İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi最新文献

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Müzik Terapinin Şizofreni Tanılı Bireylerde Günlük Yaşam Aktivitelerine Katılımlarına ve Yaşam Kalitelerine Etkisinin İncelenmesi 音乐疗法对精神分裂症患者参与日常活动和生活质量的影响调查
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1307721
Hülya Yaman, Başar Öztürk
{"title":"Müzik Terapinin Şizofreni Tanılı Bireylerde Günlük Yaşam Aktivitelerine Katılımlarına ve Yaşam Kalitelerine Etkisinin İncelenmesi","authors":"Hülya Yaman, Başar Öztürk","doi":"10.38079/igusabder.1307721","DOIUrl":"https://doi.org/10.38079/igusabder.1307721","url":null,"abstract":"Aim: This study was created to increase the scope of music therapy for daily life, quality of life and functionality of individuals with schizophrenia. \u0000Method: The study included 25 individuals between the ages of 25-75 who were diagnosed with schizophrenia, and living in a disability-free living center in the province of Istanbul. Selected individuals listened to Bûselik maqam music, which was recorded in advance, for 30 minutes, in a total of 6 sessions once a week in the morning, in the special area reserved for music therapy. Sociodemographic information form, KATZ Activities of Daily Living Scale, Life Satisfaction Questionnaire, Lawton and Brody's Auxiliary Activities of Daily Living Scale, Brief Selectivity Assessment Scale, and Brief Psychiatric Rating Scale are used in the study. Wilcoxon Signed Ranks analysis was used for intragroup comparisons. \u0000Results: As a result of the study, no significant difference was detected in the intervals in daily living activities, quality of life and functionality of music therapy before and after the intervention (p>0.05).\u0000Conclusion: Regarding this study, receptive music therapy alone is not effective in individuals with schizophrenia. We think that leisure activity training under the leadership of occupational therapists during receptive music therapy will produce healthy results. In this way, we foresee that the intervention programs prepared by occupational therapists in a person-centered manner will increase the social functionality and range of patients and lead to positive results in society.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"70 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Otizmli Çocuklarda Glutensiz Kazeinsiz Diyet: Oftalmik ve Davranışsal Belirtilerin Klinik Sonuçları 自闭症儿童的无麸质酪蛋白饮食:眼科和行为症状的临床结果
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1378810
Öznur Özge Özcan, İ. Şahbaz, Emre Taşdöndüren, M. Karahan
{"title":"Otizmli Çocuklarda Glutensiz Kazeinsiz Diyet: Oftalmik ve Davranışsal Belirtilerin Klinik Sonuçları","authors":"Öznur Özge Özcan, İ. Şahbaz, Emre Taşdöndüren, M. Karahan","doi":"10.38079/igusabder.1378810","DOIUrl":"https://doi.org/10.38079/igusabder.1378810","url":null,"abstract":"Aim: To evaluate the ophthalmic and behavioral effects of a gluten-free casein-free diet (GCFD) in autism spectrum disorder (ASD).\u0000Method: The study was conducted from November 2020 to January 2023. We designed an 8-week clinical trial of GCFD on corneal reflex, pupil size, body mass index (BMI), weight, Autistic Disorder Index, Communication, Social interaction, and Stereotype Behavior. \u0000Results: A total of thirty participants completed the trial. GCFD reduced BMI [%95 CI -4.8895 to -2.1305 (P < 0.0001)], weight [%95 CI -8.5153 to -0.0647 (P = 0.0467)], Autistic Disorder Index [%95 CI -28.0359 to -16.2841 (P < 0.0001)], Communication [%95 CI -3.3325 to -1.6675 (P < 0.0001)], Social Interaction [%95 CI -4.3190 to -2.4010 (P < 0.0001)], and Stereotype Behavior [%95 CI -2.3939 to -0.2461 (P =0.01)] significantly. GCFD also reduced left [%95 CI -2.2421 to -1.6779 (P <0.0001)] and right pupil size [%95 CI -2.2999 to -1.7201 (P <0.0001)] significantly. Conversely, corneal reflex was significantly increased [95% CI 0.2159 to 2.1241 (P = 0.01)]. No differences were observed for IPD.\u0000Conclusion: This study suggested that the GCFD can effectively control ASD behaviors as well as regulate autonomic functions related to ophthalmic markers such as pupil size and corneal reflex, but more research is needed.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"62 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kanser Türlerinde Diyet Posası Alımının Etkisi Nedir? 膳食果肉摄入量对癌症类型有何影响?
