The Journal of Neuropsychiatry and Clinical Neurosciences最新文献_第4页

Extracting Apathy From Depression Syndrome in Traumatic Brain Injury by Using a Clustering Method. 用聚类方法提取创伤性脑损伤抑郁综合征中的冷漠。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2022-01-01 Epub Date: 2021-11-19 DOI: 10.1176/appi.neuropsych.21020046

Shiho Ubukata, Keita Ueda, Gaku Fujimoto, Senkei Ueno, Toshiya Murai, Naoya Oishi

{"title":"Extracting Apathy From Depression Syndrome in Traumatic Brain Injury by Using a Clustering Method.","authors":"Shiho Ubukata, Keita Ueda, Gaku Fujimoto, Senkei Ueno, Toshiya Murai, Naoya Oishi","doi":"10.1176/appi.neuropsych.21020046","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.21020046","url":null,"abstract":"Objective: Depression and apathy are common after traumatic brain injury (TBI), and different intervention strategies are recommended for each. However, a differential diagnosis can be difficult in clinical settings, especially given that apathy is considered to be a symptom of depression. In this study, the investigators aimed to isolate apathy from depression among patients with TBI and to examine whether apathy is exclusively associated with the amount of daily activity, as previously reported in the literature.Methods: Eighty-eight patients with chronic TBI completed the Japanese versions of the 21-item Beck Depression Inventory-II (BDI-II) and the Starkstein Apathy Scale (AS). Daily activity was measured with a 24-hour life log. A hierarchical cluster analysis was applied to divide the BDI-II data into separable components, and components' correlations with results of the AS and 24-hour life log scale were evaluated.Results: The BDI-II and AS revealed that 37 patients (42.0%) had both depression and apathy. BDI-II data were classified into four separate clusters (somatic symptoms, loss of self-worth, affective symptoms, and apathy symptoms). Loss of self-worth and apathy symptoms subscores were significantly positively correlated with total AS score (r=0.32, p=0.002, and r=0.52, p<0.001, respectively). The apathy symptoms subscore was significantly correlated with the amount of daily activity (r=-0.29, p=0.009).Conclusions: The findings suggest that the BDI-II can differentiate between apathy and depression among patients with TBI, which is essential when selecting intervention options. Moreover, apathy symptoms predicted patients' real-life daily activity.","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"158-167"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39636720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Delayed-Onset Poststroke Psychosis Presenting as Delusional Disorder. 迟发性脑卒中后精神病表现为妄想障碍。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2021-01-01 Epub Date: 2021-07-02 DOI: 10.1176/appi.neuropsych.20100260

Nichola R Haddad, Rachel Caplan, Maria K Houtchens, Stanley Lyndon

引用次数: 0

Enigmatic Neural Pathways: Potentiating Viral Neuroinvasion Into the CNS. 神秘的神经通路:增强病毒侵入中枢神经系统。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2021-01-01 DOI: 10.1176/appi.neuropsych.21060152

Wilfredo López-Ojeda, Robin A Hurley

引用次数: 0

Speech and Language Therapy for Voice Problems in Parkinson's Disease: A Meta-Analysis. 帕金森病语音问题的言语和语言治疗:一项荟萃分析

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2020-01-01 Epub Date: 2020-05-06 DOI: 10.1176/appi.neuropsych.19020044

Hongyan Xu, Zhuohua Bao, Daye Liang, Mengxia Li, Minguang Wei, Xueqing Ge, Jingli Liu, Jinpin Li

{"title":"Speech and Language Therapy for Voice Problems in Parkinson's Disease: A Meta-Analysis.","authors":"Hongyan Xu, Zhuohua Bao, Daye Liang, Mengxia Li, Minguang Wei, Xueqing Ge, Jingli Liu, Jinpin Li","doi":"10.1176/appi.neuropsych.19020044","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.19020044","url":null,"abstract":"Patients with Parkinson's disease (PD) commonly have speech and voice problems that affect their functional communication and that are not sensitive to pharmacological or neurosurgical treatments. The authors aimed to evaluate the effects of speech and language therapies (SLTs) on dysphonia in patients with PD by analyzing data from published randomized controlled trials (RCTs). Studies in English and Chinese that were related to speech and language treatment for patients with PD were retrieved from PubMed, Embase, Chinese National Knowledge Infrastructure, China Science and Technology Journal Database, Chinese Biomedical Literature Database, and Wanfang Database. On the basis of exclusion criteria, 391 records identified through the search were reduced to 10 studies that included 230 patients in the treatment groups and 205 patients in the control groups. A meta-analysis of data from the 10 studies was performed to examine the effects of SLTs on dysphonia in patients with PD. SLTs increased sound pressure level during sustained phonation, reading of the Rainbow Passage, and monologue 6 months after treatment, enhanced semitone standard deviation during reading of the Rainbow Passage more than 12 months after treatment, and reduced Voice Handicap Index scores among patients with PD with dysphonia problems at least 3 months after treatment. These findings demonstrate the efficacy of SLTs, especially Lee Silverman Voice Treatment, in increasing vocal loudness and functional communication among patients with PD. Further RCTs with large samples and multicenter participation are needed to validate the long-term effects and the efficacy of SLTs among patients with severe PD.","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"344-351"},"PeriodicalIF":2.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.19020044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37907520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Psychiatric Morbidity and Its Prognosis in Posterior Reversible Encephalopathy Syndrome. 后部可逆性脑病综合征的精神发病率及其预后。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2020-01-01 Epub Date: 2020-04-14 DOI: 10.1176/appi.neuropsych.19080184

