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One-Year Outcomes Predict 10-Year Outcomes in Patients Undergoing Hip Arthroscopy for Femoroacetabular Impingement 髋关节镜治疗股髋臼撞击患者1年预后预测10年预后
The American Journal of Sports Medicine Pub Date : 2025-05-30 DOI: 10.1177/03635465251342119
Emily Berzolla, Katherine L. Esser, Griffith G. Gosnell, Nathaniel Mercer, Daniel J. Kaplan, Thomas Youm
{"title":"One-Year Outcomes Predict 10-Year Outcomes in Patients Undergoing Hip Arthroscopy for Femoroacetabular Impingement","authors":"Emily Berzolla, Katherine L. Esser, Griffith G. Gosnell, Nathaniel Mercer, Daniel J. Kaplan, Thomas Youm","doi":"10.1177/03635465251342119","DOIUrl":"https://doi.org/10.1177/03635465251342119","url":null,"abstract":"Background: While both short- and long-term outcomes after hip arthroscopy for femoroacetabular impingement syndrome (FAIS) have been reported, the predictive relationship between the two has yet to be established. Purpose: To determine whether the degree of improvement in patient-reported outcomes observed at 1 year postoperatively predicts long-term outcomes at 10 years after primary hip arthroscopy for FAIS. Study Design: Cohort study; Level of evidence, 3 Methods: Patients who underwent primary hip arthroscopy for FAIS by a single surgeon at a single institution with 10-year follow-up were identified. Outcomes were assessed using the modified Harris Hip Score (mHHS) and Nonarthritic Hip Score (NAHS) at baseline and 1, 2, 5, and 10 years postoperatively. Patients were classified as either high improvement (HI) or low improvement (LI) based on if they achieved the median 1-year change in mHHS from baseline. Chart review was performed to collect surgical details such as operative procedures, complications, and revision surgery. Outcomes were compared between groups over time using repeated-measures analysis of variance. Failure rates were determined using Kaplan-Meier and Mantel-Cox log-rank analyses. Results: A total of 129 patients with a mean age of 41.0 ± 13.5 years and mean body mass index of 25.0 ± 4.3 kg/m <jats:sup>2</jats:sup> were included. Both the HI and LI groups demonstrated significant improvement in mHHS and NAHS from baseline at all follow-up time points ( <jats:italic>P</jats:italic> &lt; .001). The HI group had significantly higher outcome scores at all time points up to 10 years after arthroscopy compared with the LI group ( <jats:italic>P</jats:italic> = .018). Additionally, a greater proportion of patients in the HI group achieved the Patient Acceptable Symptom State and minimal clinically important difference compared with the LI group at the 10-year follow-up ( <jats:italic>P</jats:italic> = .018). Rates of overall complications, revision arthroscopy, and conversion to total hip arthroscopy were significantly higher in the LI group ( <jats:italic>P</jats:italic> = .013, <jats:italic>P</jats:italic> = .009, and <jats:italic>P</jats:italic> = .004, respectively). The mean hip survival time after the index operation was shorter for the LI group (11.9 ± 0.5 years) than for the HI group (13.2 ± 0.2 years) ( <jats:italic>P</jats:italic> = .002). Conclusion: Patients who experienced greater improvement in the first year after hip arthroscopy had superior 10-year outcome scores, fewer complications, and lower rates of reoperation compared with those who experienced minimal improvement in the same period.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacologic Mobilization and Chemokine-Directed Recruitment of Mesenchymal Stromal Cells to the Surgically Repaired Rotator Cuff 手术修复后肩袖间充质间质细胞的药理动员和趋化因子定向募集
The American Journal of Sports Medicine Pub Date : 2025-05-30 DOI: 10.1177/03635465251341439
Kevin C. Baker, Mackenzie Fleischer, Michael D. Newton, Lisa Galasso, Leonardo Cavinatto, Kevin M. Weisz, Samantha Hartner, Tristan Maerz, Lindsey Lammlin, Erin A. Baker, Answorth A. Allen, Asheesh Bedi
