Revista de Gastroenterologia de Mexico最新文献

{"title":"Comentarios sobre Características clínicas y tratamiento de la esofagitis eosinofílica en población adulta en Colombia","authors":"D. García-Compeán, A.R. Jiménez-Rodríguez","doi":"10.1016/j.rgmx.2025.08.004","DOIUrl":"10.1016/j.rgmx.2025.08.004","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 148-149"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Desarrollo de un modelo de aprendizaje automático para predecir recurrencia en el cáncer de colon derecho: estudio piloto retrospectivo unicéntrico","authors":"R. Zayas-Bórquez,&nbsp;J. Canto-Losa,&nbsp;E. Posadas-Trujillo,&nbsp;N. Salgado-Nesme,&nbsp;O. Santes","doi":"10.1016/j.rgmx.2025.07.011","DOIUrl":"10.1016/j.rgmx.2025.07.011","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Right-sided colon cancer (RSCC) is characterized by distinct clinical features and recurrence patterns. Our study aimed to develop a predictive model for distant recurrence in patients with RSCC who underwent curative surgery, employing the random forest machine learning algorithm, based on clinical and histopathologic variables.</div></div><div><h3>Materials and methods</h3><div>A retrospective analysis of 64 patients treated within the time frame of 2016-2024 was conducted. The variables included age, sex, lymphovascular invasion, and number of lymph nodes evaluated (transformed for inverse interpretation). Oversampling was employed to balance the dataset and a random forest model for predicting distant recurrence (defined as that occurring at least six months after surgery) was constructed. Its performance was evaluated through accuracy, sensitivity, F1 score, and area under the ROC curve (AUC).</div></div><div><h3>Results</h3><div>The model achieved an AUC of 0.76 in the test set and a mean AUC of 0.81 in cross-validation, with 75% sensitivity and 100% specificity. The most relevant variables were low lymph node harvest, older age, male sex, and lymphovascular invasion. A simplified model with those four variables maintained 95% accuracy. A clinical risk scale based on cumulative scores was developed that classified patients into low-risk and high-risk groups, with distant recurrence rates of 8.3% and 56.3%, respectively.</div></div><div><h3>Conclusion</h3><div>The predictive model showed a robust capacity for stratifying the distant recurrence risk, supporting the use of machine learning algorithms as a complementary tool in the individualized management of RSCC.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 68-75"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cáncer de esófago postendoscopia: lecciones de una cohorte multicéntrica en Colombia","authors":"R. Castaño-Llano ,&nbsp;L.J. Palacios ,&nbsp;J.R. Jaramillo ,&nbsp;M. Rodríguez ,&nbsp;N. Cortés ,&nbsp;J.M. Castro ,&nbsp;C. Díaz ,&nbsp;D. Restrepo ,&nbsp;J.E. Puerta ,&nbsp;I. Mejía ,&nbsp;D. Palacio ,&nbsp;O. Álvarez","doi":"10.1016/j.rgmx.2025.07.014","DOIUrl":"10.1016/j.rgmx.2025.07.014","url":null,"abstract":"<div><h3>Introduction</h3><div>The incidence of esophageal adenocarcinoma (EAC) has increased. Although there are screening and surveillance programs, especially for patients with Barrett's esophagus (BE), they have limited effectiveness in detecting early disease. Post-endoscopy esophageal adenocarcinoma (PEEC), diagnosed after previous negative endoscopies, raises concerns about the accuracy of current endoscopic practices in high-risk patients.</div></div><div><h3>Aims</h3><div>Primary aim: to estimate the rate of PEEC and analyze its characteristics in patients at 3<!--> <!-->hospital centers in Medellín, Colombia.</div></div><div><h3>Specific aims</h3><div><ul><li><span>•</span><span><div>To compare characteristics between patients with PEEC and those diagnosed at the first endoscopy.</div></span></li><li><span>•</span><span><div>Evaluate the prevalence of BE in the 2<!--> <!-->cohorts and its relation to PEEC.</div></span></li><li><span>•</span><span><div>Analyze the anatomic location of PEEC.</div></span></li></ul></div></div><div><h3>Materials and methods</h3><div>An observational cohort study was conducted that included 473 patients diagnosed with esophageal cancer between 2012 and 2023 at 3<!--> <!-->centers in Medellín, Colombia, 31 of whom had PEEC. Their demographic, clinical, and survival data were evaluated using the STROBE guidelines for cohort studies (pages 22-26).</div></div><div><h3>Results</h3><div>The PEEC rate was 6.6%. Patients with PEEC presented with fewer alarm symptoms (35% vs. 63%, <em>P</em>=.002), a higher prevalence of BE (42% vs. 23%, <em>P</em>=.016), and were diagnosed at an earlier stage of disease. The previous endoscopies failed to detect lesions, especially in the proximal esophagus.</div></div><div><h3>Conclusions</h3><div>PEEC is a frequent entity, especially in patients with BE and proximal lesions. Optimizing endoscopy through advanced imaging techniques and strict surveillance protocols is required.