Archives of medical sciences. Atherosclerotic diseases最新文献

{"title":"Navigating the intricacies of arterial and venous cement embolism in spinal surgery: two case reports illuminating divergent pathways and management strategies.","authors":"Vasileios Leivaditis, Athanasios Papatriantafyllou, Manfred Dahm, Bendeguz Istvan Nagy, Tamas Büki, Ioanna Akrida, Francesk Mulita, Konstantinos Tasios, Levan Tchabashvili, Konstantinos Grapatsas, Spyros Papadoulas, Konstantinos Markakis, Efstratios Koletsis","doi":"10.5114/amsad/188271","DOIUrl":"10.5114/amsad/188271","url":null,"abstract":"","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e102-e108"},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxygen venous saturation is associated with subclinical myocardial systolic dysfunction in patients with end-stage renal disease undergoing hemodialysis.","authors":"Spyridon Maragkoudakis, Ioannis Tzanakis, Maria Mamaloukaki, Nikolaos Damianakis, Emmanuel Michelakis, Maria Marketou, Eftychios Vittorakis, Emmanouel Sideras, Vasiliki Katsi, Georgios Kochiadakis","doi":"10.5114/amsad/188091","DOIUrl":"10.5114/amsad/188091","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this prospective study was to evaluate the impact of hemodialysis (HD) on myocardial injury, of both right and left ventricle function as well as their association with venous oxygen saturation (ScvO2) alterations.</p><p><strong>Material and methods: </strong>We included in the study stable consecutive patients with end-stage renal disease (ESRD) undergoing regular HD. Right and left ventricular speckle-tracking echocardiographies were performed in all patients. The examination calculates the global systolic longitudinal strain (GLS). Blood samples were obtained from the central vein in order to measure the O2 saturation (ScvO2) levels prior and post HD. High sensitive troponin (HST) was also measured in all patients before and after HD.</p><p><strong>Results: </strong>Thirty seven patients were evaluated. We found that both mean ScvO2 and left ventricle GLS (LV GLS) were deteriorated after the dialysis session: 76.47 ±1.98 to 71.54 ±5.10, <i>p <</i> 0.05 and -17.73 ±3.44 to -14.21 ±3.44%, <i>p</i> < 0.01, respectively. HST levels were increased at the end of hemodialysis, 22.45 ±13.26 to 106.78 ±146.19 pg/ml, <i>p</i> < 0.01. A significant correlation was also found between the decrease of LV GLS with the ScvO2 reduction, <i>p</i> = 0.001<i>,</i> as well as with the increase of the HST levels, <i>p =</i> 0.001.</p><p><strong>Conclusions: </strong>Our data demonstrate that there is a significant worsening of the GLS of the left ventricle at the end of the dialysis, which is strongly associated with the concomitant deterioration of ScvO2. The may be a reliable index of circulatory stress indicating a subclinical myocardial dysfunction during HD.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e94-e101"},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic and clinical characteristics of patients with varicose veins in Albania: a retrospective, single-centre analysis.","authors":"Francesk Mulita, Platon Dimopoulos, Georgios-Ioannis Verras, Petraq Mustaqe, Jerina Jaho, Vasileios Leivaditis, Levan Tchabashvili, Konstantinos Tasios, Andreas Antzoulas, Christos Pitros, Spyros Papadoulas, Paraskevi F Katsakiori","doi":"10.5114/amsad/183653","DOIUrl":"10.5114/amsad/183653","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic venous disease (CVD) constitutes a frequently underdiagnosed pathological condition that progressively diminishes patients' quality of life and imposes an escalating strain on healthcare resources. This study aims to comprehensively investigate the epidemiological landscape of varicose vein disease, examining age group distributions, gender patterns, residence influences, marital status correlations, weight considerations, educational impacts, and various aspects related to varicose veins.</p><p><strong>Material and methods: </strong>This was a single-centre retrospective analysis, in Albania from May 2018 to September 2023. Data were collected retrospectively through hospital records. Data collection involved administering a structured questionnaire to study participants, categorically organised into three sections. The first section focused on collecting demographic information, the second section involved self-perception of identifying risk factors associated with varicose veins, and the final section included inquiries about the history of variceal surgery.</p><p><strong>Results: </strong>The CEAP classification distribution in our cohort revealed a predominant presence of C2 (varicose veins) in 53.3% of patients, followed by C3 (oedema) at 29.2%, and C4 (changes in skin and subcutaneous tissue secondary to CVD) at 10.5%, whereas C5 (healed venous ulcer) and C6 (active venous ulcer) were less frequent. Based on the body mass index (BMI) scale, data from patients indicated that 9.7% were in the category of underweight, 54.8% had a normal BMI, and 35.5% were categorised as overweight.</p><p><strong>Conclusions: </strong>The study's thorough exploration of patient perspectives, risk factors, and treatment choices contributes to a holistic understanding of varicose vein management, emphasising the importance of personalised approaches that account for demographic variations and individual beliefs.