Acta Amazonica最新文献_第5页

Antileishmanial and cytotoxic activity of dillapiole n-butyl ether dillapole正丁基醚的抗利什曼原虫和细胞毒活性

4区环境科学与生态学

Acta Amazonica Pub Date : 2023-01-01 DOI: 10.1590/1809-4392202300281

Angela Maria Comapa BARROS, Ana Cristina da Silva PINTO, Fernanda Guilhon SIMPLICIO, Francisco Célio Maia CHAVES, Noam Gadelha da SILVA, Kelson Mota Teixeira de OLIVEIRA, Emersom Silva LIMA, Antonia Maria Ramos FRANCO

{"title":"Antileishmanial and cytotoxic activity of dillapiole n-butyl ether","authors":"Angela Maria Comapa BARROS, Ana Cristina da Silva PINTO, Fernanda Guilhon SIMPLICIO, Francisco Célio Maia CHAVES, Noam Gadelha da SILVA, Kelson Mota Teixeira de OLIVEIRA, Emersom Silva LIMA, Antonia Maria Ramos FRANCO","doi":"10.1590/1809-4392202300281","DOIUrl":"https://doi.org/10.1590/1809-4392202300281","url":null,"abstract":"ABSTRACT Among the neglected diseases, American cutaneous leishmaniasis (ACL) still remains highly endemic in some tropical regions. The currently available drugs for treatment are highly toxic, prompting the search for new therapeutic options. The aim of this study was to evaluate the toxic potential of dillapiole n-butyl ether (DBE) against Leishmania amazonensis and L. guyanensis, as well as its toxicity on human peripheral blood mononuclear cells (PBMCs) in vitro. For cell cytotoxicity, concentrations of DBE that ranged from 7.8 to 500 µM were used for 48 and 72 h. For the evaluation of the antileishmanial activity, DBE was tested at concentrations of 0.28 to 18 µM for 24, 48, and 72 h. A value of 36 µM was used for the amastigote assay. The selectivity index (SI) was determined by dividing the CC50/IC50 (macrophages/promastigotes). DBE exhibited a CC50 of 203.9 ± 0.5 µM in 72 h. DBE inhibited promastigote forms with an IC50 of 3.0 µM for both Leishmania species for 72 h. The standard, Pentacarinat®, showed an IC50 of 2.9 µM and 0.3 µM, respectively. The SI of DBE for both species was 67.9 for 72 h. DBE inhibited intracellular forms of L. amazonensis by 65.5% after 48 h. In molecular modeling, DLpOl-F showed two hydrogen bonds (SER418 and 421). DBE demonstrated promising in vitro antileishmanial potential.","PeriodicalId":51309,"journal":{"name":"Acta Amazonica","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135659242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure of dogs and wild carnivores to canine distemper virus, canine parvovirus, Leishmania infantum, and Toxoplasma gondii in the Xingu River basin, Brazilian Amazon: Prevalence, spatial distribution, and association with land cover types 巴西亚马逊新古河流域犬类和野生食肉动物对犬瘟热病毒、犬细小病毒、婴儿利什曼原虫和刚地弓形虫的暴露:患病率、空间分布及其与土地覆盖类型的关系

4区环境科学与生态学

Acta Amazonica Pub Date : 2023-01-01 DOI: 10.1590/1809-4392202301340

Felipe FORNAZARI, Anaiá da Paixão SEVÁ, Karenina Melo Miranda OLIVEIRA, Pedrita Carvalho Ferreira ASSUNÇÃO, Victor Yunes GUIMARÃES

