K Li, A Wen, J Bai, M Xu, T Ma, D Wang, Y Zhao, B Xia
{"title":"Three-dimensional morphological evaluation of anatomical models for 101 primary maxillary central incisors.","authors":"K Li, A Wen, J Bai, M Xu, T Ma, D Wang, Y Zhao, B Xia","doi":"10.1007/s40368-025-01058-x","DOIUrl":"https://doi.org/10.1007/s40368-025-01058-x","url":null,"abstract":"<p><strong>Purpose: </strong>Research on primary maxillary central incisors (PMCIs) remains limited, and their morphological variations have rarely been documented. This study aimed to reconstruct anatomy of PMCIs in children from Beijing (China) and to analyse their commonalities and variations.</p><p><strong>Methods: </strong>Employing a threshold-based semi-automated region segmentation method, anatomical models of 101 PMCIs were reconstructed from existing cone-beam computed tomography (CBCT) images. Models were classified according to the Vertucci classification. For each variant type, representative morphological parameters of the hard tissue, pulp chamber, and canals were measured. The type with the highest prevalence was selected as the main type and its average model was constructed, representing the most common characteristics of PMCIs.</p><p><strong>Results: </strong>All PMCIs had a single root, whereas novel canal variations were identified. The most common canal type was Type I (61.4%), followed by Type V (20.8%) and Type III (17.8%). Anatomical parameters of main-type PMCIs were as follows: hard-tissue length = 15.76 ± 0.89 mm; pulp chamber and canal length = 12.94 ± 1.15 mm; and apical labial curvature angle was 22.57°. Statistical analysis indicated no differences between left and right, and no sex-related differences (p > 0.05). Statistically significant differences between the main-type and other variants were noted for several pulp-chamber and canal measurements (p < 0.05), but not for hard-tissue measurements (p > 0.05). An average main-type model was constructed; its inner and outer profiles conformed to the general characteristics of main-type PMCIs.</p><p><strong>Conclusion: </strong>PMCI canal variations were more complex than previously recognised, with uniform hard-tissue anatomy. Furthermore, an average main-type model was constructed, as a potentially valuable tool for dental education.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Babasidou, G Papaemmanouil, A Pantelidou, A Fardi, K Kodonas, C Gogos
{"title":"Selective caries removal and management of exposed pulp in fully developed and immature teeth with reversible pulpitis: a questionnaire-based study in Greece.","authors":"E Babasidou, G Papaemmanouil, A Pantelidou, A Fardi, K Kodonas, C Gogos","doi":"10.1007/s40368-025-01024-7","DOIUrl":"10.1007/s40368-025-01024-7","url":null,"abstract":"<p><strong>Purpose: </strong>Guidelines recommend implementing selective or total caries removal for managing deep carious lesions without discriminating between fully developed and immature teeth. This questionnaire-based study aimed to explore the perspectives of Greek dentists regarding the management of deep caries and exposed pulp in immature and fully developed teeth with reversible pulpitis.</p><p><strong>Methods: </strong>The questionnaire presented two cases: one of a fully developed permanent tooth and one of an immature permanent tooth, both with deep caries and clinical signs of reversible pulpitis. Photographs, radiographs, and clinical symptoms were provided to assess dentists' treatment strategy preferences. Data analysis was conducted using SPSS 28, Chi-square, Fisher's exact tests and logistic regression analysis with significance set at p < 0.05.</p><p><strong>Results: </strong>A total of 453 dentists responded. More than half of the respondents preferred total caries removal for mature teeth. MTA and other bioceramics emerged as the favored materials for indirect and direct pulp capping. In the case of the immature tooth, 44% of the respondents shifted from the total to selective caries removal treatment option. However, there was a discernible shift towards more aggressive vital pulp treatment options, like pulpotomy (26%).</p><p><strong>Conclusion: </strong>Treatment preferences are influenced by the tooth developmental status, vary significantly and there is no clear preference for a more conservative approach to preserving as much healthy pulp tissue as possible.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":"559-570"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Bani-Hani, M Wedyan, R Al-Fodeh, R Shuqeir, S Al Jundi, N Tewari
