Animal Health Research Reviews最新文献

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Editorial: Systematic reviews reveal a need for more, better data to inform antimicrobial stewardship practices in animal agriculture. 社论:系统审查表明,需要更多、更好的数据来为动物农业中的抗微生物药物管理实践提供信息。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000240
Jan M Sargeant, Annette M O'Connor, Charlotte B Winder
{"title":"Editorial: Systematic reviews reveal a need for more, better data to inform antimicrobial stewardship practices in animal agriculture.","authors":"Jan M Sargeant,&nbsp;Annette M O'Connor,&nbsp;Charlotte B Winder","doi":"10.1017/S1466252319000240","DOIUrl":"https://doi.org/10.1017/S1466252319000240","url":null,"abstract":"<p><p>This editorial summarizes the key observations from a special issue of Animal Health Research Reviews comprising 14 articles related to the efficacy of antimicrobial and non-antimicrobial approaches to reduce disease in beef, dairy cattle, swine, and broiler chickens. The articles used evidence-based methods, including scoping reviews, systematic reviews, meta-analyses, and network meta-analyses. Despite finding evidence of efficacy for some of the interventions examined, across the body of research, there was a lack of replication and inconsistency in outcomes among the included trials, and concerns related to completeness of reporting and trial design and execution. There is an urgent need for more and better data to inform antimicrobial stewardship practices in animal agriculture.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"103-105"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Comparative efficacy of teat sealants given prepartum for prevention of intramammary infections and clinical mastitis: a systematic review and network meta-analysis. 乳封剂预防乳内感染和临床乳腺炎的比较疗效:一项系统综述和网络荟萃分析。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000276
C B Winder, J M Sargeant, D Hu, C Wang, D F Kelton, S J Leblanc, T F Duffield, J Glanville, H Wood, K J Churchill, J Dunn, M D Bergevin, K Dawkins, S Meadows, B Deb, M Reist, C Moody, A M O'Connor
{"title":"Comparative efficacy of teat sealants given prepartum for prevention of intramammary infections and clinical mastitis: a systematic review and network meta-analysis.","authors":"C B Winder,&nbsp;J M Sargeant,&nbsp;D Hu,&nbsp;C Wang,&nbsp;D F Kelton,&nbsp;S J Leblanc,&nbsp;T F Duffield,&nbsp;J Glanville,&nbsp;H Wood,&nbsp;K J Churchill,&nbsp;J Dunn,&nbsp;M D Bergevin,&nbsp;K Dawkins,&nbsp;S Meadows,&nbsp;B Deb,&nbsp;M Reist,&nbsp;C Moody,&nbsp;A M O'Connor","doi":"10.1017/S1466252319000276","DOIUrl":"https://doi.org/10.1017/S1466252319000276","url":null,"abstract":"<p><p>A systematic review and network meta-analysis were conducted to assess the relative efficacy of internal or external teat sealants given at dry-off in dairy cattle. Controlled trials were eligible if they assessed the use of internal or external teat sealants, with or without concurrent antimicrobial therapy, compared to no treatment or an alternative treatment, and measured one or more of the following outcomes: incidence of intramammary infection (IMI) at calving, IMI during the first 30 days in milk (DIM), or clinical mastitis during the first 30 DIM. Risk of bias was based on the Cochrane Risk of Bias 2.0 tool with modified signaling questions. From 2280 initially identified records, 32 trials had data extracted for one or more outcomes. Network meta-analysis was conducted for IMI at calving. Use of an internal teat sealant (bismuth subnitrate) significantly reduced the risk of new IMI at calving compared to non-treated controls (RR = 0.36, 95% CI 0.25-0.72). For comparisons between antimicrobial and teat sealant groups, concerns regarding precision were seen. Synthesis of the primary research identified important challenges related to the comparability of outcomes, replication and connection of interventions, and quality of reporting of study conduct.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"182-198"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000276","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
AHR volume 20 issue 2 Cover and Front matter AHR第20卷第2期封面和封面
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/s1466252320000055