{"title":"Pharmacologic Mobilization and Chemokine-Directed Recruitment of Mesenchymal Stromal Cells to the Surgically Repaired Rotator Cuff","authors":"Kevin C. Baker, Mackenzie Fleischer, Michael D. Newton, Lisa Galasso, Leonardo Cavinatto, Kevin M. Weisz, Samantha Hartner, Tristan Maerz, Lindsey Lammlin, Erin A. Baker, Answorth A. Allen, Asheesh Bedi","doi":"10.1177/03635465251341439","DOIUrl":"https://doi.org/10.1177/03635465251341439","url":null,"abstract":"Background: Mesenchymal stromal cell (MSC) techniques represent a promising method to enhance the surgical repair of rotator cuff tears. To eliminate the resource-intensive process of cell isolation and culture expansion, a method to recruit endogenous MSCs was investigated in an established rat model of rotator cuff repair. Hypothesis: MSCs can be pharmacologically mobilized from the peripheral blood and recruited to the operative rotator cuff to enhance tendon-bone healing. Study Design: Controlled laboratory study. Methods: The rat model of supraspinatus tendon detachment and acute surgical repair was used to compare the ability of 3 different chemokines (SDF-1β, MIP-3α, and MCP-1) to recruit optically labeled MSCs to the operative shoulder from circulation. Additional experimentation was undertaken to assess the effects of pharmacological MSC mobilization using a combination of a β <jats:sub>3</jats:sub> adrenoreceptor agonist (BRL37344) and a CXCR4 antagonist (AMD3100) on chemokine-directed recruitment to the shoulder. Finally, the effects of this therapeutic strategy on tendon-bone healing were assessed. Results: MCP-1–loaded hydrogels recruited the greatest number of MSCs from circulation. MCP-1–driven MSC recruitment was significantly enhanced by a regimen of subcutaneous BRL37344 and AMD3100. Postmortem micro–computed tomography imaging performed at a 6-week endpoint revealed that local MCP-1 delivery was associated with significant reductions in trabecular spacing and apparent mineral density, and a significant increase in trabecular number, while pharmacological MSC mobilization had no significant effects. MCP-1 delivery was associated with a lower tendon cross-sectional area and a significant increase in percent relaxation ( <jats:italic>P</jats:italic> = .006). Pharmacological MSC mobilization was associated with significantly increased peak stress ( <jats:italic>P</jats:italic> = .039), significantly increased elastic modulus ( <jats:italic>P</jats:italic> = .037), and a nonsignificant increase in both equilibrium stress ( <jats:italic>P</jats:italic> = .057) and ultimate stress ( <jats:italic>P</jats:italic> = .058). Local MCP-1 delivery was associated with significant improvements in tenocyte morphology. Conclusion: Endogenous MSCs can be pharmacologically mobilized into peripheral blood and recruited to the site of rotator cuff repair via local delivery of MCP-1. This therapeutic strategy was associated with improvements in the static and dynamic mechanical properties of the tendon-bone interface. Clinical Relevance: The healing of rotator cuff repairs represents an ongoing clinical challenge in orthopaedic surgery. This study demonstrates a method to use endogenous MSCs to enhance healing of the rotator cuff.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Addition of Remplissage to Arthroscopic Bankart Repair and Effect on Recurrent Instability in Shoulders With Critical Humeral Bone Loss. 在关节镜下Bankart修复中加入remplage及其对肱骨严重丢失的肩部复发性不稳定的影响。
The American Journal of Sports Medicine Pub Date : 2025-05-26 DOI: 10.1177/03635465251340082
Fritz Steuer,Stephen Marcaccio,Ting Cong,Shaquille Charles,Rajiv P Reddy,Sophia McMahon,Albert Lin
{"title":"The Addition of Remplissage to Arthroscopic Bankart Repair and Effect on Recurrent Instability in Shoulders With Critical Humeral Bone Loss.","authors":"Fritz Steuer,Stephen Marcaccio,Ting Cong,Shaquille Charles,Rajiv P Reddy,Sophia McMahon,Albert Lin","doi":"10.1177/03635465251340082","DOIUrl":"https://doi.org/10.1177/03635465251340082","url":null,"abstract":"BACKGROUNDRecent literature has shown that inferior Hill-Sachs extension for on-track shoulders is predictive of recurrent instability after arthroscopic Bankart repair alone. Specifically, there is a high risk for recurrent instability when the lesion extends below the humeral equator on sagittal magnetic resonance imaging. This worrisome inferior extension has been termed \"critical humeral bone loss (CHBL).