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Causes of varied internal echo patterns in ultrasound imaging of breast lymphoma. 乳腺淋巴瘤超声显像内回声变化的原因分析。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-04-07 DOI: 10.1007/s12282-025-01820-5
Yumi Kokubu, Tomo Osako, Takehiko Sakai, Yui Tomita, Chieko Kato, Yuri Maruoka, Masashi Akiya, Chikako Takahata, Takayuki Ueno, Kiyoshi Matsueda
{"title":"Causes of varied internal echo patterns in ultrasound imaging of breast lymphoma.","authors":"Yumi Kokubu, Tomo Osako, Takehiko Sakai, Yui Tomita, Chieko Kato, Yuri Maruoka, Masashi Akiya, Chikako Takahata, Takayuki Ueno, Kiyoshi Matsueda","doi":"10.1007/s12282-025-01820-5","DOIUrl":"10.1007/s12282-025-01820-5","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"582-592"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of xeno-free induced mesenchymal stem/stromal cells in enhancing autologous fat graft survival. 无xeno诱导间充质干细胞/基质细胞提高自体脂肪移植存活的效果。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI: 10.1007/s12282-026-01838-3
Hideharu Nakamura, Takaya Makiguchi, Takahiro Yamaguchi, Sasagu Kurozumi, Daisuke Kamiya, Makoto Ikeya, Takaaki Fujii, Akihiko Uchiyama, Sei-Ichiro Motegi, Jun Horiguchi, Ken Shirabe, Satoshi Yokoo
{"title":"Efficacy of xeno-free induced mesenchymal stem/stromal cells in enhancing autologous fat graft survival.","authors":"Hideharu Nakamura, Takaya Makiguchi, Takahiro Yamaguchi, Sasagu Kurozumi, Daisuke Kamiya, Makoto Ikeya, Takaaki Fujii, Akihiko Uchiyama, Sei-Ichiro Motegi, Jun Horiguchi, Ken Shirabe, Satoshi Yokoo","doi":"10.1007/s12282-026-01838-3","DOIUrl":"10.1007/s12282-026-01838-3","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"612-624"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic significance of peripheral myeloid-derived suppressor cells in advanced breast cancer. 外周血髓源性抑制细胞在晚期乳腺癌中的预后意义。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI: 10.1007/s12282-026-01831-w
Haruka Kanaoka, Masayuki Nagahashi, Junko Tsuchida, Mamiko Kuroiwa, Sayaka Urano, Miki Komatsu, Shoko Yoshida, Aoi Oshiro, Gen Sugimoto, Ayumu Mitsuyoshi, Yusa Togashi, Akira Hattori, Tomoko Higuchi, Arisa Nishimukai, Masafumi Shimoda, Yasuo Miyoshi
{"title":"Prognostic significance of peripheral myeloid-derived suppressor cells in advanced breast cancer.","authors":"Haruka Kanaoka, Masayuki Nagahashi, Junko Tsuchida, Mamiko Kuroiwa, Sayaka Urano, Miki Komatsu, Shoko Yoshida, Aoi Oshiro, Gen Sugimoto, Ayumu Mitsuyoshi, Yusa Togashi, Akira Hattori, Tomoko Higuchi, Arisa Nishimukai, Masafumi Shimoda, Yasuo Miyoshi","doi":"10.1007/s12282-026-01831-w","DOIUrl":"10.1007/s12282-026-01831-w","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"601-611"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of HER2, HER3, and TROP2 in primary tumors and brain metastases of breast cancer. 乳腺癌原发肿瘤和脑转移灶中HER2、HER3和TROP2的表达
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-03-13 DOI: 10.1007/s12282-026-01841-8
S Kusuhara, T Kogawa, M Shimokawa, C Funasaka, C Kondoh, K Harano, N Matsubara, Y Naito, A Hosono, K Satomi, M Yoshida, S Fujii, T Onishi, A Suto, K Yonemori, K Koyama, R Nakamura, N Maeda, Y Narita, T Mukohara
{"title":"Expression of HER2, HER3, and TROP2 in primary tumors and brain metastases of breast cancer.","authors":"S Kusuhara, T Kogawa, M Shimokawa, C Funasaka, C Kondoh, K Harano, N Matsubara, Y Naito, A Hosono, K Satomi, M Yoshida, S Fujii, T Onishi, A Suto, K Yonemori, K Koyama, R Nakamura, N Maeda, Y Narita, T Mukohara","doi":"10.1007/s12282-026-01841-8","DOIUrl":"10.1007/s12282-026-01841-8","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"644-652"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147461477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in re-excision rates after publication of guidelines defining positive margins for breast-conserving surgery: a collaborative study of the Japanese breast cancer society. 日本乳腺癌协会的一项合作研究：确定保乳手术阳性切缘的指南发表后再切除率的变化。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-04-08 DOI: 10.1007/s12282-026-01853-4
