The Open AIDS Journal最新文献

{"title":"Recurrent Meningitis and Subarachnoid Hemorrhage Due to Salmonella in an HIV+ Patient: Case Report and Mini-Review of the Literature.","authors":"Waldo H Belloso,&nbsp;Marina Romano,&nbsp;Graciela S Greco,&nbsp;Richard T Davey,&nbsp;Ariel G Perelsztein,&nbsp;Marisa L Sánchez,&nbsp;Martín R Ajzenszlos,&nbsp;Inés M Otegui","doi":"10.2174/1874613601105010062","DOIUrl":"https://doi.org/10.2174/1874613601105010062","url":null,"abstract":"<p><p>Meningitis due to non-typhi salmonella is infrequent in HIV-positive adults.We report a case of a patient with >300 CD4+ cells/mm3 who presented with five episodes of recurrent meningitis, focal subarachnoid hemorrhage and cerebral vasculitis ultimately attributed to Salmonella choleraesuis infection. Even within the cART era invasive salmonellosis can occur in unusual ways in HIV-infected patients.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"62-6"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/76/TOAIDJ-5-62.PMC3139252.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30019336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-cirrhotic portal hypertension in human immunodeficiency virus-infected patients: a new challenge in antiretroviral therapy era.","authors":"Hortensia Alvarez Díaz,&nbsp;Ana Mariño Callejo,&nbsp;José Francisco García Rodríguez","doi":"10.2174/1874613601105010059","DOIUrl":"https://doi.org/10.2174/1874613601105010059","url":null,"abstract":"<p><p>Non-cirrhotic portal hypertension (NCPH) has been recently reported as a liver disease in Human Immunodeficiency Virus (HIV)-infected patients under antiretroviral therapy (ART). Combination of non-exclusive mechanisms has been described: primary endothelial damage of terminal portal veins induced by HIV or immunologic disorders, mitochondrial toxicity by didanosine and prothrombotic state. It is characterized by heterogeneous liver histological findings, frequently identified as nodular regenerative hyperplasia and clinical manifestations of portal hypertension with well-preserved liver function. We describe herein two HIV-infected patients with clinical picture suggestive of NCPH. Besides the case reports, we briefly address questions to apply to patient care in clinical practice.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/dd/TOAIDJ-5-59.PMC3134955.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30008330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Pregnant Women on Mother-to-Child Transmission of HIV in Yaoundé.","authors":"Anne-Cirènecile Zoung-Kanyi Bissek,&nbsp;Irène Emah Yakana,&nbsp;Franscisca Monebenimp,&nbsp;Guillaume Chaby,&nbsp;Linda Akondeng,&nbsp;Samuel A Angwafor,&nbsp;Catherine Lok,&nbsp;Alfred K Njamnshi,&nbsp;Walinjom F T Muna","doi":"10.2174/1874613601105010025","DOIUrl":"https://doi.org/10.2174/1874613601105010025","url":null,"abstract":"<p><strong>Introduction: </strong>Mother-to-child transmission of HIV is a major public health problem in Cameroon. The aim of this study was to assess knowledge of pregnant women on HIV transmission and prevention, particularly the four pillars of mother-to-child transmission.</p><p><strong>Materials and methods: </strong>This was a descriptive cross-sectional study from October 2008 to January 2009 at the Yaoundé Gynaecology-Obstetrics and Pediatric Hospital. All women presenting at the Ante-Natal Care (ANC) Clinic for the first time were included in the study after obtaining a verbal informed consent.</p><p><strong>Results: </strong>The ages of the 260 women included in the study ranged from 15 to 42 years. Almost 99% (257/260) of the women interviewed had heard about HIV. Respectively, 80.5% (209/260), 89.3% (232/260) and 81.2% (211/260) of the women cited pregnancy, delivery, and breastfeeding as risk periods for HIV transmission from mother to child. Use of the male condom, the female condom, abstinence, and faithfulness to a single partner were considered as effective methods of HIV prevention by 73% (190/260), 76% (198/260), 88% (229/260) and 46% (120/260) of respondents respectively. About 79% (64/81) of participants with higher education considered HIV infection to be contagious as opposed to 45.5% (5/11) of women with no formal education (P = 0.008).