\" Remplissage has yet to be explored as a potential useful augmentation in patients with CHBL.HYPOTHESISThe addition of remplissage would decrease recurrence rates for Hill-Sachs lesions with inferior extension or CHBL compared with arthroscopic Bankart repair alone in patients with on-track Hill-Sachs lesions.STUDY DESIGNCase series; Level of evidence, 4Methods:Retrospective analysis was performed on the records of patients who underwent primary arthroscopic Bankart repair with or without the addition of remplissage from 2007 to 2021. Off-track shoulders, revision stabilization, glenoid bone loss (GBL) >20%, and those with follow-up <2 years or incomplete medical data were excluded. The primary outcome was recurrent instability, defined as either postoperative dislocation or subluxation. The Hill-Sachs position was measured relative to the humeral axis on sagittal magnetic resonance imaging as previously described. Univariate and multivariate logistic regression analyses were implemented to determine the protective effect of remplissage.RESULTSA total of 219 patients were included for analysis with a mean age of 21.1 years (range, 12.9-40.5 years) and mean follow-up of 7.0 years (range, 2-14.4 years); 44 patients (20%) underwent remplissage in addition to arthroscopic Bankart. In multivariate analysis, remplissage significantly reduced the risk of recurrent instability (OR, 0.06; P = .002) and CHBL was a significant predictor of recurrent instability (OR, 3.0; P = .029) while adjusting for age, multiple preoperative dislocations, contact athlete status, and percent GBL. When stratified by CHBL, remplissage remained protective (OR, 0.013; P = .007) against recurrent instability.CONCLUSIONThe addition of a remplissage for CHBL in patients with subcritical GBL and on-track Hill-Sachs lesions reduces the risk of recurrent instability in patients undergoing arthroscopic Bankart repair.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"23 1","pages":"3635465251340082"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Medial Closing Wedge Distal Femoral Osteotomy on Tibial Tuberosity-Trochlear Groove Distance in Patients With Genu Valgum According to Diagnosis (Lateral Osteoarthritis or Patellar Dislocation). 内侧闭合楔形股骨远端截骨术对膝外翻(外侧骨关节炎或髌骨脱位)患者胫骨结节-滑车沟距离的影响。
The American Journal of Sports Medicine Pub Date : 2025-05-26 DOI: 10.1177/03635465251342093
Hyung Jun Park,Hyung Suh Kim,Dong Hun Suh,Jae Gyoon Kim,Kyung-Wook Nha
{"title":"Effect of Medial Closing Wedge Distal Femoral Osteotomy on Tibial Tuberosity-Trochlear Groove Distance in Patients With Genu Valgum According to Diagnosis (Lateral Osteoarthritis or Patellar Dislocation).","authors":"Hyung Jun Park,Hyung Suh Kim,Dong Hun Suh,Jae Gyoon Kim,Kyung-Wook Nha","doi":"10.1177/03635465251342093","DOIUrl":"https://doi.org/10.1177/03635465251342093","url":null,"abstract":"BACKGROUNDMedial closing wedge distal femoral osteotomy (CWDFO) is used to correct valgus deformities and manage lateral osteoarthritis (OA) and patellar dislocation (PD). However, its effect on the tibial tuberosity-trochlear groove (TT-TG) distance remains debated, with limited studies evaluating contributing factors.PURPOSETo determine whether TT-TG distance changes after CWDFO differ by the underlying diagnosis prompting the procedure and to identify preoperative factors influencing the extent of TT-TG distance changes.STUDY DESIGNCase series; Level of evidence, 4.METHODSThis study analyzed 43 knees of 34 patients with valgus deformity who underwent CWDFO, categorized into the lateral OA (n = 14) and PD (n = 29) groups. Radiographic parameters, including the TT-TG distance, were assessed preoperatively and at least 1 year postoperatively. Regression analyses were conducted to identify the factors influencing TT-TG distance changes. A predictive model with 95% confidence intervals determined the thresholds for deviations from the expected values.RESULTSThe TT-TG distance significantly decreased from 14.7 ± 5.1 to 11.5 ± 4.7 mm after CWDFO (P < .001). On average, the TT-TG distance decreased by 21.8% after CWDFO. Changes in the TT-TG distance did not significantly differ by diagnosis (lateral OA: -3.0 ± 2.3 mm; PD: -3.3 ± 4.5 mm; P = .771). The preoperative TT-TG distance and osteotomy type significantly influenced TT-TG distance changes. A higher preoperative TT-TG distance was correlated with a greater reduction (odds ratio, -0.375; P = .001), and biplanar osteotomy showed a more pronounced effect than uniplanar osteotomy (odds ratio, -3.083; P = .013). Patients with preoperative TT-TG distances >23.5 mm demonstrated greater variability in TT-TG distance changes in the predictive model.CONCLUSIONCWDFO effectively reduced the TT-TG distance regardless of the diagnosis. Preoperative TT-TG distance and osteotomy type were key determinants of this reduction. In cases with preoperative TT-TG distances >23.5 mm, TT-TG distance changes demonstrated greater variability, suggesting that radiographic outcomes may deviate from expected values. These findings highlight the need for careful postoperative assessments and consideration of additional procedures in select cases.