{"title":"Artificial intelligence model for application in dental traumatology.","authors":"T Bani-Hani, M Wedyan, R Al-Fodeh, R Shuqeir, S Al Jundi, N Tewari","doi":"10.1007/s40368-025-01063-0","DOIUrl":"https://doi.org/10.1007/s40368-025-01063-0","url":null,"abstract":"<p><strong>Background: </strong>In recent years, healthcare systems have witnessed a tremendous advancement in diagnostic tools and technologies. The advent of artificial intelligence (AI) has enabled a paradigm shift in the practice of health sciences particularly in medicine. In the dental field, AI has been scarcely used in the various disciplines with no application in dental traumatology. This study proposes a deep-learning, convolutional neural networks (CNN)-based model for detection and classification of dental fractures.</p><p><strong>Methods: </strong>Plain periapical radiographs of injured teeth were retrieved from patients' records and annotated by two dentists trained in dental traumatology. The teeth were categorised into four groups: uncomplicated crown fractures, complicated crown fractures, crown-root fractures and root fractures. Data augmentation was done to enhance the power of the current dataset. Images were divided into training (80%) and test (20%) datasets. Python programming language was used to implement the CNN-based classification model. Cross validation was applied.</p><p><strong>Results: </strong>A total of 72 plain periapical radiographs of 108 fractured teeth were collected. The model achieved high accuracy in differentiating uncomplicated crown fractures from complicated ones (96.0%), from crown-root fractures (99.1%) and from root fractures (98.7%). Furthermore, the complicated injuries were distinguished from crown-root fractures and from root fractures with accuracy levels at 96.3% and 97.2% respectively. The model's overall accuracy in recognising the four classes was 78.7%.</p><p><strong>Conclusion: </strong>The proposed model showed excellent performance in the classification of dental fractures. The application of AI in paediatric dentistry, particularly in the field of dental trauma, is innovative and highly relevant to current trends in healthcare technology. Expansion of the current model to a larger dataset that includes the various types of injuries is recommended in future research. Such models can be a great asset for the less-experienced dentists in making accurate diagnosis and timely decisions. Future models employing panoramic radiographs could also help the medical practitioners at emergency services.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Singh, A Goyal, M Luthra-Guptasarma, A Kapur, M Jaiswal, S Madan
{"title":"A proteomics approach to understand the hypomineralisation of second primary molars (HSPM). In-vitro study.","authors":"A Singh, A Goyal, M Luthra-Guptasarma, A Kapur, M Jaiswal, S Madan","doi":"10.1007/s40368-025-01032-7","DOIUrl":"https://doi.org/10.1007/s40368-025-01032-7","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was a proteomic investigation of test enamel of HSPM vs the control enamel of Second Primary Molars, to gain an insight into the possible mechanism of pathogenesis of hypomineralisation.</p><p><strong>Methods: </strong>Enamel sample blocks were sectioned and processed for label-free quantitation of proteins by LC-MS/MS, followed by bioinformatics analyses of differentially expressed proteins (DEP); two DEPs were validated by western/dot blot.</p><p><strong>Results: </strong>There was a significant elevation of total number of proteins in the HSPM samples as compared to the control enamel. A significant elevation of proteins such as protein LEG1 homolog, Odontogenesis-associated phosphoprotein, Leucocyte elastase inhibitor, Olfactomedin-like protein 3 and albumin were observed in HSPM-affected enamel, along with upregulation of calcium-binding proteins and immunoglobulins. Evaluation of signalling pathways contributed by the upregulated proteins in HSPM enamel samples was suggestive of increased levels of different components of the immune (defence) system such as raised antibodies (immunoglobulins level), complement coagulation cascade activation, neutrophil and platelet degranulation as well as defence response to bacteria/ fungus.</p><p><strong>Conclusions: </strong>The study results suggest the possibility of an underlying infectious/inflammatory aetiology responsible for hypomineralisation of primary enamel in these patients. Such a proteomics approach is useful to guide preventive interventions for HSPM.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effective anaesthesia when treating teeth affected by molar incisor hypomineralisation (MIH): a systematic review.","authors":"Miniar Rhaiem, Marwa Chatti, Yamina Elelmi, Aymen Ben Haj Khalifa, Fatma Masmoudi, Ahlem Baaziz","doi":"10.1007/s40368-025-01057-y","DOIUrl":"https://doi.org/10.1007/s40368-025-01057-y","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the present review was to critically evaluate recent studies to determine the optimal combination of anaesthetic technique and agent for achieving effective anaesthesia in molar incisor hypomineralisation (MIH) patients, thereby addressing a significant need in evidence-based clinical practice. The search question was: What is the most effective modality of anaesthesia to reduce hypersensitivity in MIH-affected teeth in children?