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Accounting for uncertainty in conflict mortality estimation: an application to the Gaza War in 2023-2024. 考虑冲突死亡率估计中的不确定性:2023-2024年加沙战争的应用。
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-10-13 DOI: 10.1186/s12963-025-00422-9
Ana C Gómez-Ugarte, Irena Chen, Enrique Acosta, Ugofilippo Basellini, Diego Alburez-Gutierrez
{"title":"Accounting for uncertainty in conflict mortality estimation: an application to the Gaza War in 2023-2024.","authors":"Ana C Gómez-Ugarte, Irena Chen, Enrique Acosta, Ugofilippo Basellini, Diego Alburez-Gutierrez","doi":"10.1186/s12963-025-00422-9","DOIUrl":"10.1186/s12963-025-00422-9","url":null,"abstract":"<p><p>The ongoing Gaza War has resulted in significant loss of life and intensified an existing humanitarian crisis. Despite increasing demand for accurate data, mortality estimates remain challenging due to the inherent 'statistical fog of war'. Accurate quantification is hindered by incomplete reporting and uncertain age-sex distributions of casualties. Official death tolls are likely influenced by damaged infrastructure, security disruptions, and political motivations, complicating detailed demographic verification. Our study introduces a novel methodological approach-a Bayesian model incorporating novel priors-to explicitly account for measurement errors in mortality estimation by addressing reporting completeness and uncertainty in demographic distributions. We use these methods to estimate sex- and age-specific mortality patterns and associated life expectancy (LE) and LE losses due to direct conflict deaths from the Gaza War. We find that LE in Gaza was 42.3 (39.4-45.0) in 2023 and 40.4 (37.5-43.0) in 2024, corresponding to LE losses of 34.4 (31.7-37.3) and 36.4 (33.8-39.3) years, respectively, compared to a counterfactual scenario with no conflict-related deaths. This corresponds to 78,318 (70,614-87,504) conflict deaths by the end of 2024, reflecting a 14-fold increase in all-cause mortality during the conflict's first year. The age-sex pattern of Gaza's conflict deaths aligns with UN-IGME profiles from past genocides. To contextualize these estimates, we compare them with LE losses observed in the Gaza Strip, the West Bank, and all of Palestine between 2012 and 2019. Our estimates align with previously published work, after adjusting the reporting priors to ignore underreporting. Our versatile and robust framework for mortality estimation under conditions of data scarcity can inform future conflict research.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"55"},"PeriodicalIF":2.5,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12516881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving racial data equity among minority groups in South Carolina using COVID-19 as an example: application of principal components analysis. 改善南卡罗来纳州少数族裔群体的种族数据公平——以COVID-19为例:主成分分析的应用
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-10-09 DOI: 10.1186/s12963-025-00419-4
Fnu Rubaiya, Janet O'Connor, Lyubomir N Kolev, James M Antill, Margaret Iiams, LaNaya A Martin, Chantaezia Z Joseph, Claire Youngblood, Jennifer Almeda-Garrett, Linda E Kelemen
{"title":"Improving racial data equity among minority groups in South Carolina using COVID-19 as an example: application of principal components analysis.","authors":"Fnu Rubaiya, Janet O'Connor, Lyubomir N Kolev, James M Antill, Margaret Iiams, LaNaya A Martin, Chantaezia Z Joseph, Claire Youngblood, Jennifer Almeda-Garrett, Linda E Kelemen","doi":"10.1186/s12963-025-00419-4","DOIUrl":"10.1186/s12963-025-00419-4","url":null,"abstract":"<p><strong>Background: </strong>Data inequity occurs when racial and ethnic groups are aggregated during data collection or reporting despite their differences. To demonstrate racial data equity importance, we re-analyzed South Carolina's (SC) census data and COVID-19 case-rate and death-rate distributions according to age, sex, and new combined single and multiracial categories.</p><p><strong>Methods: </strong>The new combined single and multiracial categories included individuals who identified as a single race alone (such as American Indian or Alaska Native, AI-AN) with those who identified as more than one race (such as AI-AN and White) regardless of Hispanic or Latino heritage. We compared those distributions to the single race categories using the American Community Survey 2018-2022 and COVID-19 case and death surveillance data, 2020-2023, for SC. We used principal components analysis to test for differences in age-sex distributions between single race alone and new combined single and multiracial categories for each race.