Case Reports in Cardiology最新文献

{"title":"Use of OCT Imaging in the Treatment of Right Coronary Artery Occlusion Causing NSTEMI as an Initial Complication of Essential Thrombocythaemia.","authors":"Robert Michael, Jith Somaratne, Nicola Eaddy","doi":"10.1155/cric/6647538","DOIUrl":"10.1155/cric/6647538","url":null,"abstract":"<p><strong>Background: </strong>Essential thrombocythaemia (ET) is a chronic myeloproliferative neoplasm characterised by clonal thrombocytosis and an overall increased risk of thrombotic events. Acute coronary syndrome as an initial presentation of ET is rare in the literature.</p><p><strong>Case summary: </strong>A 39 year old woman with established ET presented with non-ST-elevation myocardial infarction (NSTEMI). Coronary angiography revealed a hazy, eccentric mid-right coronary artery lesion. Optical coherence tomography (OCT) demonstrated thrombus without atherosclerotic plaque. OCT-guided direct stenting achieved optimal expansion with thrombolysis in myocardial infarction (TIMI) Grade III flow. She was discharged on dual antiplatelet therapy and referred to haematology for ET management. At three months, she remained asymptomatic on clinic follow-up.</p><p><strong>Conclusion: </strong>OCT provided diagnostic and procedural guidance in a rare thrombotic NSTEMI secondary to ET. This case highlights the role of intracoronary imaging in differentiating thrombosis from atherosclerotic plaque rupture.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"6647538"},"PeriodicalIF":0.5,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12933134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147312456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Kingella kingae</i> Endocarditis and Septic Pulmonary Emboli in a 12-Year-Old Male With Repaired Tetralogy of Fallot and a Bioprosthetic Pulmonary Valve.","authors":"Cyndee Jocson, Steffan Sernich, Patrick Nelson, Timothy Pettitt","doi":"10.1155/cric/2583276","DOIUrl":"10.1155/cric/2583276","url":null,"abstract":"<p><p><i>Kingella kingae</i>, typically known for causing osteoarticular infections in young children, is an emerging cause of infective endocarditis (IE) in older children with congenital heart disease. This report describes a 12-year-old with repaired tetralogy of Fallot and a bioprosthetic pulmonary valve who developed culture-negative IE due to <i>K. kingae</i>, confirmed by microbial cell-free DNA testing and valve tissue PCR. His course was complicated by septic pulmonary emboli, requiring valve replacement. The case highlights the role of molecular diagnostics in managing culture-negative IE and the need for timely surgical intervention in the presence of embolic complications.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"2583276"},"PeriodicalIF":0.5,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent Hiccups as an Atypical Sole Manifestation of ST-Segment Elevation Myocardial Infarction: An Interesting Case Report.","authors":"Osman Farah Dahir, Said Abdirahman Ahmed, Ahmed Elmi Abdi, Ahmed Shafie Aden, Ishak Ahmed Abdi, Mohamud Mire Waberi, Mohamed Omar Hassan, Mohamed Abdullahi Mohamud, Abdullahi Mohamed Hassan Fujeyra, Mohammed A M Ahmed, Salad Mahamud Mahamed, Mohamed Sheikh Hassan, Feyza Aksu, Abdijalil Abdullahi Ali","doi":"10.1155/cric/1123999","DOIUrl":"10.1155/cric/1123999","url":null,"abstract":"<p><strong>Background: </strong>Myocardial infarction (MI) commonly presents with chest pain, dyspnea, diaphoresis, and nausea; however, atypical and nonclassical presentations are increasingly recognized and may delay diagnosis and management. Persistent hiccups as the sole presenting manifestation of ST-elevation myocardial infarction (STEMI) are exceedingly rare, with only a few cases reported. Awareness of such unusual presentations is essential to avoid missed or delayed diagnoses.</p><p><strong>Case presentation: </strong>A 60-year-old male presented to the outpatient clinic with a 1-month history of persistent hiccups without chest pain or other associated symptoms. He had no significant past medical history, cardiovascular risk factors, or prior medication use. Physical examination and vital signs were within normal limits. Laboratory evaluation revealed markedly elevated cardiac troponin levels (20 ng/mL), whereas creatine kinase, AST, lactate dehydrogenase, and B-type natriuretic peptide levels were within normal ranges. Electrocardiography showed normal sinus rhythm with ST-segment elevation and deep <i>Q</i> waves in the inferior leads, more prominent in Lead III than Lead II, suggestive of right coronary artery (RCA) involvement. Transthoracic echocardiography demonstrated preserved left ventricular systolic function (ejection fraction 64%) with inferior wall hypokinesia. Urgent coronary angiography revealed total occlusion of the distal RCA, with no significant disease in the left anterior descending or circumflex arteries. The patient underwent successful percutaneous coronary intervention with balloon angioplasty and drug-eluting stent implantation, resulting in restoration of coronary blood flow. His hospital course was uneventful, and he was discharged on dual antiplatelet therapy planned for 12 months.</p><p><strong>Discussion: </strong>The proposed mechanism of hiccups in inferior wall MI involves irritation of the phrenic or vagus nerves due to ischemia or inflammation near the diaphragm, particularly in RCA territory infarctions. Review of previously reported cases demonstrates a consistent association between persistent hiccups and inferior wall ischemia, most often related to RCA occlusion. This case reinforces the need to consider cardiac etiologies in patients with unexplained or refractory hiccups, even in the absence of classical ischemic symptoms.