Pediatric discovery最新文献

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Sleep-related disorders in children: A narrative review. 儿童睡眠相关障碍:叙述性回顾。
Pediatric discovery Pub Date : 2024-04-27 eCollection Date: 2024-06-01 DOI: 10.1002/pdi3.76
Yogev Cohen, Joel Reiter, Alex Gileles-Hillel
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引用次数: 0
Pediatric heart failure classification based on left ventricular ejection fraction. 基于左心室射血分数的小儿心力衰竭分类。
Pediatric discovery Pub Date : 2023-12-27 eCollection Date: 2023-12-01 DOI: 10.1002/pdi3.50
Shan Huang, Xue Xiang, Xu Zhu, Jie Tian, Bo Pan, Min Zheng
{"title":"Pediatric heart failure classification based on left ventricular ejection fraction.","authors":"Shan Huang, Xue Xiang, Xu Zhu, Jie Tian, Bo Pan, Min Zheng","doi":"10.1002/pdi3.50","DOIUrl":"10.1002/pdi3.50","url":null,"abstract":"<p><p>Left ventricle ejection fraction (LVEF) is still not well acknowledged in classification of pediatric heart failure (PHF). We categorized PHF according to LVEF and aimed to determine the role of LVEF in PHF classification. Patients who were diagnosed with HF were divided into three groups according to their LVEF values: HF with reduced ejection fraction (HFrEF), HF with mildly reduced ejection fraction (HFmrEF), and HF with preserved ejection fraction (HFpEF). The clinical information of PHF patients was compared among those three groups. Factors associated with HF with improved EF (HFimpEF) and risk factors for in-hospital death in PHF patients were analyzed. A total number of 1228 cases were collected. The proportion of HF patients with preserved LVEF (66.3%) was significantly higher than those with mildly reduced LVEF (21.7%) and reduced LVEF (12%). Clinical features such as age, B-type natriuretic peptide (BNP) level, Ross classification, and E/A abnormal proportion in HF children with different LVEF value were statistically different. HF patients with younger age, lower BNP levels, minor cardiac dysfunction and less E/A abnormality could be found with higher LVEF value. The proportion of primary disease in PHF was largely different in HFpEF, HFmrEF and HFrEF groups. Medication treatment was more aggressive in patients with lower LVEF, except for vasoactive drugs. Children with congenital heart disease in HFrEF group were more prone to develop into HFimpEF. Sepsis, renal insufficiency, and an abnormal E/A ratio are risk factors for in-hospital death of HF children. Clinical features of PHF could be well classified by LVEF, which is an essential and helpful indicator for PHF classification and management.</p>","PeriodicalId":520221,"journal":{"name":"Pediatric discovery","volume":"1 3","pages":"e50"},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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