{"title":"AHR volume 20 issue 2 Cover and Front matter","authors":"","doi":"10.1017/s1466252320000055","DOIUrl":"https://doi.org/10.1017/s1466252320000055","url":null,"abstract":"","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 1","pages":"f1 - f2"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/s1466252320000055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45502019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative efficacy of antimicrobial treatments in dairy cows at dry-off to prevent new intramammary infections during the dry period or clinical mastitis during early lactation: a systematic review and network meta-analysis. 奶牛干乳期抗菌治疗预防干乳期新发乳内感染或泌乳早期临床乳腺炎的比较效果:一项系统综述和网络荟萃分析
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000239
C B Winder, J M Sargeant, D Hu, C Wang, D F Kelton, S J Leblanc, T F Duffield, J Glanville, H Wood, K J Churchill, J Dunn, M D Bergevin, K Dawkins, S Meadows, B Deb, M Reist, C Moody, A M O'Connor
{"title":"Comparative efficacy of antimicrobial treatments in dairy cows at dry-off to prevent new intramammary infections during the dry period or clinical mastitis during early lactation: a systematic review and network meta-analysis.","authors":"C B Winder,&nbsp;J M Sargeant,&nbsp;D Hu,&nbsp;C Wang,&nbsp;D F Kelton,&nbsp;S J Leblanc,&nbsp;T F Duffield,&nbsp;J Glanville,&nbsp;H Wood,&nbsp;K J Churchill,&nbsp;J Dunn,&nbsp;M D Bergevin,&nbsp;K Dawkins,&nbsp;S Meadows,&nbsp;B Deb,&nbsp;M Reist,&nbsp;C Moody,&nbsp;A M O'Connor","doi":"10.1017/S1466252319000239","DOIUrl":"https://doi.org/10.1017/S1466252319000239","url":null,"abstract":"<p><p>A systematic review and network meta-analysis were conducted to assess the relative efficacy of antimicrobial therapy given to dairy cows at dry-off. Eligible studies were controlled trials assessing the use of antimicrobials compared to no treatment or an alternative treatment, and assessed one or more of the following outcomes: incidence of intramammary infection (IMI) at calving, incidence of IMI during the first 30 days in milk (DIM), or incidence of clinical mastitis during the first 30 DIM. Databases and conference proceedings were searched for relevant articles. The potential for bias was assessed using the Cochrane Risk of Bias 2.0 algorithm. From 3480 initially identified records, 45 trials had data extracted for one or more outcomes. Network meta-analysis was conducted for IMI at calving. The use of cephalosporins, cloxacillin, or penicillin with aminoglycoside significantly reduced the risk of new IMI at calving compared to non-treated controls (cephalosporins, RR = 0.37, 95% CI 0.23-0.65; cloxacillin, RR = 0.55, 95% CI 0.38-0.79; penicillin with aminoglycoside, RR = 0.42, 95% CI 0.26-0.72). Synthesis revealed challenges with a comparability of outcomes, replication of interventions, definitions of outcomes, and quality of reporting. The use of reporting guidelines, replication among interventions, and standardization of outcome definitions would increase the utility of primary research in this area.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"199-216"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000239","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Efficacy of bacterial vaccines to prevent respiratory disease in swine: a systematic review and network meta-analysis. 细菌疫苗预防猪呼吸道疾病的有效性:系统综述和网络荟萃分析。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000173
Jan M Sargeant, Bhumika Deb, Michele D Bergevin, Katheryn Churchill, Kaitlyn Dawkins, Jennifer Dunn, Dapeng Hu, Carly Moody, Annette M O'Connor, Terri L O'Sullivan, Mark Reist, Chong Wang, Barbara Wilhelm, Charlotte B Winder
{"title":"Efficacy of bacterial vaccines to prevent respiratory disease in swine: a systematic review and network meta-analysis.","authors":"Jan M Sargeant,&nbsp;Bhumika Deb,&nbsp;Michele D Bergevin,&nbsp;Katheryn Churchill,&nbsp;Kaitlyn Dawkins,&nbsp;Jennifer Dunn,&nbsp;Dapeng Hu,&nbsp;Carly Moody,&nbsp;Annette M O'Connor,&nbsp;Terri L O'Sullivan,&nbsp;Mark Reist,&nbsp;Chong Wang,&nbsp;Barbara Wilhelm,&nbsp;Charlotte B Winder","doi":"10.1017/S1466252319000173","DOIUrl":"https://doi.org/10.1017/S1466252319000173","url":null,"abstract":"<p><p>A systematic review and network meta-analysis (MA) was conducted to address the question, 'What is the efficacy of bacterial vaccines to prevent respiratory disease in swine?' Four electronic databases and the grey literature were searched to identify clinical trials in healthy swine where at least one intervention arm was a