Journal of clinical hypertension (Greenwich, Conn.)最新文献

Early Carotid Structural and Functional Changes Associated With Elevated Blood Pressure in Children: A Multimodal Ultrasound Study. 儿童高血压相关的早期颈动脉结构和功能改变：一项多模态超声研究。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70271

Hui Wang, Yuanyuan Sheng, Xueyuan Lin, Ying Guo, Miaoru Yu, Youping Wang, Jie You, Jinfeng Xu, Yingying Liu

{"title":"Early Carotid Structural and Functional Changes Associated With Elevated Blood Pressure in Children: A Multimodal Ultrasound Study.","authors":"Hui Wang, Yuanyuan Sheng, Xueyuan Lin, Ying Guo, Miaoru Yu, Youping Wang, Jie You, Jinfeng Xu, Yingying Liu","doi":"10.1111/jch.70271","DOIUrl":"https://doi.org/10.1111/jch.70271","url":null,"abstract":"Childhood hypertension is closely associated with cardiovascular disease in adulthood, and the carotid artery is one of the principal target organs affected by elevated blood pressure (BP). The purpose of this study is to assess the association between carotid ultrasound-derived indices and elevated BP in children and to identify early vascular changes using multimodal ultrasound imaging. This case-control observational study included 118 children aged 10-11 years, of whom 55 had elevated BP and 63 had normal BP. Carotid ultrasound measurements included carotid diameter, conventional carotid intima-media thickness (CIMT), ultrahigh frequency CIMT (uhf-CIMT), carotid intima thickness, carotid media thickness (CMT), intima-to-media ratio (I/M), and radiofrequency-derived pulse wave velocity (rf-PWV). Associations between ultrasound parameters and BP were evaluated using multivariate linear regression models adjusted for age, sex, and body mass index. Children with elevated BP had higher values of uhf-CIMT, CMT, rf-PWV and lower values of I/M compared with children with normal BP (all p < 0.05). Systolic BP with the strongest association observed for CMT (r = 0.45). After adjustment for potential confounders, elevated BP remained independently associated with CMT, uhf-CIMT, I/M, and rf-PWV (all p < 0.05). Rf-PWV was significantly associated with carotid structural indices, particularly the I/M ratio (p < 0.05). Elevated BP in children is associated with early carotid structural remodeling and increased arterial stiffness. Ultrahigh frequency ultrasound may facilitate the detection of subtle vascular changes in pediatric with elevated BP.","PeriodicalId":520663,"journal":{"name":"Journal of clinical hypertension (Greenwich, Conn.)","volume":"28 5","pages":"e70271"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Success Rate of Adrenal Venous Sampling and the Location of Right Adrenal Vein Orifice: A Retrospective Study. 肾上腺静脉取样成功率及右肾上腺静脉口位置的回顾性研究。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70185

Min-Fu Bai, Jia-Jia Dong, Xiao-Mo Yang, Xiao-Hui Wang, Yong-Mei Liu, Chuan-Yu Gao, Qiu-Ping Zhao

{"title":"Success Rate of Adrenal Venous Sampling and the Location of Right Adrenal Vein Orifice: A Retrospective Study.","authors":"Min-Fu Bai, Jia-Jia Dong, Xiao-Mo Yang, Xiao-Hui Wang, Yong-Mei Liu, Chuan-Yu Gao, Qiu-Ping Zhao","doi":"10.1111/jch.70185","DOIUrl":"https://doi.org/10.1111/jch.70185","url":null,"abstract":"Adrenal venous sampling (AVS) is the gold standard for identifying aldosterone-producing adenoma and bilateral adrenal hyperplasia. This study reports the success rate of AVS and the distribution characteristics of the right adrenal vein orifice (RAVO). The data of 166 patients with primary hyperaldosteronism who underwent AVS in Fuwai Central China Cardiovascular Hospital were retrospectively reviewed. A single experienced cardiologist with 8 years of experience in cardiovascular intervention performed AVS on the included patients and separately drew 3 mL of blood from each adrenal vein and inferior vena cava. Successful catheterization was confirmed by cortisol ratio (the ratio of the cortisol concentration of each adrenal vein to that of the peripheral vein), and the distribution characteristics of the RAVO were recorded. The success rates of right and left blood samplings were 91.0% and 94.6%, respectively. The success rate of bilateral blood samplings was 86.1%. The success of right blood samplings was higher in patients with a higher body mass index (p = 0.03). The 151 patients whose right blood samplings were successful were divided into five groups according to RAVO location. In 130 (86.1%) of the 151 patients, the RAVO was located at a level ranging from the upper segment of T11 to the lower segment of T12. Age and serum creatinine levels showed statistical significance among the five groups (p = 0.001). These findings provide a practical anatomical roadmap for operators, suggesting that focusing the initial search for the RAVO between T11 and T12, especially in younger and heavier patients, could improve cannulation efficiency and success rates.","PeriodicalId":520663,"journal":{"name":"Journal of clinical hypertension (Greenwich, Conn.)","volume":"28 5","pages":"e70185"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