Roxanne C Keynejad, Anthony S David

{"title":"Psychiatric Morbidity and Its Prognosis in Posterior Reversible Encephalopathy Syndrome.","authors":"Roxanne C Keynejad, Anthony S David","doi":"10.1176/appi.neuropsych.19080184","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.19080184","url":null,"abstract":"Posterior reversible encephalopathy syndrome (PRES) is a clinically and radiologically diagnosed disorder distinguished by subcortical vasogenic cerebral edema. To date, its presentation has been described through summarized neurological categories, such as seizures, headaches, \"confusion,\" and \"altered mental function.\" This retrospective case series identified all cases of clinically confirmed, radiologically diagnosed PRES resulting in treatment in a large teaching hospital from 2010 to 2019. The authors conducted a search for the term \"reversible encephalopathy\" in the hospital clinical radiology information system, followed by an audit of scan reports and clinical records. The most common reasons for psychiatric referral were addictions, acute psychosis, depression, suicidality, and treatment refusal. Multidisciplinary staff should consider PRES as a rare, organic differential diagnosis for acute mental state changes. Physicians should be aware of elevated rates of post-PRES psychiatric symptoms and consider whether psychiatric consultation may enhance recovery.","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"385-388"},"PeriodicalIF":2.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.19080184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37829617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Psychologically Informed Physical Therapy for Children and Adolescents With Functional Neurological Symptoms: The Wellness Approach. 具有功能性神经症状的儿童和青少年的心理知情物理治疗:健康方法。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2020-01-01 Epub Date: 2020-07-28 DOI: 10.1176/appi.neuropsych.19120355

Nicola Gray, Blanche Savage, Stephen Scher, Kasia Kozlowska

{"title":"Psychologically Informed Physical Therapy for Children and Adolescents With Functional Neurological Symptoms: The Wellness Approach.","authors":"Nicola Gray, Blanche Savage, Stephen Scher, Kasia Kozlowska","doi":"10.1176/appi.neuropsych.19120355","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.19120355","url":null,"abstract":"Children with functional neurological disorder (FND) present with motor and sensory neurological symptoms that impair health and physical functioning and that create an ongoing clinical burden for caregivers and hospitals worldwide. Treatment programs for these children involve a multidisciplinary approach with physical therapy as a fundamental component. However, standard musculoskeletal approaches to physical therapy are ineffective or may even exacerbate symptoms because they are unresponsive to the biopsychosocial context in which FND emerges: FND typically occurs in the context of stress, either physical or emotional; symptoms are amplified by attention; and presentations are complicated by psychological factors. Informed, in part, by published guidelines for physical therapy with adult FND patients, this article examines common challenges that arise when working with children: overcoming previous negative encounters in the medical system; avoiding amplification of symptoms by drawing attention to them; and managing comorbid pain, falls, faints, nonepileptic seizures, dizziness, fatigue, and breathlessness, plus psychological symptoms such as anticipatory anxiety and panic attacks. What emerges is a psychologically informed therapeutic approach to physical therapy for children with functional neurological symptoms. This approach prioritizes interpersonal processes and physical therapy techniques that establish a therapeutic relationship and create a safe space for physical therapy, that use indirect physical therapy approaches redirecting the focus of attention away from symptoms and emphasizing the completion of tasks and activities engaging the sick body part indirectly, that tailor the intervention to address the needs and presentation of each particular child, and that integrate psychological interventions to manage common challenges.","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"389-395"},"PeriodicalIF":2.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.19120355","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38206152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Visual Hallucinations and the Role of Medications in Parkinson's Disease: Triggers, Pathophysiology, and Management. 视觉幻觉和药物在帕金森病中的作用:诱因、病理生理学和管理。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2020-01-01 Epub Date: 2020-05-06 DOI: 10.1176/appi.neuropsych.19110316

