Infection & chemotherapy最新文献

{"title":"Aseptic Meningitis Following Second Dose of an mRNA Coronavirus Disease 2019 Vaccine in a Healthy Male: Case Report and Literature Review.","authors":"Han Sol Kang,&nbsp;Ju Eun Kim,&nbsp;Jeong Rae Yoo,&nbsp;Hyunjoo Oh,&nbsp;Misun Kim,&nbsp;Young Ree Kim,&nbsp;Sang Taek Heo","doi":"10.3947/ic.2021.0131","DOIUrl":"https://doi.org/10.3947/ic.2021.0131","url":null,"abstract":"<p><p>Vaccines are one of the most important strategies against pandemics or epidemics involving infectious diseases. With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there have been global efforts for rapid development of coronavirus disease 2019 (COVID-19) vaccine and vaccination is being performed globally on a massive scale. With rapid increase in vaccination, rare adverse events have been reported. Well-known neurological adverse events associated with COVID-19 vaccination include Guillain-Barré syndrome, myelitis, and encephalitis. However, COVID-19 vaccine-related aseptic meningitis has rarely been reported. A 32-year-old healthy man visited our hospital with a complaint of headache for 1 week. He had received the second dose of the BNT162b2 mRNA COVID-19 vaccine 2 weeks before the onset of headache. Since the initial cerebrospinal fluid (CSF) profile suggested viral meningitis, we started treatment with an antiviral agent. However, the symptoms and follow-up CSF profile on day 7 of hospitalization showed no improvement and SARS-CoV-2 IgG antibodies were detected in the CSF. We suspected aseptic meningitis associated with the vaccination and intravenous methylprednisolone (500 mg/day) was administered for 3 days. The symptoms improved and the patient was discharged on day 12 of hospitalization.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"189-194"},"PeriodicalIF":4.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/e1/ic-54-189.PMC8987175.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39775063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiologically Suspected Organizing Pneumonia in a Patient Recovering from COVID-19: A Case Report.","authors":"Hyeonji Seo,&nbsp;Jiwon Jung,&nbsp;Min Jae Kim,&nbsp;Se Jin Jang,&nbsp;Sung-Han Kim","doi":"10.3947/ic.2021.0013","DOIUrl":"https://doi.org/10.3947/ic.2021.0013","url":null,"abstract":"<p><p>We report a case of coronavirus disease 2019 (COVID-19)-associated radiologically suspected organizing pneumonia with repeated negative Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) results from nasopharyngeal swab and sputum samples, but positive result from bronchoalveolar lavage fluid. Performing SARS-CoV-2 RT-PCR in upper respiratory tract samples only could fail to detect COVID-19-associated pneumonia, and SARS-CoV-2 could be an etiology of radiologically suspected organizing pneumonia.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"208-212"},"PeriodicalIF":4.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9c/4c/ic-54-208.PMC8987187.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39155404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of African Tick-Bite Fever in a Returning Traveler from Southern Africa.","authors":"Woonji Lee,&nbsp;Hye Seong,&nbsp;Jung Ho Kim,&nbsp;Heun Choi,&nbsp;Jun Hyoung Kim,&nbsp;Jin Young Ahn,&nbsp;Su Jin Jeong,&nbsp;Nam Su Ku,&nbsp;Jun Yong Choi,&nbsp;Choon-Mee Kim,&nbsp;Dong-Min Kim,&nbsp;Joon-Sup Yeom","doi":"10.3947/ic.2019.0073","DOIUrl":"https://doi.org/10.3947/ic.2019.0073","url":null,"abstract":"<p><p>African tick-bite fever (ATBF), caused by <i>Rickettsia africae</i>, is the second most frequent cause of fever after malaria in travelers returning from Southern Africa. As the Korean outbound travelers are increasing every year, tick-borne rickettsial diseases as a cause of febrile illness are likely to increase. We describe a febrile Korean returning traveler who showed two eschars after visiting the rural field in Manzini, Swaziland. We performed nested polymerase chain reaction using the eschar and diagnosed the patient with ATBF. He was treated with oral doxycycline for 7 days, and recovered without any complications. We believe that the present case is the first ATBF case diagnosed in a Korean traveler.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"202-207"},"PeriodicalIF":4.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b5/07/ic-54-202.PMC8987174.