Archives of medical sciences. Atherosclerotic diseases最新文献

{"title":"The effect of eight-week resistance training on oxidative stress in isoproterenol-induced myocardial infarction in rats.","authors":"Ali Ojaghi, Morteza Jourkesh, Morteza Ojaghi, Lamia Mirheidar, Abolfazl Neshati","doi":"10.5114/amsad/188093","DOIUrl":"10.5114/amsad/188093","url":null,"abstract":"<p><strong>Introduction: </strong>Although reliable new evidence has identified several advantages of resistance training (ResEx) on cardiac performance, the role of this type of training in protecting the myocardium against ischemia-reperfusion (IR) injury is not clear. The aim of this study was to investigate the effect of resistance training on cardioprotection versus IR-induced injury.</p><p><strong>Material and methods: </strong>60-day-old male Wistar rats (<i>n</i> = 24), weighing 220-240 g, were divided into four groups: Resistance Training (ResEx), Isoproterenol (ISO), Resistance Training + Isoproterenol (ResEx + ISO), and control groups (<i>n</i> = 6 for each). Trained rats performed exercise in a squat-training apparatus (8-12 repetitions/set, eight sets/day, and 5 days/week for 8 weeks). After the last training session, all the rats were sacrificed with ketamine xylazine injection. The heart of rats was removed from the body and washed quickly with cold PBS, immediately put in liquid nitrogen, and stored at -70°C. Superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) activity was measured.</p><p><strong>Results: </strong>Induction of ischemia decreased SOD and CAT activity but had no effect on the activity of GPX. Eight weeks of resistance training significantly increased activity of SOD and CAT compared to the ISO group.</p><p><strong>Conclusions: </strong>The results of the present research demonstrated that ischemia induced by isoproterenol injection during 8 weeks of resistance training did not lead to a decrease in SOD activity and prevented the reduction of CAT activity.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e177-e182"},"PeriodicalIF":0.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the link between kidney dimensions and anthropometric measurements: insights from a Saudi population study.","authors":"Mansour Almanaa, Haitham Alahmad, Mohammad Alarifi, Khaled Alenazi, Ahmad Abanomy, Khalid Alneghaimishi, Bashayr Alshamrani, Raed Albathi","doi":"10.5114/amsad/192995","DOIUrl":"10.5114/amsad/192995","url":null,"abstract":"<p><strong>Introduction: </strong>Ultrasound (US) measurements of kidney dimensions are essential for correlating with height, weight, and body mass index (BMI), establishing kidney size baselines, and assessing renal health. The global rise in obesity has increased interest in the links between BMI and chronic kidney disease (CKD). This study investigates the relationship between renal dimensions (length, width, and thickness) and anthropometric measures (height, weight, and BMI) in a Saudi population.</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted at two ultrasound clinics in Riyadh, Saudi Arabia, with 129 participants (73 males and 56 females) aged 18-60 years. Kidney dimensions were measured using ultrasound machines. Spearman correlation assessed relationships between kidney dimensions and age, height, weight, and BMI, while the Mann-Whitney U test investigated sex differences.</p><p><strong>Results: </strong>Significant correlations were identified between kidney dimensions and anthropometric measures. Age negatively correlated with kidney thickness for both kidneys (right: <i>r</i> = -0.502, <i>p</i> < 0.0001; left: <i>r</i> = -0.542, <i>p</i> < 0.0001) and left kidney width (<i>r</i> = -0.204, <i>p</i> = 0.020). Height positively correlated with all kidney dimensions. Weight also positively correlated with kidney dimensions. BMI showed positive correlations with right kidney length (<i>r</i> = 0.219, <i>p</i> = 0.013) and width (<i>r</i> = 0.319, <i>p</i> < 0.0001), and left kidney length (<i>r</i> = 0.209, <i>p</i> = 0.018). Males had greater kidney thickness and left kidney width compared to females.</p><p><strong>Conclusions: </strong>This study establishes significant correlations between renal dimensions and anthropometric measures in a Saudi population, highlighting the importance of considering individual characteristics in renal assessments. These findings support the development of personalized clinical guidelines for improved renal condition management.