24-Hour Ambulatory Blood Pressure Monitoring during Ramadan Fasting: A Three-Year Cross-Sectional Study From a Tertiary Medical Center in Turkey. 斋月禁食期间24小时动态血压监测：土耳其三级医疗中心三年横断面研究

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70265

Mustafa Celik, Muhammed Fatih Kaleli, Mertcan Gezer, Nuraiym Moloshova, Meltem Uyaner Kan, Emirhan Feyzullahoglu, Serhat Kesriklioglu

{"title":"24-Hour Ambulatory Blood Pressure Monitoring during Ramadan Fasting: A Three-Year Cross-Sectional Study From a Tertiary Medical Center in Turkey.","authors":"Mustafa Celik, Muhammed Fatih Kaleli, Mertcan Gezer, Nuraiym Moloshova, Meltem Uyaner Kan, Emirhan Feyzullahoglu, Serhat Kesriklioglu","doi":"10.1111/jch.70265","DOIUrl":"10.1111/jch.70265","url":null,"abstract":"Ramadan fasting involves prolonged daily abstinence from food and water and may affect blood pressure (BP) regulation, particularly in individuals with chronic conditions. Evidence focusing specifically on ambulatory BP characteristics during Ramadan remains limited. This study evaluated 24-hour ambulatory BP monitoring (ABPM) parameters obtained during Ramadan in fasting and non-fasting individuals. In this prospective cross-sectional study, 231 adults underwent 24-hour ABPM during Ramadan between 2021 and 2023. Participants were classified as fasting or non-fasting and as hypertensive or non-hypertensive. Demographic characteristics, comorbidities, laboratory findings, and echocardiographic parameters were recorded. Ambulatory BP values were analyzed for 24-hour, daytime, and nighttime periods. Of the participants, 117 were fasting and 114 were non-fasting. Baseline demographic characteristics and cardiovascular comorbidities were similar between groups, although diabetes mellitus (DM) and chronic kidney disease (CKD) were more frequent in non-fasting individuals. No significant differences were observed in 24-hour or daytime systolic and diastolic BP values. Mean nighttime BP was lower in fasting participants (p = 0.032). Echocardiographic parameters were comparable. Fasting individuals had higher serum albumin levels (p = 0.027) and lower neutrophil counts (p = 0.030), while other biochemical markers did not differ significantly. Ramadan fasting was not associated with adverse ambulatory BP changes in hypertensive or normotensive individuals and may be considered safe in appropriately selected patients with well-controlled hypertension (HT).","PeriodicalId":520663,"journal":{"name":"Journal of clinical hypertension (Greenwich, Conn.)","volume":"28 5","pages":"e70265"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to the Comment on "Effect of Modular Training on Self-Management, Disease, and Treatment Adaptation in Individuals With Hypertension". 对“模块化培训对高血压患者自我管理、疾病和治疗适应的影响”评论的回应

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70268

Esra Keşer, Derya Atik, Ulviye Özcan Yüce

引用次数: 0

Reversible Neurological Manifestations Preceding Biochemical Deterioration in Postpartum HELLP Syndrome-A Case Report and Literature Review. 产后HELLP综合征生化恶化前的可逆性神经学表现——1例报告及文献复习。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70267