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.980978
Fatma Bengü KUYULU BOZDOĞAN, Aybala Tazeoğlu
{"title":"Kanser Türlerinde Diyet Posası Alımının Etkisi Nedir?","authors":"Fatma Bengü KUYULU BOZDOĞAN, Aybala Tazeoğlu","doi":"10.38079/igusabder.980978","DOIUrl":"https://doi.org/10.38079/igusabder.980978","url":null,"abstract":"Diyet lifleri kardiyovasküler hastalık, diabetes mellitus, obezite ve kanser gibi yaşamı tehdit eden kronik hastalıkların kontrolünde yararlı etkilerinden dolayı insan sağlığında potansiyel formülasyonlar olarak bilinir. Son yıllarda dünyanın dört bir yanındaki bilim insanları diyetle lif alımı ile kanser arasındaki etkileşimi değerlendirmek için büyük ilgi gösterdiler. Mevcut incelemenin ana odak noktası diyetle lif alımının önemini açıkça vurgulamaktır. Şimdi, beslenme ile lif alımının gelecek vaat eden sağlık yararlarını kanıtlamak için yeni formülasyonlar geliştirilmesi hedeflenmektedir.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"45 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nöropatolojide İntraoperatif Konsültasyonda Tanısal Yaklaşımın Kurumsal Deneyimi 神经病理学术中会诊诊断方法的机构经验
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1379432
Zuhal KUŞ SİLAV
{"title":"Nöropatolojide İntraoperatif Konsültasyonda Tanısal Yaklaşımın Kurumsal Deneyimi","authors":"Zuhal KUŞ SİLAV","doi":"10.38079/igusabder.1379432","DOIUrl":"https://doi.org/10.38079/igusabder.1379432","url":null,"abstract":"Amaç: Nöropatolojide intraoperatif konsültasyonda kullanılan squash/smear sitolojisinin donma artefaktlarının önlenmesi, doku korunması, hızlı sonuç alınması ve dondurulmuş kesitlere göre düşük maliyet gibi avantajları vardır. Bu çalışmada smear ve frozen tekniklerinin tanısal doğruluk, etkinlik, avantaj ve dezavantajları açısından karşılaştırılması amaçlandı.\u0000Yöntem: Doksan iki neoplastik ve 16 non-neoplastik olmak üzere toplam 108 merkezi sinir sistemi olgusu frozen kesit (n=101) ve yayma (n=104) teknikleri kullanılarak incelendi. Frozen ve smear bulguları arasındaki farklar Fisher's Exact Test ile değerlendirildi, sensitivite ve spesifisite %95 güven aralığında belirlendi. \u0000Bulgular: Smear ve frozen kesitlerin tanısal doğruluk oranları sırasıyla %80 ve %85,7; sensitiviteleri %86 ve %93; ve spesifiteleri %70 ve %72,7 idi. Frozen tekniği ile elde edilen daha yüksek oranlar istatistiksel olarak anlamlı bulunmadı (P>0.05). Primer merkezi sinir sistemi tümörlerinde spesifik tanı oranları smear için %58, frozen teknik için %50,7 idi ve her ikisinin birlikte kullanılması tanısal doğruluk, sensitivite ve spesifisite oranlarını arttırdı.\u0000Sonuç: Frozen ve smear yöntemlerinin tanısal doğruluk oranlarının benzerliği, nöroşirürji IOT uygulamalarında sitolojinin tek başına kullanılabileceğini düşündürmektedir.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"31 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is Ultrasound-Guided Percutaneous Nephrostomy Efficacious and Safe in Pregnant Patients?: A Single Center Experience 超声引导下的经皮肾造瘘术对妊娠患者有效且安全吗?单中心经验
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1366562
I. Mutlu, A. Dablan, Mehmet Cingöz, Tuğçe Arslanoğlu, Ö. Kılıçkesmez
{"title":"Is Ultrasound-Guided Percutaneous Nephrostomy Efficacious and Safe in Pregnant Patients?: A Single Center Experience","authors":"I. Mutlu, A. Dablan, Mehmet Cingöz, Tuğçe Arslanoğlu, Ö. Kılıçkesmez","doi":"10.38079/igusabder.1366562","DOIUrl":"https://doi.org/10.38079/igusabder.1366562","url":null,"abstract":"Aim: To evaluate the safety and efficacy of ultrasound-guided percutaneous nephrostomy (PCN) placement in pregnancy.\u0000Method: Medical records of 26 pregnant patients who were inserted with a total of 27 PCN catheters between June 2020 to June 2023 were retrospectively analyzed to assess imaging findings, procedural parameters, technical success, delivery outcomes, and procedural complications.