Noura Ayoubi, Zaydi Javeed, Raymond Cutro, Brooke T Baldwin
{"title":"Pyoderma Gangrenosum following Pacemaker Implantation: A Case Report and Review of Literature.","authors":"Noura Ayoubi, Zaydi Javeed, Raymond Cutro, Brooke T Baldwin","doi":"10.1155/2019/8010895","DOIUrl":"https://doi.org/10.1155/2019/8010895","url":null,"abstract":"<p><p>Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by noninfectious, inflammatory, ulcerating lesions. Pathergy can be seen in these patients, whereby minor trauma or surgery can result in the development of PG ulcerations. Here, we present a case of PG following pacemaker implantation. A 76-year-old male with a history of rheumatoid arthritis presented to the cardiology team with symptomatic bradycardia. Indications for implantation were met, and the procedure was performed in a routine fashion. The patient returned to clinic for follow-up four days later, complaining of pain at the incision site, coupled with erythema and purulent drainage. Consultations with an infectious disease specialist and a dermatologist were requested, and the diagnosis of pyoderma gangrenosum was considered. The patient underwent device removal and received systemic corticosteroids at a dose of 1 mg/kg prednisone with complete lesion healing in 3 weeks. While being maintained on steroids, the patient underwent reimplantation of a new pacemaker on the contralateral side without complication and had a normal postoperative course. We present this case report, along with the review of literature, in order to highlight the multidisciplinary approach to management, which requires dermatologic treatment in order to achieve pacemaker success.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2019 ","pages":"8010895"},"PeriodicalIF":0.6,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/8010895","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37449340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erind Gjermeni, Andreas Bollmann, Gerhard Hindricks, Andreas Müssigbrodt
{"title":"Flecainide-Associated Cardiogenic Shock in a Patient with Atrial Fibrillation.","authors":"Erind Gjermeni, Andreas Bollmann, Gerhard Hindricks, Andreas Müssigbrodt","doi":"10.1155/2019/4820652","DOIUrl":"https://doi.org/10.1155/2019/4820652","url":null,"abstract":"<p><p>Flecainide is a frequently used antiarrhythmic drug, recommended by current guidelines as a first-line treatment option for restoring and maintaining sinus rhythm in patients with atrial fibrillation and no significant structural heart disease. In overdose, it can induce severe cardiogenic shock. Cardiogenic shock after a therapeutic dose of flecainide in patients without contraindication has not yet been reported in literature. <i>Case Summary</i>. We report a case of flecainide-associated cardiogenic shock in a 52-year-old woman with paroxysmal atrial fibrillation after a therapeutic dose of flecainide. Pharmacological cardioversion of symptomatic tachyarrhythmic atrial fibrillation with flecainide was unsuccessful and shortly after, she developed cardiogenic shock with severely reduced LVEF. Electrical cardioversion was also unsuccessful. Coronarography was unremarkable, and the cardiac MRI showed no signs of inflammation or fibrosis. After amiodarone loading, she converted to SR. This rare but severe complication despite adequate treatment could be explained by increased susceptibility to negative inotropic effect of flecainide as a consequence of marked tachycardia. Therefore, cautious monitoring after new administration of flecainide or the administration of a higher dose is advisable.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2019 ","pages":"4820652"},"PeriodicalIF":0.6,"publicationDate":"2019-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/4820652","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37449337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Reza, Jessica L. Chowns, A. Marzolf, Jessica Kim, L. Levine, G. Supple, A. Owens
{"title":"Antepartum Diagnosis and Management of Lamin A/C Disease","authors":"N. Reza, Jessica L. Chowns, A. Marzolf, Jessica Kim, L. Levine, G. Supple, A. Owens","doi":"10.1155/2019/3512706","DOIUrl":"https://doi.org/10.1155/2019/3512706","url":null,"abstract":"Lamin A/C cardiac disease is a genetic cardiomyopathy and arrhythmia syndrome caused by alterations in the function of the nuclear lamin A and C proteins. It is inherited in an autosomal dominant manner and usually presents in mid- to late adulthood with atrioventricular conduction abnormalities, atrial and ventricular arrhythmias, biventricular dysfunction, and advanced heart failure. While rare, women of childbearing age can exhibit an aggressive disease course, and appropriate risk stratification and management are critical. Here, we present a case of newly diagnosed lamin A/C cardiac disease in a pregnant woman.","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/3512706","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41749538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simran Gupta, Ricky Ayala, Aakash Desai, Viraj I Modi, Robert J Nardino