Dario Colacurci, Stefano Raffaele Giannubilo, Laura Sarno, Caterina Fulgione, Laura Letizia Mazzarelli, Angelo Sirico, Maria Liberata Meccariello, Andrea Albanese, Dayana Quintili, Irene Lubinski, Mario Ascione, Carla Riccardi, Giorgia D'Apice, Mariarosaria Motta, Sara Iannantuoni, Chiara Murolo, Giuseppe Bifulco, Costantino Di Carlo, Andrea Ciavattini, Giuseppe Maria Maruotti

{"title":"Reversible Neurological Manifestations Preceding Biochemical Deterioration in Postpartum HELLP Syndrome-A Case Report and Literature Review.","authors":"Dario Colacurci, Stefano Raffaele Giannubilo, Laura Sarno, Caterina Fulgione, Laura Letizia Mazzarelli, Angelo Sirico, Maria Liberata Meccariello, Andrea Albanese, Dayana Quintili, Irene Lubinski, Mario Ascione, Carla Riccardi, Giorgia D'Apice, Mariarosaria Motta, Sara Iannantuoni, Chiara Murolo, Giuseppe Bifulco, Costantino Di Carlo, Andrea Ciavattini, Giuseppe Maria Maruotti","doi":"10.1111/jch.70267","DOIUrl":"https://doi.org/10.1111/jch.70267","url":null,"abstract":"Posterior reversible encephalopathy syndrome (PRES) is a rare but severe neurological complication associated with hypertensive disorders of pregnancy and HELLP syndrome. We report a postpartum case in which neurological manifestations preceded the full biochemical expression of HELLP syndrome. A 22-year-old primigravida was admitted at 36 + 0 weeks for premature rupture of membranes and fetal growth restriction, presenting with mild thrombocytopenia and elevated lactate dehydrogenase but normal liver enzymes. On postpartum day 1, she developed headache, visual disturbances, hypertensive crisis, and a generalized tonic-clonic seizure. Brain magnetic resonance imaging revealed bilateral cortical-subcortical T2/FLAIR hyperintensities consistent with PRES. At that time, laboratory findings were not yet diagnostic of HELLP syndrome; however, by postpartum day 3, severe thrombocytopenia and elevated transaminases confirmed the diagnosis. The patient was treated with magnesium sulfate, antihypertensive therapy, corticosteroids, and plasmapheresis, achieving complete clinical and radiological recovery. A narrative review of the literature indicated that neurological manifestations typically occur within 48 h postpartum. This case highlights that PRES may precede the full laboratory expression of HELLP syndrome and underscores the importance of early recognition, prompt neuroimaging, and multidisciplinary management to ensure favorable maternal outcomes.","PeriodicalId":520663,"journal":{"name":"Journal of clinical hypertension (Greenwich, Conn.)","volume":"28 5","pages":"e70267"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond "One-Size-Fits-All": Deconstructing the Hormonal Determinants of Sodium Sensitivity in Treated Hypertension. 超越“一刀切”：解构高血压治疗中钠敏感性的激素决定因素。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70266

Dae-Hee Kim

引用次数: 0

Associations of Cumulative Burden of Prehypertension, Prediabetes and Predyslipidemia With All-Cause and Cardiovascular Disease Mortality: A Retrospective Cohort Study. 高血压前期、糖尿病前期和血脂异常前期累积负担与全因和心血管疾病死亡率的关联：一项回顾性队列研究

