Psycho-Oncology最新文献

{"title":"Explaining cancer information avoidance comparing people with and without cancer experience in the family.","authors":"Elena Link,&nbsp;Eva Baumann","doi":"10.1002/pon.5826","DOIUrl":"https://doi.org/10.1002/pon.5826","url":null,"abstract":"<p><strong>Objectives: </strong>Cancer information avoidance (CIA) serves as a barrier to preventive efforts. To learn how to combat this barrier, we aim to examine predictors of CIA in populations with and without cancer experience in the family, which are addressed differently in cancer prevention, according to specific informational barriers.</p><p><strong>Methods: </strong>A subsample of people with and without cancer in the family (n = 2,757) of an online survey with a sample stratified for the German population by age, gender, education, and region was conducted via an online access panel. The survey instrument was adapted from the Health Information National Trends Survey. Separate stepwise regression analyses were conducted.</p><p><strong>Results: </strong>Only a comparatively small proportion of the variance in CIA was explained by the predictors, ranging from R²  = .148 for people without cancer experience to R²  = .180 for participants with cancer experience in their family. Across the groups, the findings showed that people who were fatalistic about the risk of cancer, less health literate, who perceived less social pressure to be informed, and were less trusting in information sources more often avoided cancer information.</p><p><strong>Conclusions: </strong>Our findings identify relevant target groups to be addressed and barriers to be removed for cancer communication efforts. Adequate information provision can be supported by programs for fostering health literacy and social network diffusion strategies.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"442-449"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39439290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A patient centred approach to measuring outcomes in psycho-oncology services: The PHQ-8 as a viable alternative to the PHQ-9.","authors":"Caroline Dancyger,&nbsp;Kyle Kelleher,&nbsp;Mark Barrington","doi":"10.1002/pon.5842","DOIUrl":"https://doi.org/10.1002/pon.5842","url":null,"abstract":"Demonstrating both quality and outcomes in health services ensures patients receive care that is safe, effective, patient‐centred, timely, efficient, and equitable. Quality addresses the clinical and operational aspects of care, alongside patient experience. Outcomes typically refer to the measurement of an intervention's impact. Within psychological services, this is often demonstrated through standardised patient reported outcome measures (PROMs). There is no agreed standard for measuring outcome in UK psycho‐oncology services. In 2015, the British Psychological Society published guidance to such services, proposing a network‐level multifactorial approach, that uses a combination of PROMs with normative data from UK cancer populations, that do not place undue burden on patients. Whilst there is variability in PROMs used, the Patient Health Questionnaire‐9 (PHQ‐9), a reliable and valid tool for measuring depressive symptomatology in the cancer population, has been widely adopted. Psycho‐oncology services within North Central and East London have worked together to develop a system wide approach to measuring outcomes.During a reviewof our approach in 2018,we held a focus group to glean service users' views on eight commonly used, standardisedPROMs.We invited service userswhohad received some form of psychological care from our regional psycho‐oncology services to participate; 10 participated. Across all the questionnaires considered, Item‐9 from thePHQ‐9 (‘Thoughts that youwould be better off dead or of hurting yourself in some way’) received the most consistent criticism. Participants described the question as ‘insensitive’, ‘brutal’, and ‘jarring’ in the context of a life‐threatening illness. Additionally, they were confused about what the question was asking (referring to suicidality or self‐harm) and expressed concerns that endorsing such an item may cause them to be labelled as mentally ill by their cancer teams. They understood that some people may have thoughts around suicide or self‐harm, but thought these would be better addressed in a different way, not included in a questionnaire. As this focus group was part of a service evaluation, participants were not asked for personal details, including the reason they had received care from a psycho‐ oncology services or whether they had previously reported suicidality. Whilst the wide spread clinical utility