commercially available vaccine for one or more bacterial pathogens associated with respiratory disease in swine, including Mycoplasma hyopneumoniae, Actinobacillus pleuropneumonia, Actinobacillus suis, Bordetella bronchiseptica, Pasteurella multocida, Stretococcus suis, Haemophils parasuis, and Mycoplasma hyorhinis. To be eligible, trials had to measure at least one of the following outcomes: incidence of clinical morbidity, mortality, lung lesions, or total antibiotic use. There were 179 eligible trials identified in 146 publications. Network MA was undertaken for morbidity, mortality, and the presence or absence of non-specific lung lesions. However, there was not a sufficient body of research evaluating the same interventions and outcomes to allow a meaningful synthesis of the comparative efficacy of the vaccines. To build this body of research, additional rigor in trial design and analysis, and detailed reporting of trial methods and results are warranted.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"274-290"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
The efficacy of antibiotics to control colibacillosis in broiler poultry: a systematic review. 抗生素控制肉鸡大肠杆菌病的疗效:系统综述。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000264
Jan M Sargeant, Michele D Bergevin, Katheryn Churchill, Kaitlyn Dawkins, Bhumika Deb, Jennifer Dunn, Catherine M Logue, Anastasia Novy, Annette M O'Connor, Mark Reist, Charlotte B Winder
{"title":"The efficacy of antibiotics to control colibacillosis in broiler poultry: a systematic review.","authors":"Jan M Sargeant,&nbsp;Michele D Bergevin,&nbsp;Katheryn Churchill,&nbsp;Kaitlyn Dawkins,&nbsp;Bhumika Deb,&nbsp;Jennifer Dunn,&nbsp;Catherine M Logue,&nbsp;Anastasia Novy,&nbsp;Annette M O'Connor,&nbsp;Mark Reist,&nbsp;Charlotte B Winder","doi":"10.1017/S1466252319000264","DOIUrl":"https://doi.org/10.1017/S1466252319000264","url":null,"abstract":"<p><p>The objective of this systematic review was to evaluate the efficacy of antibiotics to prevent or control colibacillosis in broilers. Studies found eligible were conducted controlled trials in broilers that evaluated an antibiotic intervention, with at least one of the following outcomes: mortality, feed conversion ratio (FCR), condemnations at slaughter, or total antibiotic use. Four electronic databases plus the gray literature were searched. Abstracts were screened for eligibility and data were extracted from eligible trials. Risk of bias was evaluated.Seven trials reported eligible outcomes in a format that allowed data extraction; all reported results for FCR and one also reported mortality. Due to the heterogeneity in the interventions and outcomes evaluated, it was not feasible to conduct meta-analysis.Qualitatively, for FCR, comparisons between an antibiotic and an alternative product did not show a significant benefit for either. Some of the comparisons between an antibiotic and a no-treatment placebo showed a numerical benefit to antibiotics, but with wide confidence intervals. The risk-of-bias assessment revealed concerns with reporting of key trial features.The results of this review do not provide compelling evidence for or against the efficacy of antibiotics for the control of colibacillosis.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"263-273"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000264","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
A systematic review and network meta-analysis of injectable antibiotic options for the control of bovine respiratory disease in the first 45 days post arrival at the feedlot. 在到达饲养场后的头45天内用于控制牛呼吸道疾病的注射抗生素选择的系统回顾和网络荟萃分析。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252320000031
A M O'Connor, D Hu, S C Totton, N Scott, C B Winder, B Wang, C Wang, J Glanville, H Wood, B White, R Larson, C Waldner, J M Sargeant