\u0000Results: At the time of placement of the PCN, the mean gestational age was 29.04±7.01 weeks (range 7 - 36 weeks). The indications for insertion of the PCN catheter included: 1) obstructing calculi (46.2%), 2) pyelonephritis (34.6%), and 3) symptomatic hydronephrosis without calculi (19.2%). Successful catheter placement was achieved in 25/27 procedures, yielding a success rate of 92.59%, and no major complications. Minor instances of transient hematuria were encountered in three cases. The mean duration of catheter retention was 72.58 days. All patients exhibited significant clinical and symptomatic improvement. Among these patients, 22 patients (84.6%) delivered their babies at full-term, 3 patients (11.5%) delivered prematurely, and 1 patient (3.8%) experienced a miscarriage.\u0000Conclusion: Ultrasound-guided PCN placement is a reliable method with high success and efficacy that can be applied during pregnancy. This procedure avoids the use of ionizing radiation, ensuring safety for both the fetus and the mother.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"72 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of University Students' Attitudes Towards Individuals Living with HIV/AIDS 评估大学生对艾滋病毒/艾滋病感染者的态度
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1385401
Nese Kiskac
{"title":"Evaluation of University Students' Attitudes Towards Individuals Living with HIV/AIDS","authors":"Nese Kiskac","doi":"10.38079/igusabder.1385401","DOIUrl":"https://doi.org/10.38079/igusabder.1385401","url":null,"abstract":"Aim: The purpose of this study was to ascertain how college students felt about people who were HIV/AIDS positive.\u0000Method: The study is cross-sectional and descriptive in nature. The data of the study were collected from 367 university students through an online questionnaire. The Attitudes Towards Individuals Living with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) Scale for University Students and the participants' personal data identification form were utilized as data collection instruments. The statistical program IBM SPSS 26.0 was utilized to analyze the data.\u0000Results: It was discovered that the participants' mean age was 21.60±2.50, with 77.1% of them being female and 39.2% belonging to the senior category. The middle level scale had a mean overall score of 58.28±11.72. Gender and the overall Attitudes Toward Individuals Living with HIV/AIDS Scale score showed a significant correlation (p<0.05). It was discovered that women exhibited more empathy and had more favorable views toward those who were HIV/AIDS positive. Grade level and the sub-dimensions of acceptance, relationship, and empathy on the Attitudes Towards Individuals Living with HIV/AIDS Scale were found to be significantly correlated (p<0.05) when the association between the two variables was evaluated.\u0000Conclusion: In conclusion, sexually transmitted illnesses should be taught to university students who fall into the high-risk category for HIV/AIDS. Higher knowledge level university students will also have positive attitudes toward those living with HIV/AIDS. Nurses have a great role in informing and educating these individuals. Nurses should make interventions especially for adolescents with the role of educator and counselor. In addition, courses on infectious diseases and sexually transmitted diseases should be included in the curriculum of university students.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"66 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sağlıklı Kadınlarda Reformer Pilates Egzersizlerinin Psikososyal Parametrelere Etkisi 变形器普拉提运动对健康女性社会心理参数的影响
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1325947
Hümeyra Ki̇loatar, Nisa Türütgen, M. B. Karavelioğlu