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"67 1","pages":"3635465251342093"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-Dependent Variation in Cytokine Type and Concentration in Knee Synovial Fluid After Meniscal Injury. 半月板损伤后膝关节滑液细胞因子类型和浓度的年龄依赖性变化。
The American Journal of Sports Medicine Pub Date : 2025-05-23 DOI: 10.1177/03635465251339490
Vishal Sundaram,Katherine L Esser,Luke Schwartz,Larry Chen,Nathaniel P Mercer,Bradley A Lezak,Heath P Gould,Daniel Kaplan,Eric J Strauss
{"title":"Age-Dependent Variation in Cytokine Type and Concentration in Knee Synovial Fluid After Meniscal Injury.","authors":"Vishal Sundaram,Katherine L Esser,Luke Schwartz,Larry Chen,Nathaniel P Mercer,Bradley A Lezak,Heath P Gould,Daniel Kaplan,Eric J Strauss","doi":"10.1177/03635465251339490","DOIUrl":"https://doi.org/10.1177/03635465251339490","url":null,"abstract":"BACKGROUNDMeniscal injuries trigger a local inflammatory response mediated by intra-articular mediators. Proinflammatory cytokines and chemokines can lead to cartilage degradation and subchondral bone changes, contributing to posttraumatic osteoarthritis. The role that age plays in this inflammatory response is unclear.PURPOSETo investigate age-dependent variation in cytokine types and concentrations in knee synovial fluid after meniscal injury.STUDY DESIGNCohort study; Level of evidence, 3.METHODSPatients undergoing arthroscopic knee surgery for isolated meniscal injury were prospectively enrolled between July 2011 and April 2024. Synovial fluid was aspirated from the operative knee, and concentrations of 10 biomarkers were measured. Patients at least 9 years after surgery were invited to complete patient-reported outcome (PRO) surveys. Multivariable linear regression assessed pairwise relationships between age at surgery, log-normalized biomarker concentrations, and PROs, while adjusting for relevant covariates. Conditional process analysis was used to explore age-biomarker relationships, with symptom duration as a moderator and baseline Outerbridge grade as a mediator.RESULTSThe study included 160 patients for biomarker analysis with a mean ± SD age of 50.2 ± 12.5 years. Forty-seven patients who reached a minimum 9 years of follow-up completed PRO surveys. Mean follow-up was 10.2 ± 1.3 years. Regression analysis revealed positive associations between age and log-normalized concentration of preoperative IL-6. Moderator analysis found age to be positively associated with IL-6, VEG-F, and IL-1Ra in chronic meniscal injuries. Mediator analysis found an indirect positive relationship between age and MIP-B, VEGF, and MMP-3 and an indirect negative relationship between age and TIMP-1 and TIMP-2. Preoperative TIMP-1 was positively associated with 10-year Knee injury and Osteoarthritis Outcome Score-Physical Function Short Form score and elevated in treatment responders.CONCLUSIONAge at surgery was associated with higher concentrations of proinflammatory biomarkers and lower concentrations of anti-inflammatory biomarkers in the synovial fluid before meniscal surgery. Anti-inflammatory markers were associated with improved long-term PROs. These findings suggest an age-related intensification of the proinflammatory response and inhibition of the anti-inflammatory response that may contribute to long-term functional decline in older patients after meniscal surgery. There is potential for age-specific immunomodulatory therapeutic strategies to manage inflammation and mitigate the progression toward posttraumatic osteoarthritis in older patients.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"57 1","pages":"3635465251339490"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Current and Former Anabolic-Androgenic Steroid Abuse on the Patellar Tendon. 当前和以前的合成代谢雄激素类固醇滥用对髌骨肌腱的影响。
The American Journal of Sports Medicine Pub Date : 2025-05-23 DOI: 10.1177/03635465251340701
