Reporting Bias Prevalence in Systematic Reviews and Meta-analyses on Trochleoplasty: A Systematic Review.

Brandon A Young,James C Dawahare,Eric H Lin,Cailan L Feingold,Joseph N Liu,Austin V Stone
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Abstract

BACKGROUND Abstracts of systematic reviews and meta-analyses offer an efficient way to digest the full text, however; abstracts that contain spin, defined as reporting greater efficacy or safety of the experimental treatment than is supported by the results, can negatively affect clinical decisions. PURPOSE/HYPOTHESIS The purpose of this study was to identify and analyze the incidence and types of spin present in systematic reviews and meta-analyses of trochleoplasty procedures while also determining if any identifiable patterns of spin exist. It was hypothesized that abstracts of systematic reviews and meta-analyses on trochleoplasty would contain spin elements. STUDY DESIGN Systematic review; Level of evidence, 4. METHODS This study was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Peer-reviewed articles were collected from the PubMed, Scopus, Web of Science, and Google Scholar databases as of January 2025. Inclusion criteria were systematic reviews or meta-analyses assessing trochleoplasty. Quality was assessed using AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews Version 2). Two independent authors examined the incidence of the 15 most severe categories of spin. The Fisher exact test with a 95% confidence interval was used to examine associations between spin type and various study characteristics. RESULTS Twenty studies met inclusion criteria, and 9 were meta-analyses. All studies contained at least 1 type of spin (median, 1; range, 1-5). There were no significant associations between spin type or study characteristics, including PRISMA adherence. The most common type of spin was type 5 (conclusion claims the beneficial effect of the experimental treatment despite a high risk of bias in primary studies), which was observed in 10 (50.0%) articles. CONCLUSION Reporting bias is highly prevalent in many abstracts of systematic reviews and meta-analyses on trochleoplasty. When present, spin in the abstracts of the reviewed studies inappropriately favored safety, beneficial effects, and efficacy of the experimental treatment. These findings emphasize the need for clinicians to assess full-text articles regarding trochleoplasty as results presented in abstracts may frequently be misleading. The authors recommend the addition of spin bias evaluation to the PRISMA abstract checklist to help authors recognize and avoid spin in future abstracts of systematic reviews and meta-analyses.
滑骨成形术的系统评价和荟萃分析中的报告偏倚发生率:一项系统评价。
然而,系统综述和荟萃分析的摘要提供了一种消化全文的有效方法;包含自旋的摘要(定义为报告比结果支持的实验治疗更有效或更安全)可能对临床决策产生负面影响。目的/假设本研究的目的是识别和分析滑骨成形术系统评价和荟萃分析中出现的自旋的发生率和类型,同时确定是否存在任何可识别的自旋模式。假设关于滑骨成形术的系统综述和荟萃分析的摘要可能包含自旋元素。研究设计:系统评价;证据等级,4级。方法本研究按照PRISMA(系统评价和荟萃分析的首选报告项目)指南进行。同行评议的文章收集自PubMed、Scopus、Web of Science和b谷歌Scholar数据库,截止到2025年1月。纳入标准是评估滑车成形术的系统评价或荟萃分析。使用AMSTAR 2(评估系统评价的测量工具版本2)评估质量。两位独立作者调查了15种最严重的自转类型的发生率。采用95%置信区间的Fisher精确检验来检验自旋类型与各种研究特征之间的关联。结果20项研究符合纳入标准,9项为荟萃分析。所有研究至少包含1种旋转(中位数为1;范围为1-5)。自旋类型或研究特征(包括PRISMA依从性)之间没有显著关联。最常见的自旋类型是5型(结论声称实验治疗的有益效果,尽管在初步研究中存在较高的偏倚风险),在10篇(50.0%)文章中观察到。结论:在许多关于滑骨成形术的系统综述和荟萃分析摘要中,报告偏倚非常普遍。当被审查的研究摘要出现时,不恰当地偏向于实验性治疗的安全性、有益效果和有效性。这些发现强调临床医生需要评估关于滑囊成形术的全文文章,因为摘要中的结果可能经常会产生误导。作者建议在PRISMA摘要清单中增加自旋偏倚评估,以帮助作者在未来的系统综述和荟萃分析摘要中识别和避免自旋。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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