{"title":"Exposure of dogs and wild carnivores to canine distemper virus, canine parvovirus, Leishmania infantum, and Toxoplasma gondii in the Xingu River basin, Brazilian Amazon: Prevalence, spatial distribution, and association with land cover types","authors":"Felipe FORNAZARI, Anaiá da Paixão SEVÁ, Karenina Melo Miranda OLIVEIRA, Pedrita Carvalho Ferreira ASSUNÇÃO, Victor Yunes GUIMARÃES","doi":"10.1590/1809-4392202301340","DOIUrl":"https://doi.org/10.1590/1809-4392202301340","url":null,"abstract":"ABSTRACT Infectious diseases transmitted by domestic dogs can have important consequences for wildlife health. This study aimed to investigate the exposure to four selected pathogens in dogs and wild carnivores in six municipalities in the Xingu River Basin (Pará state, Brazil). The prevalence of positive animals, their spatial distribution, and the association with land cover types were analyzed. Blood samples from 298 dogs and 11 free-ranging wild carnivores were tested through serological diagnoses. The seroprevalence to canine distemper virus, canine parvovirus, Leishmania infantum, and Toxoplasma gondii was 68.6, 75.4, 14.8, and 47.1%, respectively. The seroprevalence to canine distemper virus and T. gondii was significantly higher in dogs than in wild carnivores. Spatial analyses revealed a broad distribution of seropositive animals, except for animals seropositive to L. infantum, which were concentrated in the southern region close to the margins of the Xingu River. Spatial clusters of seropositive animals were detected for all tested pathogens, indicating areas with a greater risk of exposure. Positive results for canine distemper virus, T. gondii, and L. infantum were associated with different types of land cover, and thus were considered risk factors for pathogen exposure. The high seroprevalence of dogs to canine distemper virus and to canine parvovirus are concerning, suggesting risks of transmission to wild species inhabiting areas close to the surveyed communities.","PeriodicalId":51309,"journal":{"name":"Acta Amazonica","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135613441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A remarkable long-antennate new species of Lamprempis Wheeler & Melander (Diptera, Empididae, Empidinae) from the Brazilian Amazon 一种具有长触角的奇异的新物种;产于巴西亚马逊河流域的小蜂(双翅目，小蜂科，小蜂科)

4区环境科学与生态学

Acta Amazonica Pub Date : 2023-01-01 DOI: 10.1590/1809-4392202301183

Yanca Moreira BIER, José Albertino RAFAEL

引用次数: 0

Predation of a mustached bat, Pteronotus sp. (Mormoopidae), by an Amazon tree boa, Corallus hortulanus (Boidae), in the Brazilian Amazon 在巴西亚马逊，一只髭须蝠被一只亚马逊树蟒Corallus hortulanus捕食

4区环境科学与生态学

Acta Amazonica Pub Date : 2023-01-01 DOI: 10.1590/1809-4392202300150

Eder BARBIER, Narjara Tércia PIMENTEL, Enrico BERNARD

引用次数: 0

Photoprotective and antioxidant effect of babassu mesocarp flour extracts 巴巴苏中果皮粉提取物的光防护和抗氧化作用

4区环境科学与生态学

Acta Amazonica Pub Date : 2023-01-01 DOI: 10.1590/1809-4392202300891

Mércia Machado Araújo LIMA, Yaron Santos ALENCAR, Caroline Martins de JESUS, Tatielle Gomes DIAS, Jaqueline Daniele Santos BARROS, Rosane Nassar Meireles GUERRA, Richard Pereira DUTRA, Aramys Silva REIS

引用次数: 0

Stem growth of multipurpose tree species: net effect of micrometeorological variability assessed by principal component regression 多用途树种的茎生长:主成分回归评估微气象变率的净效应