of, and familiarity with, the PHQ‐9 in the UK has been a strong rationale for its continued use,","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"548-550"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39744358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of death-preparedness states with bereavement outcomes for family caregivers of terminally ill cancer patients.","authors":"Fur-Hsing Wen,&nbsp;Wen-Chi Chou,&nbsp;Ming-Mo Hou,&nbsp;Po-Jung Su,&nbsp;Wen-Chi Shen,&nbsp;Jen-Shi Chen,&nbsp;Wen-Cheng Chang,&nbsp;Mei Huang Hsu,&nbsp;Siew Tzuh Tang","doi":"10.1002/pon.5827","DOIUrl":"https://doi.org/10.1002/pon.5827","url":null,"abstract":"<p><strong>Objective: </strong>Death preparedness involves cognitive prognostic awareness and emotional acceptance of a relative's death. Effects of retrospectively assessed cognitive prognostic awareness and emotional preparedness for patient death have been individually investigated among bereaved family caregivers. We aimed to prospectively examine associations of caregivers' death-preparedness states, determined by conjoint cognitive prognostic awareness and emotional preparedness for death, with bereavement outcomes.</p><p><strong>Methods: </strong>Associations of caregivers' death-preparedness states (no-death-preparedness, cognitive-death-preparedness-only, emotional-death-preparedness-only, and sufficient-death-preparedness states) at last preloss assessment with bereavement outcomes over the first two bereavement years were evaluated among 332 caregivers of advanced cancer patients using hierarchical linear models with the logit-transformed posterior probability for each death-preparedness state.</p><p><strong>Results: </strong>Caregivers with a higher logit-transformed posterior probability for sufficient death-preparedness state reported less prolonged-grief symptoms, lower likelihoods of severe depressive symptoms and heightened decisional regret, and better mental health-related quality of life (HRQOL). Caregivers with a higher logit-transformed posterior probability for no-death-preparedness state reported less prolonged-grief symptoms, a lower likelihood of severe depressive symptoms, and better mental HRQOL. A higher logit-transformed posterior probability for cognitive-death-preparedness-only state was associated with bereaved caregivers' higher likelihood of heightened decisional regret, whereas that for emotional-death-preparedness-only state was not associated with caregivers' bereavement outcomes.</p><p><strong>Conclusions: </strong>Caregivers' bereavement outcomes were associated with their preloss death-preparedness states, except for physical health-related QOL. Interventions focused on not only cultivating caregivers' accurate prognostic awareness but also adequately preparing them emotionally for their relative's forthcoming death are actionable opportunities for high-quality end-of-life care and are urgently warranted to facilitate caregivers' bereavement adjustment.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"450-459"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39459864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported lack of energy or feeling depressed 12 months after treatment in men diagnosed with prostate cancer within a population-based registry.","authors":"Jonathan G Bensley,&nbsp;Haryana M Dhillon,&nbsp;Sue M Evans,&nbsp;Melanie Evans,&nbsp;Damien Bolton,&nbsp;Ian D Davis,&nbsp;Lachlan Dodds,&nbsp;Mark Frydenberg,&nbsp;Paul Kearns,&nbsp;Nathan Lawrentschuk,&nbsp;Declan G Murphy,&nbsp;Jeremy L Millar,&nbsp;Nathan Papa","doi":"10.1002/pon.5833","DOIUrl":"https://doi.org/10.1002/pon.5833","url":null,"abstract":"<p><strong>Objective: </strong>Feeling depressed and lethargic are common side effects of prostate cancer (PCa) and its treatments. We examined the incidence and severity of feeling depressed and lack of energy in patients in a population based PCa registry.</p><p><strong>Methods: </strong>We included men diagnosed with PCa between 2015 and 2019 in Victoria, Australia, and enrolled in the Prostate Cancer Outcomes Registry. The primary outcome measures were responses to two questions on the Expanded Prostate Cancer Index Composite (EPIC-26) patient reported instrument: problems with feeling depressed and problems with lack of energy 12 months following treatment. We evaluated associations between these and age, cancer risk category, treatment type, and urinary, bowel, and sexual function.