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e41-e46"},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Randomized clinical trial evaluating the efficacy of synbiotic supplementation on serum endotoxin and trimethylamine N-oxide levels in patients with dyslipidaemia.","authors":"Shekoufeh Salamat, Alireza Jahan-Mihan, Mohammad Reza Tabandeh, Anahita Mansoori","doi":"10.5114/amsad/178106","DOIUrl":"10.5114/amsad/178106","url":null,"abstract":"<p><strong>Introduction: </strong>Elevated serum endotoxin and trimethylamine N-oxide (TMAO) are associated with metabolic disorders including dyslipidaemia and insulin resistance. This study aimed to evaluate the impact of a 12-week treatment with a synbiotic supplement on serum endotoxin and TMAO levels in patients diagnosed with dyslipidaemia.</p><p><strong>Material and methods: </strong>A total of 56 patients who met the study inclusion criteria were recruited in this randomized, double-blind clinical trial. Participants were randomly assigned into intervention and control groups and received either synbiotic or placebo sachets twice a day for 12 weeks. The sociodemographic data, food intake, physical activity, and anthropometric indices of participants were assessed before and after intervention. Serum endotoxin, TMAO, and fasting blood glucose (FBG) levels were measured at the baseline and end of the study.</p><p><strong>Results: </strong>No significant difference in the baseline characteristics of participants in the 2 groups was observed. After the 12 weeks of intervention, the mean of serum endotoxin (<i>p</i> < 0.0001), TMAO (<i>p</i> < 0.0001), and FBG (<i>p</i> < 0.0001) was decreased in patients who received synbiotic supplements while no significant change was observed in the control group. Moreover, a significant positive correlation between changes in endotoxin (<i>r</i> = 0.41, <i>p</i> = 0.041) and TMAO (<i>r</i> = 0.40, <i>p</i> = 0.047) with FBG changes was observed.</p><p><strong>Conclusions: </strong>A significant reduction in serum endotoxin and TMAO levels, as well as improvements in FBG, following 12 weeks of supplementation with synbiotics, may offer a potential approach for improving metabolic status in patients with dyslipidaemia.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e18-e25"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10905263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of pitavastatin treatment on PON1 lactonase activity in patients with hypercholesterolaemia.","authors":"Kazuhiko Kotani, Naoki Sakane, Alejandro Gugliucci","doi":"10.5114/amsad/178105","DOIUrl":"10.5114/amsad/178105","url":null,"abstract":"","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"9 ","pages":"e16-e17"},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10905260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global prevalence of cardiovascular diseases by gender and age during 2010-2019.","authors":"Irene Rethemiotaki","doi":"10.5114/amsad/176654","DOIUrl":"10.5114/amsad/176654","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to evaluate the global, gender, and age-related cardiovascular disease (CVD) burden during 2010-2019. Not only the global trend in the prevalence of CVDs was studied but also whether there was a statistically significant difference between genders and ages during 2010-2019.</p><p><strong>Material and methods: </strong>Detailed information from 2010 to 2019, including global rates of prevalence of 11 categories of CVD, was collected from the Global Burden of Disease Study 2019. The statistical methods used to analyze the results of this study are the independent samples <i>t</i>-test and one-way analysis of variance (ANOVA) test.</p><p><strong>Results: </strong>The global prevalence rate of CVDs increased from 0.061% in 2010 to 0.070% in 2019. There was a statistically significant difference in prevalence rates between genders in all cardiovascular diseases except atrial fibrillation and flutter. Females have higher prevalence rates of CVDs worldwide. Moreover, females have statistically significantly higher prevalence rates of stroke, hypertensive heart disease, rheumatic heart disease, non-rheumatic valvular heart disease, endocarditis, peripheral artery disease and other cardiovascular and circulatory diseases globally. On the other hand, males have statistically significantly higher prevalence rates of cardiomyopathy and myocarditis, and ischemic heart disease globally. Rheumatic heart disease has a statistically significantly higher prevalence rate in the age group of 25-49 years than the other age groups.</p><p><strong>Conclusions: </strong>The significance of this study is not only that it has succeeded in evaluating the global, gender, and age-related cardiovascular disease (CVD) burden, finding statistically significant associations, but it is also the only study to achieve this goal in the last decade.</p>","PeriodicalId":516556,"journal":{"name":"Archives of medical sciences. Atherosclerotic diseases","volume":"8 ","pages":"e196-e205"},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10811545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139572460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}