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38241568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Support of Ethnopharmacological Practices: Exploring a Long-Term Solution for the Prevention and Treatment of COVID-19 in the Philippines.","authors":"Dalmacito A Cordero","doi":"10.3947/ic.2022.0002","DOIUrl":"https://doi.org/10.3947/ic.2022.0002","url":null,"abstract":"Several efforts are initiated worldwide regarding the rapid search for potential coronavirus disease 2019 (COVID-19) treatment. In a recent article published in this journal, the authors affirmed this continuous search for therapeutic options and they presented ruxolitinib as a potential treatment approach for severe COVID-19 [1]. In relation to this, developing countries such as the Philippines faces a big challenge concerning this endeavor since the government are having a difficult time in purchasing such medicines due to complicated policies for imported drugs, lack of funds, public’s fear of the drugs’ side effects, and even delay in delivery. With this, I suggest that the facilitation of ethnopharmacological approaches must be explored. The discovering and testing of other “safer” alternatives, with lesser side effects, may cause a big difference in developing an effective response to the disease. This may also address vaccine hesitancy as well as solve the problem of vaccine/drug unavailability and delivery since they will be produced locally. Thus, the government must give equal priority and full support to a plant-based intervention. The country still depends on the technological advancement from other nations that is why all the vaccines/drugs are imported abroad. However, it is important to note that the Philippines is renowned as one of the species-rich countries with regard to medicinal plants. This reality can pave way for the development of a “homegrown” vaccine/drug which will not only be economically helpful but will address the interconnected problems mentioned.","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"176-177"},"PeriodicalIF":4.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/ca/ic-54-176.PMC8987180.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39775064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumonia due to <i>Schizophyllum commune</i> in a Patient with Acute Myeloid Leukemia: Case Report and Literature Review.","authors":"Hahn Kim,&nbsp;Yunmi Yi,&nbsp;Sung-Yeon Cho,&nbsp;Dong-Gun Lee,&nbsp;Hye-Sun Chun,&nbsp;Chulmin Park,&nbsp;Yoo-Jin Kim,&nbsp;Yeon-Joon Park","doi":"10.3947/ic.2020.0068","DOIUrl":"https://doi.org/10.3947/ic.2020.0068","url":null,"abstract":"<p><p><i>Schizophyllum commune</i> is a mold in phylum Basidiomycota and is an uncommon human pathogen. Sinusitis and allergic bronchopulmonary mycosis are the two major diseases caused by <i>S. commune</i>. Although there have been several reports of invasive fungal diseases, most of them were invasive sinusitis. We present a case of invasive fungal pneumonia due to <i>S. commune</i>, developed in a patient with acute myeloid leukemia presenting neutropenic fever. The diagnosis was made by characteristic macroscopic and microscopic findings of fungal isolate and was confirmed via sequencing of internal transcribed spacer region. The patient was improved after 8 weeks of antifungal therapy based on the susceptibility result. We propose that <i>S. commune</i> should be considered as an emerging pathogen of invasive fungal pneumonia when a patient is under immunocompromised state. We also reviewed global literatures focused on the invasive fungal diseases caused by <i>S. commune</i>.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"195-201"},"PeriodicalIF":4.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/40/ic-54-195.PMC8987182.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38547309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Resistance Patterns of <i>Enterobacteriaceae</i> Isolated from Patients with Healthcare-Associated Infections.","authors":"Young Kyun Choi,&nbsp;Eun Ju Byeon,&nbsp;Jin Ju Park,&nbsp;Jacob Lee,&nbsp;Yu Bin Seo","doi":"10.3947/ic.2021.0030","DOIUrl":"https://doi.org/10.3947/ic.2021.0030","url":null,"abstract":"<p><strong>Background: </strong>There have been recent proposals to categorize healthcare-associated infections (HCAIs) separately from community-acquired infections (CAIs). The aim of this study was to compare the antibiotic resistance of pathogens causing CAIs, HCAIs, and hospital-acquired infections (HAIs) in Korea, and to investigate the need for different empirical antibiotics therapy for CAIs and HCAIs.</p><p><strong>Materials and methods: </strong>This prospective study was conducted in a university hospital between March and December 2019. Inpatients who underwent a bacterial culture within 2 days of hospitalization, with a <i>Enterobacteriaceae</i> strain identified at the infection site and available antibiotic susceptibility results, were included in the analysis. Infections were classified as CAIs, HCAIs or HAIs, depending on the source.