Ann Damgaard,Grith Højfeldt,Olivia Thorsgaard,Yeliz Bulut,Frederik Hvid Linden,Peter Schjerling,Abigail L Mackey,Caroline Kistorp,S Peter Magnusson,Michael Kjær,Rene B Svensson
{"title":"Effect of Current and Former Anabolic-Androgenic Steroid Abuse on the Patellar Tendon.","authors":"Ann Damgaard,Grith Højfeldt,Olivia Thorsgaard,Yeliz Bulut,Frederik Hvid Linden,Peter Schjerling,Abigail L Mackey,Caroline Kistorp,S Peter Magnusson,Michael Kjær,Rene B Svensson","doi":"10.1177/03635465251340701","DOIUrl":"https://doi.org/10.1177/03635465251340701","url":null,"abstract":"BACKGROUNDAnabolic-androgenic steroids (AASs) are synthetic derivatives of testosterone that are abused by athletes to enhance their physical appearance and performance. AAS abusers have an increased risk of tendon ruptures compared with nonusers, and it has been proposed that AASs damage tendon tissue. Only a few human studies have investigated the effect of AASs on tendon tissue, and to our knowledge, there are no data on female sex.PURPOSE/HYPOTHESISThe purpose was to investigate the effect of current and former abuse of AASs on the patellar tendon (PT). It was hypothesized that AASs would not affect tendon tissue.STUDY DESIGNCross-sectional study; Level of evidence, 3.METHODSThis study included recreational athletes with current (female: n = 4; male: n = 18; total: n = 22) or former (female: n = 5; male: n = 7; total: n = 12) AAS abuse and nonusers (female: n = 5; male: n = 9; total: n = 14). The authors investigated the proportion of tendon injuries, PT cross-sectional area by magnetic resonance imaging, mechanical properties by ultrasound, gene expression levels of connective tissue proteins, and cell density by histological staining from tendon biopsy samples.RESULTSThe combined AAS group (both current and former abusers) reported a higher proportion of upper body tendon injuries compared with nonusers (79.4% vs 28.6%, respectively; P = .002). There was no difference in PT cross-sectional area (P = .918) or cell density (fascicular matrix: P = .413; interfascicular matrix: P = .982) between current AAS abusers, former AAS abusers, and nonusers. There was a greater expression of IGF-1 mRNA in current AAS abusers compared with nonusers (P = .043), but there were no group differences in other mRNA targets. Former AAS abusers had significantly higher tendon deformation (P = .030) and strain (P = .026) at common force compared with nonusers. There were no significant differences between male and female participants in the effect of AASs on tendon tissue.CONCLUSIONThese data show that the PT itself was not severely affected by AAS abuse.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"18 1","pages":"3635465251340701"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustained Clinical and Functional Outcomes After Primary Anterior Cruciate Ligament Repair: A Minimum 5-Year Follow-up Study. 原发性前交叉韧带修复后的持续临床和功能结果:一项至少5年的随访研究。
The American Journal of Sports Medicine Pub Date : 2025-05-23 DOI: 10.1177/03635465251340087
Sebastian Conner-Rilk,Gabriel C Goodhart,Fidelius von Rehlingen-Prinz,Jelle P van der List,Kyle N Kunze,Fabian Tomanek,Robert J O'Brien,Gregory S DiFelice
{"title":"Sustained Clinical and Functional Outcomes After Primary Anterior Cruciate Ligament Repair: A Minimum 5-Year Follow-up Study.","authors":"Sebastian Conner-Rilk,Gabriel C Goodhart,Fidelius von Rehlingen-Prinz,Jelle P van der List,Kyle N Kunze,Fabian Tomanek,Robert J O'Brien,Gregory S DiFelice","doi":"10.1177/03635465251340087","DOIUrl":"https://doi.org/10.1177/03635465251340087","url":null,"abstract":"BACKGROUNDPrimary anterior cruciate ligament (ACL) repair (ACLPR) demonstrates promising short-term clinical outcomes in select patients; however, it remains poorly understood as to whether previously reported short-term outcomes are maintained at midterm follow-up.PURPOSETo determine whether short-term (2-year) outcomes are maintained at 5 years after ACLPR, evaluate age-stratified failure and reoperation rates, and identify preoperative risk factors for failure.STUDY DESIGNCase series; Level of evidence, 4.METHODSThis prospective study included the first 113 consecutive patients with proximal (type I/II) ACL tears who underwent ACLPR between 2008 and 2017 with a minimum 5-year follow-up. Failure rates were recorded based on instrumented laxity (&gt;3-mm anterior tibial translation side-to-side difference), pivot-shift