</p><p><strong>Results: </strong>Both outcome questions were answered by 9712 out of 12,628 (77%) men. 981 patients (10%) reported at least moderate problems with feeling depressed; 1563 (16%) had at least moderate problems with lack of energy and 586 (6.0%) with both. Younger men reported feeling depressed more frequently than older men. Lack of energy was more common for treatments that included androgen deprivation therapy than not (moderate/big problems: 31% vs. 13%), irrespective of disease risk category. Both outcomes were associated with poorer urinary, bowel, and sexual functional domain scores.</p><p><strong>Conclusions: </strong>Self-reported depressive feelings and lack of energy were frequent in this population-based registry. Problems with feeling depressed were more common in younger men and lack of energy more common in men having hormonal treatment. Clinicians should be aware of the incidence of these symptoms in these at-risk groups and be able to screen for them.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"496-503"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39497398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient reported factors influencing the decision-making process of men with localised prostate cancer when considering Active Surveillance-A systematic review and thematic synthesis.","authors":"Maggie Cunningham, Mike Murphy, Paul Sweeney, Helen L Richards","doi":"10.1002/pon.5832","DOIUrl":"10.1002/pon.5832","url":null,"abstract":"<p><strong>Objectives: </strong>Outcomes for men with localised prostate cancer managed with Active Surveillance (AS) are similar to outcomes for men who have received Active Treatment. This review explore men's perceptions of the factors that influence their decision-making process when considering AS.</p><p><strong>Method: </strong>A systematic review of studies was conducted up to May 2021, including qualitative studies which explored the decision making of men with localised prostate cancer when considering AS. Evidence was analysed using thematic synthesis.</p><p><strong>Results: </strong>Thirteen papers, including 426 men, met inclusion criteria and were analysed in the review. Approximately half of the men had chosen AS and half had chosen Active Treatment. The choice of AS was not a one-off decision but rather an ongoing behaviour. Four themes were identified and considered within a temporal model: pre-diagnosis representations of cancer and treatment; experience of testing and diagnosis; patient decision making; and emotional adjustment to AS. Key barriers and facilitators to men choosing AS were identified. In deciding whether or not to choose AS, men balanced a desire for quality of life against fear of cancer progression.</p><p><strong>Conclusions: </strong>Both cognitive representations and emotional arousal influence how men decided whether or not to opt for AS. Interventions tailored to elicit and address emotional appraisals of risk, and increase trust in AS protocols, may be of value in helping men to make decisions around treatment for localised prostate cancer.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"388-404"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39483269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Couplelinks online intervention for young couples facing breast cancer: A randomised controlled trial.","authors":"Karen Fergus,&nbsp;Saunia Ahmad,&nbsp;Sandra Gardner,&nbsp;Iana Ianakieva,&nbsp;Deborah McLeod,&nbsp;Joanne Stephen,&nbsp;Wendy Carter,&nbsp;Amanda Periera,&nbsp;Ellen Warner,&nbsp;Jim Panchaud","doi":"10.1002/pon.5836","DOIUrl":"https://doi.org/10.1002/pon.5836","url":null,"abstract":"Young women with breast cancer and their partners are more distressed than couples who are affected later in life. While dyadic interventions in the context of cancer are promising, there are access barriers, particularly for younger couples. This study evaluated Couplelinks, a professionally facilitated, web‐based program designed to help couples improve their conjoint coping.","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"512-520"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39533617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are mind-body therapies effective for relieving cancer-related pain in adults? A systematic review and meta-analysis.","authors":"Nadia Danon, Muaamar Al-Gobari, Bernard Burnand, Pierre-Yves Rodondi","doi":"10.1002/pon.5821","DOIUrl":"10.1002/pon.5821","url":null,"abstract":"<p><strong>Objective: </strong>To assess whether mind-body therapies are effective for relieving cancer-related pain in adults, since at least one-third of adults with cancer are affected by moderate or severe pain.