{"title":"The Intersection of Hip Preservation and Sports Medicine.","authors":"Andrea M Spiker","doi":"10.1177/03635465251376961","DOIUrl":"https://doi.org/10.1177/03635465251376961","url":null,"abstract":"","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"38 1","pages":"2797-2798"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenneth Mautner,Jarred M Kaiser,Blake Boggess,Josh Hackel,Chad Kurtenbach,Benjamin Noonan,Neeta Shenvi,Kirk A Easley,Gregory D Myer,Prathap Jayaram,Michael Gottschalk,Scott Boden,Hicham Drissi
{"title":"Autologous Cell Injections for Knee Osteoarthritis Display Greater Responsiveness Than Allogenic Cellular Products and Corticosteroids in a Sex-Dependent Manner.","authors":"Kenneth Mautner,Jarred M Kaiser,Blake Boggess,Josh Hackel,Chad Kurtenbach,Benjamin Noonan,Neeta Shenvi,Kirk A Easley,Gregory D Myer,Prathap Jayaram,Michael Gottschalk,Scott Boden,Hicham Drissi","doi":"10.1177/03635465251365521","DOIUrl":"https://doi.org/10.1177/03635465251365521","url":null,"abstract":"BACKGROUNDAge-related knee osteoarthritis (KOA) is a debilitating and progressive whole-joint disease. Despite the increased use of cell-based therapies in clinical practice to alleviate KOA symptoms, there lacks robust evidence to guide their clinical utility. We recently reported the results of our randomized controlled trial comparing corticosteroid injections (CSI) to cell-based therapies of bone marrow aspirate concentrate (BMAC), stromal vascular fraction (SVF), and allogenic umbilical cord tissue in 480 patients with Kellgren-Lawrence grade 2 to 4 KOA, finding improvements in all groups at 1 year with no statistically significant differences between groups. Here, we further examine these data from our clinical trial using a responder/nonresponder approach.HYPOTHESISPatients receiving a single injection of a cell-based therapy are more likely to be classified as responders than those receiving a CSI based on pain outcomes at 12 months.STUDY DESIGNRandomized controlled trial; Level of evidence, 2.METHODSWe performed an analysis of 381 patients who completed 12 months' follow-up. Responders were defined as patients with a ≥25% improvement in pain scores on the visual analog scale (VAS) or Knee Injury and Osteoarthritis Outcome Score (KOOS).RESULTSOur hypothesis was conditionally confirmed, with BMAC having a higher response rate than a CSI. The overall responder rate across all treatment methods at 12 months was 58.5% for the VAS and 44.9% for the KOOS. The adjusted odds ratio (aOR) of responder status according to the VAS for BMAC relative to CSI was 2.02 (95% CI, 1.09-3.76). Subgroup analyses identified the heterogeneity of treatment by sex. Male patients had higher odds of a positive response to cellular injections according to the VAS (aOR, 5.18 [95% CI, 1.93-13.85] for BMAC; aOR, 3.34 [95% CI, 1.23-9.06] for SVF; aOR, 2.85 [95% CI, 1.09-7.39] for umbilical cord tissue) relative to CSI. A higher proportion of female than male patients responded to CSI. Of the evaluated therapies, BMAC had the highest percentage of responders. Male patients, particularly those aged <60 years, responded more favorably to BMAC and SVF over other therapies.CONCLUSIONIn addition to comparing the mean outcomes of treatment groups to one another, comparing the proportion of patients in treatment groups who reach a specific improvement threshold, that is, \"responders,\" can provide additional insight into which cellular therapies are most beneficial. The current results indicate that we can improve outcomes and guide the robust design of future clinical trials by identifying patient populations that are most likely to respond favorably to cellular and noncellular injections. This is a first step in personalized (precision-based) medicine for KOA.REGISTRATIONNCT03818737 (ClinicalTrials.gov).","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"17 1","pages":"3635465251365521"},"PeriodicalIF":0.0,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brandon A Young,James C Dawahare,Eric H Lin,Cailan L Feingold,Joseph N Liu,Austin V Stone