grade (grade ≥2), and subjective instability. Patient Acceptable Symptom State thresholds were established based on collected patient-reported outcome measure scores. Logistic regression models were constructed to determine associations with independent risk factors for failure.RESULTSA total of 107 patients (median age, 35.5 years [interquartile range, 22.4-43.1 years]) were available at final follow-up (median, 6.0 years [interquartile range, 5.3-7.0 years]). No significant differences were reported in failure rates between 2- and 5-year follow-up: overall non-age-differentiated: 11.5% versus 15.9%, respectively (P = .34); ≤21 years: 37.0% versus 38.5%, respectively (P = .92); and &gt;21 years: 3.5% versus 8.6%, respectively (P = .16). No failures occurred in patients aged ≤21 years, while 4 failures occurred in patients aged &gt;21 years. Additionally, no significant differences were observed in overall non-age-differentiated reoperation rates (6.2% vs 7.5%, respectively; P = .71) and contralateral ACL injury rates (3.5% vs 4.7%, respectively; P = .67). Clinical outcomes and patient-reported outcome measure scores did not significantly differ between time points, and most patients met Patient Acceptable Symptom State thresholds (88% for International Knee Documentation Committee form, 91% for Lysholm scale, 93% for Forgotten Joint Score-12, and 84% for ACL-Return to Sport after Injury scale; all P &lt; .001). Preoperative risk factor analysis only revealed younger age as negatively impacting ipsilateral ACL failure, as the odds decreased by 12.5% for each year of increasing age (P = .002).CONCLUSIONSustained clinical and functional outcomes for ACLPR were observed between short-term and midterm follow-up, with failure rates of 11.5% and 15.9%, respectively. Although younger age was an important risk factor for ipsilateral ACL failure, with a high failure rate of 37.0% in patients aged ≤21 years at short-term follow-up, no additional failures were observed at midterm follow-up. In contrast, patients aged &gt;21 years experienced modest failure rates, increasing from 3.5% at short-term follow-up to 8.6% at midterm follow-up, with no significant","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"31 1","pages":"3635465251340087"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Midterm Outcomes in Patients After Central Acetabular Decompression for Central Acetabular Stenosis: A Comparison With a Matched Control Group. 髋臼中央减压治疗髋臼中央狭窄患者的中期预后:与匹配对照组的比较
The American Journal of Sports Medicine Pub Date : 2025-05-22 DOI: 10.1177/03635465251338064
Benjamin D Kuhns,Ady H Kahana-Rojkind,Tyler R McCarroll,Yasemin E Kingham,Benjamin G Domb
{"title":"Midterm Outcomes in Patients After Central Acetabular Decompression for Central Acetabular Stenosis: A Comparison With a Matched Control Group.","authors":"Benjamin D Kuhns,Ady H Kahana-Rojkind,Tyler R McCarroll,Yasemin E Kingham,Benjamin G Domb","doi":"10.1177/03635465251338064","DOIUrl":"https://doi.org/10.1177/03635465251338064","url":null,"abstract":"BACKGROUNDCentral acetabular stenosis (CAS), defined as an osteophyte within the acetabular fossa, is associated with higher rates of femoral head chondral damage and, when left untreated, inferior short-term outcomes after hip arthroscopic surgery. Central acetabular decompression (CAD) is an arthroscopic technique to resect the osteophyte and resurface the acetabular fossa to improve contact mechanics of the femoral head.PURPOSEThe primary aim was to provide the 5-year hip preservation rate and patient-reported outcomes in patients undergoing hip arthroscopic surgery for femoroacetabular impingement (FAI) concomitantly with CAD for CAS. A secondary aim was to compare outcomes in patients treated with CAD for CAS to a propensity score-matched control group of patients without CAS.STUDY DESIGNCohort study; Level of evidence, 3.METHODSA surgical registry with prospectively collected data was reviewed for patients who underwent CAD for CAS identified during primary hip arthroscopic surgery for FAI. The primary outcome for the study was conversion to arthroplasty within 5 years postoperatively. Secondary outcomes included revision arthroscopic surgery and patient-reported outcome scores. Multivariate regression analysis was performed to evaluate the risk factors for progression to arthroplasty. A propensity