Research in Developmental Disabilities最新文献

{"title":"Development of fluid intelligence in children and adolescents with cerebral palsy: A cross-sectional study","authors":"Daiki Asano ,&nbsp;Masaki Takeda ,&nbsp;Hirotaka Gima ,&nbsp;Satoshi Nobusako","doi":"10.1016/j.ridd.2025.104928","DOIUrl":"10.1016/j.ridd.2025.104928","url":null,"abstract":"<div><h3>Background</h3><div>Cerebral palsy (CP) often presents alongside cognitive developmental delays and motor impairments. This study aimed to identify the function most closely linked to the development of fluid intelligence in individuals with CP, and to estimate the point at which the fluid intelligence of children with CP diverges from that of typically developing (TD) children.</div></div><div><h3>Methods and procedures</h3><div>Raven’s Coloured Progressive Matrices (RCPM) were used to evaluate the fluid intelligence of participants. Fifty-one participants with CP aged 4–18 years and 33 TD children aged 3–9 years were included in this study and underwent RCPM testing. The severity of CP was assessed using the Gross Motor Function Classification System (GMFCS), Manual Ability Classification System (MACS) and Communication Function Classification System (CFCS).</div></div><div><h3>Results</h3><div>Multiple regression analysis demonstrated that within the three distinct functional levels, MACS was a significant predictor of fluid intelligence in children with CP (β = – 0.29, p &lt; 0.05). Significant disparities in the development of fluid intelligence between the CP and TD groups emerge after 57.6 months of age.</div></div><div><h3>Conclusions and implications</h3><div>The findings offer valuable insights into timely and functionally targeted interventions to prevent cognitive stagnation.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"158 ","pages":"Article 104928"},"PeriodicalIF":2.9,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and psychometric properties of the Italian little developmental coordination disorder questionnaire (LDCDQ-IT)","authors":"Barbara Caravale ,&nbsp;Anna Di Norcia ,&nbsp;Arianna Boiani ,&nbsp;Maria Teresa Giannini ,&nbsp;Silvia Baldi ,&nbsp;Lucilla Ravà ,&nbsp;Carlo Di Brina ,&nbsp;Tanya Rihtman","doi":"10.1016/j.ridd.2025.104923","DOIUrl":"10.1016/j.ridd.2025.104923","url":null,"abstract":"<div><h3>Background</h3><div>Early identification of Developmental Coordination Disorder (DCD) in children is fundamental to provide the best chance of improving their outcomes. The Little Developmental Coordination Disorder Questionnaire (LDCDQ) is a screening tool to identify preschool children who may warrant a diagnosis of DCD.</div></div><div><h3>Aims</h3><div>This study conducted a transcultural translation and adaptation of the Italian version of the Little Developmental Coordination Disorder Questionnaire (LDCDQ-IT) and evaluated the psychometric properties of the tool, establishing also the optimal cut-off scores.</div></div><div><h3>Methods and procedures</h3><div>Parents/carers of 3- and 4-year-old Italian preschoolers completed the LDCDQ-IT (n = 352 typically developing children; n = 24 children at risk for motor coordination problems). One sub-sample (n = 52) completed the LDCDQ-IT a second time; another sub-sample (n = 90) was assessed using the Movement Assessment Battery for Children (MABC-2).</div></div><div><h3>Results</h3><div>The LDCDQ-IT showed high internal consistency (α=0.96) and good test–retest reliability. Children’s age and gender did not influence total scores. Correlations obtained between the LDCDQ-IT and MABC-2 total scores (r = 0.52, p &lt; 0.001) suggest concurrent validity of the LDCDQ-IT. Using a cut-off score of ≤ 65, overall sensitivity and specificity were 79 % and 75 % respectively. Conclusions and implications: The LDCDQ-IT demonstrates promising psychometric properties, making it a useful tool for the early identification of DCD.</div></div><div><h3>What this paper adds?</h3><div>This study provides valuable insights into the psychometric properties and cut-off point for the Italian Little Developmental Coordination Disorder Questionnaire (LDCDQ-IT), a screening tool for identifying potential motor coordination problems in 3- and 4-year-old children. We observed good evidence of reliability, concurrent, and discriminative validity, proving that it may be a helpful questionnaire for assessing daily motor skills.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"158 ","pages":"Article 104923"},"PeriodicalIF":2.9,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of executive functions in preschool children with autism spectrum disorder: A short narrative review","authors":"Emanuela Petrolo ,&nbsp;Silvia Guerrera ,&nbsp;Maria Grazia Logrieco ,&nbsp;Laura Casula ,&nbsp;Stefano Vicari ,&nbsp;Giovanni Valeri","doi":"10.1016/j.ridd.2024.104905","DOIUrl":"10.1016/j.ridd.2024.104905","url":null,"abstract":"<div><div>Atypical executive functions (EFs) are well-documented in individuals with autism spectrum disorders (ASD) across all ages. However, most research focuses on EFs impairments in school-aged children and older, with less attention to preschool children. Understanding EF deficits in this age group is challenging and underexplored due to limited studies and measurement difficulties. The current short narrative review's aim is to provide an update on the knowledge on EFs in preschool children with ASD and their association with ASD symptoms. Despite varied results, recent research suggests early EF difficulties, potentially linked to greater impairments in social skills and externalizing behaviors. This suggests the importance of implementing early interventions that take into account the enhancement of these areas from an early age. Further investigation in this age group could enhance our understanding of ASD.