</p><p><strong>Conclusion: </strong>Persistent hiccups may represent a rare but important atypical presentation of inferior wall STEMI. Early cardiac evaluation, including electrocardiography and cardiac biomarkers, should be considered in such cases to enable timely diagnosis and intervention, potentially improving patient outcomes.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"1123999"},"PeriodicalIF":0.5,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12927889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the Healthcare System Breaks a Heart: A Case of Stress Cardiomyopathy Following a Conversation With an Insurance Provider.","authors":"Kramer J Wahlberg, Friederike K Keating, Salmaan Mumtaz, Krina Patel, Ahmed A Harhash","doi":"10.1155/cric/9942574","DOIUrl":"10.1155/cric/9942574","url":null,"abstract":"<p><p>Stress related to healthcare has been associated with adverse outcomes for patients with chronic conditions, including cardiovascular disease. We describe the case of an otherwise healthy patient who developed stress cardiomyopathy triggered by an emotional conversation with their healthcare insurance provider. A conversation regarding coverage that included preventative care for an asymptomatic patient resulted in the development of a cardiovascular emergency, transfer to a tertiary care cardiology service, antithrombotic therapy, and invasive procedures, all of which carried inherent risk and significant cost. The case illustrates the presentation, workup, management, and natural history of typical stress cardiomyopathy while providing the opportunity to highlight the brain-heart axis and consequences of healthcare-related stress.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"9942574"},"PeriodicalIF":0.5,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12920255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysrhythmia due to Verapamil Overdose in a Young Woman.","authors":"Abdollah Malakian, Ensiyeh Taghizadeh, Zakaria Zakariaei","doi":"10.1155/cric/8747772","DOIUrl":"10.1155/cric/8747772","url":null,"abstract":"<p><p>Verapamil (VER) is characterized as a calcium channel blocker (CCB) that can be intentionally or unintentionally overdosed. This drug, like other CCBs, inhibits the entry of calcium into vascular and myocardial tissues through L-type channels. VER exerts negative inotropic and chronotropic effects on the myocardium through antagonistic L-type calcium channels, and an overdose of this drug can result in a decrease in cardiac output, hypotension, and shock. In this report, we describe a unique case of VER toxicity in a 30-year-old woman who experienced a dysrhythmia and heart block after intentionally ingesting 800 mg of sustained-release VER tablets.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"8747772"},"PeriodicalIF":0.5,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12920256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longevity and Innovation: Cardiac Resynchronization Therapy in a 100-Year-Old Patient With Severe Heart Failure-A 4-Year Follow-Up.","authors":"Ayman Helal, Ibrahim Antoun, Rachana Prasad","doi":"10.1155/cric/7961581","DOIUrl":"10.1155/cric/7961581","url":null,"abstract":"<p><p>Cardiac resynchronization therapy (CRT) has been shown to improve outcomes in patients with severe left ventricular systolic dysfunction (LVSD) and electrical dyssynchrony. This case report presents a 100-year-old male with a history of atrial fibrillation (AF), left bundle branch block (LBBB), and ischemic heart disease, who was admitted with chest pain and episodes of bradycardia. After careful consideration, CRT-P was successfully implanted. The patient's condition was closely monitored postimplantation, and a 4-year follow-up revealed significant symptomatic improvement and functional independence. This report highlights the importance of CRT-P in improving quality of life and managing heart failure in very elderly patients.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"7961581"},"PeriodicalIF":0.5,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ST-Elevation Myocardial Infarction Secondary to Intracoronary Air Embolism During Atrial Fibrillation Ablation: Case Report and Successful Management.","authors":"Eduardo I Arteaga-Chan, Luis R Cano-Del Val Meraz, Rafael A Sandoval-Espadas, Carlos A Castro-Garcia, Andres Aguilar-Silva, Fernando Huerta-Liceaga","doi":"10.1155/cric/4448297","DOIUrl":"10.1155/cric/4448297","url":null,"abstract":"<p><p>We present the case of a 47-year-old woman with persistent atrial fibrillation who underwent catheter ablation. During the procedure, real-time ST-segment elevation was observed on surface ECG. An emergency coronary angiography revealed an air embolism in the proximal segment of the left anterior descending (LAD) coronary artery. Intracoronary adenosine was administered, successfully restoring coronary flow (TIMI 3). The procedure was aborted, and the patient was subsequently managed in the coronary care unit due to biventricular cardiogenic shock secondary to myocardial stunning. This case highlights the importance of strict hemodynamic monitoring and prompt recognition and response to uncommon complications during catheter ablation procedures.