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 57-67"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"El futuro de la elastografía esplénica: ¿es una herramienta útil para el tratamiento personalizado?","authors":"D.K. Tapia Calderón ,&nbsp;E. Llop Herrera ,&nbsp;J.L. Calleja Panero ,&nbsp;E.S. García Jiménez ,&nbsp;G. Castro Narro ,&nbsp;J.A. Velarde-Ruiz Velasco","doi":"10.1016/j.rgmx.2025.12.004","DOIUrl":"10.1016/j.rgmx.2025.12.004","url":null,"abstract":"<div><div>Portal hypertension is the main determinant of prognosis in liver cirrhosis. The gold standard for its evaluation is hepatic venous pressure gradient measurement. Because it is an invasive test performed only at highly specialized centers, noninvasive tools for the detection of portal hypertension have been developed. One of the most relevant is vibration-controlled transient elastography (FibroScan®; Echosens, Paris, France). Liver stiffness measurement is the most widely utilized and validated noninvasive tool, although more recent studies suggest spleen stiffness measurement correlates better with the hepatic venous pressure gradient. In the present narrative review, a comprehensive search of the literature was carried out on the PubMed/Medline, Embase, and Cochrane CENTRAL databases, complemented by manual reference screening, to critically analyze the available evidence on splenic elastography in the noninvasive evaluation of portal hypertension. The following topics are addressed: the clinical impact of portal hypertension evaluation, the role of liver elastography as a noninvasive strategy, and the different applications of splenic elastography in the evaluation of portal pressure, including the diagnosis of clinically significant portal hypertension and severe portal hypertension, the prediction of esophageal varices and high-risk varices, clinical decompensation and recompensation risk assessment, and the usefulness of spleen stiffness measurement in monitoring the response to beta blocker therapy.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 76-88"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proteína C reactiva y diagnóstico temprano de fuga anastomótica en cirugía colorrectal: ¿un estándar en evolución?","authors":"R. Zayas-Bórquez,&nbsp;J. Canto-Losa,&nbsp;E. Posadas-Trujillo,&nbsp;N. Salgado-Nesme,&nbsp;O. Santes","doi":"10.1016/j.rgmx.2025.06.006","DOIUrl":"10.1016/j.rgmx.2025.06.006","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Anastomotic leakage is a critical complication in colorectal surgery, significantly associated with postoperative morbidity and mortality. Early detection of at-risk patients is essential for optimizing clinical outcomes. The present study investigates the utility of C-reactive protein (CRP) as a predictive inflammatory biomarker for anastomotic leakage.</div></div><div><h3>Materials and methods</h3><div>A retrospective observational study was conducted at the <em>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán</em>, analyzing 95 patients who underwent colorectal surgery within the time frame of March 2023 and July 2024. CRP levels were measured on postoperative days 1, 3, and 5. The predictive capacity was measured through ROC curves, determining the optimum cutoff points with the Youden index.</div></div><div><h3>Results</h3><div>CRP on day 3 showed an AUC of 0.91, with an optimum cutoff point of 186.9<!--> <!-->mg/dL (Youden index<!--> <!-->=<!--> <!-->0.73). On day 5, the AUC was 0.93, with a cutoff point of 142.5<!--> <!-->mg/dL (Youden index<!--> <!-->=<!--> <!-->0.73). Both measurements showed high sensitivity and specificity for predicting anastomotic leakage.</div></div><div><h3>Conclusion</h3><div>Elevated CRP levels on postoperative days 3 and 5 emerged as robust predictors of anastomotic leakage, potentially guiding early interventions and improving patient prognosis.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 29-33"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrosis esofágica aguda: una condición rara pero potencialmente mortal. Experiencia de una serie de casos","authors":"M. Londoño-Barrientos ,&nbsp;C.A. Delgado-López ,&nbsp;M. Castrillón-Bustamante ,&nbsp;J.E. Troncoso-Correa ,&nbsp;I. Jiménez-Cadavid ,&nbsp;G. Mosquera-Klinger","doi":"10.1016/j.rgmx.2025.10.004","DOIUrl":"10.1016/j.rgmx.2025.10.004","url":null,"abstract":"<div><div>Acute esophageal necrosis (AEN) is a rare and severe entity characterized by diffuse necrosis of the mucosa, mainly in the distal esophagus, with a mortality rate close to 40%. We present herein six cases diagnosed through upper gastrointestinal endoscopy. The mean patient age was 62<!--> <!-->years (range 33-86) and females were predominant (5/6). The most frequent comorbidities were diabetes mellitus and high blood pressure (5/6, each entity). The main symptoms included melena, hematemesis, and epigastric pain. Two patients presented with diabetic ketoacidosis and sepsis. Endoscopy revealed diffuse necrosis in all the cases and perforation in two cases. Two patients were discharged from the hospital, one received palliative care, and two died due to multiple organ failure (40% mortality). Management included proton pump inhibitors, antibiotics, antifungals, and nutritional support. AEN requires early diagnosis and a multidisciplinary approach to prevent major complications, such as bleeding and perforation.