Frontiers in dementia最新文献

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Informed consent in dementia research: how Public Involvement can contribute to addressing "old" and "new" challenges. 痴呆研究中的知情同意:公众参与如何有助于应对“旧”和“新”挑战。
Frontiers in dementia Pub Date : 2025-02-04 eCollection Date: 2025-01-01 DOI: 10.3389/frdem.2025.1536762
Ana Diaz, Cindy Birck, Angela Bradshaw, Jean Georges, Daphne Lamirel, Soraya Moradi-Bachiller, Dianne Gove
{"title":"Informed consent in dementia research: how Public Involvement can contribute to addressing \"old\" and \"new\" challenges.","authors":"Ana Diaz, Cindy Birck, Angela Bradshaw, Jean Georges, Daphne Lamirel, Soraya Moradi-Bachiller, Dianne Gove","doi":"10.3389/frdem.2025.1536762","DOIUrl":"10.3389/frdem.2025.1536762","url":null,"abstract":"<p><p>Informed consent is a critical ethical requirement in research, ensuring the protection of participants' rights and promoting their wellbeing and autonomy. In dementia research, this process becomes particularly complex due to cognitive impairments and fluctuating capacity. While substantial work has been done to address these challenges, much of the literature on informed consent in dementia research has been shaped by the perspectives of researchers and healthcare professionals, with less focus on those with lived experience. This paper provides an overview of the perspectives of people with dementia and their carers resulting from Public Involvement activities organized by Alzheimer Europe. It builds on Alzheimer Europe's previous work with the European Working Group of People with Dementia and draws on discussions held during a face-to-face meeting about Participant Informed Consent forms and processes used in two specific European projects. We highlight views and key concerns raised by people with lived experience regarding the informed consent process, including barriers and facilitators. In addition to ensuring understandability, the discussions emphasized the importance of promoting respect and autonomy, ensuring that the values and interests of people with lived experience remain central throughout the research process. This paper contributes to the ongoing dialogue on improving informed consent practices in dementia research, highlighting the need for continuous involvement and the inclusion of people with lived experience in shaping consent practices to address both old and emerging challenges (i.e., new types of research such as artificial intelligence and data sharing/re-use) in dementia research.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"4 ","pages":"1536762"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Defining familiarity in nursing homes providing care for residents with dementia: a scoping review. 在为痴呆症患者提供护理的养老院中定义熟悉度:范围审查。
Frontiers in dementia Pub Date : 2025-02-03 eCollection Date: 2025-01-01 DOI: 10.3389/frdem.2025.1470066
Joanna Sun, Sumiyo Brennan, Therese Doan
{"title":"Defining familiarity in nursing homes providing care for residents with dementia: a scoping review.","authors":"Joanna Sun, Sumiyo Brennan, Therese Doan","doi":"10.3389/frdem.2025.1470066","DOIUrl":"10.3389/frdem.2025.1470066","url":null,"abstract":"<p><strong>Objective: </strong>This study explores the underpinning definitions associated with familiarity in the context of dementia inclusive design and nursing home environment.</p><p><strong>Background: </strong>Environmental design in nursing homes impacts the quality of life and care of residents with dementia. One of the key principles of design is the need for the environment to achieve a sense of familiarity. However, there are divergent perspectives regarding the term \"familiarity.\" Inconsistent definitions are challenging to understand, and they continue to impact the implementation of good design. To that end, this scoping review examines the definitions and associated with familiarity, dementia, and the design of nursing home environments.</p><p><strong>Methods: </strong>The Arksey and O'Malley methodological framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews ensure the rigor of the scoping review. Searches were conducted using six databases for peer-reviewed publications in English from 1991 to 2023. Search terms included \"dementia,\" \"nursing home,\" \"long-term care,\" \"familiar,\" \"familiarity,\" and \"environments.\"</p><p><strong>Results: </strong>The searches yielded 245 publications. Of those, 46 studies from 19 countries were included in this review. The review uncovered three central themes and compelling evidence citing the inclusion of homelike environments. Emphasis on design considerations includes the wellbeing of the designated population and the need to embrace multisensory integration in the design process.</p><p><strong>Conclusions: </strong>A strong link exists between familiarity and key design considerations, such as a homelike environment, wellbeing, and multisensory integration. These considerations can enhance the effectiveness of the design of familiar environments.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"4 ","pages":"1470066"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review. 研究痴呆中多动和精神病症状的神经病理学相关性:一项系统综述