{"title":"Sağlıklı Kadınlarda Reformer Pilates Egzersizlerinin Psikososyal Parametrelere Etkisi","authors":"Hümeyra Ki̇loatar, Nisa Türütgen, M. B. Karavelioğlu","doi":"10.38079/igusabder.1325947","DOIUrl":"https://doi.org/10.38079/igusabder.1325947","url":null,"abstract":"Amaç: Bu çalışmanın amacı, reformer pilates egzersizlerinin sağlıklı kadınlarda benlik saygısı, kaygı düzeyi, egzersiz algısı ve yaşam kalitesi üzerindeki etkisini incelemektir.\u0000Yöntem: Otuz yedi sağlıklı kadın (ortalama yaş=21,08±1,09 yıl) iki gruba ayrıldı: müdahale grubu (n=17) ve kontrol grubu (n=19). Müdahale grubu haftada 3 gün olmak üzere 8 hafta boyunca 24 seans reformer pilates programını tamamlarken, kontrol grubu herhangi bir egzersiz programına katılmadı. Tüm değerlendirmeler çalışmanın başında ve 8 haftanın sonunda Rosenberg Benlik Saygısı Ölçeği, Durumluk ve Sürekli Kaygı Ölçeği, Egzersiz Faydaları-Engelleri Ölçeği ve WHOQOL-BREF kullanılarak yapıldı.\u0000Bulgular: Müdahale döneminin sonunda, durumluk anksiyete düzeyi kontrol grubunda istatistiksel olarak anlamlı şekilde azaldı (p<0,05). Egzersiz Faydaları-Engelleri Ölçeği-Yarar skoru yalnızca deney grubunda anlamlı olarak azaldı (p<0,05). Psikososyal parametrelerdeki değişimler açısından müdahale ve kontrol grupları arasında anlamlı bir farklılık gözlemlenmedi (p>0,05).\u0000Sonuç: Reformer pilates egzersizleri sağlıklı kadınlarda egzersiz yarar algısını geliştirmede etkilidir.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"5 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Dental Characteristics of Stroke Patients on the Masticatory System* 中风患者的牙齿特征对咀嚼系统的影响*
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1347254
Ömer Dursun, Erhan Di̇ncer, B. Durmuş, Ela Simay Zengi̇n
{"title":"Effect of Dental Characteristics of Stroke Patients on the Masticatory System*","authors":"Ömer Dursun, Erhan Di̇ncer, B. Durmuş, Ela Simay Zengi̇n","doi":"10.38079/igusabder.1347254","DOIUrl":"https://doi.org/10.38079/igusabder.1347254","url":null,"abstract":"Aim: The aim of this study was to assess the interplay between central facial paralysis and dental characteristics for impaired mastication in sub-acute or chronic-stage stroke patients. \u0000Method: 20 stroke patients and 27 healthy individuals were included in the study. Oral health, oral hygiene, masticatory efficiency, central facial paralysis, and forward head posture of the participants were assessed by OHIP-14 questionnaire, a self-prepared questionnaire, a two-colored chewing gum test, labial commissure, and craniocervical angle measurements. Stroke characteristics and dental characteristics were also assessed.\u0000Results: The sociodemographic and physical characteristics of both groups were similar (p>.05). The dental characteristics of the stroke patients were significantly poor compared to healthy individuals (p<.05). Masticatory efficiency of the stroke patients was nearly half that of the healthy individuals (p<.05). The forward head posture and facial paralysis values of both groups were similar (p>.05).\u0000Conclusion: Our study showed that central facial paralysis gradually loses its effect on impaired mastication in stroke patients and gives its place to dental characteristics. Masticatory muscle activation and increasing postural adaptations like forward head posture may not be preferred by stroke patients. The preferred mastication side might be used to assess the severity or existence of central facial paralysis in stroke patients.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"76 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The SH-SY5Y Human Cell Line: Hawthorne Berry (Crataegus spp.) Protects against 6-OHDA Induced Neurotoxicity In Vitro Model of Parkinson's Disease SH-SY5Y人类细胞系:山楂果实(山楂属)可保护帕金森病体外模型免受6-OHDA诱导的神经毒性影响
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1308558
Yesim Yeni, Ahmet Hacimüftüoğlu