{"title":"Reporting Bias Prevalence in Systematic Reviews and Meta-analyses on Trochleoplasty: A Systematic Review.","authors":"Brandon A Young,James C Dawahare,Eric H Lin,Cailan L Feingold,Joseph N Liu,Austin V Stone","doi":"10.1177/03635465251337755","DOIUrl":"https://doi.org/10.1177/03635465251337755","url":null,"abstract":"BACKGROUNDAbstracts of systematic reviews and meta-analyses offer an efficient way to digest the full text, however; abstracts that contain spin, defined as reporting greater efficacy or safety of the experimental treatment than is supported by the results, can negatively affect clinical decisions.PURPOSE/HYPOTHESISThe purpose of this study was to identify and analyze the incidence and types of spin present in systematic reviews and meta-analyses of trochleoplasty procedures while also determining if any identifiable patterns of spin exist. It was hypothesized that abstracts of systematic reviews and meta-analyses on trochleoplasty would contain spin elements.STUDY DESIGNSystematic review; Level of evidence, 4.METHODSThis study was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Peer-reviewed articles were collected from the PubMed, Scopus, Web of Science, and Google Scholar databases as of January 2025. Inclusion criteria were systematic reviews or meta-analyses assessing trochleoplasty. Quality was assessed using AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews Version 2). Two independent authors examined the incidence of the 15 most severe categories of spin. The Fisher exact test with a 95% confidence interval was used to examine associations between spin type and various study characteristics.RESULTSTwenty studies met inclusion criteria, and 9 were meta-analyses. All studies contained at least 1 type of spin (median, 1; range, 1-5). There were no significant associations between spin type or study characteristics, including PRISMA adherence. The most common type of spin was type 5 (conclusion claims the beneficial effect of the experimental treatment despite a high risk of bias in primary studies), which was observed in 10 (50.0%) articles.CONCLUSIONReporting bias is highly prevalent in many abstracts of systematic reviews and meta-analyses on trochleoplasty. When present, spin in the abstracts of the reviewed studies inappropriately favored safety, beneficial effects, and efficacy of the experimental treatment. These findings emphasize the need for clinicians to assess full-text articles regarding trochleoplasty as results presented in abstracts may frequently be misleading. The authors recommend the addition of spin bias evaluation to the PRISMA abstract checklist to help authors recognize and avoid spin in future abstracts of systematic reviews and meta-analyses.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"40 1","pages":"3635465251337755"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145127137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patrick J Tansey,David S Clark,Verdinand C B Ruelos,Robert W Lindeman,Jeremy S Somerson
{"title":"Arthroscopic Bankart Repair With Remplissage Results in Low Recurrent Instability Rates Without Reducing Shoulder Range of Motion at Midterm Follow-up: A Systematic Review of Studies With Minimum 5-Year Outcomes.","authors":"Patrick J Tansey,David S Clark,Verdinand C B Ruelos,Robert W Lindeman,Jeremy S Somerson","doi":"10.1177/03635465251324930","DOIUrl":"https://doi.org/10.1177/03635465251324930","url":null,"abstract":"BACKGROUNDAnterior shoulder instability remains a frequent occurrence in the young, active patient. Arthroscopic remplissage in addition to anteroinferior labral (Bankart) repair is a common treatment to address subcritical bone loss and decrease recurrent dislocation. Despite increasing use, concerns remain about the long-term outcomes of remplissage given its nonanatomic nature and relative novelty.PURPOSETo systematically review published literature to assess functional outcomes, range of motion, recurrence rates, and subsequent revision rates after arthroscopic Bankart repair with remplissage for treatment of anterior shoulder instability with minimum 5-year follow-up.STUDY DESIGNSystematic review; Level of evidence, 4.METHODSTwo independent reviewers performed a literature search based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, using the Scopus, PubMed, and Cochrane Library databases. Clinical studies reporting functional outcomes and recurrence data at a minimum of 5 years after arthroscopic Bankart repair and remplissage for shoulder instability were included for analysis.RESULTSThree studies including 144 shoulders met the inclusion criteria. The mean clinical follow-up was 104 months (9 years), with all patients having a minimum 60 months (5 years) of follow-up. Of the included patients, 77% were male and the mean age was 29 years (range, 15-72 years), with 51% participating in contact sports. All patients had glenoid bone loss <25%. The mean Rowe score increased