Frontiers in dementia Pub Date : 2025-01-29 eCollection Date: 2025-01-01 DOI: 10.3389/frdem.2025.1513644
Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Ildebrando Marco Appollonio, Alfredo Costa, Tino Emanuele Poloni
{"title":"Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review.","authors":"Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Ildebrando Marco Appollonio, Alfredo Costa, Tino Emanuele Poloni","doi":"10.3389/frdem.2025.1513644","DOIUrl":"10.3389/frdem.2025.1513644","url":null,"abstract":"<p><strong>Introduction: </strong>Behavioral and Psychological Symptoms of Dementia (BPSD) are common neuropsychiatric manifestations that complicate the clinical course of dementia and impact caregiving. Among these, the Hyperactivity-Impulsivity-Irritiability-Disinhibition-Aggression-Agitation (HIDA) and Psychosis (P) domains are particularly challenging to manage. Despite their prevalence, their underlying mechanisms and neuropathological correlates, remain poorly understood. This systematic review aims to elucidate the neuropathological basis of the HIDA and psychosis domains, exploring whether distinct proteinopathies and neural circuit dysfunctions are associated with these symptoms.</p><p><strong>Methods: </strong>The review follows PRISMA guidelines, with a systematic search conducted across MEDLINE, CENTRAL, and EMBASE databases. Inclusion criteria involved studies exploring the neuropathology of the HIDA and psychosis domains in individuals with dementia. Records were screened using PICO software, and data quality was assessed using the Newcastle-Ottawa Scale (NOS) and CARE guidelines. A narrative synthesis was conducted due to heterogeneity in the data.</p><p><strong>Results: </strong>From 846 records identified, 37 studies met inclusion criteria. Of the 18,823 cases analyzed, the most common diagnoses were Alzheimer's Disease (83.44%), Dementia with Lewy Bodies (5.37%), and Frontotemporal Dementia (13.40%). HIDA-P symptoms were distributed across all clinical diagnoses, with agitation (14.00%), delusions (11.60%), disinhibition (7.61%), and hallucinations (6.83%) being the most frequently reported behaviors. The primary neuropathological diagnosis was Alzheimer's Disease Neuropathologic Change (ADNC), present predominantly in intermediate to severe forms. The neuropathological analysis revealed the co-occurrence of multiple proteinopathies, particularly TAUopathy, TDP-43 pathology, and Lewy-related pathology (LRP), with the latter, in association with ADNC, reported in 15 studies.</p><p><strong>Discussion: </strong>HIDA-P symptoms were linked with overlapping involvement of different neural circuits, particularly the amygdala and the broader limbic system. Evidence suggests that TAUopathy and multiple proteinopathies in key brain regions, such as amygdala, are central to the development of these symptoms. In contrast, the contribution of beta-amyloid and vascular damage appears marginal in the genesis of HIDA and psychotic symptoms. No behavioral symptom is pathognomonic of a specific proteinopathy; rather, the topography and severity of lesions plays a more decisive role than their single molecular composition.</p><p><strong>Systematic review registration: </strong>INPLASY2024100082.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"4 ","pages":"1513644"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11814221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities. 激素替代疗法、绝经年龄和生活方式变量与随访时更好的认知表现相关,但与老年成年妇女的认知能力无关,而与APOE4携带者状态和合并症无关。
Frontiers in dementia Pub Date : 2025-01-17 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1496051
Tamlyn J Watermeyer, Sarah Gregory, Emmi Leetham, Chinedu T Udeh-Momoh, Graciela Muniz-Terrera