Alice Powell, Catriona Ireland, Simon J G Lewis

{"title":"Visual Hallucinations and the Role of Medications in Parkinson's Disease: Triggers, Pathophysiology, and Management.","authors":"Alice Powell, Catriona Ireland, Simon J G Lewis","doi":"10.1176/appi.neuropsych.19110316","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.19110316","url":null,"abstract":"Visual hallucinations, which are part of the syndrome of Parkinson's disease (PD) psychosis, affect patients' quality of life and increase the likelihood of residential aged-care placement. The association between visual hallucinations and dopaminergic and other medications that are necessary for the symptomatic management of motor and other symptoms of PD is a common clinical dilemma. While dopaminergic medications have long been associated with PD psychosis, a clear causal link has not been established, and other neurotransmitter systems, particularly noradrenaline, serotonin, and acetylcholine, are implicated and important. A diverse range of demographic and disease-related risk factors, some being modifiable, highlight the complexity of potential underlying pathophysiological processes but also broaden practical options for prevention and treatment that can be multifaceted and individualized. The investigators reviewed the clinical features and epidemiology of visual hallucinations and PD, explored the pathological evidence for dysfunction of multiple neurotransmitter systems that may be relevant to these phenomena, and addressed the potential of medications commonly used in PD to either trigger or treat these symptoms.","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"334-343"},"PeriodicalIF":2.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.19110316","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37907519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Of Ghost Grandparents and Missing Limbs. 幽灵祖父母和断肢。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2020-01-01 Epub Date: 2020-05-13 DOI: 10.1176/appi.neuropsych.20030044

Miguel Restrepo-Martínez

引用次数: 0

Clinical Application of Findings From Longitudinal Studies of Younger-Onset Dementia: Rapid Review and Recommendations. 年轻发病痴呆纵向研究结果的临床应用:快速回顾和建议。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2020-01-01 Epub Date: 2020-05-13 DOI: 10.1176/appi.neuropsych.19110238

Samantha M Loi, Anita M Y Goh, Mark Walterfang, Dennis Velakoulis

{"title":"Clinical Application of Findings From Longitudinal Studies of Younger-Onset Dementia: Rapid Review and Recommendations.","authors":"Samantha M Loi, Anita M Y Goh, Mark Walterfang, Dennis Velakoulis","doi":"10.1176/appi.neuropsych.19110238","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.19110238","url":null,"abstract":"Younger-onset dementia (YOD) presents with heterogeneous symptoms, has a variety of etiologies, and can be difficult to diagnose. The authors conducted a rapid review of longitudinal YOD cohorts and their related substudies to evaluate current literature that may inform the clinical information provided to patients about the progression and duration of illness and to highlight areas for future research. Searches were conducted using MEDLINE, CINAHL, PubMed, PsycINFO, and Web of Science for articles published between January 1966 and June 2018. Four longitudinal YOD cohort studies and their related substudies were identified. Alzheimer's disease (AD) was reported as the most frequently occurring YOD. The age at onset reported for two cohorts ranged from 53.8 to 60.2 years, depending on the dementia type. Three cohorts yielded substudies that focused on other aspects of YOD, including caregiver outcomes, neuropsychiatric symptoms, and psychotropic drug use. There were conflicting data regarding whether AD or frontotemporal dementia had the greatest rate of cognitive decline. The authors identified a restricted amount of clinical information that may be useful for patients and their families. Limitations included relatively short follow-up periods and types of dementia included. There was also a lack of information on longitudinal changes in neuropsychiatric symptoms and their relationship to biomarkers. These aspects are important considerations for future research, because they may yield information relevant to early diagnosis and disease progression, with improved clinical care for patients with YOD and their families. Streamlining data collection may also improve the ability to generalize results.","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"322-333"},"PeriodicalIF":2.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.19110238","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37926196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

"Top-Down" Mu-Opioid System Function in Humans: Mu-Opioid Receptors in Ventrolateral Prefrontal Cortex Mediate the Relationship Between Hedonic Tone and Executive Function in Major Depressive Disorder. 人类“自上而下”的mu -阿片系统功能:腹外侧前额叶皮层的mu -阿片受体介导重度抑郁症享乐张力和执行功能之间的关系。

IF 2.9

The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2017-01-01 Epub Date: 2017-04-17 DOI: 10.1176/appi.neuropsych.16090171

Sharee N Light, Linas A Bieliauskas, Jon-Kar Zubieta

引用次数: 17