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"4448297"},"PeriodicalIF":0.5,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hope in Miniature: The First Case of Implantation of a \"Tiny Pacemaker\" in Italy as a Successful Treatment for Congenital Atrioventricular Block in a Low Birth Weight Child.","authors":"Ferrari Paola, Limonta Raul, Malanchini Giovanni, Patanè Luisa, De Filippo Paolo","doi":"10.1155/cric/3682992","DOIUrl":"10.1155/cric/3682992","url":null,"abstract":"<p><p>Congenital complete atrioventricular block (CAVB) is a rare cardiac condition occurring in approximately one in 15,000 to one in 22,000 live births. Maternal autoimmune diseases, with anti-ssA (Ro) and anti-ssB (La) antibodies implicated in 56%-90% of cases, are primary causes. We present a case of a 31-year-old primigravid woman referred at 29 weeks of gestation for fetal high-grade AVB, initially diagnosed as 2:1 AVB with a ventricular rate of 45 bpm. Maternal corticosteroid therapy was initiated for suspected immune-mediated etiology, pending autoantibody test results. Upon transfer, a 3:1 AVB was detected, with fetal heart failure signs. Genetic and autoimmune evaluations ruled out primary electrical heart diseases and infections. Prompt intervention was necessitated due to fetal cardiac decompensation. Sympathomimetic drugs via placental circulation were ineffective. Cesarean section was scheduled at 30 weeks and 1 day. The neonate, weighing 1280 g, had an APGAR score of 7 and a heart rate of 40 bpm. Initial resuscitation and isoproterenol infusion resulted in a moderate heart rate increase. Temporary pacing wires were surgically placed. As permanent pacemaker implantation became necessary, traditional venous access was impractical. A \"tiny pacemaker\" made with modification of a Medtronic Micra MC1VR01 generator connected to an epicardial lead ensured hemodynamic stability. Approval of this off-label device from the Italian Ministry of Health was swiftly obtained. Diagnosis of CAVB typically involves fetal echocardiography and fetal magnetocardiography for precise arrhythmia diagnosis. Treatment varies, with fluorinated steroids reducing block severity in autoimmune cases. Miniaturized pacemakers offer a promising solution for neonates, addressing challenges of conventional devices. Further research is needed to evaluate their long-term efficacy and safety, potentially benefiting patients with venous and cardiac abnormalities.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"3682992"},"PeriodicalIF":0.5,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12818459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Patent Foramen Ovale (PFO) Can Cause Trouble-A Misplacement of Pacemaker Lead Into the Left Ventricle.","authors":"Ayman Helal, Ibrahim Antoun, Mohammed El-Din, Mohsin Farooq","doi":"10.1155/cric/6816373","DOIUrl":"10.1155/cric/6816373","url":null,"abstract":"<p><p>Misplacement of pacemakers lead into the left ventricle (LV) is a rare but clinically important complication, often facilitated by unrecognized intracardiac shunts such as a patent foramen ovale (PFO). Early recognition is essential to avoid systemic embolization and ensure safe device function. We report a man in his 70s with a background of bioprosthetic aortic valve replacement, coronary bypass grafting, hypertension, chronic kidney disease, Parkinson's disease, and prostate cancer, who underwent permanent pacemaker implantation for symptomatic sinus pauses. Follow-up echocardiography 1 year later, performed as part of surveillance of his aortic valve prosthesis, unexpectedly revealed that the ventricular lead had crossed a PFO and was positioned in the LV via the mitral valve. His 12-lead ECG demonstrated a right bundle branch block-like paced morphology, raising suspicion of LV pacing. The patient remained asymptomatic with no evidence of systemic embolization. He was anticoagulated with apixaban and subsequently underwent successful lead extraction and repositioning into the right ventricle (RV). Correct RV placement was confirmed using multiple fluoroscopic views, particularly the left anterior oblique (LAO) projection and by postprocedure ECG, chest x-ray, and echocardiogram. This case underlines the importance of careful assessment of paced ECG morphology, fluoroscopic views during implantation (especially LAO), and postimplant imaging to confirm lead location. Suspicion should be raised when an RBBB-like QRS morphology is observed during RV pacing. Timely recognition and management with anticoagulation, followed by extraction and repositioning, can prevent potentially devastating complications. Operators should remain vigilant for inadvertent LV lead placement, particularly in patients with unrecognized PFO. Routine use of multiple fluoroscopic projections and correlation with ECG and echocardiography can aid early diagnosis and improve procedural safety.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"6816373"},"PeriodicalIF":0.5,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12809048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of <i>Corynebacterium diphtheriae</i> Native Mitral and Tricuspid Valve Infective Endocarditis Complicated by Shower Emboli.","authors":"Sara Mashayekan, Tiffany Chow, Julia Gupta, Gary Huang","doi":"10.1155/cric/8832570","DOIUrl":"10.1155/cric/8832570","url":null,"abstract":"<p><p>Infective endocarditis is a rare phenomenon that may have devastating consequences. While uncommon, the spectrum of causative organisms can include <i>Corynebacterium</i> species. <i>Corynebacterium diphtheriae</i> endocarditis bears a high potential for systemic complications and overall mortality. We present a case of mitral and tricuspid native valve endocarditis caused by <i>C. diphtheriae</i> in an immunocompetent patient and highlight the severe manifestations of this condition.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"8832570"},"PeriodicalIF":0.5,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12797461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}