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Molecular Therapy: Oncology最新文献

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Oncolytic vesicular stomatitis virus alone or in combination with JAK inhibitors is effective against ovarian cancer. 肿瘤溶解性水泡性口炎病毒单独或与 JAK 抑制剂联合使用对卵巢癌有效。
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200826
K. Geoffroy, Victor Mullins-Dansereau, Kim Leclerc-Desaulniers, Mélissa Viens, M. Bourgeois-Daigneault
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引用次数: 0
Translation of Oncolytic Viruses in Sarcoma 肉瘤中的溶瘤病毒翻译
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200822
Steven I. Robinson, Roya Rochell, Velia Penza, Shruthi Naik
{"title":"Translation of Oncolytic Viruses in Sarcoma","authors":"Steven I. Robinson, Roya Rochell, Velia Penza, Shruthi Naik","doi":"10.1016/j.omton.2024.200822","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200822","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"13 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141403695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neoantigen-specific T-cell help outperforms non-specific help in multi-antigen DNA vaccination against cancer 在多抗原 DNA 抗癌疫苗接种中，新抗原特异性 T 细胞的帮助优于非特异性帮助
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200835
Joanna Fréderique de Graaf, Tamara Pesic, Felicia S. Spitzer, Koen Oosterhuis, M. Camps, Iris Zoutendijk, Bram Teunisse, Wahwah Zhu, Tsolere Arakelian, G. Zondag, Ramon Arens, Jeroen van Bergen, F. Ossendorp
{"title":"Neoantigen-specific T-cell help outperforms non-specific help in multi-antigen DNA vaccination against cancer","authors":"Joanna Fréderique de Graaf, Tamara Pesic, Felicia S. Spitzer, Koen Oosterhuis, M. Camps, Iris Zoutendijk, Bram Teunisse, Wahwah Zhu, Tsolere Arakelian, G. Zondag, Ramon Arens, Jeroen van Bergen, F. Ossendorp","doi":"10.1016/j.omton.2024.200835","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200835","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"14 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rejection resistant CD30.CAR-modified Epstein-Barr virus specific T cells as an off-the-shelf platform for CD30+ lymphoma 抗排斥 CD30.CAR 修饰的 Epstein-Barr 病毒特异性 T 细胞作为治疗 CD30+ 淋巴瘤的现成平台
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200814
David H. Quach, H. R. Ganesh, Y. D. Briones, N. Nouraee, Audrey Ma, Yezan F. Hadidi, C. Rooney
{"title":"Rejection resistant CD30.CAR-modified Epstein-Barr virus specific T cells as an off-the-shelf platform for CD30+ lymphoma","authors":"David H. Quach, H. R. Ganesh, Y. D. Briones, N. Nouraee, Audrey Ma, Yezan F. Hadidi, C. Rooney","doi":"10.1016/j.omton.2024.200814","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200814","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"227 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficiently targeting neuroblastoma (NB) by the combination of anti-ROR1 CAR NK cells and N-803 in-vitro and in-vivo of NB xenografts 抗ROR1 CAR NK细胞和N-803联合疗法在体外和体内对神经母细胞瘤（NB）异种移植物进行高效靶向治疗
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200820
Yaya Chu, Gaurav Nayyar, Meijuan Tian, D. Lee, Mehmet F. Ozkaynak, Jessica Ayala-Cuesta, Kayleigh Klose, Keira Foley, Alyssa S. Mendelowitz, Wen Luo, Yanling Liao, J. Ayello, Gregory Behbehani, Stanley R. Riddell, Tim Cripe, Mitchell S. Cairo
{"title":"Efficiently targeting neuroblastoma (NB) by the combination of anti-ROR1 CAR NK cells and N-803 in-vitro and in-vivo of NB xenografts","authors":"Yaya Chu, Gaurav Nayyar, Meijuan Tian, D. Lee, Mehmet F. Ozkaynak, Jessica Ayala-Cuesta, Kayleigh Klose, Keira Foley, Alyssa S. Mendelowitz, Wen Luo, Yanling Liao, J. Ayello, Gregory Behbehani, Stanley R. Riddell, Tim Cripe, Mitchell S. Cairo","doi":"10.1016/j.omton.2024.200820","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200820","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"13 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141142924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bispecific CAR-T cells targeting FAP and GPC3 have the potential to treat hepatocellular carcinoma 靶向 FAP 和 GPC3 的双特异性 CAR-T 细胞有望治疗肝细胞癌
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200817
Linfu Zhou, Yao Li, Diwei Zheng, Yongfang Zheng, Yuanbin Cui, Le Qin, Zhaoyang Tang, Dongdong Peng, Qiting Wu, Youguo Long, Yao Yao, N. Wong, James Y. Lau, Peng Li