</p><p><strong>Methods: </strong>A systematic search was conducted using four databases, namely, MEDLINE via PubMed, Science Direct, Scopus and Cochrane Central Register of Controlled Trials (CENTRAL), using a selection of MeSH terms. The \"Modified Jadad Scale\" and the \"Newcastle Ottawa Scale\" were used for the methodology assessment of the included studies.</p><p><strong>Results: </strong>Out of 134 articles identified in the initial search, six articles met all the inclusion criteria. The results showed that intraosseous anaesthesia with 4% articaine demonstrated the highest efficacy.</p><p><strong>Conclusion: </strong>Achieving complete anaesthesia in teeth affected by MIH enhances comfort for both patients and practitioners, contributing to improved treatment quality. Intraosseous anaesthesia with 4% articaine and epinephrine has proven effective in reducing pain and hypersensitivity in pediatric patients with MIH. However, further studies are needed in this population to draw definitive conclusions.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T R Leal, L J Serafim de Araújo, M de França Perazzo, É T Barbosa Neves, F R Ortiz, M C Gomes, A F Granville-Garcia
{"title":"Association of dental caries, family cohesion, and orofacial dysfunction in children aged 8 to 10 with possible sleep bruxism: pathway analysis.","authors":"T R Leal, L J Serafim de Araújo, M de França Perazzo, É T Barbosa Neves, F R Ortiz, M C Gomes, A F Granville-Garcia","doi":"10.1007/s40368-025-01059-w","DOIUrl":"https://doi.org/10.1007/s40368-025-01059-w","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present study was to explore the association of dental caries, family cohesion, and orofacial dysfunction in children 8-10 years of age with sleep bruxism. A school-based analytical cross-sectional study was conducted involving 739 school children in a medium-sized city in Brazil.</p><p><strong>Materials and methods: </strong>The parents/guardians answered a socioeconomic questionnaire and the Family Adaptability and Cohesion Assessment Scale (FACES III). The children reported whether they had experienced bullying in the previous 30 days. The diagnosis of possible sleep bruxism (PSB) was based on the reports of parents/guardians. Four trained examiners (Kappa > 0.80) diagnosed cavitated carious lesions using the International Caries Detection and Assessment System and administered the Nordic Orofacial Test-Screening to investigate orofacial dysfunction. Data analysis involved structural equation modelling. The direct and indirect associations between the variables of the theoretical model were determined through the calculation of standardised coefficients and goodness-of-fit indices.</p><p><strong>Result: </strong>The cavitated lesions (path coefficient [PC]: -0.23; p < 0.01) and family cohesion (PC: 0.13; p < 0.01) exerted a direct influence on the prevalence of PSB. Family income exerted an indirect influence on PSB, exerting a direct influence on cavitated lesions (PC: 0.24; p < 0.01) and family cohesion (PC: 0.217; p < 0.01). Bullying and orofacial dysfunction were not significantly associated with PSB.</p><p><strong>Conclusion: </strong>In conclusion, cavitated carious lesions and low family cohesion exerted a direct influence on the occurrence of PSB. Family income had an indirect effect, whilst bullying and orofacial dysfunction had no influence on the outcome.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Root anatomy and canal configuration of primary molars: a systematic review and meta-analysis\".","authors":"A Mathur, R Sah","doi":"10.1007/s40368-025-01067-w","DOIUrl":"https://doi.org/10.1007/s40368-025-01067-w","url":null,"abstract":"","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Audio sensory methods in oral hygiene maintenance.","authors":"M Farrokhi, K Harati","doi":"10.1007/s40368-025-01055-0","DOIUrl":"https://doi.org/10.1007/s40368-025-01055-0","url":null,"abstract":"","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144130032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A scoping review of proteomic alterations in molar-incisor hypomineralisation: insights from enamel and salivary composition.","authors":"G Sivaramakrishnan, K Sridharan","doi":"10.1007/s40368-025-01050-5","DOIUrl":"https://doi.org/10.1007/s40368-025-01050-5","url":null,"abstract":"<p><strong>Objectives: </strong>The aetiology and treatment of molar-incisor hypomineralisation (MIH) may be further investigated by understanding the proteomic changes associated with the defect. The present scoping review aimed to systematically examine existing literature on salivary and enamel proteomics related to MIH, characterising specific proteins associated with the defect and evaluating methodologies employed in current proteomic studies.