{"title":"Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities.","authors":"Tamlyn J Watermeyer, Sarah Gregory, Emmi Leetham, Chinedu T Udeh-Momoh, Graciela Muniz-Terrera","doi":"10.3389/frdem.2024.1496051","DOIUrl":"10.3389/frdem.2024.1496051","url":null,"abstract":"<p><strong>Introduction: </strong>The impact of Hormone Replacement Therapy (HRT) on cognitive function in postmenopausal women remains a topic of considerable debate. Although estrogen's neuroprotective effects suggest potential cognitive benefits, empirical findings are mixed.</p><p><strong>Methods: </strong>This study uses data from the Cognitive Function and Ageing Study Wales (CFAS Wales) cohort to explore the relationships between HRT use, age at menopause, APOE4 carrier status, lifestyle factors, comorbidities, and cognitive outcomes in older adult women. Two regression models were employed: one analyzing cognitive performance at follow-up and another examining changes in cognitive scores over time.</p><p><strong>Results: </strong>Results indicate that while age, education, HRT use, age at menopause, alcohol consumption, and diet were associated with cognitive function at a single later time point, only age remained a significant predictor when modeling cognition over time.</p><p><strong>Discussion: </strong>These findings suggest that while HRT, menopausal age and lifestyle factors may support cognitive stability, they do not necessarily predict cognitive decline in post-menopausal older women. A major limitation of the current work is the lack of detail regarding HRT use, such as formulation, timing and duration; caveats that future studies should address. The study underscores the need for longer follow-up periods, consideration of other female-specific risk factors, and more comprehensive lifestyle and health assessments to clarify the complex interplay between HRT use, reproductive history, lifestyle, comorbidities and cognitive aging in women.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1496051"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143083091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"A torch, a rope, a belly laugh": engaging with the multiple voices of support groups for people living with rare dementia. “一个火炬,一根绳子,一个捧腹大笑”:参与罕见痴呆症患者支持团体的多种声音。
Frontiers in dementia Pub Date : 2025-01-08 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1488025
Paul M Camic, Emma Harding, Sam Rossi-Harries, Oliver S Hayes, Mary Pat Sullivan, Lawrence Wilson, Nikki Zimmermann, Roberta McKee-Jackson, Joshua Stott, Nick C Fox, Catherine J Mummery, Jonathan D Rohrer, Jason D Warren, Rimona S Weil, Sebastian James Crutch
{"title":"\"A torch, a rope, a belly laugh\": engaging with the multiple voices of support groups for people living with rare dementia.","authors":"Paul M Camic, Emma Harding, Sam Rossi-Harries, Oliver S Hayes, Mary Pat Sullivan, Lawrence Wilson, Nikki Zimmermann, Roberta McKee-Jackson, Joshua Stott, Nick C Fox, Catherine J Mummery, Jonathan D Rohrer, Jason D Warren, Rimona S Weil, Sebastian James Crutch","doi":"10.3389/frdem.2024.1488025","DOIUrl":"10.3389/frdem.2024.1488025","url":null,"abstract":"<p><strong>Purpose: </strong>Rare forms of dementia bring unique difficulties related to age of onset, impact on family commitments, employment and finances, and also bring distinctive needs for support and care. The aim of the present study was to explore and better understand what the concept of support means for people living with different rare dementia (PLwRD) and their care-partners who attend ongoing support groups.</p><p><strong>Methods: </strong>Representing seven types of rare dementia, source material was collected from 177 PLwRD and care-partners attending in-person support groups, with the goal of developing research-informed group poems, co-constructed by a facilitating poet. Data were analyzed through a three-step process involving linguistic analysis followed by structured-tabular thematic analysis, relational analysis, and concluded with an online survey about participation in the study.</p><p><strong>Results: </strong>Linguistic analysis found that co-constructed poems remained faithful to the original source material offered by participants. These results provided confidence to subsequently conduct a thematic analysis of eight completed poems, identifying 15 initial themes. A further relational analysis between themes drew on six relational forms and identified an overarching theme \"A Community, Not an Intervention\" that describes the process of support for this population. Survey results revealed a varied but generally positive response to writing whilst reactions to the completed poems reflected strong emotional connections that resonated with personal experience.