{"title":"A systematic review and network meta-analysis of injectable antibiotic options for the control of bovine respiratory disease in the first 45 days post arrival at the feedlot.","authors":"A M O'Connor,&nbsp;D Hu,&nbsp;S C Totton,&nbsp;N Scott,&nbsp;C B Winder,&nbsp;B Wang,&nbsp;C Wang,&nbsp;J Glanville,&nbsp;H Wood,&nbsp;B White,&nbsp;R Larson,&nbsp;C Waldner,&nbsp;J M Sargeant","doi":"10.1017/S1466252320000031","DOIUrl":"https://doi.org/10.1017/S1466252320000031","url":null,"abstract":"<p><p>We conducted a systematic review and network meta-analysis to determine the comparative efficacy of antibiotics used to control bovine respiratory disease (BRD) in beef cattle on feedlots. The information sources for the review were: MEDLINE®, MEDLINE In-Process and MEDLINE® Daily, AGRICOLA, Epub Ahead of Print, Cambridge Agricultural and Biological Index, Science Citation Index, Conference Proceedings Citation Index - Science, the Proceedings of the American Association of Bovine Practitioners, World Buiatrics Conference, and the United States Food and Drug Administration Freedom of Information New Animal Drug Applications summaries. The eligible population was weaned beef cattle raised in intensive systems. The interventions of interest were injectable antibiotics used at the time the cattle arrived at the feedlot. The outcome of interest was the diagnosis of BRD within 45 days of arrival at the feedlot. The network meta-analysis included data from 46 studies and 167 study arms identified in the review. The results suggest that macrolides are the most effective antibiotics for the reduction of BRD incidence. Injectable oxytetracycline effectively controlled BRD compared with no antibiotics; however, it was less effective than macrolide treatment. Because oxytetracycline is already commonly used to prevent, control, and treat BRD in groups of feedlot cattle, the use of injectable oxytetracycline for BRD control might have advantages from an antibiotic stewardship perspective.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"163-181"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252320000031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Comparative efficacy of blanket versus selective dry-cow therapy: a systematic review and pairwise meta-analysis. 毛毯疗法与选择性干牛疗法的疗效比较:系统回顾和两两荟萃分析。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000306
C B Winder, J M Sargeant, D F Kelton, S J Leblanc, T F Duffield, J Glanville, H Wood, K J Churchill, J Dunn, M D Bergevin, K Dawkins, S Meadows, A M O'Connor
{"title":"Comparative efficacy of blanket versus selective dry-cow therapy: a systematic review and pairwise meta-analysis.","authors":"C B Winder,&nbsp;J M Sargeant,&nbsp;D F Kelton,&nbsp;S J Leblanc,&nbsp;T F Duffield,&nbsp;J Glanville,&nbsp;H Wood,&nbsp;K J Churchill,&nbsp;J Dunn,&nbsp;M D Bergevin,&nbsp;K Dawkins,&nbsp;S Meadows,&nbsp;A M O'Connor","doi":"10.1017/S1466252319000306","DOIUrl":"https://doi.org/10.1017/S1466252319000306","url":null,"abstract":"<p><p>A systematic review and meta-analysis were conducted to determine the efficacy of selective dry-cow antimicrobial therapy compared to blanket therapy (all quarters/all cows). Controlled trials were eligible if any of the following were assessed: incidence of clinical mastitis during the first 30 DIM, frequency of intramammary infection (IMI) at calving, or frequency of IMI during the first 30 DIM. From 3480 identified records, nine trials were data extracted for IMI at calving. There was an insufficient number of trials to conduct meta-analysis for the other outcomes. Risk of IMI at calving in selectively treated cows was higher than blanket therapy (RR = 1.34, 95% CI = 1.13, 1.16), but substantial heterogeneity was present (I2 = 58%). Subgroup analysis showed that, for trials using internal teat sealants, there was no difference in IMI risk at calving between groups, and no heterogeneity was present. For trials not using internal teat sealants, there was an increased risk in cows assigned to a selective dry-cow therapy protocol, compared to blanket treatment, with substantial heterogeneity in this subgroup. However, the small number of trials and heterogeneity in the subgroup without internal teat sealants suggests that the relative risk between treatments may differ from the determined point estimates based on other unmeasured factors.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"217-228"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Comparative efficacy of antimicrobials for treatment of clinical mastitis in lactating dairy cattle: a systematic review and network meta-analysis. 抗微生物药物治疗泌乳奶牛临床乳腺炎的比较疗效:系统综述和网络荟萃分析。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000318
C B Winder, J M Sargeant, D Hu, C Wang, D F Kelton, M A Godkin, K J Churchill, A M O'Connor