score-matched control group based on preoperative age, sex, body mass index, and Tönnis grade was formed of patients undergoing hip arthroscopic surgery for FAI without CAS to evaluate the differences in outcomes between the 2 groups.RESULTSThere were 155 of 189 eligible patients (82.0%) who had a minimum 5-year follow-up. Within this cohort, the mean age was 45.9 ± 10.8 years, with 90 female patients (58.1%). At the 5-year time point, the arthroplasty-free survivorship rate was 80.6% (125/155). For patients not requiring arthroplasty, significant postoperative improvements were durable (P &lt; .001), with high satisfaction. On multivariate analysis, severe acetabular chondral defects were most predictive of conversion to arthroplasty. The control group of patients with FAI without CAS demonstrated lower rates of chondral damage and higher rates of arthroplasty-free survivorship (P &lt; .01). For patients not requiring arthroplasty, postoperative outcome scores, rates of achieving clinically relevant outcome thresholds, and satisfaction with surgery were comparable between the CAD and control groups.CONCLUSIONPatients with CAS undergoing CAD during primary hip arthroscopic surgery for FAI had durable postoperative improvements and high satisfaction with surgery at a minimum 5-year follow-up. As expected, intraoperative chondral damage rates were significantly greater, and arthroplasty-free survivorship rates were lower, in the CAD group compared with the control group. Nonetheless, 81% of patients undergoing CAD who did not require arthroplasty had significant improvements that were comparable with the control group. We conclude that, with appropriate ","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"10 3 1","pages":"3635465251338064"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Lateral Extra-articular Tenodesis on Anterior Cruciate Ligament Graft Forces and Knee Stability Compared With Slope Reduction Osteotomy in the Setting of Increased Posterior Tibial Slope. 外侧关节外肌腱固定术对前交叉韧带移植物力和膝关节稳定性的影响与在胫骨后坡增加的情况下斜坡复位截骨术的比较。
The American Journal of Sports Medicine Pub Date : 2025-05-21 DOI: 10.1177/03635465251338236
Nicholas J Lemme,Rohit Badida,Janine Molino,Matthew Quinn,Madalyn Hague,Braden C Fleming,Brett D Owens
{"title":"The Effect of Lateral Extra-articular Tenodesis on Anterior Cruciate Ligament Graft Forces and Knee Stability Compared With Slope Reduction Osteotomy in the Setting of Increased Posterior Tibial Slope.","authors":"Nicholas J Lemme,Rohit Badida,Janine Molino,Matthew Quinn,Madalyn Hague,Braden C Fleming,Brett D Owens","doi":"10.1177/03635465251338236","DOIUrl":"https://doi.org/10.1177/03635465251338236","url":null,"abstract":"BACKGROUNDAnterior cruciate ligament (ACL) reconstruction (ACLR) in the presence of excessive posterior tibial slope (PTS) is a well-established risk factor for increased ACL graft forces and a heightened risk of graft failure.PURPOSE/HYPOTHESISThe primary aim of this study was to evaluate whether lateral extra-articular tenodesis (LET) could mitigate the adverse effects of increased PTS on knee kinematics and ACL graft forces, achieving results comparable to those of slope-reducing osteotomy (SRO). It was hypothesized that LET would provide similar improvements in knee stability and graft force reduction to SRO in the presence of increased PTS. A secondary aim was to determine if an ALC injury exacerbates the effect of increased PTS on ACL graft forces and overall knee stability. It was hypothesized that ALC injury would amplify the negative effects of increased PTS.STUDY DESIGNControlled laboratory study.METHODSEight fresh-frozen cadaveric specimens were prepared, excluding those with previous surgery or significant knee pathology. ACLR was performed using a quadrupled hamstring tendon autograft. The effects of LET and SRO were tested at various degrees of PTS (0°, 10°, and 20°). A simulated pivot-shift maneuver was used to measure ACL graft loads, anterior tibial translation (ATT), and internal rotation (IR). Mixed-effects models were utilized to analyze the data.RESULTSIncreasing PTS resulted in significant increases in ACL graft forces (P < .001), ATT (P < .001), and IR (P < .001). LET reduced ACL graft loads by 22.1% at 10° and 36.6% at 20° of PTS. In contrast, a 10° SRO showed only a 2.6% reduction at 10° and 23.9% at 20° of PTS. There were