0 haptoglobin ratio < 0.85, and T2-T0 haptoglobin difference < Q1 (-0.1 g/l)].</p><p><strong>Results: </strong>A total of 142 patients [102/142 (72%) in PFA group; 40/142 (28%) in RF group] were included, with comparable characteristics. Significant changes in Hb and LDH were found in both groups. The PFA group experienced a greater decrease in haptoglobin levels compared to RF (MD = -0.02 g/L, 95% CI [-0.04, 0]; p = 0.043), while \"biochemical events\" were infrequent and similar between groups. None of the participants fulfilled the definition of clinically relevant IH. In the PFA group, the number of lesions was marginally associated with greater biomarker changes.</p><p><strong>Conclusions: </strong>In this observational real-world cohort, the lattice-tip PFA catheter was associated with statistically significant, yet relatively small reductions of haptoglobin post-procedurally compared to RF, with no case of clinically relevant IH being reported.</p>","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1745-1753"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lessons learned from the first in human sequential colocalized PFA and RF lesions.","authors":"Daniel Alyesh, Nicholas Palmeri, Sri Sundaram","doi":"10.1007/s10840-025-02103-x","DOIUrl":"10.1007/s10840-025-02103-x","url":null,"abstract":"<p><p>The era of pulsed field ablation (PFA) has yielded considerable improvements in procedural safety for atrial fibrillation. However, given the fixed size and depth of the electrical field in first generation PFA modalities, ablation of substrates beyond the pulmonary veins with heterogeneity of tissue thickness can be challenging. Sequential PFA and radiofrequency (RF) from a focal tip catheter may offer an advantage in these challenging substrates with potential to deliver safe and deeper lesions. In our report, we describe the first in human experience of sequential colocalized PFA and RF lesions with a 3.5-mm investigational dual energy catheter.</p>","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1579-1584"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francis J Ha, Sarah Paitry, Duron Prinsloo, Hui-Chen Han, Adam J Brown, Nitesh Nerlekar, Emily Kotschet
{"title":"Correction: Repeat procedures after pulsed field ablation for atrial fibrillation: tertiary centre experience and meta-analysis of observational studies.","authors":"Francis J Ha, Sarah Paitry, Duron Prinsloo, Hui-Chen Han, Adam J Brown, Nitesh Nerlekar, Emily Kotschet","doi":"10.1007/s10840-026-02287-w","DOIUrl":"10.1007/s10840-026-02287-w","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1847"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility of slow conduction velocity area guided ablation in patients with persistent atrial fibrillation.","authors":"Yousaku Okubo, Shunsuke Ishida, Sho Okamura, Naoki Ishibashi, Oe Hiroshi, Junji Maeda, Takumi Sakai, Naoto Oguri, Motoki Furutani, Shogo Miyamoto, Shunsuke Miyauchi, Takehito Tokuyama, Noboru Oda, Yukiko Nakano","doi":"10.1007/s10840-026-02368-w","DOIUrl":"10.1007/s10840-026-02368-w","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary vein isolation (PVI) is a well-established treatment for atrial fibrillation (AF). However, in patients with persistent AF, PVI alone is often insufficient, and no adjunctive strategy with proven efficacy beyond PVI has been established. Recently, increasing attention has been directed toward local atrial conduction velocity (CV). Slow conduction velocity areas (SCVAs) have been regarded as potential arrhythmogenic substrates, and ablation strategies targeting SCVAs are under investigation. This study evaluated the efficacy of SCVA-guided ablation in patients with persistent AF.</p><p><strong>Methods: </strong>We enrolled 175 patients with persistent AF who underwent initial radiofrequency catheter ablation (RFCA). SCVAs were defined as contiguous atrial regions with a local CV < 0.7 m/s and a surface area ≥ 2.0 cm². SCVA-guided ablation was performed in 84 patients, whereas standard anatomical PVI was performed in 91 patients. The primary outcome was recurrence of AF or occurrence of new-onset supraventricular tachycardia during a two-year follow-up period.</p><p><strong>Results: </strong>During follow-up, clinical recurrence occurred in 63 patients (36.0%). Patients in the SCVA-guided ablation group demonstrated a significantly higher recurrence-free survival rate compared with those in the standard PVI group (72.6% vs. 56.1%; log-rank P = 0.01). Multivariate analysis identified SCVA-guided ablation (hazard ratio [HR] 0.31, 95% confidence interval [CI] 0.21-0.67, P = 0.003) and left atrial (LA) volume index (HR 1.03, 95% CI 1.01-1.06, P = 0.001) as independent predictors of AF recurrence.</p><p><strong>Conclusion: </strong>SCVAs represent important arrhythmogenic substrates. Incorporating these regions into PVI significantly reduced AF recurrence compared with standard anatomical PVI.</p>","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1987-1995"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148202079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandro Cuesta, María J Arocena, José M Moltedo, Fernando Vidal, Pedro Iturralde, Manlio Márquez-Murillo, Moisés Levinstein J, Santiago Nava, Gerardo Rodríguez-Diez, Elaine Nuñez, Luis Wayar, Luis J Colin Lizalde, Jorge R Gómez Flores, José L Morales, Rogelio Robledo, Alejandro Estrada, Andrés Caeiro, Katty Quezada, Álvaro Arenas, Michel Cabrera Ortega
{"title":"Ablation of manifest accessory pathways in pediatric patients: comparison between conventional and non‑radiological navigation techniques.","authors":"Alejandro Cuesta, María J Arocena, José M Moltedo, Fernando Vidal, Pedro Iturralde, Manlio Márquez-Murillo, Moisés Levinstein J, Santiago Nava, Gerardo Rodríguez-Diez, Elaine Nuñez, Luis Wayar, Luis J Colin Lizalde, Jorge R Gómez Flores, José L Morales, Rogelio Robledo, Alejandro Estrada, Andrés Caeiro, Katty Quezada, Álvaro Arenas, Michel Cabrera Ortega","doi":"10.1007/s10840-026-02260-7","DOIUrl":"10.1007/s10840-026-02260-7","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1829-1834"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deepak Saluja, Jonah A Majumder, Lawrence Zeldin, Haiqiu Yang, Hirad Yarmohammadi, Elaine Y Wan, Edward J Ciaccio, Christine P Hendon, Angelo Biviano
{"title":"Automated analysis of electrogram characteristics in baseline rhythm can distinguish isthmus regions and segments in reentrant ventricular tachycardia.","authors":"Deepak Saluja, Jonah A Majumder, Lawrence Zeldin, Haiqiu Yang, Hirad Yarmohammadi, Elaine Y Wan, Edward J Ciaccio, Christine P Hendon, Angelo Biviano","doi":"10.1007/s10840-026-02261-6","DOIUrl":"10.1007/s10840-026-02261-6","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1777-1787"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcomes after ventricular tachycardia ablation in patients with left ventricular assist device: a retrospective multicenter cohort study.","authors":"Shamin Hayat Mahmud, Amish Jain, Zaid Shahrori, Kunal Gupta, Sheila Sharma, Mauricio Arruda, Ivan Cakulev, Shashank Jain, Sergio Thal, Judith Mackall, Esseim Sharma","doi":"10.1007/s10840-026-02334-6","DOIUrl":"10.1007/s10840-026-02334-6","url":null,"abstract":"","PeriodicalId":520675,"journal":{"name":"Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing","volume":" ","pages":"1589-1590"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}