{"title":"Left Atrial Myxoma Presenting as Lateral Medullary (Wallenberg's) Syndrome.","authors":"Simran Gupta, Ricky Ayala, Aakash Desai, Viraj I Modi, Robert J Nardino","doi":"10.1155/2019/5610213","DOIUrl":"https://doi.org/10.1155/2019/5610213","url":null,"abstract":"<p><p>Myxomas are benign, primary tumors of the heart. Atrial myxomas can present with a variety of clinical features including dyspnea, orthopnea, pulmonary edema, and pulmonary or systemic emboli. Constitutional symptoms such as fever and weight loss may also be present. We report the case of a young female presenting with headache, facial numbness, and vertigo, who was found to have a posterolateral medullary stroke secondary to a large left atrial cardiac myxoma.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2019 ","pages":"5610213"},"PeriodicalIF":0.6,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/5610213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37449338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avik Ray, Ahmad Najmi, Gaurav Khandelwal, Balakrishnan Sadasivam
{"title":"Ticagrelor-Induced Prolongation of the QTc Interval.","authors":"Avik Ray, Ahmad Najmi, Gaurav Khandelwal, Balakrishnan Sadasivam","doi":"10.1155/2019/5984847","DOIUrl":"https://doi.org/10.1155/2019/5984847","url":null,"abstract":"<p><strong>Background: </strong>Ticagrelor has been accepted as a class I antiplatelet agent in patients undergoing percutaneous coronary angioplasty (PTCA). There have been cases reported on ticagrelor being associated with various cardiac conduction defects. But there is no evidence of QTc prolongation associated with the drug as of yet.</p><p><strong>Case presentation: </strong>A 64-year-old male who underwent PTCA was given ticagrelor. A baseline electrocardiogram (ECG) showed a QTc of 402 ms. He returned after 1.5 months with complaints of shortness of breath. An ECG revealed a prolonged QTc of 468 ms. Ticagrelor was discontinued in view of ticagrelor-induced dyspnea and the patient was started on clopidogrel. The other medications were kept unchanged. The patient returned after a month without any complaints. A follow-up ECG showed a reduced QTc of 425 ms.</p><p><strong>Conclusion: </strong>We present a case of ticagrelor-induced QTc prolongation. To our knowledge, this is the first case to be reported on the same. The Naranjo algorithm for causality assessment gave a total score of 6 indicating that the adverse drug reaction falls under the <i>probable</i> category.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2019 ","pages":"5984847"},"PeriodicalIF":0.6,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/5984847","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37449339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Incidental Diagnosis of Rheumatic Mitral Stenosis and Secundum Atrial Septal Defect (Lutembacher's Syndrome) in a Young Woman","authors":"M. Alam, Md Fakhrul Islam Khaled","doi":"10.1155/2019/9402987","DOIUrl":"https://doi.org/10.1155/2019/9402987","url":null,"abstract":"Lutembacher's syndrome is a rare cardiovascular defect comprising of mitral stenosis and atrial septal defect. A combination of acquired mitral stenosis and congenital atrial septal defect is the most well-recognized pattern. As atrial septal defect acts as a pressure relieving gateway, signs and symptoms of mitral stenosis may be attenuated and/or delayed in such patients. We have presented a case with Lutembacher's syndrome that was incidentally diagnosed as having such defect during outpatient check-up for upper respiratory infection.","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/9402987","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43927541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Alam, Linle Hou, D. James, K. Mody, D. Iyer, A. Ghaly, J. Almendral