IF 0.8 4区环境科学与生态学

Acta Amazonica Pub Date : 2022-12-01 DOI: 10.1590/1809-4392202103390

Alan Pena de Souza, R. A. Marenco

{"title":"Stem growth of multipurpose tree species: net effect of micrometeorological variability assessed by principal component regression","authors":"Alan Pena de Souza, R. A. Marenco","doi":"10.1590/1809-4392202103390","DOIUrl":"https://doi.org/10.1590/1809-4392202103390","url":null,"abstract":"ABSTRACT In a typical year in the central Amazon, there is a mild dry season, but its effect on stem growth of multipurpose forest tree species is not yet well known. This study aimed to determine the individual effect of microclimatic parameters on stem growth after removing the influence of intercorrelation among microclimatic variables. Monthly stem diameter increment was measured in six species (46 trees) from January 2018 to December 2020. Microclimatic variables recorded were irradiance, air temperature, rainfall, and vapor pressure deficit. Principal component regression was used to assess the effect of micrometeorological variability on stem growth. On average, stem growth increased with an increase in rainfall and soil water content, but decreased with rise in maximum temperature and maximum vapor pressure deficit. These findings indicate that, when removing the effect of intercorrelation between microclimatic parameters, vapor pressure deficit may, in fact, affect stem growth. We demonstrate that the reduction in stem growth during the dry season can also be related to an increase in maximum temperature and maximum vapor pressure deficit, and not only to a decline in soil water content.","PeriodicalId":51309,"journal":{"name":"Acta Amazonica","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44163181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Phytotechnical performance and resistance to leaf-footed bugs of green maize intercropped with Poaceae in the Amazon savannah 亚马逊稀树草原绿玉米与早熟禾科间作的植物技术性能及对叶足虫的抗性

IF 0.8 4区环境科学与生态学

Acta Amazonica Pub Date : 2022-12-01 DOI: 10.1590/1809-4392202102960

Gabriele Medeiros Hermógenes, Eduardo Medeiros de Oliveira, J. Alves, G. F. Barreto, Yenara Alves Guedes, J. Albuquerque

{"title":"Phytotechnical performance and resistance to leaf-footed bugs of green maize intercropped with Poaceae in the Amazon savannah","authors":"Gabriele Medeiros Hermógenes, Eduardo Medeiros de Oliveira, J. Alves, G. F. Barreto, Yenara Alves Guedes, J. Albuquerque","doi":"10.1590/1809-4392202102960","DOIUrl":"https://doi.org/10.1590/1809-4392202102960","url":null,"abstract":"ABSTRACT Green maize has great economic value, and the consumer market increasingly demands the production of ears for fresh consumption that are free from damage by pest attacks. The aim of this study was to evaluate the performance of varieties of AG1051 green maize and Roraima maize (ethnovariety Milhão) intercropped with dwarf grain sorghum, forage sorghum and millet in an environment of the Amazon savannah. We evaluated phytotechnical characteristics of the maize and damage from the leaf-footed bug (Leptoglossus zonatus). The experiment was set up in a 2 x 4 factorial randomised block design with four replications, where the two maize varieties corresponded to the first factor and four intercropping systems to the second factor. Regarding vegetative and reproductive components, Milhão had a longer cycle, greater plant growth and smaller stem diameter than AG1051, causing plant lodging. The intercropping systems had no influence on the production or quality of maize ears for any of the cultivars under study. Milhão did not differ from the AG1051 hybrid in any ear quality variable (ear length, number of grains per ear, cob diameter, ear weight and total number of ears). The AG1051 cultivar was preferred by L. zonatus, but had the highest yield of commercial ears. The intercropping systems had no influence on the damage caused by the leaf-footed bug.","PeriodicalId":51309,"journal":{"name":"Acta Amazonica","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49542604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

So far from home: first record of Chondromorpha xanthotricha (Diplopoda: Polydesmida: Paradoxosomatidae) in the Brazilian Amazon 离家很远：巴西亚马逊首次记录到黄毛软骨虫（Diplopoda:Polydesmida：Paradosomatidae）

IF 0.8 4区环境科学与生态学

Acta Amazonica Pub Date : 2022-12-01 DOI: 10.1590/1809-4392202103141

T. M. Almeida, L. F. Iniesta, R. S. Bouzan, J. W. Morais

引用次数: 4

Ecological aspects of Rhinoclemmys punctularia punctularia (Testudines: Geoemydidae) in two localities in northern Brazil 巴西北部两个地区马尾松鼻螨的生态学特征