</p><p><strong>Results: </strong>Compared to the combined single and multiracial categories, single race alone categories lose information, underestimate the population of younger-aged people of AI-AN, Asian, and Native Hawaiian or Other Pacific Islander (NH-OPI) races, and result in COVID-19 case and death rates with extreme values across age groups, particularly for AI-AN and NH-OPI populations. Among AI-AN, certain age groups had different COVID-19 case rate patterns between females and males, but this was explained by race categorization (single race alone vs. combined single and multiracial, P < 0.0001).</p><p><strong>Conclusions: </strong>Combined single and multiracial categories achieve data equity by avoiding data suppression or aggregation of small diverse populations. Differences in COVID-19 case rates across some age groups between females and males may be biased depending on how race is defined. Younger generations are increasingly multiracial and will be underrepresented if only single race categories are used in public health reporting practices.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"54"},"PeriodicalIF":2.5,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimates of non-communicable disease expenditure by disease phase, sex, and age group for all OECD countries. 所有经合组织国家按疾病阶段、性别和年龄组分列的非传染性疾病支出估计数。
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-10-08 DOI: 10.1186/s12963-025-00418-5
Samantha Grimshaw, Emily Bourke, Tony Blakely
{"title":"Estimates of non-communicable disease expenditure by disease phase, sex, and age group for all OECD countries.","authors":"Samantha Grimshaw, Emily Bourke, Tony Blakely","doi":"10.1186/s12963-025-00418-5","DOIUrl":"10.1186/s12963-025-00418-5","url":null,"abstract":"<p><strong>Background: </strong>NCD expenditure estimates are necessary to estimate future health system expenditure trajectories for different prevention and treatment policies. However, no dataset of comparable estimates exists across OECD countries. This study generates disease expenditure estimates for all 38 OECD member countries in 2019, for 80 major NCDs by disease phase, sex, and age group.</p><p><strong>Methods: </strong>Australian health expenditure (per person) by sex and age group was disaggregated by disease phase (first year of diagnosis, last year of life if dying of disease, otherwise prevalent) using Global Burden of Disease (GBD) data and New Zealand estimates of relative expenditure ratios by phase. These estimates were applied to GBD estimated case numbers in each OECD country and scaled to each country's total health system expenditure to estimate expenditure by NCDs in 2019. OECD purchasing power parities were used to adjust estimates to United States (US) dollars for cross-country comparability. Comparisons were made to pre-existing disease expenditure estimates for Norway, Switzerland, and the US.</p><p><strong>Results: </strong>Average NCD expenditure across OECD countries was US$207 million per 100,000 population. Pooled across countries, musculoskeletal disorders had the highest proportion of total health expenditure (17.4%), followed by cancer (9.4%), and cardiovascular diseases (CVD) (9.1%). Within diseases, the percentage of expenditure was higher for females for musculoskeletal disorders (56.1%), mental and substance use disorders (55.8%), and neurological conditions (54.8%). For males, it was kidney and urinary diseases (63.8%), cancer (58.3%), and CVD (50.7%). First year of diagnosis represented on average 36.8% of total NCD expenditure, while last year of life expenditure accounted for 2.6%. While there were similarities between our expenditure estimates and pre-existing country-specific estimates for Norway, Switzerland and the US, notable differences were observed for musculoskeletal disorders, cancer, and mental and substance use disorders.</p><p><strong>Conclusions: </strong>Our estimates represent a starting point for a cross-national dataset of disease-specific expenditure that can be used to forecast future expenditure and potential health system cost savings of preventive and treatment policies. We recommend evolving our paper's methods to include multiple country-level studies as inputs - augmented by covariates (e.g. GDP, public/private split) to better predict disease expenditure.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"53"},"PeriodicalIF":2.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological trends and determinants of suicide in Iran with insights into the COVID-19 period, 1980-2021. 伊朗自杀的流行病学趋势和决定因素:对1980-2021年2019冠状病毒病期间的洞察
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-09-15 DOI: 10.1186/s12963-025-00416-7
Kiavash Hushmandi, Parviz Shahmirzalou, Yousef Ramazani, Rasoul Raesi, Mahdieh Ardaneh, Hedyeh Askarpour, Salman Daneshi