{"title":"A Rare Case of Chylothorax after Heart Transplantation","authors":"A. Alam, Linle Hou, D. James, K. Mody, D. Iyer, A. Ghaly, J. Almendral","doi":"10.1155/2019/2049704","DOIUrl":"https://doi.org/10.1155/2019/2049704","url":null,"abstract":"Chylothorax is an exceedingly rare but serious complication of orthotopic heart transplantation (OHT). Prompt diagnosis and appropriate management are essential for a good outcome. Management is similar to that of nontransplant patients, but special attention must be given to patients' nutritional and immunological status. Relevant literature on this topic is limited. We describe our experience in the management of chylothorax after OHT and provide a summary of reported cases of this complication after isolated heart and combined heart/lung transplant.","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/2049704","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48912844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unusual Cause of Dyspnea and Thoracic Pressure","authors":"Claire Chakkalakal, R. Jorbenadze, M. Gawaz","doi":"10.1155/2019/2574858","DOIUrl":"https://doi.org/10.1155/2019/2574858","url":null,"abstract":"There is a high prevalence of hepatic cysts in the general population. Simple cysts are most of the times asymptomatic and are usually detected incidentally on ultrasonography, computed tomography, or magnetic resonance imaging. Symptoms may range from abdominal discomfort and pain, early satiety, dyspepsia, nausea, and vomiting to jaundice and portal hypertension due to obstruction of adjacent structures. Complications include spontaneous hemorrhage, infection, thrombosis, and atrophy of surrounding hepatic tissue. We present a unique case of a middle-aged patient with acute onset of dyspnea and thoracic pressure due to compression of the right ventricle by a large hepatic cyst.","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/2574858","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41412687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Shafiq, Fatima Samad, E. Roberts, J. Levin, U. Nawaz, A. Tajik
{"title":"Squamous Cell Carcinoma of the Tongue with Metastasis to Myocardium: Report of a Case and Literature Review","authors":"A. Shafiq, Fatima Samad, E. Roberts, J. Levin, U. Nawaz, A. Tajik","doi":"10.1155/2019/1649580","DOIUrl":"https://doi.org/10.1155/2019/1649580","url":null,"abstract":"This is a case of a 43-year-old man who in 2014 was diagnosed with oral squamous cell carcinoma involving the tongue. He underwent extensive surgery that involved right tongue cancer resection and reconstruction with a free flap graft from his right forearm. He then was started on chemotherapy and radiation. Surveillance computed tomography in December 2016 showed a cardiac lesion in the left ventricular apex, which was confirmed by further echocardiography and cardiac magnetic resonance imaging. A biopsy of the mass revealed metastatic squamous cell carcinoma. He was deemed to not be a surgical candidate and continued on palliative chemotherapy. The patient had a very poor prognosis and eventually succumbed to the disease, highlighting the importance of surveillance imaging in such cases. A high index of suspicion on the part of the physician is needed to help in the early identification of these patients.","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/1649580","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44763711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infective Aortic Valve Endocarditis Causing Embolic Consecutive ST-Elevation Myocardial Infarctions","authors":"Kanksha Peddi, A. Hsu, Tomas H Ayala","doi":"10.1155/2019/2487616","DOIUrl":"https://doi.org/10.1155/2019/2487616","url":null,"abstract":"ST-elevation myocardial infarction (STEMI) is a rare and potentially fatal complication of infective endocarditis. We report the ninth case of embolic native aortic valve infective endocarditis causing STEMI and the first case to describe consecutive embolisms leading to infarctions of separate coronary territories. Through examination of this case in the context of the previous eight similar documented cases in the past, we find that infective endocarditis of the aortic valve can and frequently affect more than a single myocardial territory and can occur consecutively. Further, current treatment modalities for embolic infective endocarditis causing acute myocardial infarction are limited and unproven. This index case illustrates the potential severity of complications and the challenges in developing standardized management for such patients.","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/2487616","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42099198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}