Nusrat Mahmud, Eshita Sharmin, Md Arif Mamun, Zayan Shamayeen, Natalie Rivadeneira, Roger Rochat, Akanksha Mehta
{"title":"Decline in semen parameters from 2000 to 2016 among Bangladeshi men attending a tertiary care hospital.","authors":"Nusrat Mahmud, Eshita Sharmin, Md Arif Mamun, Zayan Shamayeen, Natalie Rivadeneira, Roger Rochat, Akanksha Mehta","doi":"10.4103/iju.IJU_30_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_30_17","url":null,"abstract":"<p><strong>Introduction: </strong>The objective of this study was to analyze longitudinal changes in sperm parameters of Bangladeshi men. We hypothesized that semen parameters declined for this population.</p><p><strong>Methods: </strong>We retrospectively analyzed semen data from men aged 18-64 years who sought care for general sperm quality or updates on fertility status at an infertility clinic in Dhaka, Bangladesh, from January 2000 to June 2016 (<i>n</i> = 13,953). Samples with incomplete data were excluded (<i>n</i> = 143). The WHO normal criteria and semen analysis procedures were used to evaluate parameters of the remaining 13,810 specimens. Samples with missing values on sperm concentration (<i>n</i> = 6187) were excluded from concentration analyses. Age and duration of abstinence at testing were recorded and adjusted for. Data were imported into SAS<sup>®</sup> 9.4 statistical software. Temporal significance was investigated using one-way ANOVA for motility parameters and Chi-square test for raw concentration. Logistic regression analyzed the effects of confounders on azoospermia and raw concentration, while median regression modeling adjusted confounders for concentration, total motility, and rapid linear (RL) motility.</p><p><strong>Results: </strong>Age distribution was significantly correlated with annual parameter changes (concentration, total motility, and RL motility [<i>P</i> < 0.0001]). Adjusted total motility and RL motility declined by 20% from their maximum values to end of the study (<i>P</i> < 0.0001). Raw concentration lacked clear trends and was unaffected by adjustment. Azoospermia increased by 18% between the 2000-2010 and 2011-2016 participants (odds ratio = 0.16 [0.14-0.16]).</p><p><strong>Conclusion: </strong>In agreement with the hypothesis, Bangladeshi males attending this clinic have experienced decline in semen parameters (total motility and RL motility) and increased frequency of azoospermia.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"28-33"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4d/cd/IJU-34-28.PMC5769245.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35744313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IJU Awards 2017.","authors":"","doi":"10.4103/iju.IJU_368_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_368_17","url":null,"abstract":"","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"93-94"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/44/21/IJU-34-93.PMC5769265.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35744775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Reply Re: Goel A. Research training during residency. Indian J Urol 2017;33:257-8.","authors":"Apul Goel","doi":"10.4103/iju.IJU_366_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_366_17","url":null,"abstract":"The author mistakenly feels that while mentioning Indian work on chyluria, a significant work on povidone‐iodine instillation published in the British Journal of Urology in 2004 was omitted.[1] We simply aimed to highlight that research on chyluria has been scant from India, especially when India contributes to 40% of the global burden of lymphatic filariasis.[2] To justify this statement, giving examples of 2016 and 2017, we mentioned that only a handful of articles were published on this topic from India. We do not mention anything about 2004 or the many other articles that have been published from India on chyluria in the last many years.","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"90-91"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/15/IJU-34-90.PMC5769263.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35744776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric pelvic fracture urethral distraction defect causing complete urethrovaginal avulsion.","authors":"Ritesh Kumar Singh, Devashish Kaushal, Nikhil Khattar, Rishi Nayyar, T Manasa, Rajeev Sood","doi":"10.4103/iju.IJU_118_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_118_17","url":null,"abstract":"<p><p>Pelvic fracture with urethral injury in girls is an uncommon entity that is usually associated with concomitant vaginal lacerations. Management options vary from immediate exploration and urethral anastomosis to delayed urethroplasty. We report our experience of managing a 10-year old girl presenting 6 months after a pelvic fracture with urethrovaginal injury and a completely obliterated urethral meatus managed successfully with a single-stage bladder tube repair.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"76-78"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6c/da/IJU-34-76.PMC5769256.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35744770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manoj K Sudrania, Anuj Deep Dangi, Santosh Kumar, Barath Kumar, Nitin S Kekre