Takehiko Sakai, Yuri Kimura, Makoto Ishitobi, Atsushi Yoshida, Yasuaki Sagara, Yuka Ono, Koji Takada, Yuko Takahashi, Takahiro Tsukioki, Mao Kimoto, Tomo Osako
{"title":"Changes in re-excision rates after publication of guidelines defining positive margins for breast-conserving surgery: a collaborative study of the Japanese breast cancer society.","authors":"Takehiko Sakai, Yuri Kimura, Makoto Ishitobi, Atsushi Yoshida, Yasuaki Sagara, Yuka Ono, Koji Takada, Yuko Takahashi, Takahiro Tsukioki, Mao Kimoto, Tomo Osako","doi":"10.1007/s12282-026-01853-4","DOIUrl":"10.1007/s12282-026-01853-4","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"761-769"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solamargin-functionalized gold nanoparticles codelivering photothermal-immunotherapy for triple-negative breast cancer. 太阳边缘功能化金纳米粒子协同提供光热免疫治疗三阴性乳腺癌。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-04-01 DOI: 10.1007/s12282-026-01849-0
Zhengwei Gui, Lu Zhao, Shiyang Liu, Lin Zhang
{"title":"Solamargin-functionalized gold nanoparticles codelivering photothermal-immunotherapy for triple-negative breast cancer.","authors":"Zhengwei Gui, Lu Zhao, Shiyang Liu, Lin Zhang","doi":"10.1007/s12282-026-01849-0","DOIUrl":"10.1007/s12282-026-01849-0","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"705-721"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PIK3CA mutation in ER-negative and HER2-positive breast cancer with apocrine differentiation. PIK3CA突变在er阴性和her2阳性乳腺癌与大汗腺分化。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-02-23 DOI: 10.1007/s12282-026-01837-4
Fumi Nozaki, Yoko Nakanishi, Yukari Hirotani, Hiroko Kobayashi, Tomoyuki Tanino, Haruna Nishimaki-Watanabe, Sumie Ohni, Xiaoyan Tang, Shinobu Masuda
{"title":"PIK3CA mutation in ER-negative and HER2-positive breast cancer with apocrine differentiation.","authors":"Fumi Nozaki, Yoko Nakanishi, Yukari Hirotani, Hiroko Kobayashi, Tomoyuki Tanino, Haruna Nishimaki-Watanabe, Sumie Ohni, Xiaoyan Tang, Shinobu Masuda","doi":"10.1007/s12282-026-01837-4","DOIUrl":"10.1007/s12282-026-01837-4","url":null,"abstract":"<p><strong>Background: </strong>Targeted therapies for PIK3CA-mutated breast cancer are currently limited to the hormone receptor (HR)-positive and HER2-negative subtype. Carcinoma with apocrine differentiation (apocrine ca.) is typically characterized as ER-negative and HER2-positive/negative. Consequently, patients with apocrine ca. are generally excluded from PIK3CA genotyping and targeted therapies, even when mutations are present. Here, we investigated the prevalence and functional significance of PIK3CA mutations in apocrine ca., particularly in ER-negative (HER2-subtypes and triple-negative) subtypes.</p><p><strong>Methods: </strong>We analyzed hotspot PIK3CA mutations in apocrine ca. and invasive breast carcinoma of no special type (IBC-NST) (20 and 70 samples, respectively). PIK3CA knockdown was performed to compare the proliferation of breast cancer cell lines representing two types of apocrine ca. with PIK3CA mutations (MDA-MB-453: ER-/HER2+/AR + and MFM223: ER-/HER2-/AR+) and one without PIK3CA mutations (HCC1428: ER+/HER2-/AR-).