</p><p><strong>Conclusion: </strong>This is the first study that we are aware of to explore the use of co-constructed research poetry to better understand how in-person support groups provide support for people impacted by different rare dementias. The poems portray the complex, dynamic and relational aspects of how support groups provide a necessary form of connection for this population. An overarching theme characterized the support groups as a community rather than an intervention. Findings are discussed within the theoretical context of positive social identity, social health and biosocial groups. The results also demonstrate that solicited words from participants can be faithfully portrayed in poems co-created by an experienced poet. This novel finding expands methodological options for the use of research poetry in healthcare and also offers support group members further creative choices for engagement, connection and communication.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1488025"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region. 黎巴嫩老年人队列中的痴呆发病率:中东和北非地区的首次发病率估计。
Frontiers in dementia Pub Date : 2025-01-07 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1494719
Monique Chaaya, Sarah Assaad, Hala Darwish, Marc Haber, Rosemary Khoury, Dahlia Saab, Khalil El Asmar, Ramzi Hajjar
{"title":"Dementia incidence among a cohort of lebanese older adults: first incidence estimates from the Middle East and North Africa region.","authors":"Monique Chaaya, Sarah Assaad, Hala Darwish, Marc Haber, Rosemary Khoury, Dahlia Saab, Khalil El Asmar, Ramzi Hajjar","doi":"10.3389/frdem.2024.1494719","DOIUrl":"10.3389/frdem.2024.1494719","url":null,"abstract":"<p><strong>Objective: </strong>To provide the first estimates of dementia incidence rates among elderly in Lebanon.</p><p><strong>Methods: </strong>The cohort established in 2013 consisted of 470 elderly from Beirut and Mount Lebanon, who consented to be followed-up. In 2017, we reached 341 participants/informants, achieving a response rate of 72.6%. The validated Arabic version of the 10/66 Dementia Research Group diagnostic tool was administered through face-to-face interviews. Direct age standardization was applied to the data using the Western European population distribution. Age-, sex- and location-specific incidence rates were estimated.</p><p><strong>Results: </strong>After 3.5 years of follow up, 19 new cases of dementia were identified among 229 surviving participants. The crude incidence rate was 16.8 per 1,000 p-y, and the age standardized rate was 20.5 per 1,000 p-y. The incidence rate increased with age, going from 6.5 for those aged 65-74 years to 54.0 for those aged 85-89 years. Incidence rate was higher among females than males (20.7 vs.12.0), and higher in Mount Lebanon, as compared to the capital city Beirut (19.5 vs.14.9).</p><p><strong>Conclusion: </strong>Dementia incidence rate was close to European and North American countries' estimates. The use of validated tools increased the internal validity of our results. A large cohort study is warranted to confirm these results.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1494719"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the prevention approach in National Dementia Plans from European and North American countries. 考察欧洲和北美国家痴呆症国家计划的预防方法。
Frontiers in dementia Pub Date : 2025-01-03 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1463837
Mattia Andreoletti, Alessandro Blasimme
{"title":"Examining the prevention approach in National Dementia Plans from European and North American countries.","authors":"Mattia Andreoletti, Alessandro Blasimme","doi":"10.3389/frdem.2024.1463837","DOIUrl":"10.3389/frdem.2024.1463837","url":null,"abstract":"<p><strong>Objectives: </strong>This paper aims to provide a comprehensive review of National Dementia Plans (NDPs) from selected European and North American countries, focusing on the distinct prevention strategies outlined and the approaches employed for reducing dementia risk.</p><p><strong>Method: </strong>The sample consisted of 16 NDPs from Austria, Canada, Finland, France, Germany, Greece, Ireland, Italy, Liechtenstein, Luxembourg, Malta, the Netherlands, Spain, Switzerland, the UK, and the USA. These NDPs were retrieved from the Alzheimer's Disease International (ADI) database, with regular updates checked on official governmental websites. A qualitative analysis was conducted to identify common themes related to the vision, goals, and corresponding actions and measures within these strategies.