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104905"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated segmentation of child-clinician speech in naturalistic clinical contexts","authors":"Giulio Bertamini ,&nbsp;Cesare Furlanello ,&nbsp;Mohamed Chetouani ,&nbsp;David Cohen ,&nbsp;Paola Venuti","doi":"10.1016/j.ridd.2024.104906","DOIUrl":"10.1016/j.ridd.2024.104906","url":null,"abstract":"<div><h3>Background</h3><div>Computational approaches hold significant promise for enhancing diagnosis and therapy in child and adolescent clinical practice. Clinical procedures heavily depend n vocal exchanges and interpersonal dynamics conveyed through speech. Research highlights the importance of investigating acoustic features and dyadic interactions during child development. However, observational methods are labor-intensive, time-consuming, and suffer from limited objectivity and quantification, hindering translation to everyday care.</div></div><div><h3>Aims</h3><div>We propose a novel AI-based system for fully automatic acoustic segmentation of clinical sessions with autistic preschool children.</div></div><div><h3>Methods and procedures</h3><div>We focused on naturalistic and unconstrained clinical contexts, which are characterized by background noise and data scarcity. Our approach addresses key challenges in the field while remaining non-invasive. We carefully evaluated model performance and flexibility in diverse, challenging conditions by means of domain alignment.</div></div><div><h3>Outcomes and results</h3><div>Results demonstrated promising outcomes in voice activity detection and speaker diarization. Notably, minimal annotation efforts —just 30 seconds of target data— significantly improved model performance across all tested conditions. Our models exhibit satisfying predictive performance and flexibility for deployment in everyday settings.</div></div><div><h3>Conclusions and implications</h3><div>Automating data annotation in real-world clinical scenarios can enable the widespread exploitation of advanced computational methods for downstream modeling, fostering precision approaches that bridge research and clinical practice.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104906"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Active Support on the quality of life and well-being of people with moderate to mild intellectual disabilities","authors":"Aniek van Herwaarden ,&nbsp;Nienke C. Peters-Scheffer ,&nbsp;Monique Mulders ,&nbsp;Vaso Totsika ,&nbsp;Robert Didden","doi":"10.1016/j.ridd.2025.104925","DOIUrl":"10.1016/j.ridd.2025.104925","url":null,"abstract":"<div><div>Active Support is a support model designed to enhance quality of life through activity engagement in people with intellectual disabilities. The aim of the current study was to investigate whether implementation of Active Support affected quality of life, well-being, and activity engagement of residents with mild to moderate intellectual disabilities, using a cluster randomised controlled design. Fourteen services were recruited, and Active Support was implemented after conducting baseline assessments. Residents in both the intervention group (<em>n</em> = 47) and the control group (<em>n</em> = 38) reported on their Quality of Life, eudaimonic well-being, and activity engagement at pretest and at follow-up 9 months after pretest. Level of Active Support implementation was monitored by observing the quality of support and practice leadership. Active Support had a significant effect on independence and well-being, two subscales of quality of life. Residents in the intervention group showed a significantly larger increase on social activity engagement compared to the control group. There were no significant interaction terms for other resident outcomes. For the intervention group, there was a significant increase in quality of support. Findings indicated significant impact on some aspects of quality of life, though not all. Suggestions for future research are therefore discussed.</div></div><div><h3>What this paper adds?</h3><div>Active Support is a support model that is increasingly adopted across several countries. Although there is considerable evidence that Active Support increases activity engagement for people with an intellectual disability, there are very few randomised controlled trials to test effectiveness, and the impact of Active Support on overall quality of life has never been examined. To address these gaps, the current study therefore evaluated the impact of Active Support on quality of life and resident well-being using a randomised controlled trial. This evaluation of Active Support contributes to the existing body of knowledge on the support model, strengthening its evidence base for people with moderate to mild intellectual disability.