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Molecular Therapy: Oncology最新文献

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Smouldering Oncolysis by Foamy Virus Carrying CD19 as a CAR Target Escapes CAR T Detection by Genomic Modification 携带 CD19 作为 CAR 靶点的泡沫病毒产生的烟雾状肿瘤溶解可通过基因组修饰逃避 CAR T 检测
Molecular Therapy: Oncology Pub Date : 2024-07-01 DOI: 10.1016/j.omton.2024.200852
Jason M. Tonne, Karol M. Budzik, Talia Fernandez Carrasco, Landon E. Ebbert, Jill Thompson, R. Nace, Benjamin Kendall, Rosa M. Diaz, Stephen J. Russell, R. Vile
{"title":"Smouldering Oncolysis by Foamy Virus Carrying CD19 as a CAR Target Escapes CAR T Detection by Genomic Modification","authors":"Jason M. Tonne, Karol M. Budzik, Talia Fernandez Carrasco, Landon E. Ebbert, Jill Thompson, R. Nace, Benjamin Kendall, Rosa M. Diaz, Stephen J. Russell, R. Vile","doi":"10.1016/j.omton.2024.200852","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200852","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic changes of the immune microenvironment in the development of gastric cancer caused by inflammation 炎症导致胃癌发生过程中免疫微环境的动态变化
Molecular Therapy: Oncology Pub Date : 2024-07-01 DOI: 10.1016/j.omton.2024.200849
Siyuan Gan, Changfu Li, Rui Hou, Geng Tian, Yuan Zhao, Dan Ren, Wenjing Zhou, Fei Zhao, Kebo Lv, Jialiang Yang
{"title":"Dynamic changes of the immune microenvironment in the development of gastric cancer caused by inflammation","authors":"Siyuan Gan, Changfu Li, Rui Hou, Geng Tian, Yuan Zhao, Dan Ren, Wenjing Zhou, Fei Zhao, Kebo Lv, Jialiang Yang","doi":"10.1016/j.omton.2024.200849","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200849","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141838751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing TRAIL-based Therapy for Glioblastoma Through Combining the Constitutive TRAIL-Secreting Induced Neural Stem Cells with the Novel Small Molecule Anti-Cancer Drug TR-107 将TRAIL分泌诱导型神经干细胞与新型小分子抗癌药物TR-107相结合，加强基于TRAIL的胶质母细胞瘤疗法
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200834
Morrent Thang, Clara Mellows, Lauren E Kass, Sabrina C D Daglish, E. Fennell, Breanna Mann, Alison R. Mercer-Smith, Alain Valdivia, Lee M Graves, Shawn D. Hingtgen
{"title":"Enhancing TRAIL-based Therapy for Glioblastoma Through Combining the Constitutive TRAIL-Secreting Induced Neural Stem Cells with the Novel Small Molecule Anti-Cancer Drug TR-107","authors":"Morrent Thang, Clara Mellows, Lauren E Kass, Sabrina C D Daglish, E. Fennell, Breanna Mann, Alison R. Mercer-Smith, Alain Valdivia, Lee M Graves, Shawn D. Hingtgen","doi":"10.1016/j.omton.2024.200834","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200834","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"5 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141396116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regulation of CAR transgene expression to design semiautonomous CAR-T. 调控 CAR 转基因表达，设计半自主 CAR-T。
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200833
Paweł Głowacki, Cezary Tręda, Piotr Rieske
{"title":"Regulation of CAR transgene expression to design semiautonomous CAR-T.","authors":"Paweł Głowacki, Cezary Tręda, Piotr Rieske","doi":"10.1016/j.omton.2024.200833","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200833","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141402395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncolytic Vaccinia Virus Harboring CLEC2A Gene Enhances Viral Replication and Antitumor Efficacy 携带 CLEC2A 基因的肿瘤溶解性疫苗病毒可增强病毒复制和抗肿瘤功效
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200823
Chunqing Gao, Qi Ying, Yufeng Qiu, Ningbo Ren, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li
{"title":"Oncolytic Vaccinia Virus Harboring CLEC2A Gene Enhances Viral Replication and Antitumor Efficacy","authors":"Chunqing Gao, Qi Ying, Yufeng Qiu, Ningbo Ren, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li","doi":"10.1016/j.omton.2024.200823","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200823","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"117 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141408098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern 结直肠癌肝转移灶中 CIB1 的高表达与较差的生存率和组织病理学生长模式的替代相关
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200828