no significant differences in graft forces between the postosteotomy states and LET augmentation states at both 10° and 20° of tibial slope, suggesting equivalent efficacy in reducing graft loads. Additionally, LET significantly decreased graft forces compared with the ALC-sectioned state (P = .019). Finally, ALC sectioning did not significantly increase ACL graft load compared with the ACLR-only condition (P = .320), nor did it exacerbate the effects of increased PTS on ATT and IR.CONCLUSIONLET effectively reduces ACL graft forces and improves knee stability in the presence of increased PTS, performing comparably to or better than SRO under simulated pivot-shift conditions.CLINICAL RELEVANCEThese findings suggest that LET is a viable alternative to SRO, particularly for patients with high PTS undergoing ACLR.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"135 1","pages":"3635465251338236"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Musculoskeletal Findings of the Major League Baseball Combine: A Description of the "Normal" Prospective Professional Baseball Player. 美国职业棒球大联盟组合的肌肉骨骼发现:对“正常”未来职业棒球运动员的描述。
The American Journal of Sports Medicine Pub Date : 2025-05-19 DOI: 10.1177/03635465251339773
Brandon J Erickson,Christopher L Camp,John D'Angelo,Kevin Ma,Liz Hebert,Helen Casey,Derek Papp,Pamela Lund,Hollis Potter,Peter N Chalmers
{"title":"Musculoskeletal Findings of the Major League Baseball Combine: A Description of the \"Normal\" Prospective Professional Baseball Player.","authors":"Brandon J Erickson,Christopher L Camp,John D'Angelo,Kevin Ma,Liz Hebert,Helen Casey,Derek Papp,Pamela Lund,Hollis Potter,Peter N Chalmers","doi":"10.1177/03635465251339773","DOIUrl":"https://doi.org/10.1177/03635465251339773","url":null,"abstract":"BACKGROUNDMajor League Baseball (MLB) recently instituted a combine for their prospective players.PURPOSE/HYPOTHESISThe purpose of this study was to report initial epidemiological findings for both physical examination and imaging findings for the MLB Combine. It was hypothesized that most players would have no significant abnormal physical examination findings, but most would have abnormal findings on their shoulder and elbow magnetic resonance imaging (MRI) scans.STUDY DESIGNDescriptive epidemiology study.METHODSAll players who attended the 2023 MLB Combine were included. History was taken and physical examination was performed by an MLB team physician, and MRI of the shoulder, elbow, cervical spine, and lumbar spine was performed on all players and read by 1 of 2 musculoskeletal radiologists. Physical examination notes and imaging reports were reviewed by the authors and recorded. Data were analyzed separately for pitchers and position players.RESULTSOverall, 219 players (112 pitchers [51%], 107 position players [49%]) were included. The mean age was 20.4 ± 1.5 years. The majority of players (95%) had no current pain or limitations; 54 players (25%) had a history of previous surgery. For pitchers, 18% underwent previous elbow surgery. With regard to MRI, >80% of pitchers had some abnormality within their ulnar collateral ligament (UCL), the majority of which was UCL scarring/remodeling. 70% of pitchers and 60% of position players had evidence of an olecranon osteophyte. Increased signal within the ulnar nerve was common in pitchers (40%) but rare in position players (4%). For the shoulder, 95% of pitchers and 93% of position players had some rotator cuff abnormality (often tendinosis within the supraspinatus and infraspinatus muscles). Also, 75% of pitchers had MRI evidence of a superior labrum anterior to posterior (SLAP) tear, while 24% of position players demonstrated this. Lumbar spine MRI showed that 47% of position players had a disk protrusion and 46% had a previous pars fracture.CONCLUSIONMost baseball players who participated in the 2023 MLB Combine had MRI evidence of rotator cuff abnormalities, and many showed evidence of an olecranon osteophyte. Eighteen percent of pitchers had a previous history of elbow surgery. The majority of pitchers had some abnormality within their UCL and evidence of a SLAP tear on MRI scans.","PeriodicalId":517411,"journal":{"name":"The American Journal of Sports Medicine","volume":"32 1","pages":"3635465251339773"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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