from 49 to 97 (P < .001). No difference was found in preoperative versus postoperative forward elevation (171° vs 176°; P = .09) or external rotation at 90° of abduction (90° vs 86°; P = .09). The overall rate of recurrent instability events was 10%, with 8% of patients having a repeat dislocation, 4% undergoing repeat operation, and 76% returning to sport.CONCLUSIONIn patients who had recurrent instability with an engaging Hill-Sachs lesion and subcritical glenoid bone loss, arthroscopic Bankart repair with remplissage showed excellent functional outcomes without restricting range of motion in published literature with minimum 5-year follow-up. The recurrent instability and dislocation rates remain lower than the reported rates after isolated Bankart repair. Further reports are needed to determine the clinical outcomes at long-term follow-up.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"19 1","pages":"3635465251324930"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145127174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yong-Beom Park,Seul Ki Lee,Kang-Il Kim,Je-Hyun Yoo,Taehoon Jung,Jun-Ho Kim
{"title":"Microfragmented Adipose Tissue as an Alternative to Platelet-Rich Plasma for Intra-articular Injection in Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.","authors":"Yong-Beom Park,Seul Ki Lee,Kang-Il Kim,Je-Hyun Yoo,Taehoon Jung,Jun-Ho Kim","doi":"10.1177/03635465251337759","DOIUrl":"https://doi.org/10.1177/03635465251337759","url":null,"abstract":"BACKGROUNDIntra-articular (IA) injections of orthobiologics, such as platelet-rich plasma (PRP) and microfragmented adipose tissue (MFAT), have recently gained attention as treatments for knee osteoarthritis (OA). However, clinical evidence supporting their use remains limited.PURPOSETo evaluate the effectiveness and safety of IA injections of PRP and MFAT in patients with knee OA and to compare these 2 treatment modalities.STUDY DESIGNSystematic review and meta-analysis; Level of evidence, 2.METHODSA systematic search was conducted in the MEDLINE, Embase, and Cochrane Library databases to identify randomized controlled trials assessing the efficacy and safety of PRP or MFAT injections in knee OA. Outcomes included pain relief (measured by the 100-mm visual analog scale), functional improvement (assessed by the Knee injury and Osteoarthritis Outcome Score and International Knee Documentation Committee subjective score), and safety (assessed by procedure-related adverse events). The minimal clinically important difference was used to evaluate the clinical significance of the treatments, and a meta-analysis was performed to compare PRP and MFAT. Methodological quality was assessed using the Modified Coleman Methodology Score.RESULTSSix randomized controlled trials were included in the analysis. Both PRP and MFAT achieved minimal clinically important difference in most clinical outcomes up to 12 months after injection. The meta-analysis revealed comparable results for pain relief, functional improvement, and safety between the MFAT and PRP groups from 1 to 24 months after treatment. However, at the 6-month mark, MFAT demonstrated a small but statistically significant advantage over PRP in most clinical outcomes. The median Modified Coleman Methodology Score was 73 (range, 70-75).CONCLUSIONIA injections of PRP and MFAT both provided significant clinical benefits and were safe for treating knee OA over a 12-month period. Although no substantial differences were observed between the 2 treatments in most follow-up periods, MFAT showed slightly better pain relief and functional improvement at 6 months. However, further research is needed to confirm these findings and guide clinical practice.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"100 1","pages":"3635465251337759"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145127138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Pintore,Cyril Brossier,Pierre-Henri Vermorel,Bertrand Boyer,Rémi Philippot,Thomas Neri