{"title":"Comparative efficacy of antimicrobials for treatment of clinical mastitis in lactating dairy cattle: a systematic review and network meta-analysis.","authors":"C B Winder,&nbsp;J M Sargeant,&nbsp;D Hu,&nbsp;C Wang,&nbsp;D F Kelton,&nbsp;M A Godkin,&nbsp;K J Churchill,&nbsp;A M O'Connor","doi":"10.1017/S1466252319000318","DOIUrl":"https://doi.org/10.1017/S1466252319000318","url":null,"abstract":"<p><p>A systematic review and network meta-analysis were conducted to assess the relative efficacy of antimicrobial therapy for clinical mastitis in lactating dairy cattle. Controlled trials in lactating dairy cattle with natural disease exposure were eligible if they compared an antimicrobial treatment to a non-treated control, placebo, or a different antimicrobial, for the treatment of clinical mastitis, and assessed clinical or bacteriologic cure. Potential for bias was assessed using a modified Cochrane Risk of Bias 2.0 tool. From 14775 initially identified records, 54 trials were assessed as eligible. Networks were established for bacteriologic cure by bacterial species group, and clinical cure. Disparate networks among bacteriologic cures precluded meta-analysis. Network meta-analysis was conducted for trials assessing clinical cure, but lack of precision of point estimates resulted in wide credibility intervals for all treatments, with no definitive conclusions regarding relative efficacy. Consideration of network geometry can inform future research to increase the utility of current and previous work. Replication of intervention arms and consideration of connection to existing networks would improve the future ability to determine relative efficacy. Challenges in the evaluation of bias in primary research stemmed from a lack of reporting. Consideration of reporting guidelines would also improve the utility of future research.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"229-246"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000318","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37663387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Systematic reviews and meta-analyses in animal health, performance, and on-farm food safety: a scoping review. 动物健康、生产性能和农场食品安全的系统评价和荟萃分析:范围审查。
IF 2.5 2区 农林科学
Animal Health Research Reviews Pub Date : 2019-12-01 DOI: 10.1017/S1466252319000197
Rachael Vriezen, Jan M Sargeant, Ellen Vriezen, Mark Reist, Charlotte B Winder, Annette M O'Connor
{"title":"Systematic reviews and meta-analyses in animal health, performance, and on-farm food safety: a scoping review.","authors":"Rachael Vriezen,&nbsp;Jan M Sargeant,&nbsp;Ellen Vriezen,&nbsp;Mark Reist,&nbsp;Charlotte B Winder,&nbsp;Annette M O'Connor","doi":"10.1017/S1466252319000197","DOIUrl":"https://doi.org/10.1017/S1466252319000197","url":null,"abstract":"<p><p>Systematic reviews and meta-analyses are used to summarize and interpret evidence for clinical decision-making in human health. The extent of the application of these methods in veterinary medicine and animal agriculture is unknown. The goal of this scoping study was to ascertain trends in the publication of systematic reviews and meta-analyses examining animal health, animal performance, and on-farm food safety. Online databases were searched for reviews published between 1993 and 2018 that focused on relevant outcomes in domestic livestock, companion animals, or wildlife species. In total 1787 titles and abstracts underwent data characterization. Dairy cattle, fish, and pigs were the most common target commodity groups. Few articles investigated both health and performance outcomes (only health: n = 418; only performance: n = 701; both health and performance: n = 103). Most of the reviews (67.6%, n = 1208/1787) described a meta-analysis but did not state in the title or abstract that a systematic review was also conducted, which is potentially problematic. Adherence to reporting guidelines is recommended for all systematic reviews and meta-analyses. For research areas with many reviews, an evidence repository is recommended. For less well-reviewed areas, additional investigation may be necessary to identify the reasons for the lack of synthesis research.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"20 2","pages":"116-127"},"PeriodicalIF":2.5,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252319000197","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37662735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
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