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e171-e176"},"PeriodicalIF":0.0,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multisystem inflammatory syndrome in adults hospitalizations in the United States; evaluating patient characteristics, COVID-19 associations, and mortality.","authors":"Nomesh Kumar, Noem N Syed, Rahul Singla, Fnu Bawna, Mushood Ahmed, Hritvik Jain, Jasninder S Dhaliwal, Gagandeep S Arora, Renuka Verma, Kamleshun Ramphul, Raheel Ahmed, Sajeel Ahmed","doi":"10.5114/amsad/192994","DOIUrl":"10.5114/amsad/192994","url":null,"abstract":"<p><strong>Introduction: </strong>Multisystem inflammatory syndrome in adults (MIS-A) is thought to be closely linked with COVID-19 infection. This study aims to elucidate the demographics and clinical characteristics of MIS-A, aiding in timely diagnosis and management.</p><p><strong>Methods: </strong>Utilizing the National Inpatient Sample (NIS) database (2021), patients were stratified into MIS-A and non-MIS-A groups. Baseline characteristics and comorbidities, the association with COVID-19, post-COVID-19 syndrome, and personal history of COVID-19, as well as impact on mortality were studied.</p><p><strong>Results: </strong>We identified 2,730 adults with MIS-A. MIS-A was linked with active COVID-19 infection (aOR = 27.436, <i>p</i> < 0.001), post-COVID-19 syndrome (aOR = 32.766, <i>p</i> < 0.001), personal history of COVID-19 (aOR = 2.963, <i>p</i> < 0.001), and an increased mortality (aOR = 3.743, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Using data adjusted for confounding variables, MIS-A was found to be associated with active and past COVID-19, and a greater mortality rate when compared to non-MIS-A patients.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e165-e170"},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late post-EVAR abdominal aortic aneurysm rupture: a meta-analysis study.","authors":"Spyros Papadoulas, Christos Pitros, Andreas Tsimpoukis, Chrysanthi Papageorgopoulou, Sofia Prentza, Vasileios Leivaditis, Andreas Antzoulas, Francesk Mulita, Konstantinos G Moulakakis","doi":"10.5114/amsad/190421","DOIUrl":"10.5114/amsad/190421","url":null,"abstract":"<p><p>This study presents updated information on post-endovascular aneurysm repair (EVAR) late aortic rupture (LAR) as the data in the literature are limited. It comprises a meta-analysis based on the recent evidence regarding the incidence, causes, treatment outcomes, and prognosis of post-EVAR. A meta-analysis was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Studies were identified by searching electronic databases and scanning bibliographic references from 1991 to April 1, 2023. Our analysis provided evidence that the most common causes of rupture after EVAR were type Ia and Ib Endoleaks (Els). Post-rupture mortality after EVAR was high (35.6%) and comparable to the morbidity of <i>de novo</i> ruptures. Endovascular repair appears to have better results compared to conversion to open repair. A significant number of patients had prior endovascular reoperations and inadequate follow-up. Patient compliance with the surveillance protocol is mandatory.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e152-e164"},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes management in the era of artificial intelligence.","authors":"Athanasia K Papazafiropoulou","doi":"10.5114/amsad/183420","DOIUrl":"10.5114/amsad/183420","url":null,"abstract":"<p><p>Artificial intelligence is growing quickly, and its application in the global diabetes pandemic has the potential to completely change the way this chronic illness is identified and treated. Machine learning methods have been used to construct algorithms supporting predictive models for the risk of getting diabetes or its complications. Social media and Internet forums also increase patient participation in diabetes care. Diabetes resource usage optimisation has benefited from technological improvements. As a lifestyle therapy intervention, digital therapies have made a name for themselves in the treatment of diabetes. Artificial intelligence will cause a paradigm shift in diabetes care, moving away from current methods and toward the creation of focused, data-driven precision treatment.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e122-e128"},"PeriodicalIF":0.0,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of acute kidney injury among octogenarians undergoing open mitral valve repair.","authors":"Shoaib Ali, Kamleshun Ramphul, Asad Rahman, Sudhamai Akkaramani, Jasninder Dhaliwal, Iosif Karalis, Maria Vakali, Nabeel Ahmed, Haania Shahbaz, Mushood Ahmed, Sarah Mackenzie Picker, Sukhmeet Dhillon, Adeel Ahmad, Hemamalini Sakthivel, Farhan Shahid, Javed Ahmed, Raheel Ahmed","doi":"10.5114/amsad/189732","DOIUrl":"10.5114/amsad/189732","url":null,"abstract":"","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e129-e132"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pericarditis in a patient nine months after transcatheter aortic valve replacement: a case report and brief review of literature.","authors":"Gagandeep Singh Arora, James Elkins, Harnoor