</p><p><strong>Methods: </strong>The review was conducted following the PRISMA-ScR guidelines. A systematic search of PUBMED, SCOPUS, EMBASE, Web of Science, and Cochrane databases was performed for clinical trials and observational studies published until February 2025. Inclusion criteria encompassed studies on human samples examining proteomics related to MIH with a control group. Two reviewers independently screened articles for eligibility.</p><p><strong>Results: </strong>Six studies met the inclusion criteria. Key findings revealed significant alterations in protein composition in MIH-affected enamel and saliva, including proteins, such as chitinase 1, human serum albumin, collagen alpha 1 (I), collagen alpha 2 (I), alpha-1-antitrypsin, and dentin sialophosphoprotein (DSPP). In particular, MIH samples exhibited overexpression of proteins linked to inflammation and stress responses, including albumin, fibrinogen, and complement C3. Proteomic analyses highlighted the potential of salivary and enamel proteins as biomarkers for MIH, although variations in research methodologies presented challenges in establishing standardised biomarkers.</p><p><strong>Conclusions: </strong>This review underscores the importance of proteomic analysis in understanding the molecular mechanisms underlying MIH. Identifying specific proteins may enhance diagnostic and therapeutic strategies for affected children. However, substantial research gaps remain, particularly in the exploration of various proteomic sources and the dynamic nature of salivary proteins.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144130029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eruptive movements of ectopic permanent mandibular canines: a case series study based on serial orthopantomograms from ten children with unilateral ectopia and six children with bilateral ectopia.","authors":"I Kjær, M Svanholt, P Svanholt","doi":"10.1007/s40368-025-01049-y","DOIUrl":"https://doi.org/10.1007/s40368-025-01049-y","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this study is to evaluate the patterns of eruptive movements of ectopic mandibular canines observed on series of orthopantomograms from each individual. The hypothesis is that the eruption direction might be predicted from the location and morphology of the permanent canine.</p><p><strong>Material and methods: </strong>Radiographic material was forwarded from orthodontic colleagues in Denmark and the Nordic countries. In 16 cases/individuals with unilateral or bilateral mandibular canine ectopia, more than one orthopantomogram from each individual was forwarded. The material consists of 41 radiographs from these 16 individuals. In each, the primary mandibular canine existed in the first taken orthopantomogram. The radiographs were taken with the same radiographic equipment, but not necessarily with the same settings and patient orientation. The material was divided according to unilateral ectopia (10 individuals) and bilateral ectopia (6 individuals), and according to the initial location of the permanent canine, compared to the axis of the primary canine (Ax) in the posterior location and anterior location. The following were registered: ages, lengths of age interval between orthopantomograms, canine maturity, root morphology, crown morphology, and location of permanent canines expressed in distances and angles.</p><p><strong>Results: </strong>The following were concluded. Ectopia was diagnosed earlier in bilateral cases (about 9 years of age) than in unilateral cases (about 12 years of age). More radiographs were taken for each child in the bilateral group, compared to the unilateral group. Extraction of the primary canines occurred often in the bilateral group, but seldom in the unilateral group. The posteriorly located unilateral ectopic canine was located further posterior, compared to the Ax, than bilateral cases. The crown morphology changed during the eruption movements. Curved root morphology appeared in the bilateral cases. Three different patterns were registered in canine eruption (upward, downward, and anterior movements), seemingly dependent on the location and crown morphology of the permanent canine. In bilateral cases, the eruption deviation was most severe on the left side.</p><p><strong>Conclusion: </strong>There are considerable differences between unilateral and bilateral ectopic permanent mandibular canines. The differences are predominantly in the age of the children when ectopia is diagnosed, the number of orthopantomograms taken, and furthermore the location, crown morphology and eruptive movements of the ectopic permanent mandibular canine.</p>","PeriodicalId":520615,"journal":{"name":"European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}