{"title":"Urodynamic outcomes of tamsulosin in the treatment of primary bladder neck obstruction in men.","authors":"Manoj K Sudrania, Anuj Deep Dangi, Santosh Kumar, Barath Kumar, Nitin S Kekre","doi":"10.4103/iju.IJU_123_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_123_17","url":null,"abstract":"<p><strong>Introduction: </strong>Alpha blockers are widely used in the treatment of primary bladder neck obstruction; however, evidence for objective urodynamic efficacy is scarce. We studied the effect of the uroselective α1-blocker tamsulosin on urodynamic parameters in male patients with type I primary bladder neck obstruction.</p><p><strong>Methods: </strong>A single center prospective observational study was carried out from July 2013 to February 2015. Male patients (18-50 years) with type 1 primary bladder neck obstruction were recruited. Selected patients were started on tablet tamsulosin 0.4 mg once daily for 3 months. International prostate symptom score (IPSS), uroflow and urodynamic studies were done pre- and post-treatment. Primary outcome was decreased in minimum detrusor pressure at maximum flow rate by 15%. Wilcoxon-matched pair signed-rank test was used.</p><p><strong>Results: </strong>Of 39 patients recruited, 21 patients completed the follow-up as per protocol and were analyzed. Mean age was 41 years. 57% patients achieved the primary outcome (median detrusor pressure pre- and post-treatment were 71 and 56 cm of water, <i>P</i> < 0.001). Similarly, median values for bladder outlet obstruction index (BOOI) and IPSS decreased from 59 to 38 (<i>P</i> < 0.001) and 22 to 12 (<i>P</i> < 0.001), respectively. Median maximum flow rate increased from 8 to 10 ml (<i>P</i> = 0.05). Pretreatment BOOI of >60 was associated with poor outcomes.</p><p><strong>Conclusions: </strong>Tamsulosin 0.4 mg once a day is effective in reducing bladder outlet obstruction on pressure flow studies in patients with primary bladder neck obstruction type 1.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"34-38"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/9f/IJU-34-34.PMC5769247.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35745923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suprava Naik, Arashdeep Singh, Sudipta Mohakud, Nerbadyswari Deep
{"title":"Periureteral inferior vena caval venous ring presenting as urinary obstruction.","authors":"Suprava Naik, Arashdeep Singh, Sudipta Mohakud, Nerbadyswari Deep","doi":"10.4103/iju.IJU_98_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_98_17","url":null,"abstract":"<p><p>The embryological development of the inferior vena cava (IVC) is complex, and thus the vena cava may undergo a large number of congenital anomalies. Periureteric venous ring is a rare developmental anomaly of IVC where the right ureter passes through a slit-like opening in a partially duplicated infrarenal IVC, resulting in dilatation of upper urinary tract. Split-bolus multidetector computed tomography technique is useful in detecting such vascular anomaly causing ureteric obstruction as it can clearly show the vascular and ureteric phase in a single acquisition.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"87-88"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/75/IJU-34-87.PMC5769260.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35744777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kareem N Rayn, Graham R Hale, Gustavo Pena-La Grave, Piyush K Agarwal
{"title":"New therapies in nonmuscle invasive bladder cancer treatment.","authors":"Kareem N Rayn, Graham R Hale, Gustavo Pena-La Grave, Piyush K Agarwal","doi":"10.4103/iju.IJU_296_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_296_17","url":null,"abstract":"<p><strong>Introduction: </strong>Nonmuscle invasive bladder cancer (NMIBC) remains a very challenging disease to treat with high rates of recurrence and progression associated with current therapies. Recent technological and biological advances have led to the development of novel agents in NMIBC therapy.</p><p><strong>Methods: </strong>We reviewed existing literature as well as currently active and recently completed clinical trials in NMIBC by querying PubMed.gov and clinicaltrials.gov.</p><p><strong>Results: </strong>A wide variety of new therapies in NMIBC treatment are currently being developed, utilizing recent developments in the understanding of immune therapies and cancer biology.</p><p><strong>Conclusion: </strong>The ongoing efforts to develop new therapeutic approaches for NMIBC look very promising and are continuing to evolve.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"11-19"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/4d/IJU-34-11.PMC5769243.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35745924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Jian Wei Gan, Jaslyn Ju Lia Gan, Jasmine Ju Hsien Gan, Kim Tiong Lee