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 144-147"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quiste perianal gigante. Una localización atípica de un quiste epidermoide","authors":"E. Calcerrada-Alises,&nbsp;C. Gilsanz-Martín,&nbsp;A. Vaquero-Rodríguez,&nbsp;A. Alonso-Poza","doi":"10.1016/j.rgmx.2025.04.010","DOIUrl":"10.1016/j.rgmx.2025.04.010","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 115-117"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147557044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor sólido pseudopapilar del páncreas: hallazgos clínicos, histopatológicos y moleculares en una cohorte de pacientes mexicanos","authors":"Y. Svyryd ,&nbsp;L.F. Uscanga-Domínguez ,&nbsp;A. Ángeles-Ángeles ,&nbsp;O.E. Falcón-Antonio ,&nbsp;I. Domínguez-Rosado ,&nbsp;C. Chan-Núñez ,&nbsp;E.E. Huerta-Ávila ,&nbsp;P. Rodríguez-García ,&nbsp;E. Rodarte-López ,&nbsp;O.M. Mutchinick","doi":"10.1016/j.rgmx.2025.06.014","DOIUrl":"10.1016/j.rgmx.2025.06.014","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Solid pseudopapillary tumor of the pancreas (SPTP) is a rare pancreatic neoplasm of low malignant potential. It predominantly affects young women and raises ongoing questions about its origin and behavior. We aimed to evaluate somatic mutations of the β-catenin (<em>CTNNB1)</em> gene in Mexican patients with SPTP and assess clinical and molecular genotype-phenotype correlations in this rare tumor.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study of SPTP patients (1997-2023) was conducted at a tertiary care medical center. Tumor and non-affected pancreatic tissue samples underwent staining, immunohistochemistry testing, DNA extraction, and <em>CTNNB1</em> gene exon-3 sequencing.</div></div><div><h3>Results</h3><div>Of the 37 cases of SPTP studied, 36 were female, and one was male. Most tumors of variable sizes occurred in the pancreatic head or tail (78.4%). Immunohistochemical studies always revealed β-catenin expression and pathological analysis confirmed lymph node invasion. <em>CTNNB1</em> gene sequencing showed mutations in 34 of 37 tumors (91.9%), exclusively affecting codons 32, 33, 34, and 37.</div></div><div><h3>Conclusions</h3><div>The results show clinical and immunohistochemical associations with pancreatic tumor location, tissue invasion, and specific gene mutations. These findings highlight the prevalence of <em>CTNNB1</em> mutations in SPTP and underscore the significance of examining population diversity in rare tumor research to determine the likelihood of clinical and molecular correlations for personalized treatment.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 34-43"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147557037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enfermedad celíaca de presentación no clásica con serología de escrutinio negativa. Reporte de caso","authors":"D.A. Calle-Rodas ,&nbsp;P.D. Muñoz-Espinoza ,&nbsp;M.A. Corral-Cazorla","doi":"10.1016/j.rgmx.2025.06.007","DOIUrl":"10.1016/j.rgmx.2025.06.007","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 125-128"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147557040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resultados funcionales posterior a rectopexia ventral con malla en 50 pacientes con obstrucción defecatoria y/o incontinencia fecal","authors":"A. Rivera GarcíaGranados,&nbsp;M.A. López-Ramírez,&nbsp;F. Urbina-Alatriste,&nbsp;V. Flores-Gamboa","doi":"10.1016/j.rgmx.2025.05.002","DOIUrl":"10.1016/j.rgmx.2025.05.002","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Ventral mesh rectopexy (VMR) for correcting rectal prolapse, rectocele, and enterocele improves obstructed defecation syndrome (ODS) and fecal incontinence (FI). This procedure is popular due to its minimally invasive approach and favorable clinical outcomes. Our aim was to evaluate the clinical response of patients that underwent VMR, focusing on changes in the ODS and FI scores.</div></div><div><h3>Material and methods</h3><div>A retrospective, observational, cohort study was conducted on patients that underwent VMR within the time frame of May 2019 and May 2024 at a high-volume hospital. Fifty case records were analyzed, measuring the changes in the scores of the ODS scale and CCF-FIS, before and after surgery. Statistical significance was set at a p &lt;<!--> <!-->0.05.</div></div><div><h3>Results</h3><div>The ODS scores decreased from 10.76 to 6.28 and the FI scores from 9 to 5, showing significant improvement. When analyzing individual items of each of the scales separately, all in the ODS scale were statistically significant, whereas in the FI scale, only pad use and impact on social life were significant. There were no major intraoperative complications or conversions to open surgery and the mean hospital stay was1.96 days. No significant differences in outcomes were found between the conventional and robotic laparoscopic approaches.</div></div><div><h3>Conclusions</h3><div>VMR is a safe and effective procedure for improving ODS and FI symptoms in the Mexican population. Long-term follow-up is required to confirm the persistence of benefits and evaluate late complications.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 1","pages":"Pages 12-18"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147556547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}