Shuang Fan, J. Fleischer, L. Dokshokova, Lena Sophie Böhme, Gwendolyn Haas, Alexandra Maria Schmitt, Fabio Bennet Gätje, Linde-Allegra Emmalie Rosen, H. Bohnenberger, Michael Ghadimi, Baolong Cui, Xingbo Xu, Joanna Maria Kalucka, Florian Bösch, Tiago De Oliveira, Lena-Christin Conradi
{"title":"High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern","authors":"Shuang Fan, J. Fleischer, L. Dokshokova, Lena Sophie Böhme, Gwendolyn Haas, Alexandra Maria Schmitt, Fabio Bennet Gätje, Linde-Allegra Emmalie Rosen, H. Bohnenberger, Michael Ghadimi, Baolong Cui, Xingbo Xu, Joanna Maria Kalucka, Florian Bösch, Tiago De Oliveira, Lena-Christin Conradi","doi":"10.1016/j.omton.2024.200828","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200828","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141391708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Breast Cancer Brain Metastases with Temozolomide is Enhanced in the Presence of an Oncolytic Virus Expressing an Anti-CD47 Antibody 表达抗-CD47抗体的肿瘤溶解病毒可增强替莫唑胺治疗乳腺癌脑转移瘤的效果
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200824
Jing Wang, L. Tian, Tasha Barr, Lewei Jin, Yuqing Chen, Zhiyao Li, Ge Wang, Jian-Chang Liu, Li-Shu Wang, Jianying Zhang, David Hsu, Mingye Feng, Michael A. Caligiuri, Jianhua Yu
{"title":"Treatment of Breast Cancer Brain Metastases with Temozolomide is Enhanced in the Presence of an Oncolytic Virus Expressing an Anti-CD47 Antibody","authors":"Jing Wang, L. Tian, Tasha Barr, Lewei Jin, Yuqing Chen, Zhiyao Li, Ge Wang, Jian-Chang Liu, Li-Shu Wang, Jianying Zhang, David Hsu, Mingye Feng, Michael A. Caligiuri, Jianhua Yu","doi":"10.1016/j.omton.2024.200824","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200824","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"629 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The supramolecular processing of liposomal Doxorubicin hinders its therapeutic efficacy in cells 脂质体多柔比星的超分子加工阻碍了其在细胞中的疗效
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200836
Annalisa Carretta, Aldo Moscardini, Giovanni Signore, D. Debellis, Federico Catalano, Roberto Marotta, Valentina Palmieri, Giulia Tedeschi, Lorenzo Scipioni, D. Pozzi, G. Caracciolo, Fabio Beltram, Francesco Cardarelli
{"title":"The supramolecular processing of liposomal Doxorubicin hinders its therapeutic efficacy in cells","authors":"Annalisa Carretta, Aldo Moscardini, Giovanni Signore, D. Debellis, Federico Catalano, Roberto Marotta, Valentina Palmieri, Giulia Tedeschi, Lorenzo Scipioni, D. Pozzi, G. Caracciolo, Fabio Beltram, Francesco Cardarelli","doi":"10.1016/j.omton.2024.200836","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200836","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"746 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transforming Pancreaticobiliary Cancer Treatment: Exploring the Frontiers of Adoptive Cell Therapy and Cancer Vaccines 变革胰胆管癌症治疗：探索适应性细胞疗法和癌症疫苗的前沿
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200825
N. Amhis, Julie Carignan, Lee-Hwa Tai
{"title":"Transforming Pancreaticobiliary Cancer Treatment: Exploring the Frontiers of Adoptive Cell Therapy and Cancer Vaccines","authors":"N. Amhis, Julie Carignan, Lee-Hwa Tai","doi":"10.1016/j.omton.2024.200825","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200825","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"10 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A general pHLA-CD80 scaffold fusion protein to promote efficient antigen-specific T-cell-based immunotherapy 促进高效抗原特异性 T 细胞免疫疗法的通用 pHLA-CD80 支架融合蛋白
Molecular Therapy: Oncology Pub Date : 2024-06-01 DOI: 10.1016/j.omton.2024.200827
Yue Wu, Xiao Liang, Yanping Sun, Jiangtao Ning, Yukun Dai, Shijie Jin, Yingchun Xu, Shuqing Chen, Liqiang Pan
{"title":"A general pHLA-CD80 scaffold fusion protein to promote efficient antigen-specific T-cell-based immunotherapy","authors":"Yue Wu, Xiao Liang, Yanping Sun, Jiangtao Ning, Yukun Dai, Shijie Jin, Yingchun Xu, Shuqing Chen, Liqiang Pan","doi":"10.1016/j.omton.2024.200827","DOIUrl":"https://doi.org/10.1016/j.omton.2024.200827","url":null,"abstract":"","PeriodicalId":516670,"journal":{"name":"Molecular Therapy: Oncology","volume":"712 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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