</p><p><strong>Results: </strong>PIK3CA mutations occurred in apocrine ca. (3/20, 15.0%) and IBC-NST (2/70, 2.9%) cases (P = 0.071). Within the ER-negative and HER2-positive subtypes, PIK3CA mutations were present in 25% of apocrine ca. (2/8) cases, whereas no mutations were observed in positive IBC-NST (0/18) (P = 0.086). siRNA-mediated PIK3CA knockdown reduced the proliferation of MDA-MB-453 (P < 0.01) and MFM223 (P = 0.01) cells, whereas no effect was observed in HCC1428 cells (P = 0.674), relative to the non-targeting siRNA control.</p><p><strong>Conclusions: </strong>PIK3CA mutations are present in ER-negative and HER2-positive apocrine ca., and these mutations drive PIK3CA-dependent proliferation in vitro. These results suggest that patients with apocrine ca. may benefit from PIK3CA mutation testing and subsequent targeted therapy.</p>","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"625-633"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of sentinel lymph node biopsy versus axillary lymph node dissection on shoulder range of motion in early rehabilitation after breast cancer surgery. 前哨淋巴结活检与腋窝淋巴结清扫对乳腺癌术后早期康复肩关节活动度的影响。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-03-11 DOI: 10.1007/s12282-026-01827-6
Honami Hieda, Yasunori Umemoto, Aoi Aasaumi, Naoki Hashimoto, Makoto Yamagishi, Kai Ushio, Akimitsu Yamada, Takeshi Nakamura
{"title":"Impact of sentinel lymph node biopsy versus axillary lymph node dissection on shoulder range of motion in early rehabilitation after breast cancer surgery.","authors":"Honami Hieda, Yasunori Umemoto, Aoi Aasaumi, Naoki Hashimoto, Makoto Yamagishi, Kai Ushio, Akimitsu Yamada, Takeshi Nakamura","doi":"10.1007/s12282-026-01827-6","DOIUrl":"10.1007/s12282-026-01827-6","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"593-600"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early outcomes of accelerated partial breast irradiation and dosimetric comparison of volumetric modulated arc therapy and three-dimensional conformal radiotherapy. 加速部分乳房照射的早期结果及体积调制弧线治疗和三维适形放疗的剂量学比较。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-03-16 DOI: 10.1007/s12282-026-01844-5
Tomomi Aoshika, Nobue Uchida, Fumihiro Tomita, Ryohei Yamauchi, Reiko Kondo, Ayako Kurose, Junko Takei, Atsushi Yoshida, Satoshi Ishikura
{"title":"Early outcomes of accelerated partial breast irradiation and dosimetric comparison of volumetric modulated arc therapy and three-dimensional conformal radiotherapy.","authors":"Tomomi Aoshika, Nobue Uchida, Fumihiro Tomita, Ryohei Yamauchi, Reiko Kondo, Ayako Kurose, Junko Takei, Atsushi Yoshida, Satoshi Ishikura","doi":"10.1007/s12282-026-01844-5","DOIUrl":"10.1007/s12282-026-01844-5","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"675-682"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with central venous port implantation during breast cancer perioperative chemotherapy: a Japanese database study. 乳腺癌围手术期化疗期间中心静脉口植入的相关因素：一项日本数据库研究。
IF 2.9
Breast cancer (Tokyo, Japan) Pub Date : 2026-05-01 Epub Date: 2026-04-07 DOI: 10.1007/s12282-026-01850-7
Mari Abe, Kojiro Morita, Takaaki Konishi, Katsuhiko Nara, Yuya Kimura, Kiyohide Fushimi, Hideo Yasunaga, Gojiro Nakagami
{"title":"Factors associated with central venous port implantation during breast cancer perioperative chemotherapy: a Japanese database study.","authors":"Mari Abe, Kojiro Morita, Takaaki Konishi, Katsuhiko Nara, Yuya Kimura, Kiyohide Fushimi, Hideo Yasunaga, Gojiro Nakagami","doi":"10.1007/s12282-026-01850-7","DOIUrl":"10.1007/s12282-026-01850-7","url":null,"abstract":"","PeriodicalId":520574,"journal":{"name":"Breast cancer (Tokyo, Japan)","volume":" ","pages":"736-743"},"PeriodicalIF":2.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13124893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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