{"title":"Effects of intravenous xylazine versus dexmedetomidine premedication with ketamine-midazolam-isoflurane anaesthesia for castration in horses","authors":"Kavin Ravikumar, Sivashankar Ramakrishnan, Pushkinraj Haridoss, Kannan Thandavan Arthanari","doi":"10.56093/ijans.v94i2.135343","DOIUrl":"https://doi.org/10.56093/ijans.v94i2.135343","url":null,"abstract":"The objectives of this research was to study the sedation and anaesthetic characteristics of intravenous xylazine and dexmedetomidine combined with ketamine-midazolam-isoflurane and to evaluate the cardiopulmonary effects during the anaesthetic period. Stallions were premedicated with xylazine (1.1 mg/kg IV) in Group 1 and dexmedetomidine (3.5 µg/kg IV) in Group 2. Sedation quality was evaluated and scored. General anaesthesia was achieved with ketamine (2.2 mg/kg IV) and midazolam (0.1 mg/kg IV) in both groups and anaesthesia was maintained with isoflurane inhalant in fresh oxygen gas flow (6-8 L/min). All the stallions underwent an orchiectomy by the half- closed method. Cardiovascular variables and pulmonary variables were recorded using multi gas vital sign monitor. Anaesthetic parameters, reflex status and quality of muscle relaxation were assessed. After the surgical procedure, recovery was monitored and scored on 6 point scale. Sedation score and quality was clinically better in Group 2. The difference in cardiopulmonary variables was statistically not significant. However, statistically significant changes were noticed between two groups with regard to some blood gas values during the intra-operative and at 15 min post anaesthetic period. Quality of muscle relaxation was better in group 2. Recovery was not significant. Overall quality of anaesthesia and recovery was almost similar in both the groups. In conclusion, both drug combinations produced satisfactory results for castration in the horses studied. In this study, dexmedetomidine at 3.5 µg/kg and xylazine at 1.1 mg/kg sedative doses did not result in much significant changes compared to one other.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139783384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. R. Jawale, P. K. Bacche, S. Chopde, A. Dhok, S. Kawitkar, R. L. Werulakar, M. Kadam, M. Gole, N. V. Kurkure
{"title":"Phytosome-conjugated carvacrol: A novel approach for improving growth performance, intestinal morphology and economics of production in Broiler Chicken","authors":"M. R. Jawale, P. K. Bacche, S. Chopde, A. Dhok, S. Kawitkar, R. L. Werulakar, M. Kadam, M. Gole, N. V. Kurkure","doi":"10.56093/ijans.v94.i2.141294","DOIUrl":"https://doi.org/10.56093/ijans.v94.i2.141294","url":null,"abstract":"Essential oils are plant-derived aromatic volatile oils, and they contain bioactive compounds that have been shown to improve poultry nutrition. However, considering problems associated with the solubility and bioavailability of polyphenolic compounds, the study was planned to find out the effect of the novel feed-grade delivery system, phytosomes for conjugation of plant-derived polyphenolic compound carvacrol on the growth performance of broiler chickens. The experiment was conducted, on 240 broiler chicks for a period of 6 weeks. The chicks were divided into 4 groups having 4 replicates of 15 birds each. The birds in the control group (T0) offered a standard diet as per BIS (2007) specification. Group T1 received a standard diet supplemented with Bacitracin Methylene Disalicylate (BMD) antibiotic at standard dose and group T2 received a standard diet supplemented with carvacrol essential oil @100 mg/kg feed. Group T3 received a standard diet supplemented with phytosome-conjugated carvacrol essential oil (carvacrol @16.6%) @100 mg/kg feed. The performance of all the treatment groups was assessed with respect to the different performance parameters. The supplementation of phytosome-conjugated carvacrol essential oil (carvacrol @16.6%) @ 100 mg/kg feed was found beneficial in terms of growth performance, feed efficiency, and intestinal morphometry. In terms of economics of broiler production, the results revealed that the addition of phytosome- conjugated carvacrol essential oil and carvacrol essential oil in diets was found beneficial in reducing the cost of broiler production, thereby enhancing the margin of profit in broiler production and fetching higher net profit than the control group.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"63 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. S N, B. Saikia, B. Konwar, H. Bayan, T. R. Devi, Champak Jyoti Das, H. Zorinpuii