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104925"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empowering lives: How deinstitutionalization and community living improve the quality of life of individuals with intellectual and developmental disabilities","authors":"Patricia Navas ,&nbsp;Víctor B. Arias ,&nbsp;Eva Vicente ,&nbsp;Laura Esteban ,&nbsp;Verónica M. Guillén ,&nbsp;Natalia Alvarado ,&nbsp;Inés Heras ,&nbsp;Paula Rumoroso ,&nbsp;Laura García-Domínguez ,&nbsp;Miguel Ángel Verdugo","doi":"10.1016/j.ridd.2024.104909","DOIUrl":"10.1016/j.ridd.2024.104909","url":null,"abstract":"<div><h3>Background</h3><div>The number of people with intellectual and developmental disabilities (IDD) living in residential settings has not changed substantially in recent years in Spain. To change this situation the project “My House: A Life in the Community” aims to promote the transition of individuals with IDD and high support needs into community settings.</div></div><div><h3>Aims</h3><div>This paper deepens the understanding of the underlying mechanisms responsible for the changes observed in the process of deinstitutionalization.</div></div><div><h3>Methods</h3><div>A longitudinal study was designed to evaluate the quality of life of individuals with IDD (<em>n</em> = 90) across different environments at two distinct time points: when they were living in an institution and nine months after transitioning to a community-based setting. A comparison group (<em>n</em> = 72) consisting of individuals who remained institutionalized was included to carry out intergroup comparisons. <em>T</em>-tests were used to estimate mean differences both between and within groups. Longitudinal path models were used to investigate the processes underlying the relationships between variables.</div></div><div><h3>Results</h3><div>After transition, movers obtained significantly higher mean scores on all variables with large or very large effect sizes. However, simply moving to a different place was not the factor responsible for the observed improvements: positive changes in quality of life require the constant availability of opportunities to support decision making.</div></div><div><h3>Implications</h3><div>deinstitutionalization will only lead to improvements in quality of life if it favors people’s control over their lives. Community living should therefore be understood not as an autonomous life but as a chosen one.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104909"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of sensory processing changes in children with developmental coordination disorder: A systematic review","authors":"Meyene Duque Weber ,&nbsp;Tatiane Targino Gomes Draghi ,&nbsp;Ana Clara Silva Maia ,&nbsp;John Cairney ,&nbsp;Jorge Lopes Cavalcante-Neto ,&nbsp;Eloisa Tudella","doi":"10.1016/j.ridd.2025.104917","DOIUrl":"10.1016/j.ridd.2025.104917","url":null,"abstract":"<div><h3>Background</h3><div>Sensory processing difficulties are common in neurodevelopment conditions, such as developmental coordination disorder (DCD), and can significantly impact daily living activities.</div></div><div><h3>Aims</h3><div>To systematically review the literature to (1) synthesize the characteristics (sections and patterns) of sensory processing alterations in children with developmental coordination disorder (DCD), (2) compare these characteristics with those of children with typical development or associated comorbidities, and (3) identify which characteristics may be present from early childhood.</div></div><div><h3>Methods</h3><div>This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was submitted and registered in PROSPERO. The literature search was conducted in the MEDLINE/PubMed, Web of Science, Scopul, SciELO, LILACS, ERIC, and EMBASE databases. Original studies that evaluated the sensory processing of children with DCD aged 3–12 years using standardized instruments were included.</div></div><div><h3>Results</h3><div>A total of 2609 studies were retrieved from databases. Of these, five studies that identified sensory processing alterations in children with DCD were included. The most affected sensory characteristics were touch and balance and motion sections, and the avoider pattern, which may present behaviors observed in early childhood. The methodological quality of studies ranged from moderate to high, whereas effect sizes ranged from small to moderate.</div></div><div><h3>Conclusions</h3><div>This systematic review identified that children with DCD or probable DCD presented sensory processing alterations. Further studies with high methodological quality are needed to recommend the sensory processing characteristics impacting the early identification of DCD.