IF 0.8 4区环境科学与生态学

Acta Amazonica Pub Date : 2022-12-01 DOI: 10.1590/1809-4392202201260

E. S. Brito, F. I. Martins, I. Fernandes, D. Pavan, C. Strüssmann

{"title":"Ecological aspects of Rhinoclemmys punctularia punctularia (Testudines: Geoemydidae) in two localities in northern Brazil","authors":"E. S. Brito, F. I. Martins, I. Fernandes, D. Pavan, C. Strüssmann","doi":"10.1590/1809-4392202201260","DOIUrl":"https://doi.org/10.1590/1809-4392202201260","url":null,"abstract":"ABSTRACT Rhinoclemmys punctularia punctularia is the only turtle of the family Geoemydidae with part of its range in Brazil. The species is semi-aquatic and widely distributed across the Amazon basin but is still poorly studied. We evaluated aspects of the population structure, habitat use, seasonal activity, and diet of the species during one year, from the beginning of the rainy season to the end of the dry season, in two headwater localities in the Tocantins and Tapajós river basins, in the state of Pará, Brazil. We captured 45 individuals, 14 in the Tocantins basin and 31 in the Tapajós basin. The size-class frequency distributions of captured individuals did not differ between the two samples. The turtles were most frequently captured in first-order streams, followed by lentic (third-order dammed streams) and second-order streams. The capture rate did not vary significantly between sampling periods (start and peak of the rainy season; start and end of the dry season). The trapping effort to capture a single individual was much higher in the Tapajós basin (1,215 trap-hours) than in the Tocantins basin (136 trap-hours). Overall, the low capture rates confirm the secretive nature of the species in Amazonia and its apparent rarity. The individuals analyzed in this study consumed mainly plants.","PeriodicalId":51309,"journal":{"name":"Acta Amazonica","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67246975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil 巴西帕尔<e:1>州巴西貘(Tapirus terrestris)的血色素沉着病样疾病

IF 0.8 4区环境科学与生态学

Acta Amazonica Pub Date : 2022-12-01 DOI: 10.1590/1809-4392202103581

Adrielli Heloise A. Lima, Américo Meirelles Neto, R. J. Cardoso, N. M. F. Sarmento, Arieli Sousa de Oliveira, M. A. O. Moura, Gerson B. E. Gonzalez, G. Riet-Correa, Manoel Ananis Lopes Soares, P. S. Bezerra Júnior, A. S. Amaral, V. Cerqueira

{"title":"Hemochromatosis-like disease in Brazilian tapirs (Tapirus terrestris) in Pará state, Brazil","authors":"Adrielli Heloise A. Lima, Américo Meirelles Neto, R. J. Cardoso, N. M. F. Sarmento, Arieli Sousa de Oliveira, M. A. O. Moura, Gerson B. E. Gonzalez, G. Riet-Correa, Manoel Ananis Lopes Soares, P. S. Bezerra Júnior, A. S. Amaral, V. Cerqueira","doi":"10.1590/1809-4392202103581","DOIUrl":"https://doi.org/10.1590/1809-4392202103581","url":null,"abstract":"ABSTRACT We report two cases of hemochromatosis-like disease in captive Brazilian tapirs, Tapirus terrestris in Pará state, Brazil. Both animals presented symptoms of chronic hepatopathy associated with marked accumulation of hemosiderin. The coloration of Perls demonstrated pronounced iron accumulation in macrophages in the portal space, Kupffer cells, and, to a lesser extent, in the hepatocytes of the periportal region. Marked portal fibrosis was evidenced by Masson’s trichrome. The pathological mechanisms of this disease in tapirs are not yet well established. It has been suggested that the species may have different mechanisms of iron absorption and elimination, rendering them sensitive to elevation in dietary levels of this metal. Two previous reports of this disease in T. terrestris exist from zoos in Australia and Scotland. This is the first report of this disease in tapirs in Brazil based on histopathological and histochemical findings.","PeriodicalId":51309,"journal":{"name":"Acta Amazonica","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45521736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0