</p><p><strong>Results: </strong>Our analysis revealed that dementia prevention is a strategic goal for most of the countries studied. Common actions identified include the identification of risk factors, advancing research, promoting healthy aging, increasing public awareness, and encouraging lifestyle interventions.</p><p><strong>Conclusion: </strong>We discuss the limitations and challenges of these actions, and more broadly, of the NDPs in relation to the recent literature on the most effective approaches to preventing dementia. We suggest adopting a more \"horizontal\" approach to dementia prevention, which current NDPs overlook in favor of \"vertical\" paradigms.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1463837"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11738615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Telehealth memory clinics in primary healthcare: real-world experiences from low-resource settings in Greece. 初级保健中的远程医疗记忆诊所:来自希腊低资源环境的真实经验。
Frontiers in dementia Pub Date : 2024-11-27 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1477242
Eleutheria Aggeletaki, Vasileios Stamos, Eleni Konidari, Apostolos Efkarpidis, Anna Petrou, Kalliopi Savvopoulou, Evangelia Kontogianni, Konstantinos Tsimpanis, Theofanis Vorvolakos, Antonios Politis, Panagiotis Alexopoulos
{"title":"Telehealth memory clinics in primary healthcare: real-world experiences from low-resource settings in Greece.","authors":"Eleutheria Aggeletaki, Vasileios Stamos, Eleni Konidari, Apostolos Efkarpidis, Anna Petrou, Kalliopi Savvopoulou, Evangelia Kontogianni, Konstantinos Tsimpanis, Theofanis Vorvolakos, Antonios Politis, Panagiotis Alexopoulos","doi":"10.3389/frdem.2024.1477242","DOIUrl":"10.3389/frdem.2024.1477242","url":null,"abstract":"<p><strong>Background: </strong>The role of primary healthcare is pivotal in the management of the surge of dementia prevalence particularly in low-resource areas. In this study, two telehealth-based memory clinics in primary healthcare operating within the frames of the INTegRated InterveNtion of pSychogerIatric Care (INTRINSIC) are presented.</p><p><strong>Methods: </strong>The first clinic, which is led by a general practitioner, operates at a primary healthcare center in a semi-mountainous area and closely collaborates with the geriatric psychiatry outpatient clinic of the Patras University General Hospital via a telehealth medicine platform. The second clinic is embedded at the General Hospital Center for Interconnected Psychiatric Support on the island of Syros, is led by registered nurses, and is interconnected with the geriatric psychiatry unit at the Eginition University Hospital in Athens.</p><p><strong>Results: </strong>Both memory clinics are in their infancy. At the general practitioner-led memory clinic, 13 beneficiaries were assessed and treated during the first 6 months of its operation. Cognitive decline and depressive and/or anxiety symptoms were detected in 10 and eight individuals, respectively. In 9 of the 27 beneficiaries of the registered nurse-led memory clinic, either mild cognitive impairment or dementia was diagnosed, while affective and/or anxiety symptoms were detected in almost all of them. Of note, only 14 beneficiaries of both clinics had received a diagnosis of a mental or neurocognitive disorder prior to their assessment at the memory clinics.</p><p><strong>Conclusion: </strong>Developing memory clinics in primary healthcare may be a pragmatic strategy to improve access of older adults living in low-resource areas to cognitive healthcare services.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1477242"},"PeriodicalIF":0.0,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of hypertension and its impact on cognitive functions in older adults: a cross-sectional study. 老年人高血压的特点及其对认知功能的影响:一项横断面研究。
Frontiers in dementia Pub Date : 2024-11-26 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1486147
Nivedita Parandiyal, Porimita Chutia, Shashank Saurabh Sinha, Pratyaksha Pandit, Naif Ali Majrashi, Naseem Qureshi, Shailendra Mohan Tripathi
