Systems microbiology and biomanufacturing最新文献

Fermentation-mediated sustainable development and improvement of quality of plant-based foods: from waste to a new food 以发酵为媒介的可持续发展和植物性食品质量的改善：从废物到新食品

Systems microbiology and biomanufacturing Pub Date : 2024-07-09 DOI: 10.1007/s43393-024-00292-6

Elisabete Hiromi Hashimoto, Aline de Cassia Campos Pena, Mário Antônio Alves da Cunha, Ricardo de Freitas Branco, Kely Priscila de Lima, Gustavo Henrique Couto, Maria Giovana Binder Pagnoncelli

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Optimization of protease production using Bacillus velezensis through response surface methodology and investigating its applications as stain remover 通过响应面方法优化韦氏芽孢杆菌蛋白酶的生产，并研究其在去污剂中的应用

Systems microbiology and biomanufacturing Pub Date : 2024-07-02 DOI: 10.1007/s43393-024-00288-2

Humaira, Farah Deba, H. A. Shakir, M. Khan, Marcelo Franco, Muhammad Irfan

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Relationship between microbial protein and amino acid metabolism in fermented grains of long fermentation period strong-flavor Baijiu 长发酵期浓香型白酒发酵粮中微生物蛋白质与氨基酸代谢的关系

Systems microbiology and biomanufacturing Pub Date : 2024-07-01 DOI: 10.1007/s43393-024-00282-8

Xiaogang Liu, Lei Yuan, Dongna Ma, Shuangping Liu, Zhongwei Ji, Xiao Han, Caihong Shen, Jian Mao

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Enzymes in the bioconversion of food waste into valuable bioproducts: A circular economy perspective 将食物垃圾生物转化为有价值生物产品的酶：循环经济视角

Systems microbiology and biomanufacturing Pub Date : 2024-06-07 DOI: 10.1007/s43393-024-00283-7

Parushi Nargotra, Rhessa Grace Guanga Ortizo, Jia-Xiang Wang, Mei-Ling Tsai, Cheng-Di Dong, Pei-Pei Sun, B. Bajaj, Chia-Hung Kuo, Vishal Sharma

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Evaluation of brown midrib (bmr) sorghum stover as potential renewable biomass feedstock for poly(3-hydroxybutyrate) production employing Paraburkholderia Sacchari and Cupriavidus necator 评估利用 Paraburkholderia Sacchari 和 Cupriavidus necator 生产聚（3-羟基丁酸）时将棕色中肋高粱秸秆作为潜在可再生生物质原料的情况

Systems microbiology and biomanufacturing Pub Date : 2024-06-06 DOI: 10.1007/s43393-024-00281-9

Lisbeth Vallecilla Yepez, Mengxing Li, Scott E. Sattler, Mark R. Wilkins

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Preparation of rice fermented food using root of Asparagus racemosus as herbal starter and assessment of its nutrient profile. 用芦笋根作为草本启动剂制备大米发酵食品并评估其营养成分。

Systems microbiology and biomanufacturing Pub Date : 2022-01-01 Epub Date: 2021-08-04 DOI: 10.1007/s43393-021-00046-8

Papan Kumar Hor, Debabrata Goswami, Kuntal Ghosh, Miklós Takó, Suman Kumar Halder, Keshab Chandra Mondal

{"title":"Preparation of rice fermented food using root of Asparagus racemosus as herbal starter and assessment of its nutrient profile.","authors":"Papan Kumar Hor, Debabrata Goswami, Kuntal Ghosh, Miklós Takó, Suman Kumar Halder, Keshab Chandra Mondal","doi":"10.1007/s43393-021-00046-8","DOIUrl":"10.1007/s43393-021-00046-8","url":null,"abstract":"The popularity of traditional fermented food products is based on their healthiness. The addition of a starter brings consistent, desirable, and predictable food changes with improved nutritive, functional, and sensory qualities. The addition of a mixture of plant residues as a starter or source of microbes is an age-old practice to prepare traditional fermented food and beverages, and most of the reported data on traditional foods were based on the analysis of the final product. The contribution of an individual starter component (plant residue) is not experimentally substantiated for any traditional fermented food, but this data are very essential for the formulation of an effective starter. In this study, Asparagus racemosus, which used as a common ingredient of starter for preparation of rice fermented food in the Indian sub-continent, was used as a starter for the preparation of rice fermented food under laboratory scale, and its microbial and nutrient profile was evaluated. The fermented product was a good source of lactic acid bacteria, Bifidobacterium sp., yeast, etc. The food product was acidic and enriched with lactic acid and acetic acid with titratable acidity of 0.65%. The content of protein, fat, minerals, and vitamins (water-soluble) was considerably improved. Most notably, oligosaccharide (G3-matotriose), unsaturated fatty acids (ω3, ω6, ω7, and ω9), and a pool of essential and non-essential amino acids were enriched in the newly formulated food. Thus, the herbal starter-based rice fermented food would provide important macro- and micronutrients. They could also deliver large numbers of active microorganisms for the sustainability of health. Therefore, the selected plant part conferred its suitability as an effective starter for the preparation of healthier rice-based food products.Graphic abstract: ","PeriodicalId":519888,"journal":{"name":"Systems microbiology and biomanufacturing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioreactor control systems in the biopharmaceutical industry: a critical perspective. 生物制药工业中的生物反应器控制系统：一个重要的视角。