{"title":"Epidemiological trends and determinants of suicide in Iran with insights into the COVID-19 period, 1980-2021.","authors":"Kiavash Hushmandi, Parviz Shahmirzalou, Yousef Ramazani, Rasoul Raesi, Mahdieh Ardaneh, Hedyeh Askarpour, Salman Daneshi","doi":"10.1186/s12963-025-00416-7","DOIUrl":"10.1186/s12963-025-00416-7","url":null,"abstract":"<p><strong>Introduction: </strong>Suicide is a significant global health issue, responsible for 759,028 deaths worldwide in 2019. In Iran, suicide rates have fluctuated significantly from 1980 to 2020, influenced by social, economic, and psychological factors. Adolescents and young adults, in particular, face high suicide rates related to financial problems and mental health disorders. This study aims to identify trends in suicide changes in Iran and the factors influencing them.</p><p><strong>Methods: </strong>A mixed-methods approach was employed, with data collected from reputable sources such as the Ministry of Health and non-governmental organizations. Analytical methods included statistical software (SPSS and R) using ARIMA modeling and Joinpoint regression to assess trends, as well as the Augmented Dickey-Fuller test to ensure data stationarity.</p><p><strong>Results: </strong>The analysis revealed that from 1980 to 2021, suicide rates in Iran declined, although women generally had higher rates than men. The highest suicide rate was observed in the age group of 20-24 years. Time series models predict that suicide rates will increase in the next five years, influenced by factors such as economic crises and the COVID-19 pandemic.</p><p><strong>Conclusion: </strong>This study shows that despite an overall decline in suicide rates, certain groups remain at high risk. The predicted increase in suicide rates highlights the need for urgent interventions to address economic and psychological issues, as well as reduce the social stigma associated with mental health. A detailed analysis of data is crucial for developing effective preventive strategies to reduce suicide rates in Iran.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"52"},"PeriodicalIF":2.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disaggregated level child morbidity in Zambia: an application of small area estimation method. 赞比亚儿童发病率的分类水平:小面积估算法的应用。
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-08-28 DOI: 10.1186/s12963-025-00413-w
Audrey M Kalindi, Sumonkanti Das
{"title":"Disaggregated level child morbidity in Zambia: an application of small area estimation method.","authors":"Audrey M Kalindi, Sumonkanti Das","doi":"10.1186/s12963-025-00413-w","DOIUrl":"https://doi.org/10.1186/s12963-025-00413-w","url":null,"abstract":"<p><strong>Background: </strong>High rates of child morbidity and developmental challenges among children under five remain critical challenges in sub-Saharan Africa. Despite Zambia's progress in reducing under-five morbidity, the rates remain high, with provincial-level disparities. These disparities are likely to be more pronounced at finer geographic levels, such as districts. However, demographic health surveys, designed for national and provincial estimates, lack sufficient data to produce reliable district-level morbidity statistics.</p><p><strong>Objective: </strong>This study investigates the geospatial distribution of child morbidity prevalence across disaggregated administrative units using small area estimation (SAE) methods.</p><p><strong>Data and methods: </strong>Data from the 2018 Zambia Demographic and Health Survey and the 2010 Zambian Census were used to derive direct estimates of child morbidity for small domains cross-classified by district and age group. A hierarchical Bayesian SAE model was developed to account for spatial and unobserved heterogeneity at provincial and district levels, including cross-classifications by age group.</p><p><strong>Results: </strong> Model-based estimates show lower standard errors compared to the direct estimates and significant differences in morbidity levels within and between districts and provinces. Under-five morbidity prevalence remains high at 25%, with the highest rates in Luapula (approximately 40%) and Western provinces (around 35%) and among children aged 11-23 months (nearly 40%). SAE estimates at the district and district-by-age levels were numerically consistent when aggregated to higher levels, such as province or child age group.</p><p><strong>Conclusion: </strong>These data-driven detailed level estimates provide critical insights into the spatial distribution of child morbidity, supporting targeted interventions and informed policymaking at disaggregated levels.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"51"},"PeriodicalIF":2.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative impact of social isolation on mortality in adults aged 40 years and above with versus without metabolic syndrome: evidence from two large cohorts in the U.S. and U.K. 社会隔离对40岁及以上有与无代谢综合征的成年人死亡率的比较影响:来自美国和英国两个大型队列的证据