{"title":"The SH-SY5Y Human Cell Line: Hawthorne Berry (Crataegus spp.) Protects against 6-OHDA Induced Neurotoxicity In Vitro Model of Parkinson's Disease","authors":"Yesim Yeni, Ahmet Hacimüftüoğlu","doi":"10.38079/igusabder.1308558","DOIUrl":"https://doi.org/10.38079/igusabder.1308558","url":null,"abstract":"Aim: We purposed to study the neuroprotective effects of Hawthorn berry (crataegus spp.) extract, which is familiar to have antioxidant and anti-inflammatory features, opposite the neurotoxicity led to by 6-OHDA in SH-SY5Y cells.\u0000Method: SH-SY5Y cells were treated with Hawthorn berry (25-50-75 and 100 μg/mL) for two hours ago 6-OHDA administration. Cells were exposed to 200 µM 6-OHDA for 24 hours to mimic the in vitro Parkinson's disease model. After one day, cell viability was measured by lactate dehydrogenase and 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide analysis. Oxidative stress was evaluated with tumor necrosis factor-α, interleukin-1β, superoxide dismutase, catalase, glutathione, glutathione peroxidase, myeloperoxidase, and malondialdehyde assays.\u0000Results: It was found that the viability rate of Hawthorn berry increased depending on the concentration and the cell viability was 94% at the highest concentration (p<0.001). Also, 6-OHDA raised lactate dehydrogenase leakage in SH-SY5Y cells (p<0.001). While 6-OHDA exacerbated oxidative stress by enhancing tumor necrosis factor-α, interleukin-1β, myeloperoxidase, and malondialdehyde (p<0.001), pretreatment with Hawthorn berry alleviated these toxic effects of 6-OHDA through antioxidant capacity by increasing glutathione peroxidase, superoxide dismutase, catalase and glutathione (p<0.05), (p<0.001). In line with all findings, Hawthorn berry attenuated neuronal cell demise in a dose-dependent manner.\u0000Conclusion: Considering its neuroprotective role as well as its effects on oxidative stress, Hawthorn berry could be a potential natural bio-medicine to prevent the development of Parkinson's disease.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"76 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal Kord Yaralanması Olan Bireylerde Epidural Elektriksel Stimülasyon Uygulamasının Etkisi 硬膜外电刺激对脊髓损伤患者的影响
İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi Pub Date : 2024-01-08 DOI: 10.38079/igusabder.1352762
Görkem Açar, Rıfat Mutuş, Gülşah Konakoğlu
{"title":"Spinal Kord Yaralanması Olan Bireylerde Epidural Elektriksel Stimülasyon Uygulamasının Etkisi","authors":"Görkem Açar, Rıfat Mutuş, Gülşah Konakoğlu","doi":"10.38079/igusabder.1352762","DOIUrl":"https://doi.org/10.38079/igusabder.1352762","url":null,"abstract":"Spinal cord injury (SCI) is a significant cause of disability, affecting both children and adults worldwide. These injuries can arise from various conditions, including traumatic, vascular, tumor-related, infection-related, inflammatory (such as multiple sclerosis), or neurodegenerative (like motor neuron disease) origins. Among these, traumatic spinal cord injuries caused by reasons like falls and traffic accidents stand out, particularly in developed countries. Epidural electrical stimulation (EES) was initially used to inhibit chronic pain. Subsequent studies have shown its effectiveness in individuals with SCI. In research spanning from the past to the present, EES applications have been utilized for activities such as motor function improvement, sensory enhancement, bowel functions, increased sexual functionality, and regulating heart rhythms in people with SCI. However, the exact impact of EES remains inconclusive at present and is still a subject of debate.","PeriodicalId":516278,"journal":{"name":"İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi","volume":"74 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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