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The Journal of Neuropsychiatry and Clinical Neurosciences最新文献

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Association between clinical measures and florbetapir F18 PET neuroimaging in mild or moderate Alzheimer's disease dementia. 临床措施与florbetapir F18 PET神经成像在轻度或中度阿尔茨海默病痴呆中的相关性
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.12120402
Michael M Witte, Paula Trzepacz, Michael Case, Peng Yu, Helen Hochstetler, Mitchell Quinlivan, Karen Sundell, David Henley
{"title":"Association between clinical measures and florbetapir F18 PET neuroimaging in mild or moderate Alzheimer's disease dementia.","authors":"Michael M Witte,&nbsp;Paula Trzepacz,&nbsp;Michael Case,&nbsp;Peng Yu,&nbsp;Helen Hochstetler,&nbsp;Mitchell Quinlivan,&nbsp;Karen Sundell,&nbsp;David Henley","doi":"10.1176/appi.neuropsych.12120402","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.12120402","url":null,"abstract":"<p><p>Clinical diagnosis of Alzheimer's disease (AD) is challenging, with 20% or more of patients misdiagnosed, even by expert clinicians. The authors conducted a retrospective, cross-sectional analysis comparing baseline neuropsychiatric and other clinical characteristics in 199 expert-diagnosed mild and moderate AD dementia patients participating in industry-sponsored clinical trials of an investigational therapy, where 18% lacked florbetapir positron emission tomography (PET) evidence of AD neuropathology. Significant differences were found only for cognition and ApoE ε4 status, but the large degree of score overlap would preclude using these measures to predict AD misdiagnosis. This study highlights the value of amyloid PET when evaluating patients with seemingly typical AD. </p>","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"214-20"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.12120402","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40301690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Kissing or "osculation" in frontotemporal dementia. 额颞叶痴呆中的接吻或“接触”。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13060139
Mario F Mendez, Jill S Shapira
{"title":"Kissing or \"osculation\" in frontotemporal dementia.","authors":"Mario F Mendez,&nbsp;Jill S Shapira","doi":"10.1176/appi.neuropsych.13060139","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13060139","url":null,"abstract":"<p><p>The authors investigated the neuropsychiatry of kissing in frontotemporal dementia. Among 15 patients, two had compulsive social kissing, bitemporal involvement, and Klüver-Bucy symptoms, and four pursued kissing with sexually disinhibited behavior. Future research should clarify the neuropsychiatric significance of kissing behavior. </p>","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"258-61"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13060139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32419583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Emperor Claudius' neuropsychiatric presentation: from tics to behavioral symptoms. 克劳迪斯皇帝的神经精神表现:从抽搐到行为症状。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13070163
Andrea E Cavanna, Andrea Nani, Michael R Trimble
{"title":"Emperor Claudius' neuropsychiatric presentation: from tics to behavioral symptoms.","authors":"Andrea E Cavanna,&nbsp;Andrea Nani,&nbsp;Michael R Trimble","doi":"10.1176/appi.neuropsych.13070163","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13070163","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E36-7"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13070163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Venlafaxine in treatment resistant obsessive-compulsive disorder. 文拉法辛治疗顽固性强迫症。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13080186
Janardhanan C Narayanaswamy, Biju Viswanath, Anish V Cherian, Suresh Bada Math, Y C Janardhan Reddy
{"title":"Venlafaxine in treatment resistant obsessive-compulsive disorder.","authors":"Janardhanan C Narayanaswamy,&nbsp;Biju Viswanath,&nbsp;Anish V Cherian,&nbsp;Suresh Bada Math,&nbsp;Y C Janardhan Reddy","doi":"10.1176/appi.neuropsych.13080186","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13080186","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E44-5"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13080186","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Psychotic episode in a patient with Alzheimer's dementia while shifting from the oral to patch form of rivastigmine. 阿尔茨海默氏痴呆症患者在从口服到贴片形式的利瓦斯汀转换时的精神病发作。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13090208
Shih-Chieh Ku, Chung-Chih Hsu, Hsin-An Chang, Yu-Chen Kao, Nian-Sheng Tzeng