</p><p><strong>Results: </strong>Of the 146 patients included in the analysis, the prevalence of fluoroquinolone-resistant <i>Enterobacteriaceae</i> was 18.8%, 38.5%, and 55.0%; the prevalence of pathogens showing third-generation cephalosporins resistance was 8.3%, 50.0%, and 60.0%; and the prevalence of pathogens showing piperacillin-tazobactam resistance was 8.3%, 7.7%, 15.0% in the CAIs, HCAIs, and HAIs groups, respectively. The prevalence of extended-spectrum beta-lactamase-positive pathogens was 6.3%, 47.3%, and 55.0% in the CAIs, HCAIs, and HAIs group, respectively, with no significant difference between the HCAIs and HAIs groups. Resistance patterns of the HCAIs group more closely resembled those of the HAIs group than those of the CAIs group.</p><p><strong>Conclusion: </strong>The pathogens isolated from patients with HCAIs showed resistance patterns that were more similar to those of patients with HAIs than those with CAIs. Thus, CAIs and HCAIs should be distinguished from each other when selecting antibiotic agents.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"355-363"},"PeriodicalIF":4.2,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/d9/ic-53-355.PMC8258300.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39145076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Fatal Case of Bacteremia Caused by <i>Vibrio cholerae</i> Non-O1/O139.","authors":"Soyoon Hwang,&nbsp;Yoonjung Kim,&nbsp;Hyejin Jung,&nbsp;Hyun Ha Chang,&nbsp;Su Jeong Kim,&nbsp;Han Ki Park,&nbsp;Jong Myung Lee,&nbsp;Hye In Kim,&nbsp;Shin Woo Kim","doi":"10.3947/ic.2020.0301","DOIUrl":"https://doi.org/10.3947/ic.2020.0301","url":null,"abstract":"<p><p><i>Vibrio cholerae</i> is a pathogen known to cause the waterborne epidemic disease cholera. Overall, <i>V. cholerae</i> O1 or O139 strains produce the cholera toxin that cause gastroenteritis, resulting in watery diarrhea. Most of the enterocolitis caused by <i>V. cholerae</i> can be easily treated with fluid therapy and conservative care. However, <i>V. cholerae</i> non-O1/O139 strains can cause extraintestinal infections, such as wound infection or sepsis, in immunocompromised patients. The clinical course of these infections is very similar to that of <i>V. vulnificus</i> infection. We report about a 52-year-old man without previous underlying disease who was diagnosed with <i>V. cholerae</i> non-O1/O139 infection and died within 72 hours after admission to the intensive care unit.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"384-390"},"PeriodicalIF":4.2,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/77/e5/ic-53-384.PMC8258294.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38330207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nosocomial Outbreak of COVID-19 in a Hematologic Ward.","authors":"Jiwon Jung,&nbsp;Jungmin Lee,&nbsp;Seongmin Jo,&nbsp;Seongman Bae,&nbsp;Ji Yeun Kim,&nbsp;Hye Hee Cha,&nbsp;Young Ju Lim,&nbsp;Sun Hee Kwak,&nbsp;Min Jee Hong,&nbsp;Eun Ok Kim,&nbsp;Joon Yong Bae,&nbsp;Changmin Kang,&nbsp;Minki Sung,&nbsp;Man Seong Park,&nbsp;Sung Han Kim","doi":"10.3947/ic.2021.0046","DOIUrl":"https://doi.org/10.3947/ic.2021.0046","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus disease 2019 (COVID-19) outbreaks occur in hospitals in many parts of the world. In hospital settings, the possibility of airborne transmission needs to be investigated thoroughly.</p><p><strong>Materials and methods: </strong>There was a nosocomial outbreak of COVID-19 in a hematologic ward in a tertiary hospital, Seoul, Korea. We found 11 patients and guardians with COVID-19 through vigorous contact tracing and closed-circuit television monitoring. We found one patient who probably had acquired COVID-19 through airborne-transmission. We performed airflow investigation with simulation software, whole-genome sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).</p><p><strong>Results: </strong>Of the nine individuals with COVID-19 who had been in the hematologic ward, six stayed in one multi-patient room (Room 36), and other three stayed in different rooms (Room 1, 34, 35). Guardian in room 35 was close contact to cases in room 36, and patient in room 34 used the shared bathroom for teeth brushing 40 minutes after index used. Airflow simulation revealed that air was spread from the bathroom to the adjacent room 1 while patient in room 1 did not used the shared bathroom. Airflow was associated with poor ventilation in shared bathroom due to dysfunctioning air-exhaust, grill on the door of shared bathroom and the unintended negative pressure of adjacent room.</p><p><strong>Conclusion: </strong>Transmission of SARS-CoV-2 in the hematologic ward occurred rapidly in the multi-patient room and shared bathroom settings. In addition, there was a case of possible airborne transmission due to unexpected airflow.