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104917"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “The relation between visual functions, functional vision, and bimanual function in children with unilateral cerebral palsy” [Research in Developmental Disabilities 152 (2024) 104792]","authors":"Monica Crotti ,&nbsp;Els Ortibus ,&nbsp;Nofar Ben Itzhak ,&nbsp;Lize Kleeren ,&nbsp;Lisa Decraene ,&nbsp;Nicolas Leenaerts ,&nbsp;Hilde Feys ,&nbsp;Lisa Mailleux","doi":"10.1016/j.ridd.2025.104920","DOIUrl":"10.1016/j.ridd.2025.104920","url":null,"abstract":"","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104920"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transfer of motor and strategy learning in children with Developmental Coordination Disorder (DCD): A scoping review","authors":"Laureen Josseron ,&nbsp;Wilfried Thierry Mombo ,&nbsp;Mélanie Maggiacomo ,&nbsp;Caroline Jolly ,&nbsp;Jérôme Clerc","doi":"10.1016/j.ridd.2024.104908","DOIUrl":"10.1016/j.ridd.2024.104908","url":null,"abstract":"<div><div>Developmental coordination disorder (DCD) is a developmental disorder that affects the learning and execution of motor skills. Little is known about their ability to transfer their learning, i.e. to adapt prior knowledge to new tasks (Hattie &amp; Donoghue, 2016). This is an important issue in these children, both to better understand how they can adapt initial learning to new tasks, and to develop interventions that will enable them to transfer their knowledge into their daily lives. The aim of this scoping review is to assess the body and nature of the existing literature on transfer of learning in children with DCD. After a search in 4 databases, 58 publications meeting the inclusion criteria were included. Among the studies, 18 aimed at measuring transfer, other can be interpreted as measuring transfer of learning even if transfer is not explicitly mentioned by the authors. The results show that children with DCD seem to have difficulty transferring their motor learning when the transfer tasks are far from the trained tasks but seem able to transfer their learning when the transfer tasks remain close, however they can transfer cognitive strategies to more distant transfer tasks. Future research is needed to systematically assess different aspects of transfer, with the aim of proposing effective interventions for children with DCD.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104908"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of comorbid allergic diseases on attention-deficit hyperactivity disorder symptoms and sleep: A cross-sectional study","authors":"Zhang Panpan ,&nbsp;Liu Yang ,&nbsp;Ma Tao ,&nbsp;Tian Chong ,&nbsp;Cao Fan ,&nbsp;Sun Hao ,&nbsp;Xiao Xuwu","doi":"10.1016/j.ridd.2024.104907","DOIUrl":"10.1016/j.ridd.2024.104907","url":null,"abstract":"<div><h3>Introduction</h3><div>Recent studies have shown a close relationship between attention-deficit hyperactivity disorder (ADHD) and allergic diseases in children. Regrettably, few studies have investigated the effect of comorbid allergies on ADHD symptoms and sleep, in particular, it is unclear whether comorbid allergic conditions further exacerbate sleep problems in children with ADHD.</div></div><div><h3>Objective</h3><div>To investigate the effect of comorbid allergic on symptoms and sleep in children with ADHD.</div></div><div><h3>Methods</h3><div>This was a cross-sectional study, 222 ADHD children (aged 6–14 years) were enrolled in, of whom 93 had allergic diseases and 129 without allergic diseases. Collected all ADHD symptom severity and functional impairment scales, including: Swanson, Nolan and Pelham (SNAP) scale, Integrated Visual and Auditory Continuous Performance Test (IVA-CPT), Conners Parents Symptom questionnaire (PSQ) and Weiss Functional Impairment Rating Scale-Parent Form (WFIRS-P). Every guardian of children diagnosed with ADHD is required to complete the Children’s Sleep Habits Questionnaire (CSHQ).</div></div><div><h3>Results</h3><div>Compared to ADHD children without allergic diseases, we observed significantly higher hyperactivity and impulsivity scores on the SNAP-IV, higher hyperactivity index and impulsivity index on the PSQ, and higher risky activities on the WFIRS-P in ADHD children with comorbid allergic diseases (all <em>p</em> &lt; 0.05). CSHQ total score and sleep disordered breathing were particularly prominent in ADHD children with comorbid allergic diseases (all <em>p</em> &lt; 0.05), and changes in CSHQ correlate with ADHD symptoms and functional impairment. Further analyses revealed that ADHD symptoms and sleep did not worsen with increasing number of comorbid allergic diseases (all <em>p</em> &gt; 0.05). The primary influence on ADHD symptoms and sleep was the type of allergic diseases, where food allergies predominantly influence ADHD symptoms, including attention deficit disorder and hyperactivity disorder (all <em>p</em> &lt; 0.05); allergic rhinitis notably impacts parasomnias, sleep disordered breathing (all <em>p</em> &lt; 0.05); and allergic asthma significantly affects sleep anxiety, daytime sleepiness, and sleep disordered breathing in children with ADHD (all <em>p</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>The presence of comorbid allergic diseases affects both the hyperactivity and impulsivity symptoms of ADHD and sleep disordered breathing, predominantly influenced by the type of the allergic diseases.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"157 ","pages":"Article 104907"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}