{"title":"Psychotic episode in a patient with Alzheimer's dementia while shifting from the oral to patch form of rivastigmine.","authors":"Shih-Chieh Ku,&nbsp;Chung-Chih Hsu,&nbsp;Hsin-An Chang,&nbsp;Yu-Chen Kao,&nbsp;Nian-Sheng Tzeng","doi":"10.1176/appi.neuropsych.13090208","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13090208","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E51-2"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13090208","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Reversible tongue atrophy in acetylcholine receptor positive bulbar onset myasthenia gravis. 乙酰胆碱受体阳性的重症肌无力患者的可逆舌萎缩。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13080173
Mugundhan Krishnan, Nivas Balasubramaniyam
{"title":"Reversible tongue atrophy in acetylcholine receptor positive bulbar onset myasthenia gravis.","authors":"Mugundhan Krishnan,&nbsp;Nivas Balasubramaniyam","doi":"10.1176/appi.neuropsych.13080173","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13080173","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E56"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13080173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
"Undifferentiated schizophrenia" revisited. “未分化精神分裂症”再次出现。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13100227
Besa Ziso, Debbie Marsden, Sundus Alusi, Andrew J Larner
{"title":"\"Undifferentiated schizophrenia\" revisited.","authors":"Besa Ziso,&nbsp;Debbie Marsden,&nbsp;Sundus Alusi,&nbsp;Andrew J Larner","doi":"10.1176/appi.neuropsych.13100227","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13100227","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E62-3"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13100227","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
A case of acute-onset partial Kluver-Bucy syndrome in a patient with a history of traumatic brain injury. 有创伤性脑损伤史的患者急性发作部分性Kluver-Bucy综合征1例。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13060132
Nicholas Morcos, Hossam Guirgis
{"title":"A case of acute-onset partial Kluver-Bucy syndrome in a patient with a history of traumatic brain injury.","authors":"Nicholas Morcos,&nbsp;Hossam Guirgis","doi":"10.1176/appi.neuropsych.13060132","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13060132","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E10-1"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13060132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Marked reduction in serotonergic activity in a sexually aggressive adolescent male. 有性攻击性的青春期男性血清素活性明显降低。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13060138
Adarsh M Kumar, Mahendra Kumar, Benjamin B Lahey, Debra A Katz, Benny Fernandez, Jon A Shaw, Ana Campo, Charles B Nemeroff
{"title":"Marked reduction in serotonergic activity in a sexually aggressive adolescent male.","authors":"Adarsh M Kumar,&nbsp;Mahendra Kumar,&nbsp;Benjamin B Lahey,&nbsp;Debra A Katz,&nbsp;Benny Fernandez,&nbsp;Jon A Shaw,&nbsp;Ana Campo,&nbsp;Charles B Nemeroff","doi":"10.1176/appi.neuropsych.13060138","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13060138","url":null,"abstract":"<p><p>Serotonergic dysfunctions are implicated in conduct disorder, impulsivity, and aggression. Early adverse experiences increase the risk for these behaviors in adolescents. The authors investigated serotonergic activity in one adolescent male who experienced maternal abandonment and childhood abuse and exhibited severely aggressive sexual offenses. Platelet serotonin (5-HT) concentration, [14C]-5HT uptake kinetics, and plasma prolactin, cortisol response to D,L-fenfluramine (D,L-FEN) were measured. Results showed extremely low 5-HT concentration (2.9+/-0.7 ng/10⁸ platelets), [14C]-5HT uptake rate (0.5+/-0.04 mM/min/10⁷ platelets), undetectable Km and Vmax, and abnormally blunted prolactin, cortisol response to D,L-FEN. These abnormalities in this sexually aggressive adolescent may be a consequence of childhood abuse.</p>","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"262-70"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13060138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Electroconvulsive therapy and posttraumatic stress disorder: first experience with conversation-based reactivation of traumatic memory contents and subsequent ECT-mediated impairment of reconsolidation. 电休克疗法和创伤后应激障碍:创伤记忆内容对话再激活的首次体验和随后ect介导的再巩固损伤。
IF 2.9
The Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2014-01-01 DOI: 10.1176/appi.neuropsych.13070159
Maximilian Gahr, Carlos Schönfeldt-Lecuona, Manfred Spitzer, Heiko Graf
{"title":"Electroconvulsive therapy and posttraumatic stress disorder: first experience with conversation-based reactivation of traumatic memory contents and subsequent ECT-mediated impairment of reconsolidation.","authors":"Maximilian Gahr,&nbsp;Carlos Schönfeldt-Lecuona,&nbsp;Manfred Spitzer,&nbsp;Heiko Graf","doi":"10.1176/appi.neuropsych.13070159","DOIUrl":"https://doi.org/10.1176/appi.neuropsych.13070159","url":null,"abstract":"","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"E38-9"},"PeriodicalIF":2.9,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13070159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32561242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
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