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"332-341"},"PeriodicalIF":4.2,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d7/04/ic-53-332.PMC8258301.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39145074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue Virus is Hyperendemic in Nigeria from 2009 to 2020: A Contemporary Systematic Review.","authors":"Anthony Uchenna Emeribe,&nbsp;Idris Nasir Abdullahi,&nbsp;Idongesit Kokoabasi Isong,&nbsp;Anthony Ogbonna Emeribe,&nbsp;Justin Onyebuchi Nwofe,&nbsp;Buhari Isa Shuaib,&nbsp;Abubakar Muhammad Gwarzo,&nbsp;Yahaya Usman,&nbsp;Madjid Sadi,&nbsp;Chikodi Modesta Umeozuru,&nbsp;Amos Dangana,&nbsp;Bibiana Nonye Egenti,&nbsp;Mala Alhaji Baba Mallam,&nbsp;Abigail Uchenna Emelonye,&nbsp;Maijiddah Saidu Aminu,&nbsp;Hadiza Yahaya,&nbsp;Silifat Oyewusi","doi":"10.3947/ic.2020.0142","DOIUrl":"https://doi.org/10.3947/ic.2020.0142","url":null,"abstract":"<p><strong>Backround: </strong>Data on Dengue virus (DENV) infection prevalence, geographic distribution and risk factors are necessary to direct appropriate utilization of existing and emerging control strategies. This study aimed to determine the pooled prevalence, risk factors of DENV infection and the circulating serotypes within Nigeria from January 1, 2009 to December 31, 2020.</p><p><strong>Materials and methods: </strong>Twenty-one studies out of 2,215 available articles were eligible and included for this systematic review. Relevant articles were searched, screened and included in this study according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) criteria. The risk of bias in primary studies was assessed by Cochrane's method. Heterogeneity of pooled prevalence was calculated using the chi-square test on Cochrane's Q statistic, which was quantified by I-square values. The random-effects analyses of proportions were used to determine the pooled prevalence of DENV antibodies, antigen and RNA from eligible studies.</p><p><strong>Results: </strong>Of these, 3 studies reported co-circulation of all the 4 serotypes, while 2 separately reported co-circulation of DENV-1 &2 and DENV-1 to -3. All the antibody-based studies had significantly high heterogeneity (I² >90%, <i>P</i> <0.05), while the NS1 and PCR-based studies had low heterogeneity (I² <25%, <i>P</i> >0.05). The pooled prevalence of DENV IgM, IgG, RNA, NS1 and neutralizing antibodies were 16.8%, 34.7%, 7.7%, 7.7% and 0.7%, respectively. South-east Nigeria had the highest pooled DENV-IgG seropositivity, 77.1%. Marital status, gender, educational level and occupation status, the proximity of residence to refuse dumpsite, frequent use of trousers and long sleeve shirts were significantly associated with DENV IgG seropositivity (<i>P</i> <0.05).</p><p><strong>Conclusion: </strong>Based on these findings, it can be inferred that Nigeria is hyperendemic for Dengue fever and needs concerted efforts to control its spread within and outside the country.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"284-299"},"PeriodicalIF":4.2,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/2b/ic-53-284.PMC8258289.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39145070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Analysis of the Serovars and Antibiogram of <i>Vibrio cholerae</i> Isolates of the 2017 Ilorin Cholera Outbreak, Nigeria.","authors":"Dele Ohinoyi Amadu,&nbsp;Idris Nasir Abdullahi,&nbsp;Ezekiel Seibu,&nbsp;Abayomi Fadeyi,&nbsp;Khadeejah Kamaldeen,&nbsp;Aliu Ajibola Akanbi,&nbsp;Chukwudi Crescent Okwume,&nbsp;Motunrayo Bukola Amadu,&nbsp;Charles Nwabuisi","doi":"10.3947/ic.2021.0001","DOIUrl":"https://doi.org/10.3947/ic.2021.0001","url":null,"abstract":"<p><p>In this retrospective study, we determined the incidence, serovars, and antibiogram of <i>Vibrio cholerae</i> isolated from 102 clinical stool samples collected from rice water diarrheic patients during an outbreak (May - July 2017) in Ilorin metropolis, Nigeria. The culture positive rate of the <i>V. cholerae</i> isolates was 41.2%, with 41 and 1 isolates from O1 (Inaba) and non-O1/O139 serogroups, respectively. The isolates were the most susceptible to ciprofloxacin (76.2%) followed by amoxicillin-clavulanate (71.4%). However, all isolates were resistant to ampicillin and tetracycline. In conclusion, <i>V. cholerae</i> O1 was the predominant circulating serogroup exhibiting multi-drug resistance during the outbreak.</p>","PeriodicalId":520645,"journal":{"name":"Infection & chemotherapy","volume":" ","pages":"368-373"},"PeriodicalIF":4.2,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/6d/ic-53-368.PMC8258287.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39064763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}