Journal of exposure science & environmental epidemiology最新文献

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Environmental exposure scenarios: development, challenges and possible solutions. 环境暴露情景:发展、挑战和可能的解决方案。

IF 4.5

Journal of exposure science & environmental epidemiology Pub Date : 2007-12-01 Epub Date: 2007-11-14 DOI: 10.1038/sj.jes.7500602

Andreas Ahrens, Theo P Traas

{"title":"Environmental exposure scenarios: development, challenges and possible solutions.","authors":"Andreas Ahrens, Theo P Traas","doi":"10.1038/sj.jes.7500602","DOIUrl":"https://doi.org/10.1038/sj.jes.7500602","url":null,"abstract":"Under the new REACH system, companies importing, producing and marketing chemical substances will be obliged to register the single substances and to carry out a safety assessment for all identified uses during the life cycle of the substance. This duty will apply to about 10,000 existing substances in the EU market exceeding an annual production or import volume of 10 t per company. If the substance is already known to be dangerous or turns out to be dangerous(1) during the hazard assessment, the registrant is obliged to carry out an exposure assessment and a risk characterisation for all identified uses. The goal of the safety assessment is to define the conditions of use that allow for adequate control of risk with regard to health and safety at the work place, consumer safety and protection of the environment. Once the registrant has established and documented these conditions in the Chemicals Safety Report (CSR), that information is to be communicated down the supply chain by means of the Extended Safety Data Sheet (eSDS). The ultimate aim of the new legislation is to establish duties and mechanisms that systematically prevent or limit exposure to dangerous industrial chemicals. The current paper explains this concept with regard to environmental exposure and highlights the challenges and possible solutions.","PeriodicalId":520670,"journal":{"name":"Journal of exposure science & environmental epidemiology","volume":" ","pages":"S7-15"},"PeriodicalIF":4.5,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/sj.jes.7500602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41030225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Exposure scenarios for workers. 工人的暴露情景。

IF 4.5

Journal of exposure science & environmental epidemiology Pub Date : 2007-12-01 Epub Date: 2007-09-12 DOI: 10.1038/sj.jes.7500617

Hans Marquart, Christine Northage, Chris Money

{"title":"Exposure scenarios for workers.","authors":"Hans Marquart, Christine Northage, Chris Money","doi":"10.1038/sj.jes.7500617","DOIUrl":"https://doi.org/10.1038/sj.jes.7500617","url":null,"abstract":"The new European chemicals legislation REACH (Registration, Evaluation, Authorisation and restriction of Chemicals) requires the development of Exposure Scenarios describing the conditions and risk management measures needed for the safe use of chemicals. Such Exposure Scenarios should integrate considerations of both human health and the environment. Specific aspects are relevant for worker exposure. Gathering information on the uses of the chemical is an important step in developing an Exposure Scenario. In-house information at manufacturers is an important source. Downstream users can contribute information through direct contact or through their associations. Relatively simple approaches (Tier 1 tools, such as the ECETOC Targeted Risk Assessment and the model EASE) can be used to develop broad Exposure Scenarios that cover many use situations. These approaches rely on the categorisation of just a few determinants, including only a small number of risk management measures. Such approaches have a limited discriminatory power and are rather conservative. When the hazard of the substance or the complexity of the exposure situation require a more in-depth approach, further development of the Exposure Scenarios with Tier 2 approaches is needed. Measured data sets of worker exposure are very valuable in a Tier 2 approach. Some downstream user associations have attempted to build Exposure Scenarios based on measured data sets. Generic Tier 2 tools for developing Exposure Scenarios do not exist yet. To enable efficient development of the worker exposure part of Exposure Scenarios a further development of Tier 1 and Tier 2 tools is needed. Special attention should be given to user friendliness and to the validity (boundaries) of the approaches. The development of standard worker exposure descriptions or full Exposure Scenarios by downstream user branches in cooperation with manufacturers and importers is recommended.","PeriodicalId":520670,"journal":{"name":"Journal of exposure science & environmental epidemiology","volume":" ","pages":"S16-25"},"PeriodicalIF":4.5,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/sj.jes.7500617","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41033413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

REACH epilogue. 到达尾声。

IF 4.5

Journal of exposure science & environmental epidemiology Pub Date : 2007-12-01 Epub Date: 2007-11-14 DOI: 10.1038/sj.jes.7500596

J I M Bridges

引用次数: 2