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-08-25 DOI: 10.1186/s12963-025-00414-9
Siying Liu, Cihang Lu, Bingxin You, Qiqiang Guo, Tingting Liu, Yongze Li
{"title":"Comparative impact of social isolation on mortality in adults aged 40 years and above with versus without metabolic syndrome: evidence from two large cohorts in the U.S. and U.K.","authors":"Siying Liu, Cihang Lu, Bingxin You, Qiqiang Guo, Tingting Liu, Yongze Li","doi":"10.1186/s12963-025-00414-9","DOIUrl":"https://doi.org/10.1186/s12963-025-00414-9","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Social isolation is increasingly recognized as a significant public health concern associated with mortality risk. However, whether the impact of social isolation on mortality differs between individuals with and without metabolic syndrome (MetS) remains unclear. This study aimed to investigate the associations of social isolation with all-cause mortality, cardiovascular mortality (CVDM), cancer mortality (CAM), other cause mortality (OTM), and premature mortality in MetS and non-MetS populations using data from large cohorts in the UK and the US.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study analyzed data from 75,190 participants with metabolic syndrome (MetS) and 229,388 participants without MetS in the UK Biobank, as well as 5758 MetS participants and 7448 non-MetS participants from the U.S. National Health and Nutrition Examination Survey (NHANES). All participants included in the study were aged 40 years or above. The identification of MetS was based on a comprehensive assessment of multiple biochemical indicators, including waist circumference, blood glucose, blood pressure, and blood lipid levels. Social isolation was evaluated using information on marital status, household size, frequency of contact with family and friends, and engagement in social activities. The primary outcomes included all-cause mortality, cardiovascular mortality, cancer mortality, other-cause mortality, and premature mortality, defined as death before the age of 70. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations between social isolation and various mortality outcomes. In addition, interaction and subgroup analyses were conducted to explore the potential modifying effects of MetS status, as well as lifestyle and other risk factors, on the relationship between social isolation and mortality.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the UK Biobank, the rates of all-cause mortality, CVDM, CAM, OTM, and premature mortality among participants with MetS were 9.07%, 1.48%, 4.22%, 3.36%, and 1.98%, respectively; the corresponding rates among participants without MetS were 4.81%, 0.51%, 2.61%, 1.68%, and 2.47%. In NHANES, the respective mortality rates among individuals with MetS were 26.20%, 9.24%, 6.15%, 10.85%, and 13.90%, and among those without MetS were 25.80%, 8.13%, 6.31%, 11.30%, and 14.10%. Cox regression analyses showed that, in the fully adjusted models, social isolation was significantly associated with increased risks of all-cause mortality, CVDM, CAM, OTM, and premature mortality in both individuals with and without MetS. In the UK Biobank, the HRs for participants with MetS were 1.30, 1.21, 1.12, 1.38, and 1.39, respectively; for those without MetS, the HRs were 1.51, 1.75, 1.30, 1.76, and 1.54, respectively. In the U.S. NHANES, the HRs for the MetS group were 1.14, 1.54, 1.48, 1.71, and 1.09, respectively; while for the non-MetS group, the HRs were 1.60","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"50"},"PeriodicalIF":2.5,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the consumer health activation index (CHAI) among community-dwelling adults in primary care clinics in Singapore. 验证消费者健康激活指数(CHAI)在新加坡初级保健诊所的社区居住的成年人。
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-08-25 DOI: 10.1186/s12963-025-00402-z
Justin Guang Jie Lee, Qin Xiang Ng, Nan Luo, Gerald Choon Huat Koh, Ling Jie Cheng
{"title":"Validation of the consumer health activation index (CHAI) among community-dwelling adults in primary care clinics in Singapore.","authors":"Justin Guang Jie Lee, Qin Xiang Ng, Nan Luo, Gerald Choon Huat Koh, Ling Jie Cheng","doi":"10.1186/s12963-025-00402-z","DOIUrl":"https://doi.org/10.1186/s12963-025-00402-z","url":null,"abstract":"<p><strong>Background: </strong>Health activation is an individual's knowledge, skills, and confidence in managing personal health and healthcare. The Consumer Health Activation Index (CHAI) is a freely available, 10-item measure originally developed in the United States. This study aimed to validate CHAI among community-dwelling adults in Singapore, examining its content validity, construct validity and test-retest reliability.