</p><p><strong>Conclusion: </strong>Our data suggest that women have some good knowledge on the Prevention of Mother-To-Child Transmission (PMTCT) of HIV. Nevertheless, improving the formal educational level of these women may contribute to a further reduction of HIV transmission.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"25-8"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/45/TOAIDJ-5-25.PMC3103904.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30216741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV Screening and Awareness Survey for Pregnant Women in a Remote Area in Xinjiang Uyghur Autonomous Region of China.","authors":"Yuping Sun,&nbsp;Karlene Hewan-Lowe,&nbsp;Qiang Wu,&nbsp;Jiang Yu,&nbsp;Zhiqiu Guo,&nbsp;Yali Han,&nbsp;Yujiang Fan,&nbsp;Xianfang Qin,&nbsp;Ping Xu,&nbsp;Janati Bolatihan,&nbsp;Mayinuer Hoshaerbai,&nbsp;Luping Yuan,&nbsp;Heng Hong","doi":"10.2174/1874613601105010096","DOIUrl":"https://doi.org/10.2174/1874613601105010096","url":null,"abstract":"<p><strong>Objective: </strong>The number of people infected with human immunodeficiency virus (HIV) in China has increased in recent years. HIV screening for pregnant women was performed in a remote area in Xinjiang, as an effort to promote universal HIV screening in pregnant women and to help prevention of mother-to-child transmission.</p><p><strong>Methods: </strong>Pregnant women in Burqin and Jeminay Counties in Xinjiang were offered free voluntary HIV screening. Local mid-level medical workers were trained to use Determine® HIV-1/2 kit for HIV screening. All the tested pregnant women signed a consent form, received HIV education material, and participated in an HIV knowledge survey.</p><p><strong>Results: </strong>All the 890 pregnant women receiving HIV test had negative result. Among these women, 67.6% were Kazakh and 40.9% were farmers. Survey of HIV knowledge showed that these women's awareness about mother-to-child transmission was limited. The levels of HIV knowledge were related with ethnic background, age, education and profession of the pregnant women.</p><p><strong>Conclusion: </strong>The results suggested that HIV infection had not become a significant problem among the pregnant women in this remote area of Xinjiang, but continued efforts to improve the awareness of HIV, especially the knowledge about mother-to-child transmission of HIV, in pregnant women were needed.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"96-101"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/cc/TOAIDJ-5-96.PMC3242400.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30355627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Realities and Challenges of a Five Year Follow Up of Mother and Child Pairs on a PMTCT Program in Zimbabwe.","authors":"E N Kurewa,&nbsp;G Q Kandawasvika,&nbsp;F Mhlanga,&nbsp;M Munjoma,&nbsp;M P Mapingure,&nbsp;P Chandiwana,&nbsp;M Z Chirenje,&nbsp;S Rusakaniko,&nbsp;B Stray-Pedersen","doi":"10.2174/1874613601105010051","DOIUrl":"https://doi.org/10.2174/1874613601105010051","url":null,"abstract":"<p><strong>Background: </strong>Complete follow up is an essential component of observational cohorts irrespective of the type of disease.</p><p><strong>Objectives: </strong>To describe five years follow up of mother and child pairs on a PMTCT program, highlighting loss to follow up (LTFU) and mortality (attrition).</p><p><strong>Study design: </strong>A cohort of pregnant women was enrolled from the national PMTCT program at 36 weeks gestational age attending three peri urban clinics around Harare offering maternal and child health services. Mother-infant pairs were followed up from birth and twice yearly for five years.</p><p><strong>Results: </strong>A total of 479 HIV infected and 571 HIV negative pregnant women were enrolled, 445(92.9%) and 495(86.6%) were followed up whereas 14(3.0%) and 3(0.5%) died in the 1st year respectively; RR (95%CI) 5.3(1.5-18.7). At five years 227(56.7%) HIV infected and 239(41.0%) HIV negative mothers turned up, whereas mortality rates were 34 and 7 per 100 person years respectively. Birth information was recorded for 401(83.7%) HIV exposed and 441(77.2%) unexposed infants, 247(51.6%) and 232(40.6) turned up in the first year whilst mortality was 58(12.9%) and 22(4.4%) respectively, RR (95%CI) 3.2(2.0-5.4). At five years 210(57.5%) HIV exposed and 239(44.3%) unexposed infants were seen, whilst mortality rates were 53 per 1000 and 15 per 1 000 person years respectively. Mortality rate for HIV infected children was 112 compared to 21 per 1 000 person years for the exposed but uninfected.