{"title":"Femoral Malpositioning of Anterolateral Ligament Reconstruction Is a Significant Risk Factor for Anterior Cruciate Ligament Graft Failure.","authors":"Andrea Pintore,Cyril Brossier,Pierre-Henri Vermorel,Bertrand Boyer,Rémi Philippot,Thomas Neri","doi":"10.1177/03635465251376586","DOIUrl":"https://doi.org/10.1177/03635465251376586","url":null,"abstract":"BACKGROUNDThe femoral attachment of the anterolateral ligament (ALL) reported by anatomic studies is posterior and proximal to the lateral femoral epicondyle.PURPOSETo assess the femoral positioning of the ALL graft while performing a percutaneous technique and evaluate the correlation between this positioning and the graft rupture rate, as well as clinical and functional outcomes.STUDY DESIGNCohort study; Level of evidence, 3.METHODSA total of 211 patients undergoing combined anterior cruciate ligament (ACL) and ALL reconstruction were included. Radiological measurements, Knee injury and Osteoarthritis Outcome Score (KOOS), International Knee Documentation Committee (IKDC) score, and graft failure rate were collected at 24 months after surgery.RESULTSThe rate of anatomic positioning of ALL femoral anchors was 79.1% (n = 167). The mean proximal and posterior distances relative to the ALL anatomic femoral position were 1.4 ± 2.8 mm and 0.2 ± 0.2 mm, respectively. The rate of outliers, defined as >5 mm from the anatomic position, was 20.85% (n = 44). The mean KOOS and IKDC score were 84 ± 10.9 and 80.1 ± 11.3, respectively. No statistically significant difference in KOOS and IKDC score was observed between the group of patients with anatomic positioning and the group of outliers (P = .1). The rate of ACL rerupture for all patients was 3.79% (n = 8). Of these, 87.5% (n = 7) were outliers. The correlation between ALL femoral malpositioning and ACL rerupture was statistically significant (P < .00001).CONCLUSIONIndependent ALL reconstruction while performing a percutaneous technique enabled anatomic positioning of the ALL graft in 79% of cases. The femoral malpositioning was correlated with a higher ACL graft rerupture rate but not with a decrease in the functional outcomes.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"57 1","pages":"3635465251376586"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145134000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linda L Zhang,Pooyan Abbasi,Manaswini Chennoju,Ryan A Hoffman,Adam Z Khan,Joseph A Abboud,Peter S Johnston,Anand M Murthi
{"title":"Distal Radius Allograft Versus Distal Tibia Allograft for Anterior Glenoid Reconstruction: A Biomechanical Comparison.","authors":"Linda L Zhang,Pooyan Abbasi,Manaswini Chennoju,Ryan A Hoffman,Adam Z Khan,Joseph A Abboud,Peter S Johnston,Anand M Murthi","doi":"10.1177/03635465251372525","DOIUrl":"https://doi.org/10.1177/03635465251372525","url":null,"abstract":"BACKGROUNDDistal tibial allograft (DTA) is the most widely used allograft for glenoid reconstruction, but distal radius allograft (DRA) has been proposed as a novel graft option with the advantage of providing a more acute radius of curvature in the anterior-posterior plane that is closer to the native glenoid.PURPOSETo utilize a biomechanical testing model to investigate the glenohumeral contact pressure and kinematics of DRA versus DTA reconstructions of anterior glenoid bone loss.STUDY DESIGNControlled laboratory study.METHODSA total of 11 human cadaveric upper extremities and 11 ankle specimens were utilized. A 30% defect of the anterior glenoid was created and reconstructed with DRA or DTA. A robotic testing system was used to test native joint, DRA, and DTA reconstructions at 60° and 90° of abduction from 0° to 90° of external rotation. Measurements of the center of rotation and humeral head translation were captured using a motion tracking camera. Load and torque data were recorded using a 6-axis load cell. Pressure and contact area were recorded with a pressure mapping sensor pad between the humeral head and the glenoid.RESULTSNo significant differences were observed in contact pressure, contact area, translation, load, or torque between the native and allograft reconstruction conditions at 60° or 90° of abduction. No significant differences were found in contact pressure, contact area, translation, load, or torque between the DRA and DTA reconstruction conditions at 60° or 90° of abduction.CONCLUSIONThe biomechanical data showed comparable compressive forces and glenohumeral joint kinematics between the native joint, DRA, and DTA reconstructions for large anterior glenoid bone loss defects.CLINICAL RELEVANCEThese biomechanical data suggest that DRA represents a promising option for reconstruction of large anterior glenoid bone loss defects. The findings warrant further investigation into the variability of distal radius morphology and future clinical evaluation of DRA reconstruction in the setting of critical glenoid bone loss.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"58 1","pages":"3635465251372525"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145127140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nneoma O. Duru, Austin J. Stoner, Amin M. Alayleh, Dane R.G. Lind, Cassidy Schultz, Nicole S. Pham, Henry B. Ellis, Matthew R. Schmitz, Yi-Meng Yen, Marc A. Tompkins, Theodore Ganley, Molly C. Meadows, Charles Chan, Kevin G. Shea
