The National medical journal of India最新文献

{"title":"News from here and there.","authors":"","doi":"10.25259/NMJI_1606_2024","DOIUrl":"https://doi.org/10.25259/NMJI_1606_2024","url":null,"abstract":"","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"362-364"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SAPHO syndrome in a young male.","authors":"Karanjot Singh","doi":"10.25259/NMJI_1162_2023","DOIUrl":"https://doi.org/10.25259/NMJI_1162_2023","url":null,"abstract":"","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"356"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical linguistic proficiency programme: An approach to achieve multilingual proficiency.","authors":"Manik Inder Singh Sethi, Narayana Manjunatha","doi":"10.25259/NMJI_1146_2024","DOIUrl":"https://doi.org/10.25259/NMJI_1146_2024","url":null,"abstract":"","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"359-360"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opioid use disorder: Long-term use of oral naltrexone for promoting abstinence.","authors":"Vrinda Kabra, Muhammad Jadeer, Siddharth Sarkar","doi":"10.25259/NMJI_950_2024","DOIUrl":"https://doi.org/10.25259/NMJI_950_2024","url":null,"abstract":"","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"358-359"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid hormone resistance due to a novel mutation in thyroid hormone receptor presenting as attention deficit hyperactivity disorder.","authors":"Rini Yadav, Monika Goyal, Anshita Aggarwal, Bindu Kulshreshtha","doi":"10.25259/NMJI_869_2022","DOIUrl":"https://doi.org/10.25259/NMJI_869_2022","url":null,"abstract":"<p><p>Resistance to thyroid hormone (RTH) is rare and is characterized by high circulating levels of thyroid hormones in the presence of either normal or elevated thyroid stimulating hormone (TSH) levels. Decreased responsiveness of the peripheral tissues to thyroid hormones owing to defective thyroid receptor function is the underlying cause. RTH is variable in its presentation. We report a 21-year-old man with long-standing attention deficit hyperactivity disorder (ADHD) and learning disabilities. His thyroid function tests showed an increased free T3 and T4 in the presence of a non-suppressed TSH. Other pituitary hormones were normal. Subsequently, a genetic analysis revealed a heterozygous mutation (Pro452Thr) in THRβ gene, establishing the diagnosis of RTH. Thus, this was a RTH presenting as ADHD due to a novel mutation in the thyroid hormone receptor gene.</p>","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"332-334"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of perceptions, barriers and enablers towards uptake of research activities among undergraduate medical students: A mixed methods study.","authors":"Prateek Bobhate, Shivasakthy Manivasakan, Saurabh Rambiharilal Shrivastava","doi":"10.25259/NMJI_762_2022","DOIUrl":"https://doi.org/10.25259/NMJI_762_2022","url":null,"abstract":"<p><p>Background Medical research, even though, an integral part of medical education, remains the most neglected domain in the medical curriculum in most medical colleges across India. Research, when introduced in the medical curriculum, gives an early opportunity to medical students to participate in it. We did a study to gain an insight into the perceptions of medical students and explored barriers and enablers towards uptake of research activities. Methods A mixed methods study was done over 9 months using a pre-tested semi-structured questionnaire and a focus group discussion among medical students. First, a quantitative survey was done using Google forms to assess students perception and attitude towards research. This was followed by 2 focused group discussions to explore the barriers and enablers towards uptake of research activities. Descriptive analysis was done for quantitative data and manual thematic content analysis for qualitative data. Results A total of 350 participants responded to the survey out of which 168 (59.1%) were women. Most students (339; 96.9%) perceived research to be important. Also, 313 (89.4%) and 245 (70%) showed willingness to attend research methodology workshops and conduct research studies, respectively. A manual thematic content analysis of the focus group discussion revealed two main themes: (i) barriers to conduct of research and (ii) enablers towards uptake of research. The major barriers were lack of knowledge about conducting research and lack of time and financial constraints. The enablers were conduct of periodic research methodology workshops and adequate mentoring by faculty. Conclusion There is a gap in the existing knowledge and practice in undergraduate medical research. Our study ascertained potential barriers as well as enablers for enhancing research activities by medical students. Adequate institutional support including funding for research coupled with proper mentoring by faculty and family support is crucial to foster a positive research culture among undergraduate medical students.