</p><p><strong>Conclusion: </strong>HIV infected mothers and their children succumbed to mortality whereas the HIV negatives were LTFU. Mortality rates and LTFU are high within PMTCT program.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"51-8"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bd/fc/TOAIDJ-5-51.PMC3134989.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30008329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV/AIDS Clinical Manifestations and their Implication for Patient Clinical Staging in Resource Limited Settings in Tanzania.","authors":"Idindili Boniphace,&nbsp;Minzi Omari,&nbsp;Rumisha Susan Fred,&nbsp;Mugusi Ferdinand,&nbsp;Tanner Marcel","doi":"10.2174/1874613601105010009","DOIUrl":"https://doi.org/10.2174/1874613601105010009","url":null,"abstract":"<p><strong>Background: </strong>Tanzania HIV/AIDS management follows WHO clinical staging which requires CD4 counts as complement. Lacking CD4 counts facilities in rural health facilities remains a challenge. Simplified and sensitive clinical staging based on local clinical patterns is useful to ensure effective care without CD4 counts.</p><p><strong>Objectives: </strong>To assess whether local HIV clinical manifestations can be used to guide HIV management in settings with limited access to CD4 counts in Tanzania.</p><p><strong>Methods: </strong>A Cross-sectional study conducted at Tumbi and Chalinze health facilities documented clinical manifestations and CD4 counts in 360 HIV/AIDS patients. Simplified management groups comprised of severe and moderate disease were formed based on clinical manifestations and CD4 counts results. Symptoms with high frequency were used to predict severe disease.</p><p><strong>Results: </strong>A Weight loss (48.3%) and chronic cough (40.8 %) were the most reported manifestations in the study population. More than 50% of patients presented with CD4≤200. Most symptoms were found to be highly sensitive (71% to 93%) in predicting severe immunosuppression using CD4<200 cut-off point as a 'Gold standard'. Chronic diarrhoea presented in 10.6%, and predicted well severe immunosuppression either alone (OR 1.95, 95%CI, 0.95-4.22) or in combination (OR 4.21, 95%CI 0.92-19.33) with other symptoms. Basing strictly on WHO clinical staging 30.8% of patients were detected to be severely immunosuppressed (Stage 4). While using our proposed management categories of severe and moderate immunosuppression 70% of patients were put into the severe immunosuppression group, consistent with CD4 cut-off count of≤350.</p><p><strong>Conclusions: </strong>HIV/AIDS clinics managing large cohorts should develop validated site specific guidelines based on local experiences. Simplified guidelines are useful for resource constrained settings without CD4 counting facilities.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874613601105010009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30208143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of HIV Infection Among Sexually Active Adults in Kenya: A National Population-Based Survey.","authors":"Tom Oluoch,&nbsp;Ibrahim Mohammed,&nbsp;Rebecca Bunnell,&nbsp;Reinhard Kaiser,&nbsp;Andrea A Kim,&nbsp;Anthony Gichangi,&nbsp;Mary Mwangi,&nbsp;Sufia Dadabhai,&nbsp;Lawrence Marum,&nbsp;Alloys Orago,&nbsp;Jonathan Mermin","doi":"10.2174/1874613601105010125","DOIUrl":"https://doi.org/10.2174/1874613601105010125","url":null,"abstract":"<p><strong>Objective: </strong>To identify factors associated with prevalent HIV in a national HIV survey in Kenya.</p><p><strong>Methods: </strong>The Kenya AIDS Indicator Survey was a nationally representative population-based sero-survey that examined demographic and behavioral factors and serologic testing for HIV, HSV-2 and syphilis in adults aged 15-64 years. We analyzed questionnaire and blood testing data to identify significant correlates of HIV infection among sexually active adults.