Systems microbiology and biomanufacturing Pub Date : 2022-01-01 Epub Date: 2021-08-05 DOI: 10.1007/s43393-021-00048-6

Sagnik Mitra, Ganti S Murthy

{"title":"Bioreactor control systems in the biopharmaceutical industry: a critical perspective.","authors":"Sagnik Mitra, Ganti S Murthy","doi":"10.1007/s43393-021-00048-6","DOIUrl":"https://doi.org/10.1007/s43393-021-00048-6","url":null,"abstract":"Industrial-scale bioprocessing underpins much of the production of pharmaceuticals, nutraceuticals, food, and beverage processing industries of the modern world. The profitability of these processes increasingly leverages the economies of scale and scope that are critically dependent on the product yields, titers, and productivity. Most of the processes are controlled using classical control approaches and represent over 90% of the industrial controls used in bioprocessing industries. However, with the advances in the production processes, especially in the biopharmaceutical and nutraceutical industries, monitoring and control of bioprocesses such as fermentations with GMO organisms, and downstream processing has become increasingly complex and the inadequacies of the classical and some of the modern control systems techniques is becoming apparent. Therefore, with increasing research complexity, nonlinearity, and digitization in process, there has been a critical need for advanced process control that is more effective, and easier process intensification and product yield (both by quality and quantity) can be achieved. In this review, industrial aspects of a process and automation along with various commercial control strategies have been extensively discussed to give an insight into the future prospects of industrial development and possible new strategies for process control and automation with a special focus on the biopharmaceutical industry.Supplementary information: The online version contains supplementary material available at 10.1007/s43393-021-00048-6.","PeriodicalId":519888,"journal":{"name":"Systems microbiology and biomanufacturing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tailoring in fungi for next generation cellulase production with special reference to CRISPR/CAS system. 为下一代纤维素酶生产定制真菌，特别是 CRISPR/CAS 系统。

Systems microbiology and biomanufacturing Pub Date : 2022-01-01 Epub Date: 2021-07-29 DOI: 10.1007/s43393-021-00045-9

Subhadeep Mondal, Suman Kumar Halder, Keshab Chandra Mondal

{"title":"Tailoring in fungi for next generation cellulase production with special reference to CRISPR/CAS system.","authors":"Subhadeep Mondal, Suman Kumar Halder, Keshab Chandra Mondal","doi":"10.1007/s43393-021-00045-9","DOIUrl":"https://doi.org/10.1007/s43393-021-00045-9","url":null,"abstract":"Cellulose is the utmost plenteous source of biopolymer in our earth, and fungi are the most efficient and ubiquitous organism in degrading the cellulosic biomass by synthesizing cellulases. Tailoring through genetic manipulation has played a substantial role in constructing novel fungal strains towards improved cellulase production of desired traits. However, the traditional methods of genetic manipulation of fungi are time-consuming and tedious. With the availability of the full-genome sequences of several industrially relevant filamentous fungi, CRISPR-CAS (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein) technology has come into the focus for the proficient development of manipulated strains of filamentous fungi. This review summarizes the mode of action of cellulases, transcription level regulation for cellulase expression, various traditional strategies of genetic manipulation with CRISPR-CAS technology to develop modified fungal strains for a preferred level of cellulase production, and the futuristic trend in this arena of research.","PeriodicalId":519888,"journal":{"name":"Systems microbiology and biomanufacturing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glycerol waste to value added products and its potential applications. 甘油废物转化为增值产品及其潜在应用。

Systems microbiology and biomanufacturing Pub Date : 2021-01-01 Epub Date: 2021-06-07 DOI: 10.1007/s43393-021-00036-w

Chaitanya Reddy Chilakamarry, A M Mimi Sakinah, A W Zularisam, Ashok Pandey

{"title":"Glycerol waste to value added products and its potential applications.","authors":"Chaitanya Reddy Chilakamarry, A M Mimi Sakinah, A W Zularisam, Ashok Pandey","doi":"10.1007/s43393-021-00036-w","DOIUrl":"https://doi.org/10.1007/s43393-021-00036-w","url":null,"abstract":"The rapid industrial and economic development runs on fossil fuel and other energy sources. Limited oil reserves, environmental issues, and high transportation costs lead towards carbon unbiased renewable and sustainable fuel. Compared to other carbon-based fuels, biodiesel is attracted worldwide as a biofuel for the reduction of global dependence on fossil fuels and the greenhouse effect. During biodiesel production, approximately 10% of glycerol is formed in the transesterification process in a biodiesel plant. The ditching of crude glycerol is important as it contains salt, free fatty acids, and methanol that cause contamination of soil and creates environmental challenges for researchers. However, the excessive cost of crude glycerol refining and market capacity encourage the biodiesel industries for developing a new idea for utilising and produced extra sources of income and treat biodiesel waste. This review focuses on the significance of crude glycerol in the value-added utilisation and conversion to bioethanol by a fermentation process and describes the opportunities of glycerol in various applications.Graphic abstract: ","PeriodicalId":519888,"journal":{"name":"Systems microbiology and biomanufacturing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0