{"title":"Comparative Analysis of Iliotibial Band Graft Length in Pediatric Anterior Cruciate Ligament Reconstruction: MacIntosh Versus All-Epiphyseal Femoral Drilling Technique","authors":"Nneoma O. Duru, Austin J. Stoner, Amin M. Alayleh, Dane R.G. Lind, Cassidy Schultz, Nicole S. Pham, Henry B. Ellis, Matthew R. Schmitz, Yi-Meng Yen, Marc A. Tompkins, Theodore Ganley, Molly C. Meadows, Charles Chan, Kevin G. Shea","doi":"10.1177/03635465251371321","DOIUrl":"https://doi.org/10.1177/03635465251371321","url":null,"abstract":"Background: Iliotibial band (ITB) grafts yield excellent outcomes for anterior cruciate ligament reconstruction (ACLR) in skeletally immature patients. Because closure of the ITB harvest interval is often not feasible, techniques that allow for shorter ITB grafts may be beneficial. Hypothesis: That the all-epiphyseal femur ITB graft would be significantly shorter than the over-the-top ITB graft. Study Design: Controlled laboratory study. Methods: Six fresh-frozen pediatric knees (mean age, 9.7 years; range, 9-11 years) were used. Surgeons simulated the modified MacIntosh and all-epiphyseal ITB ACLRs using No. 2 suture as a proxy for the ITB graft. A suture was attached at the ITB origin on the Gerdy tubercle and then passed over-the-top on the femur, under the transverse meniscal ligament, and to the metaphyseal anchor point. The length of the suture was measured. The suture was then placed through the all-epiphyseal femoral drill hole, under the transverse meniscal ligament to the same tibial metaphyseal anchor point. Femoral condyle width was recorded, and the relationship between graft length and technique was analyzed using analysis of covariance to adjust for femoral condyle widths. Results: Graft length for the all-epiphyseal ITB ACLR was significantly shorter than that for the modified MacIntosh ITB ACLR, with a mean difference of 26.0 ± 6.0 mm ( <jats:italic>P</jats:italic> < .001). Across both groups, each additional millimeter of condyle width was associated with an increase in graft length by 2.3 mm ( <jats:italic>P</jats:italic> < .001). Mean graft lengths for the modified MacIntosh and all-epiphyseal femur were 173.3 ± 16.5 mm and 147.3 ± 16.0 mm, respectively. Conclusion: The all-epiphyseal femoral technique requires a significantly shorter ITB graft length compared with the modified MacIntosh technique. A nomogram was developed to estimate graft length differences adjusted for condyle width. Future pediatric studies should continue to explore the biomechanics of both graft techniques, as they may provide lateral extra-articular stabilization and reduce ACL reinjury rates. Clinical Relevance: Shortened ITB autograft length may reduce symptoms associated with muscle herniation.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145089713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alonso Figueroa,Tomasz Bugajski,Dillon Humpal,Manickam Kumaravel,Walter Lowe,Payam Zandiyeh
{"title":"Relationship Between Quantitative MRI UTE T2* of ACL Autografts and BMI-Normalized Knee Laxity within the First Year After ACL Reconstruction.","authors":"Alonso Figueroa,Tomasz Bugajski,Dillon Humpal,Manickam Kumaravel,Walter Lowe,Payam Zandiyeh","doi":"10.1177/03635465251368393","DOIUrl":"https://doi.org/10.1177/03635465251368393","url":null,"abstract":"BACKGROUNDThe anterior cruciate ligament reconstruction (ACLR) graft undergoes a remodeling process that affects its structural properties. Ultrashort echo time T2* (UTE-T2*) imaging has been instrumental in examining this process. However, more research is needed on the postoperative relationship between UTE-T2* of the graft and its mechanical properties.PURPOSETo longitudinally examine ACL graft changes after ACLR using UTE-T2* decay coefficients and knee laxity and explore their relationship.STUDY DESIGNCase series; Level of evidence, 4.METHODSA total of 31 patients who underwent ACLR had magnetic resonance imaging of their knees at 1, 6, and 12 months after surgery using a UTE-T2* sequence. Bilateral knee laxity was measured at 6 and 12 months using a GNRB arthrometer (force = 200 N). UTE-T2* coefficients of the graft were calculated using mono- (T2m*) and biexponential (short [T2s*] and long [T2l*]) analyses, and outcomes were normalized to body mass index. Linear mixed models were used to determine longitudinal changes in UTE-T2* and laxity; the Pearson correlation was used to explore the correlations between these outcomes.RESULTST2m* of the graft increased from 1 to 6 months (Δ = 0.092; P = .008), followed by a decrease from 6 to 12 months (Δ = -0.079; P = .021). Regardless of the limb side, a decrease in laxity was detected between 6 and 12 months after surgery (Δ = -0.033; P = .046). Positive correlations between laxity and UTE-T2* were detected at 6 months (T2s*: R = 0.285; P = .025) and 12 months (T2m*: R = 0.532; P < .01; T2s*: R = 0.669; P < .001; T2l*: R = 0.354; P = .034).CONCLUSIONBiexponential analysis of UTE-T2* MRI provides a sensitive tool for detecting structural changes in the graft after ACL reconstruction, reflecting the dynamic process of graft remodeling. Among the decay coefficients assessed, T2s* demonstrates a stronger correlation with postoperative laxity, highlighting its potential as a critical biomarker for monitoring graft integrity over time.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"75 1","pages":"3635465251368393"},"PeriodicalIF":0.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145083488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Austin R Driggers,Andrew C Fry,Kristen C Chochrane-Snyman,John P Wagle,Jeffrey M McBride
{"title":"Effectiveness of Single Leg Isometric Bridge and Nordic Hamstring Exercise Testing for Prediction of Hamstring Injury Risk in Professional Baseball Players.","authors":"Austin R Driggers,Andrew C Fry,Kristen C Chochrane-Snyman,John P Wagle,Jeffrey M McBride","doi":"10.1177/03635465251371789","DOIUrl":"https://doi.org/10.1177/03635465251371789","url":null,"abstract":"BACKGROUNDSeveral investigations have examined various methods of measuring hamstring strength to determine the effectiveness of these tests in predicting hamstring injury (HSI) risk in athletes. However, no previous studies have examined the effectiveness of hamstring strength and interlimb asymmetry utilizing a newly developed modified single leg isometric bridge test (SLIBT) versus a standard Nordic hamstring exercise (NHE) to predict HSI in professional baseball players.PURPOSETo determine whether preseason hamstring strength and interlimb asymmetry measured using a modified SLBIT versus an NHE are associated with future HSI in professional baseball players, as well as if measures of hamstring strength and interlimb asymmetry using the SLIBT are correlated to values from the NHE.STUDY DESIGNCohort study; Level of evidence, 3.METHODSProfessional baseball players (n = 465) from 8 teams affiliated with a single Major League Baseball organization completed a preseason hamstring strength assessment as part of routine athlete monitoring before the 2019, 2021, and 2022 seasons. A total of 38 new HSI events were recorded among 36 players over 751 player-seasons included in the analysis.RESULTSLower hamstring strength levels in subsequent HSI limbs were observed compared with the 2-limb mean hamstring strength of healthy players for the SLIBT (365.1 ± 58.4 vs 390.9 ± 59.6 N; P = .014) and NHE (403.5 ± 90.4 vs 440.5 ± 76.0 N; P = .017). Players with NHE hamstring strength <377 N exhibited a significantly higher risk of HSI (RR, 2.49; 95% CI, 1.18-5.27; P = .027). Logistic regression indicated an inverse relationship between hamstring strength and HSI risk, with each 10-N increase in the SLIBT and NHE corresponding to a 7.4% and 6.2% risk reduction, respectively (with no interaction effects between tests). Interlimb asymmetry measures from both the SBILT and NHE were not indicative of subsequent HSI. Moderate significant correlations (r = 0.33-0.39) were observed for absolute and relative hamstring strength measured utilizing the SLIBT versus the NHE. No significant correlations were found between measures of interlimb asymmetry when assessed by the SBILT versus the NHE.CONCLUSIONThe current investigation indicates that low levels of hamstring strength measured in both the SLIBT and NHE are associated with an increased risk of future HSI. Thus, these measures could be utilized to identify at-risk players and to develop mitigation strategies to limit the rate of HSI and maximize time at play.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"56 1","pages":"3635465251371789"},"PeriodicalIF":0.0,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145083394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}