</p><p><strong>Results: </strong>Of 10,957 eligible women and 8,883 men, we interviewed 10,239 (93%) women and 7,731 (87%) men. We collected blood specimens from 9,049 women and 6,804 men of which 6,447 women and 5,112 men were sexually active during the 12 months prior to the survey. HIV prevalence among sexually active adults was 7.4%. Factors independently associated with HIV among women were region (Nyanza vs Nairobi: adjusted OR [AOR] 1.6, 95%CI 1.1-2.3), number of lifetime sex partners (6-9 vs 0-1 partners: AOR 3.0, 95%CI 1.6-5.9), HSV-2 (AOR 6.5, 95%CI 4.9-8.8), marital status (widowed vs never married: AOR 2.7, 95%CI 1.5-4.8) and consistent condom use with last sex partner (AOR 2.3, 95%CI 1.6-3.4). Among men, correlates of HIV infection were 30-to-39-year-old age group (AOR 5.2, 95%CI 2.6-10.5), number of lifetime sex partners (10+ vs 0-1 partners, AOR 3.5, 95%CI 1.4-9.0), HSV-2 (AOR 4.7, 95%CI 3.2-6.8), syphilis (AOR 2.4, 95%CI 1.4-4.0), consistent condom use with last sex partner (AOR 2.1, 95% CI 1.5-3.1) and lack of circumcision (AOR 4.0, 95%CI 2.8 - 5.5).</p><p><strong>Conclusion: </strong>Kenya's heterogeneous epidemic will require regional and gender-specific prevention approaches.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"125-34"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/9a/TOAIDJ-5-125.PMC3257551.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30393487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple ART Programs Create a Dilemma for Providers to Monitor ARV Adherence in Uganda.","authors":"Celestino Obua,&nbsp;Annelie Gusdal,&nbsp;Paul Waako,&nbsp;John C Chalker,&nbsp;Goran Tomson,&nbsp;Rolf Wahlström,&nbsp;The Inrud-Iaa Team","doi":"10.2174/1874613601105010017","DOIUrl":"https://doi.org/10.2174/1874613601105010017","url":null,"abstract":"<p><strong>Background: </strong>Increased availability and accessibility of antiretroviral therapy (ART) has improved the length and quality of life amongst people living with HIV/AIDS. This has changed the landscape for care from episodic to long-term care that requires more monitoring of adherence. This has led to increased demand on human resources, a major problem for most ART programs. This paper presents experiences and perspectives of providers in ART facilities, exploring the organizational factors affecting their capacity to monitor adherence to ARVs.</p><p><strong>Methods: </strong>From an earlier survey to test adherence indicators and rank facilities as good, medium or poor adherence performances, six facilities were randomly selected, two from each rank. Observations on facility set-up, provider-patient interactions and key informant interviews were carried out. The strengths, weaknesses, opportunities and threats identified by health workers as facilitators or barriers to their capacity to monitor adherence to ARVs were explored during group discussions.</p><p><strong>Results: </strong>Findings show that the performance levels of the facilities were characterized by four different organizational ART programs operating in Uganda, with apparent lack of integration and coordination at the facilities. Of the six facilities studied, the two high adherence performing facilities were Non-Governmental Organization (NGO) programs, while facilities with dual organizational programs (Governmental/NGO) performed poorly. Working conditions, record keeping and the duality of programs underscored the providers' capacity to monitor adherence. Overall 70% of the observed provider-patient interactions were conducted in environments that ensured privacy of the patient. The mean performance for record keeping was 79% and 50% in the high and low performing facilities respectively. Providers often found it difficult to monitor adherence due to the conflicting demands from the different organizational ART programs.