</p>","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"339-344"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lamellar cataract in a child with Alagille syndrome.","authors":"Sudarshan Khokhar, Deeksha Rani, Vaibhav Namdev, Aishwarya Rathod, Saumya Kumar","doi":"10.25259/NMJI_761_2022","DOIUrl":"https://doi.org/10.25259/NMJI_761_2022","url":null,"abstract":"<p><p>Alagille syndrome is a multisystem disorder inherited in an autosomal dominant manner with a variable phenotypic presentation. Typical features include intrahepatic bile duct paucity, butterfly-shaped vertebrae, typical facies, axenfeld anomaly (posterior embryotoxon) and cardiac abnormalities. Since this syndrome has typical ocular associations, ophthalmologists also have an important role in diagnosing the condition. Ocular features include posterior embryotoxon, corneal pannus, chorioretinal abnormalities and posterior subcapsular cataract. We report a toddler, diagnosed with Alagille syndrome who presented to us with a visually significant lamellar cataract in both eyes. To the best of our knowledge, this is the first case reporting lamellar cataract in a toddler with Alagille syndrome.</p>","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"327-328"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor functions and interventions to improve frailty in patients with heart failure.","authors":"Takuya Umehara, Akinori Kaneguchi, Nobuhisa Katayama, Wataru Kawakami, Daisuke Kuwahara, Nobuhiro Kito, Masayuki Kakehashi","doi":"10.25259/NMJI_743_2022","DOIUrl":"https://doi.org/10.25259/NMJI_743_2022","url":null,"abstract":"<p><p>Background There is limited research on the factors influencing frailty improvement and on whether exercise therapy is effective in the general population with heart failure. We aimed to examine the factors and interventions that affect the improvement of frailty in older patients with heart failure during hospitalization. Methods This multicentre prospective cohort study included patients with heart failure admitted and treated in the participating hospitals. Cox regression analysis was done to determine factors and interventions that affect improvement of frailty. After the Cox regression analysis, the receiver operating characteristic (ROC) curve was calculated for significant predictors to assess the cut-off point. Results The factors that affect improvement of frailty were the high short physical performance battery (SPPB) chair-stand test and hand grip strength values. The results of the ROC analysis revealed that the cut-off values of the SPPB chair-stand test and hand grip strength were 2 points and 13.7 kg, respectively. Interventions that affect frailty improvement were use of dobutamine, low resting heart rate, early days to start until aerobic exercise, and light intensity or higher of aerobic exercise. Moreover, the cut-off values of the resting heart rate, number of days to start until aerobic exercise, and intensity of aerobic exercise were 80 beats per minute, 7 days, and 31.6%, respectively. Conclusions Our results suggest that pharmacotherapy and exercise will be effective to improve frailty in patients with heart failure. In particular, early exercise therapy, including aerobic exercise, started within 7 days, may be effective to improve frailty in older patients with heart failure with low resting heart rate, depending on their condition on admission.</p>","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"304-310"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Genomics in Reshaping Healthcare Delivery: Personalized Medicine.","authors":"Chakradhara Rao S Uppugunduri, Adithan Chandrasekaran","doi":"10.25259/NMJI_93_2025","DOIUrl":"https://doi.org/10.25259/NMJI_93_2025","url":null,"abstract":"","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"301-303"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood safety training: Can virtual training replace in-person training?","authors":"Parmatma Prasad Tripathi, Vijay Kumawat","doi":"10.25259/NMJI_142_2024","DOIUrl":"https://doi.org/10.25259/NMJI_142_2024","url":null,"abstract":"<p><p>Background Healthcare professionals require continuous professional development and training to improve their knowledge and skills to prevent or minimize errors in blood transfusion. The novel Coronavirus-19 (Covid-19) pandemic affected face-to-face medical education and resulted in a shift from traditional education methods to online or virtual methods. We analysed the effect of virtual blood safety training on participant's knowledge and perception. Methods A prospective analysis of pre-test and post-test responses to a 25-item multiple choice questionnaire and feedback received for the training programme were analysed. The training feedback was obtained using a Google form link. Results The mean pre-test score of 131 analyzed participants was 16.02, which increased to 18.06 after the training. The difference was not statistically significant. The mean pre-test and post-test scores for doctors (n=45) were 17.91 and 19.33, respectively which was statistically significant. There was no statistically significant difference between the mean pre-test (15.03) and post-test (17.39) scores of technical staff (n=86). The majority (54%) preferred in-person physical training during feedback. Conclusion Virtual training can be conducted as a temporary measure. We did not find a difference in participants' knowledge except for doctors. The majority of participants preferred in-person training.</p>","PeriodicalId":519891,"journal":{"name":"The National medical journal of India","volume":"37 6","pages":"322-324"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}