</p><p><strong>Methods: </strong>We searched for all randomized or quasi-randomized controlled trials that included adults (≥18 years) with cancer-related pain who were treated with mind-body therapies (mindfulness, hypnosis, yoga, guided imagery, and progressive muscle relaxation) in MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), Science Citation Index, Web of Science, trials registers, and reference lists. The primary outcome was pain intensity. We calculated the standardized mean differences and 95% confidence intervals (CIs) and assessed the risk of bias.</p><p><strong>Results: </strong>We identified 40 primary studies involving a total of 3569 participants. The meta-analysis included 24 studies (2404 participants) and showed a significant effect of -0.39 (95% CI -0.62 to -0.16) with considerable heterogeneity (I²  = 86.3%, p < 0.001). After we excluded four \"outlier\" studies in sensitivity analyses, the effect size remained significant but weaker. There was a high risk of bias in all studies, for example, performance bias due to lack of participant blinding. Patients in multiple settings were included but many studies were of low quality.</p><p><strong>Conclusions: </strong>Mind-body therapies may be effective in improving cancer pain, but the quality of the evidence is low. There is a need for further high-quality clinical trials.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"345-371"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/47/PON-31-345.PMC9291932.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39437232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences and needs of people with haematological cancers during the COVID-19 pandemic: A qualitative study.","authors":"Nienke Zomerdijk,&nbsp;Michelle Jongenelis,&nbsp;Eva Yuen,&nbsp;Jane Turner,&nbsp;Kathryn Huntley,&nbsp;Andrew Smith,&nbsp;Megan McIntosh,&nbsp;Camille E Short","doi":"10.1002/pon.5819","DOIUrl":"https://doi.org/10.1002/pon.5819","url":null,"abstract":"<p><strong>Objective: </strong>Haematological cancer patients are particularly vulnerable to the effects of COVID-19. In addition to being immunocompromised, pandemic-related travel restrictions have impacted access to treatments and overseas stem cell donations for patients requiring transplantation. Given this vulnerability, people with haematological cancers are at risk of experiencing heightened distress during the pandemic. This study aimed to explore haematological cancer patients' experiences and needs.</p><p><strong>Methods: </strong>Twenty-four Australian haematological cancer patients completed semi-structured interviews exploring their concerns and worries during the pandemic, impact of pandemic on management of disease, access to information and support, lifestyle changes, and attitudes towards emerging models of healthcare during the pandemic. Interview transcripts were thematically analysed.</p><p><strong>Results: </strong>Four themes reflecting the experiences of haematological cancer patients during the pandemic were identified: 'Fears about contracting COVID-19' (behaviour changes to protect health, impact on daily routine and habits, annoyance at dismissive attitude of others toward COVID-19); 'Reduced sense of connection and support' (reduced social support and access to external support services); 'New challenges' (increased financial hardship, worsened health), and; 'Underlying system and communication issues' (access to trusted information, satisfaction/dissatisfaction with care, navigating telehealth). Participants expressed a need for improved access to support services and trusted information.</p><p><strong>Conclusions: </strong>The findings emphasise the additional challenges experienced by haematological cancer patients during the COVID-19 pandemic and their impact on daily life. Results point to the importance of validation of increased distress during periods of uncertainty; reinforcing recommendations about high-quality sources of information; and facilitating access to support services when face-to-face care is limited.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"416-424"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pon.5819","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39417156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer patient satisfaction with health care professional communication: An international EORTC study.","authors":"Juan Ignacio Arraras,&nbsp;Johannes Giesinger,&nbsp;Omar Shamieh,&nbsp;Iqbal Bahar,&nbsp;Michael Koller,&nbsp;Anne Bredart,&nbsp;Karin Kuljanic,&nbsp;Anna Costantini,&nbsp;Eva Greimel,&nbsp;Monika Sztankay,&nbsp;Lisa M Wintner,&nbsp;Marina Carreiro de Sousa,&nbsp;Hiroto Ishiki,&nbsp;Meropi Kontogianni,&nbsp;Maja Wolan,&nbsp;Yuichiro Kikawa,&nbsp;Anne Lanceley,&nbsp;Ioannis Gioulbasanis,&nbsp;Amelie