Singh","doi":"10.5114/amsad/189734","DOIUrl":"10.5114/amsad/189734","url":null,"abstract":"","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e133-e136"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking the cannabis paradox: in-hospital outcomes of cannabis users admitted with acute myocardial infarction over a 20-year period in the United States.","authors":"Nomesh Kumar, Nitish Kumar Behary Paray, Kamleshun Ramphul, Renuka Verma, Jasninder Singh Dhaliwal, Camryn Schroeder, Lily Liu, Fnu Bawna, Hemamalini Sakthivel, Raheel Ahmed","doi":"10.5114/amsad/189731","DOIUrl":"10.5114/amsad/189731","url":null,"abstract":"<p><strong>Introduction: </strong>Cannabis is increasingly becoming a socially acceptable substance, with multiple countries having legalised its consumption. Epidemiological studies have demonstrated an association between cannabis use and an increased risk of developing coronary artery disease. However, there is a lack of studies about the influence of cannabis consumption on the outcomes following acute myocardial infarction (AMI).</p><p><strong>Material and methods: </strong>We retrospectively analysed hospitalised patients with a primary diagnosis of AMI from the 2001 to 2020 National Inpatient Sample (NIS). Pearson's χ² tests were applied to categorical variables, and <i>t</i>-tests for continuous variables. We conducted a 1:1 propensity score matching (PSM). Multivariate regression models were deployed on the PSM sample to estimate the differences in several events and all-cause mortality.</p><p><strong>Results: </strong>A total of 9,930,007 AMI patients were studied, of whom 117,641 (1.2%) reported cannabis use. Cannabis users had lower odds of atrial fibrillation (aOR = 0.902, <i>p</i> < 0.01), ventricular fibrillation (aOR = 0.919, <i>p</i> < 0.01), cardiogenic shock (aOR = 0.730, <i>p</i> < 0.01), acute ischaemic stroke (aOR = 0.825, <i>p</i> < 0.01), cardiac arrest (aOR = 0.936, <i>p</i> = 0.010), undergoing PCI (aOR = 0.826, <i>p</i> < 0.01), using IABP (aOR = 0.835, <i>p</i> < 0.01), and all-cause mortality (aOR = 0.640, <i>p</i> < 0.01), but with higher odds of supraventricular tachycardia (aOR = 1.104, <i>p</i> < 0.01), ventricular tachycardia (aOR = 1.054, <i>p</i> < 0.01), CABG use (aOR = 1.040, <i>p</i> = 0.010), and acute kidney injury (aOR = 1.103, <i>p</i> < 0.01).</p><p><strong>Conclusions: </strong>Among patients aged 18-80 years admitted to hospital with AMI between 2001 and 2020 in the United States, cannabis use was associated with lower risks of cardiogenic shock, acute ischaemic stroke, cardiac arrest, PCI use, and in-hospital mortality.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e137-e146"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical insights into the diagnosis and management of post-myocardial infarction left ventricular aneurysm of the inferior wall: a case report and brief review.","authors":"Gagandeep Singh Arora, Tanveen Kaur Gill","doi":"10.5114/amsad/189733","DOIUrl":"10.5114/amsad/189733","url":null,"abstract":"","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e147-e151"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of the development of isolated heart perfusion experimental model and its pioneering role in understanding heart physiology.","authors":"Vasileios Leivaditis, Francesk Mulita, Manfred Dahm, Konstantinos Grapatsas, Athanasios Papatriantafyllou, Eleni Bekou, Georgios-Ioannis Verras, Konstantinos Tasios, Levan Tchabashvili, Konstantinos Markakis, Vasileios Lozos, Efstratios Koletsis","doi":"10.5114/amsad/188270","DOIUrl":"10.5114/amsad/188270","url":null,"abstract":"<p><p>The isolated heart perfusion model, a fundamental tool in cardiovascular research, has evolved significantly since its inception in the late 19^th century. This review traces the development of the isolated heart model, from its early adaptations by pioneers such as Langendorff and Starling to modern advancements by researchers like Morgan and Neely. We discuss the various applications of the model in pharmacological testing, disease modeling, and educational settings, emphasizing its crucial role in understanding cardiac function and disease mechanisms. Recent technological enhancements, including high-resolution imaging, integration with bioengineering, and advanced genomic and proteomic analyses, have significantly broadened the capabilities of these models. Looking forward, we explore potential future developments such as the integration of precision medicine, stem cell research, and artificial intelligence, which promise to revolutionize the use of isolated heart perfusion models. This review highlights the model's crucial role in bridging experimental research and clinical applications.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e109-e121"},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}