{"title":"Lateral percutaneous nephrolithotomy: A safe and effective surgical approach.","authors":"Jonathan Jian Wei Gan, Jaslyn Ju Lia Gan, Jasmine Ju Hsien Gan, Kim Tiong Lee","doi":"10.4103/iju.IJU_219_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_219_17","url":null,"abstract":"<p><strong>Introduction: </strong>Percutaneous nephrolithotomy (PCNL) is traditionally performed with the patient in the prone position for large renal calculi. However, anesthetic limitations exist with the prone position. Similarly, the supine position is associated with poorer ergonomics due to the awkward downward position of the renal tract, a smaller window for percutaneous puncture, and a higher risk of anterior calyx puncture. This study aimed to demonstrate the feasibility and safety of lateral-PCNL in managing large renal calculi without the disadvantages of prone and supine positions.</p><p><strong>Methods: </strong>Retrospectively, 347 lateral-PCNL cases performed from July 2001 to July 2015 were examined. the patient's thorax, abdomen, and pelvis were positioned over a bridge perpendicular to a \"broken\" table, creating an extended lumbodorsal space. The procedure was evaluated in terms of stone clearance at 3 months' postprocedure, operative time, and complications.</p><p><strong>Results: </strong>Primary stone clearance was achieved in 82.7% of patients. The mean operating time was 97 min. The average time taken to establish the tract and mean radiation time were 4.5 min and 6.93 min, respectively. In total, 2.3% of patients required postoperative transfusion, and 13.5% of patients had postoperative fever. There was one case of hydrothorax, but no bowel perforation.</p><p><strong>Conclusions: </strong>Our lateral-PCNL technique allows for effective stone clearance due to good stone ergonomics and it should be considered as a safe alternative even in the most routine procedures.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"45-50"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/14/IJU-34-45.PMC5769249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35745925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aditya P Sharma, Ravimohan Suryanarayana Mavuduru, Girdhar Singh Bora, Sudheer K Devana, Kiruthika Palani, Anupam Lal, Nandita Kakkar, Shrawan K Singh, Arup K Mandal
{"title":"Comparison of RENAL, PADUA, and C-index scoring systems in predicting perioperative outcomes after nephron sparing surgery.","authors":"Aditya P Sharma, Ravimohan Suryanarayana Mavuduru, Girdhar Singh Bora, Sudheer K Devana, Kiruthika Palani, Anupam Lal, Nandita Kakkar, Shrawan K Singh, Arup K Mandal","doi":"10.4103/iju.IJU_247_17","DOIUrl":"https://doi.org/10.4103/iju.IJU_247_17","url":null,"abstract":"<p><strong>Introduction and objective: </strong>The RENAL, PADUA and centrality index (C-index) nephrometry scoring systems (SS) have been individually evaluated for their role in predicting trifecta outcomes after nephron-sparing surgery (NSS). However, there is little data on their comparative superiority. The present study was designed to evaluate the predictive value of three SS and to assess interobserver reliability.</p><p><strong>Materials and methods: </strong>Fifty patients undergoing NSS at our center between January 2014 and April 2016 were included in the study. The demographic details were noted. Images (computed tomography [CT] scans or magnetic resonance imaging) were reviewed by a urologist and a radiologist independently and RENAL, PADUA, and C-index were calculated. The correlation between these scoring system and trifecta outcomes were calculated.</p><p><strong>Results: </strong>The RENAL and PADUA score did not correlate with any of the perioperative parameters. However, C-index had a significant correlation with operative time (OT) (<i>P</i> = 0.02) and trifecta outcomes (<i>P</i> < 0.05). There was an excellent concordance between the two observers in scoring the RENAL score (α = 0.915; intraclass correlation coefficient [ICC] = 0.814) and PADUA score (α = 0.816; ICC = 0.689 [<i>P</i> < 0.001]). There was lesser although acceptable concordance in the calculation of C-index (ICC -0.552; α -0.711).</p><p><strong>Conclusions: </strong>There is good correlation among all the 3 SS. C-index has lower reproducibility due to difficult mathematical calculation but correlated best with trifecta outcomes.</p>","PeriodicalId":520644,"journal":{"name":"Indian journal of urology : IJU : journal of the Urological Society of India","volume":" ","pages":"51-55"},"PeriodicalIF":1.1,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1f/2f/IJU-34-51.PMC5769250.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35745927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}