Harle,&nbsp;Dagmara Kuliś","doi":"10.1002/pon.5823","DOIUrl":"https://doi.org/10.1002/pon.5823","url":null,"abstract":"Oncology Departments, Complejo Hospitalario de Navarra, Pamplona, Spain Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria Department of Palliative Care, King Hussein Cancer Center, Amman, Jordan Head, Pain and Palliative Medicine, Cachar Cancer hospital and Research Centre, Silchar, India Center for Clinical Studies, University Hospital Regensburg, Regensburg, Germany Psycho‐Oncology Unit, Institut Curie, Paris, France Psychopathology and Health Process LaboratoryUR4057, Paris University, Paris, France Clinical Hospital Center Rijeka, University of Rijeka, Rijeka, Croatia Psychoncology Unit, Sant’Andrea Universitary Hospital, Rome, Italy Department of Obstetrics and Gynecology, Medical University Graz, Graz, Austria Department of Psychology, Faculty of Human and Social Sciences, University of the Azores, Ponta Delgada, Portugal Center for Research in Neuropsychology and Cognitive‐Behavioral Intervention, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal Department of Palliative Medicine, National Cancer Center Hospital, Tokyo, Japan Department of Nutrition and Dietetics, Harokopio University, Athens, Greece Institute of Medical Sciences, Medical College of Rzeszów University, Rzeszów, Poland Department of Breast Surgery, Kobe City Medical Center General Hospital, Kobe, Japan Department of Women's Cancer, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK Department of Medical Oncology, Animus Kyanus Stavros General Clinic, Larissa, Greece Dorset Cancer Centre, University Hospitals Dorset, Poole, UK Quality of Life Department, European Organisation or Research and Treatment of Cancer, Brussels, Belgium","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"541-547"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39435009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial outcomes of human papillomavirus (HPV)- and non-HPV-related head and neck cancers: A longitudinal study.","authors":"Melissa Henry,&nbsp;Emily Arnovitz,&nbsp;Saul Frenkiel,&nbsp;Michael Hier,&nbsp;Anthony Zeitouni,&nbsp;Karen Kost,&nbsp;Alex Mlynarek,&nbsp;Martin Black,&nbsp;Christina MacDonald,&nbsp;Keith Richardson,&nbsp;Marco Mascarella,&nbsp;Gregoire B Morand,&nbsp;Gabrielle Chartier,&nbsp;Nader Sadeghi,&nbsp;Zeev Rosberger","doi":"10.1002/pon.5803","DOIUrl":"https://doi.org/10.1002/pon.5803","url":null,"abstract":"<p><strong>Objectives: </strong>Human papillomavirus (HPV) has prompted a need to further investigate how this new biomarker changes the head and neck cancer (HNC) psychosocial landscape. This study aimed to: (a) characterize the sociodemographic, psychological, and social profiles of patients with HPV-positive versus -negative squamous cell carcinoma of the head and neck; and (b) identify how HPV status contributes to anxiety and depression (primary outcome), quality of life (QoL), and sexuality needs.</p><p><strong>Methods: </strong>We conducted a prospective longitudinal study of 146 patients newly diagnosed with oral, oropharyngeal, nasopharyngeal, and hypopharyngeal cancer. Seventy-nine patients were HPV-positive and 67 HPV-negative. Patients completed self-administered psychometric measures upon HNC and 3-month follow-up, and Structured Clinical Interviews for DSM Diagnoses.</p><p><strong>Results: </strong>Patients with HPV-negative tumors generally presented with higher anxiety and depression and lower QoL immediately post-HNC diagnosis (<2 weeks) compared to HPV-positive cancers. A Major Depressive Disorder (MDD) immediately post-HNC diagnosis negatively affected patients' anxiety and depression and QoL levels upon diagnosis only when the cancer was HPV-positive. Immediately posttreatment, HPV status was not associated with outcomes. A previous history of suicidal ideation, and upon cancer diagnosis cigarette smoking, anxiety and depression, and feeling close to one's partner were instead explanatory.</p><p><strong>Conclusion: </strong>While patients with HPV-positive HNC generally present with initially lower psychological distress, their vulnerability immediately posttreatment indicates an equal need for support. Head and neck clinics may need to better address MDD, anxiety and depression, a prior history of suicidal ideation, health behavior change, and quality of relationships.</p>","PeriodicalId":516935,"journal":{"name":"Psycho-Oncology","volume":" ","pages":"185-197"},"PeriodicalIF":3.6,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pon.5803","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39891814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}