{"title":"Bispecific CAR-T cells targeting FAP and GPC3 have the potential to treat hepatocellular carcinoma","authors":"Linfu Zhou, Yao Li, Diwei Zheng, Yongfang Zheng, Yuanbin Cui, Le Qin, Zhaoyang Tang, Dongdong Peng, Qiting Wu, Youguo Long, Yao Yao, N. Wong, James Y. Lau, Peng Li","doi":"10.1016/j.omton.2024.200817","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200817","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"110 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141133468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elucidating Prognostic Insights, Immune Infiltration and Therapeutic Response: Interplay of Cytoplasmic Poly(A) Tail Regulators in Hepatocellular Carcinoma 阐明预后洞察、免疫渗透和治疗反应：肝细胞癌中细胞质聚（A）尾调节因子的相互作用
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200816
Yi Liu, Yan Huang, Yunting Le, Yating Gao, Hui Wang, Jing Yang, Jialin Wang, Chaoxia Zou, Qiang Li
{"title":"Elucidating Prognostic Insights, Immune Infiltration and Therapeutic Response: Interplay of Cytoplasmic Poly(A) Tail Regulators in Hepatocellular Carcinoma","authors":"Yi Liu, Yan Huang, Yunting Le, Yating Gao, Hui Wang, Jing Yang, Jialin Wang, Chaoxia Zou, Qiang Li","doi":"10.1016/j.omton.2024.200816","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200816","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"340 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141144021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toll-like receptor 4 signaling activation domains promote CAR T cell function against solid tumors Toll 样受体 4 信号激活结构域促进 CAR T 细胞对抗实体瘤的功能
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200815
V. Mikolič, Jelica Pantović Žalig, Š. Malenšek, Matjaž Sever, D. Lainšček, Roman Jerala
{"title":"Toll-like receptor 4 signaling activation domains promote CAR T cell function against solid tumors","authors":"V. Mikolič, Jelica Pantović Žalig, Š. Malenšek, Matjaž Sever, D. Lainšček, Roman Jerala","doi":"10.1016/j.omton.2024.200815","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200815","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"27 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141056378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CDKN2A copy number alteration in bladder cancer: integrative analysis in patient-derived xenografts and cancer patients 膀胱癌中的 CDKN2A 拷贝数改变：患者衍生异种移植物和癌症患者的综合分析
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200818
Maria-Alexandra Papadimitriou, Katerina-Marina Pilala, Konstantina Panoutsopoulou, Panagiotis Levis, Georgios Kotronopoulos, Zoi Kanaki, Gedeon Loules, Maria Zamanakou, Dimitrios Linardoutsos, Diamantis C. Sideris, Konstantinos Stravodimos, Apostolos Klinakis, Andreas Scorilas, Margaritis Avgeris
{"title":"CDKN2A copy number alteration in bladder cancer: integrative analysis in patient-derived xenografts and cancer patients","authors":"Maria-Alexandra Papadimitriou, Katerina-Marina Pilala, Konstantina Panoutsopoulou, Panagiotis Levis, Georgios Kotronopoulos, Zoi Kanaki, Gedeon Loules, Maria Zamanakou, Dimitrios Linardoutsos, Diamantis C. Sideris, Konstantinos Stravodimos, Apostolos Klinakis, Andreas Scorilas, Margaritis Avgeris","doi":"10.1016/j.omton.2024.200818","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200818","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"322 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141138702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deletion of CD38 enhances CD19 chimeric antigen receptor T cell function 缺失 CD38 可增强 CD19 嵌合抗原受体 T 细胞的功能
Molecular Therapy: Oncology Pub Date : 2024-05-01 DOI: 10.1016/j.omton.2024.200819
Kimberly Veliz, Feng Shen, O. Shestova, M. Shestov, Alexander Shestov, Sara Sleiman, Tyler Hansen, Roddy S. O’Connor, Saar Gill
{"title":"Deletion of CD38 enhances CD19 chimeric antigen receptor T cell function","authors":"Kimberly Veliz, Feng Shen, O. Shestova, M. Shestov, Alexander Shestov, Sara Sleiman, Tyler Hansen, Roddy S. O’Connor, Saar Gill","doi":"10.1016/j.omton.2024.200819","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200819","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"16 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141135723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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