{"title":"Characteristics of hypertension and its impact on cognitive functions in older adults: a cross-sectional study.","authors":"Nivedita Parandiyal, Porimita Chutia, Shashank Saurabh Sinha, Pratyaksha Pandit, Naif Ali Majrashi, Naseem Qureshi, Shailendra Mohan Tripathi","doi":"10.3389/frdem.2024.1486147","DOIUrl":"10.3389/frdem.2024.1486147","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a potentially modifiable risk factor for cognitive decline. Understanding the variables of hypertension related to cognitive functions will help in mitigating the risk.</p><p><strong>Objective: </strong>The study aims to assess the characteristics of hypertension and its effect on cognitive functions in the older adults.</p><p><strong>Methods: </strong>The study involved 95 hypertensive participants aged 60 years and above from cardiology and medicine outpatient services of a tertiary care hospital from August to October 2022. The characteristics of hypertension and cognitive functions were assessed using semi-structured proforma and Adenbrooke's Cognitive Examination (ACE-III) Hindi version respectively. Further, individual cognitive functions were compared with duration of the hypertension and hypertensive status of the participants. The chi-square test and independent <i>t</i>-tests were used and <i>p</i> value < 0.05 was considered to be significant.</p><p><strong>Result: </strong>The mean age of the study population was 68.2 years, the cognitive functions was comparable in terms of age, sex, locality, co-morbidity, and treatment characteristic. Although a significant difference in cognitive functions was present in relation to duration and status of hypertension. Among the individual cognitive domains, a significant difference was observed in attention and fluency domains of cognitive function based on HTN status (<i>p</i> > 0.05) but differential effect on cognitive domains was not seen with the duration of HTN. However, there was overall decline in cognitive domains with both hypertension status and the duration of hypertension.</p><p><strong>Conclusion: </strong>The study highlights association of status of hypertension and its characteristics with cognitive decline.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1486147"},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11628303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concerns about falling in people with Mild Cognitive Impairment and dementia: a scoping review of exercise interventions. 对轻度认知障碍和痴呆症患者跌倒的担忧:对运动干预的范围审查。
Frontiers in dementia Pub Date : 2024-11-20 eCollection Date: 2024-01-01 DOI: 10.3389/frdem.2024.1456125
Erica Dove, Patricia Hewston, Rosalie H Wang, Kara K Patterson, Arlene J Astell
{"title":"Concerns about falling in people with Mild Cognitive Impairment and dementia: a scoping review of exercise interventions.","authors":"Erica Dove, Patricia Hewston, Rosalie H Wang, Kara K Patterson, Arlene J Astell","doi":"10.3389/frdem.2024.1456125","DOIUrl":"10.3389/frdem.2024.1456125","url":null,"abstract":"<p><strong>Background: </strong>Concerns about falling (e.g., low balance confidence) increase fall risk in older populations with balance impairments. Exercise can improve physical limitations associated with falls (e.g., poor balance), which are more prevalent in people with Mild Cognitive Impairment (MCI) and dementia. This scoping review aimed to understand exercise interventions targeting concerns about falling in people with MCI and dementia.</p><p><strong>Methods: </strong>Using Arksey and O'Malley's five-stage scoping review framework, 968 search combinations were run across six electronic databases from inception to September 15, 2023. Articles were available in English full text, featured original peer-reviewed research with an intervention study design, targeted people with MCI or dementia with the exercise intervention, and included concerns about falling as an outcome measure.</p><p><strong>Results: </strong>Of the 2,111 articles screened, 27 met the inclusion criteria. Only one article looked at concerns about falling as a primary outcome; in the remaining studies, concerns about falling were a secondary outcome. Multi-modal interventions (i.e., containing more than one type of exercise) were most common, with balance and strength as the most frequently employed exercise types. Secondary results are presented on (i) intervention details, (ii) outcomes and measures for concerns about falling, (iii) participant accommodations, and (iv) components of effective interventions for concerns about falling.</p><p><strong>Conclusions: </strong>There is a lack of focus on concerns about falling experienced by people with MCI and dementia. Although concerns about falling were not the primary outcome of most papers, the results highlight the potential of exercise interventions to help address concerns about falling and other fall risk factors (e.g., balance, cognition) in people with MCI and dementia.</p>","PeriodicalId":520000,"journal":{"name":"Frontiers in dementia","volume":"3 ","pages":"1456125"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11615571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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