</p><p><strong>Conclusion: </strong>Organizational duality at facilities is a major factor in poor adherence monitoring. The different ART programs in Uganda need to be coordinated and integrated into a single well resourced program to improve ART services and adherence monitoring. The focus on long-term care of patients on ART requires that the limitations to providers' capacity for monitoring adherence become central during the planning and implementation of ART programs.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"17-24"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/21/TOAIDJ-5-17.PMC3103899.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30208144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV Prevalence Comparison Between Antenatal Sentinel Surveillance and Demographic and Health Survey in Rwanda.","authors":"Jeanne Françoise Kayibanda,&nbsp;Michel Alary,&nbsp;Raphaël Bitera,&nbsp;Adeline Kabeja,&nbsp;Ruton Hinda,&nbsp;Louis Munyakazi,&nbsp;Bassirou Chitou,&nbsp;Jean Philippe Gatarayiha","doi":"10.2174/1874613601105010029","DOIUrl":"https://doi.org/10.2174/1874613601105010029","url":null,"abstract":"<p><strong>Objective: </strong>To compare HIV prevalence from antenatal surveillance to that of the demographic and health survey (DHS), and to identify factors determining the difference of HIV prevalence between women recruited in these two surveys in Rwanda in 2005.</p><p><strong>Methods: </strong>Comparative cross-sectional study of HIV prevalence and socio-demographic factors collected by the antenatal survey in 13,745 pregnant women, seen in 30 health centres located throughout the country and those collected by the DHS among 5641 women, aged 15-49 years living in households located throughout the country. Log-binomial regression and direct standardization were used to estimate and compare HIV prevalence between the two surveys.</p><p><strong>Results: </strong>HIV prevalence in the antenatal survey was slightly higher than that in DHS women (4.1% versus 3.6% p=0.103). Socio-demographic characteristics were differently distributed between the two populations. Whereas, 59%, 93%, 53% of pregnant women were aged 20-29 years, married or cohabiting and living in rural areas respectively, the corresponding proportions among DHS women were 35%, 48% and 83% (p<0.001). Simultaneous standardization of antenatal prevalence according to the distribution of socio-demographic characteristics in the DHS gave an overall HIV prevalence estimate of 3.6%, similar to the prevalence measured among DHS women.</p><p><strong>Conclusions: </strong>HIV prevalence in the antenatal survey overestimated that among women of the general population in Rwanda in 2005. This overestimation could be corrected by standardization of antenatal prevalence according to the distribution of age, geographical area, marital status, parity, and education, in the general population.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/cd/TOAIDJ-5-29.PMC3103890.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30216739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning from Interviews with HIV-Discordant Couples (Male Positive, Female Negative): The Challenges and Successes.","authors":"Sandy N Tecimer,&nbsp;Denise Jaworsky,&nbsp;Trent Newmeyer,&nbsp;Steven Chihrin,&nbsp;Kevin Gough,&nbsp;Anita Rachlis,&nbsp;James Martin,&nbsp;Saira Mohammed,&nbsp;Mona R Loutfy","doi":"10.2174/1874613601105010037","DOIUrl":"https://doi.org/10.2174/1874613601105010037","url":null,"abstract":"<p><p>This article examines the challenges and successes of recruiting participants and maintaining momentum in a small qualitative study on the experiences of HIV-discordant couples (where the male is HIV-positive and the female is HIV-negative) undergoing fertility assessment and/or treatment in Ontario, Canada, to reduce the risk of HIV transmission to the woman and fetus. The purpose of this article is to identify barriers and successes encountered in our study, consider how these are addressed in the literature, and highlight specific factors that need to be considered when studying a unique population similar to ours.</p>","PeriodicalId":515834,"journal":{"name":"The Open AIDS Journal","volume":"5 ","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/56/TOAIDJ-5-37.PMC3103905.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30208145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}