</p><p><strong>Methods: </strong>The study was conducted in two phases. In Phase 1, cognitive interviews with nine population health experts and eleven lay participants assessed face and content validity. In Phase 2, a cross-sectional survey of 572 adults, recruited via quota sampling aligned with national census distributions, was conducted. Participants completed the CHAI, EQ-5D-5L, EQ-VAS, and the Internal subscale of the Multidimensional Health Locus of Control (MHLC). Exploratory factor analysis (EFA) with principal axis factoring and varimax rotation, along with Cronbach's alpha, assessed structural validity and internal consistency respectively. Test-retest reliability was evaluated in a subsample of 32 participants, of whom 21 reported stable health status at follow-up.</p><p><strong>Results: </strong>Content validity was acceptable, with a Scale-Level Content Validity Index (S-CVI) of 0.86, although minor wording issues were noted for CHAI items 5, 6, and 10. EFA supported a unidimensional structure, and the CHAI demonstrated strong internal consistency (α = 0.85). CHAI scores showed moderate positive correlations with the MHLC internal subscale (Pearson's r = 0.449) and weak to moderate positive correlations with EQ-5D-5 L and EQ-VAS, (r = 0.171-0.344). Known-group validity was supported by significantly higher CHAI scores among individuals with chronic diseases (p = 0.017). Test-retest reliability was good (ICC = 0.802, 95% CI = 0.544-0.911).</p><p><strong>Conclusion: </strong>In summary, the CHAI is a reliable and valid measure of health activation for community-dwelling adults in Singapore. While overall psychometric performance was robust, minor refinements in phrasing may improve language clarity and cultural applicability. Longitudinal research is recommended to further establish CHAI's utility in both clinical and community local settings.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"49"},"PeriodicalIF":2.5,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive value of anthropometric indices for incident of dyslipidemia: a large population-based study. 人体测量指标对血脂异常事件的预测价值:一项基于人群的大型研究。
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-08-19 DOI: 10.1186/s12963-025-00410-z
Somayeh Ghiasi Hafezi, Atena Ghasemabadi, Negar Soleimani, Maryam Allahyari, Mina Moradi, Amin Mansoori, Rana Kolahi Ahari, Mark Ghamsary, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan
{"title":"Predictive value of anthropometric indices for incident of dyslipidemia: a large population-based study.","authors":"Somayeh Ghiasi Hafezi, Atena Ghasemabadi, Negar Soleimani, Maryam Allahyari, Mina Moradi, Amin Mansoori, Rana Kolahi Ahari, Mark Ghamsary, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan","doi":"10.1186/s12963-025-00410-z","DOIUrl":"10.1186/s12963-025-00410-z","url":null,"abstract":"<p><strong>Introduction: </strong>Dyslipidemia as a modifiable risk factor for chronic non-communicable diseases has become a worldwide concern. We aim to explore different anthropometric measures as predictors of dyslipidemia using various machine learning methods.</p><p><strong>Method: </strong>From the baseline of the Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) study, a total of 9,640 participants were included in the analysis. Among them, 1,388 participants did not have dyslipidemia, while 8,252 participants had dyslipidemia. Various anthropometric indices were examined, including waist-to-height ratio (WHtR), body roundness index (BRI), abdominal volume index (AVI), weight-adjusted waist index (WWI), lipid accumulation product (LAP), visceral adiposity index (VAI), conicity index (C-index), body surface area (BSA), body adiposity index (BAI), and waist-to-hip ratio (WHR). The association between these indices and dyslipidemia was assessed using logistic regression (LR), decision tree (DT), random forest (RF), neural networks (NN), K-nearest neighbors (KNN), and eXtreme Gradient Boosting (XGBoost) models.</p><p><strong>Results: </strong>Based on our LR model, we found that several factors included, BAI, BSA, age, and WHR were significant. For example, for each unit increase in WHR, the odds of dyslipidemia increase by 9 time (OR = 90.29, 95%CI (4.09,21.08)). Additionally, our DT model indicated that BMI was the most influential predictor, followed by age and WHR. The LR model outperforms other models with the highest accuracy (0.89) and AUC-ROC score (0.89), showing strong ability to classify dyslipidemia cases. Feature importance analysis reveals variables like \"BSA\" contribute differently across models, with XGBoost relying more on it than LR. LR's balanced performance makes it the best choice.</p><p><strong>Conclusion: </strong>The findings from machine learning models were in agreement, highlighting the significance of BMI, WHR, BSA, and BAI as key anthropometric indices for predicting dyslipidemia. These indices consistently emerged as strong predictors underscoring their importance in assessing the risk of dyslipidemia.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"48"},"PeriodicalIF":2.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144884288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interplay of social integration, well-being, and fairness in older migrant workers: a four -year longitudinal analysis. 老年农民工社会融合、幸福感和公平性的相互作用:一项为期四年的纵向分析。