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70264

Jiao Meng, Gang Wang, Wei Wang, Junnan Wu

{"title":"Associations of Cumulative Burden of Prehypertension, Prediabetes and Predyslipidemia With All-Cause and Cardiovascular Disease Mortality: A Retrospective Cohort Study.","authors":"Jiao Meng, Gang Wang, Wei Wang, Junnan Wu","doi":"10.1111/jch.70264","DOIUrl":"10.1111/jch.70264","url":null,"abstract":"We aimed to examine the individual and combined impact of prehypertension, prediabetes, and predyslipidemia on all-cause and cardiovascular disease (CVD) mortality in community-dwelling adults. A retrospective cohort study of 11 986 US adults from the 1999-2018 National Health and Nutrition Examination Survey was conducted. Participants were categorized into four mutually exclusive groups based on the cumulative number of these conditions. Multivariate Cox proportional hazards models were applied to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality outcomes. The prevalences of no, one, two, and all three preclinical conditions were 37.20%, 38.39%, 19.86%, and 4.55%, respectively. Over a median follow-up of 10 years, 636 (3.83%) deaths occurred, including 170 (26.73%) from CVD. In a dose-response manner, the adjusted HRs (95%CIs) for all-cause mortality among those with one, two, and three conditions were 1.87 (1.38-2.52), 2.49 (1.80-3.44), and 2.62 (1.76-3.90), respectively, compared to those with none. The corresponding HRs (95%CIs) for CVD mortality were 3.09 (1.66-5.78), 3.89 (2.06-7.36), and 4.20 (2.04-8.69), respectively. Thus, an increasing cumulative number of preclinical conditions is associated with graded elevated risk of all-cause and CVD mortality, underscoring the potential for early intervention during the preclinical phase to improve long-term health outcomes.","PeriodicalId":520663,"journal":{"name":"Journal of clinical hypertension (Greenwich, Conn.)","volume":"28 5","pages":"e70264"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Effect of Modular Training on Self-Management, Disease, and Treatment Adaptation in Individuals With Hypertension: A Randomized Controlled Trial". 评论“模块化训练对高血压患者自我管理、疾病和治疗适应的影响：一项随机对照试验”。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70272

Noor Fatima, Eman Fatima

引用次数: 0

Potential Value of Weight-Adjusted Waist Circumference Index in Estimating the Prevalence of Prehypertension and Hypertension in an Elderly Chinese Population. 体重调整腰围指数在估计中国老年人群高血压前期和高血压患病率中的潜在价值。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70270

Ruoyu Zhu, Zhi Du, Xuanhan Lin, Zhuolin Wang, Xiaogang Guo

{"title":"Potential Value of Weight-Adjusted Waist Circumference Index in Estimating the Prevalence of Prehypertension and Hypertension in an Elderly Chinese Population.","authors":"Ruoyu Zhu, Zhi Du, Xuanhan Lin, Zhuolin Wang, Xiaogang Guo","doi":"10.1111/jch.70270","DOIUrl":"https://doi.org/10.1111/jch.70270","url":null,"abstract":"To determine the correlation between weight-adjusted-waist index (WWI) with prehypertension and hypertension in the general population. This cross-sectional study was conducted from September 13, 2023 to November 30, 2023 and included 4885 permanent residents in Zhejiang Province. The association between WWI with prehypertension and hypertension was carefully evaluated using logistic regression models and penalized spline functions. The category-free analysis was performed to corroborate whether WWI enhanced the ability to estimate prehypertension and hypertension. Multivariable logistic regression indicated that after adjustment for conventional risk factors, each standard deviation increase in WWI levels was associated with a 29% and 50% increased risk of prehypertension (hazard ratio, 1.29; 95% confidence interval, 1.14-1.45) and hypertension (1.50; 1.34-1.68), respectively. Referring to the participants in the lowest quartile of WWI, those in the highest quartile had a significantly increased risk of prehypertension (1.64; 1.17-2.30) and hypertension (2.47; 1.80-3.39). Smoothing curve fitting and trend logistic regression suggested a linear positive correlation, and the robustness of these findings was observed in interaction tests and subgroup analyses. The category-free analysis suggested that adding WWI levels to the traditional model ultimately improved the predictive ability of prehypertension and hypertension. The results of this study confirmed the significant correlation between WWI with prehypertension and hypertension, independent of conventional risk factors. More importantly, these findings suggested the potential usefulness of WWI levels to improve the risk stratification of hypertension and prehypertension.","PeriodicalId":520663,"journal":{"name":"Journal of clinical hypertension (Greenwich, Conn.)","volume":"28 5","pages":"e70270"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "Hypertensive Disorders of Pregnancy and Midlife Maternal Cognition in a Prospective Cohort Study". 更正“妊娠期高血压疾病与中年产妇认知的前瞻性队列研究”。

IF 2.5

Journal of clinical hypertension (Greenwich, Conn.) Pub Date : 2026-05-01 DOI: 10.1111/jch.70273

引用次数: 0