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-08-13 DOI: 10.1186/s12963-025-00411-y
Guanghui Shen, Xudong Yang, Jiahui Huang, Juan Fang, Shaochang Wu, Jiayi Tang, Liujun Wu, Wang Wei, Yawen Zhen, Li Chen
{"title":"Interplay of social integration, well-being, and fairness in older migrant workers: a four -year longitudinal analysis.","authors":"Guanghui Shen, Xudong Yang, Jiahui Huang, Juan Fang, Shaochang Wu, Jiayi Tang, Liujun Wu, Wang Wei, Yawen Zhen, Li Chen","doi":"10.1186/s12963-025-00411-y","DOIUrl":"10.1186/s12963-025-00411-y","url":null,"abstract":"<p><p>In China, older migrant workers represent an especially vulnerable group, facing challenges to their quality of life as they grow older and move away from their hometowns. This study aimed to investigate the relationship between social integration, subjective well-being, and subjective fairness over a four-year period in a cohort of 1,394 older Chinese migrant workers aged 50 and older. Latent growth modeling showed a significant positive change over time in all three psychosocial constructs. Additionally, the parallel process latent growth modeling revealed that social integration had an indirect effect on subjective fairness by positively affecting subjective well-being, both at baseline and longitudinally. These findings highlight the crucial roles of social integration and subjective well-being in shaping subjective fairness over time in this marginalized population. Fostering social inclusion and emotional health of older migrants may have cascading benefits for social fairness. The complete longitudinal mediation suggests that improved subjective well-being serves as a mechanism translating increasing social integration into enhanced subjective fairness across the later stages of life. This study adds to our understanding of the psychological factors that can be modified to promote subjective fairness and perceived equality in migrant worker populations.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"47"},"PeriodicalIF":2.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are contributory causes of death in part 2 of the death certificate mediators of chains of morbid events leading to death? 死亡证明第2部分所列的促发性死亡原因是导致死亡的一系列病态事件的中介吗?
IF 2.5 2区 医学
Population Health Metrics Pub Date : 2025-08-07 DOI: 10.1186/s12963-025-00394-w
Elizabet Ukolova
{"title":"Are contributory causes of death in part 2 of the death certificate mediators of chains of morbid events leading to death?","authors":"Elizabet Ukolova","doi":"10.1186/s12963-025-00394-w","DOIUrl":"10.1186/s12963-025-00394-w","url":null,"abstract":"<p><strong>Background: </strong>In the United States, over half of all deaths are attributed to five leading underlying causes of death (at the ICD-3 digit level). However, these underlying causes represent only 25% of the total medical information documented on death certificates. While previous studies have investigated associations between causes of death, none have specifically examined the mechanisms of interaction among these causes. This study aims to explore the role of contributory causes of death recorded in Part 2 of the death certificate in the lethal process.</p><p><strong>Methods: </strong>Working with U.S. Multiple Cause of Death Microdata in 2019, we use causal pie models to model the synergy between multiple causes of death.</p><p><strong>Results: </strong>The findings show how contributory causes in Part 2 affect the sequence of morbid events leading to death. Three broad categories of roles can be distinguished: (i) some contributory causes act as mediators in the chain of morbid events, (ii) others do not exhibit any interaction with the conditions listed in Part 1, and (iii) some might play a role in the development of underlying causes.</p><p><strong>Conclusion: </strong>Contributory causes listed in Part 2 play a crucial role in transitions to terminal morbid states. There is evidence that these are more than just conditions without a direct relationship to the underlying cause of death.</p>","PeriodicalId":51476,"journal":{"name":"Population Health Metrics","volume":"23 1","pages":"46"},"PeriodicalIF":2.5,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12333147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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