{"title":"Comparative studies on haemato-biochemical changes following pre-emptive analgesia with tramadol, pentazocine lactate and meloxicam inpain management of canine ovariohysterectomy","authors":"C. S N, B. Saikia, B. Konwar, H. Bayan, T. R. Devi, Champak Jyoti Das, H. Zorinpuii","doi":"10.56093/ijans.v94i2.132408","DOIUrl":"https://doi.org/10.56093/ijans.v94i2.132408","url":null,"abstract":"The present study was conducted to evaluate the effects of tramadol, pentazocine lactate and meloxicam as pre- emptive analgesics in dogs premedicated with glycopyrrolate, inducted with propofol and maintained with propofol continuous rate infusion (CRI) for certain haematological and biochemical parameters. The animals were randomly divided into three equal groups,viz. Group-T, Group-P and Group-M comprising six animals in each group and all the animals were premedicated with glycopyrrolate. After 10 min of pre-anaesthetic administration, pre-emptive analgesia was given. Blood was collected from cephalic or saphenous vein at intervals 0 (baseline) min before premedication, thereafter at 10 min, 30 min, 1 h, 2 h and 3 h after pre-emptive analgesic administration and haemato- biochemical parameters were recorded. Hb, PCV and TEC were significantly decreased at 30 min and 1 h interval in all the three groups. TLC and glucose concentration were significantly higher in group-M as compared to group-T and group-P at different time intervals. GGT level increased significantly at 30 min in all the three groups. CRP concentration was significantly higher in group-M as compared to group-T. Total protein was significantly decreased at 1 h interval in group-T and group-P, but in group-M such finding was noticed at 2 h interval. Cortisol was significantly lower in group-T in entire study period. The alterations in physiological and haematological parameters caused by tramadol, pentazocine lactate and meloxicam were found to be minimal and within the physiological limits. Tramadol produced less significant rise in CRP and cortisol concentrations which indicated better pain management. Based on the findings of the present study, it is concluded that tramadol is more effective as compared to pentazocine lactate and meloxicam in the management of post-operative pain due to canine ovariohysterectomy.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"208 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139843167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nisha Sharma, R. D, Sushil Kumar, G. R. Gowane, I. Gupta, Archana Verma
{"title":"Factor analysis for udder and teat type traits in Sahiwal and Karan Fries cows","authors":"Nisha Sharma, R. D, Sushil Kumar, G. R. Gowane, I. Gupta, Archana Verma","doi":"10.56093/ijans.v94.i2.115326","DOIUrl":"https://doi.org/10.56093/ijans.v94.i2.115326","url":null,"abstract":"Selecting female cows for productivity based on udder and teat traits is essential in field due to lack of available records. The objective of the present study was to reduce the dimensionality of the 17 udder and teat traits and to analyse their impact on milk productivity. The data on 256 cattle comprising 133 Sahiwal and 123 Karan Fries cows were used in this study over the years 2017-2019 from Livestock Research Centre (LRC) of ICAR-National Dairy Research Institute, Karnal. The 17 udder and teat traits were fore udder attachment (FUA), rear udder width (RUW), rear udder height (RUH), udder balance (UB), udder depth (UD), udder length (UL), udder width (UW), udder circumference (UC), central ligament/udder cleft (CL), teat circumference (TC), fore teat length (FTL), rear teat length (RTL), distance between fore and rear teat (DFR), distance between left and right teat (DLR), shortest distance from floor to fore teat (SDFT), shortest distance from floor to rear teat (SDRT) and teat diameter (TD). In the factor analysis, first five latent factors accounted for 62.22% of total variance in udder and teat measurements for Sahiwal cows and 65.67% in Karan Fries (KF) cows, respectively. In Sahiwal cows F1 represented better udder support and wideness (wide udders, udders were supported by strong suspensory ligament), whereas in KF cows, first factor reflected better udder dimension and distance between teats (longer length, width of udder and well placed teats). Factor analysis could reduce the multicollinearity of the data. It can be concluded that inclusion of udder and teat measurements in selection index can be a reliable criteria for selecting cows for higher milk yield.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"66 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139844314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linda George, V. M R, Oshin, Saleem Yousuf, I. D. Gupta
{"title":"Identification of genetic variants of bGH, GHR and IGF1 gene and their association with lactation persistency in Tharparkar cattle","authors":"Linda George, V. M R, Oshin, Saleem Yousuf, I. D. Gupta","doi":"10.56093/ijans.v94.i2.131533","DOIUrl":"https://doi.org/10.56093/ijans.v94.i2.131533","url":null,"abstract":"Persistency can be explained as number of days during which the high level of milk production is maintained after the peak milk yield. The aim of this study was to identify genetic variants of bovine-Growth Hormone (bGH), Growth Hormone Receptor (GHR) and Insulin like Growth Factor1 (IGF1) gene and their association with lactation persistency in Tharparkar cattle. Study was carried out using data of daily milk yield, monthly test days, total milk yield and peak yield of 372 lactation records of 190 Tharparkar cattle maintained at Livestock Research Centre of ICAR-National Dairy Research Institute from 1996-2019. Lactation persistency was estimated using Woods and Wilminks method and its least squares means were 2.37±0.08 and -5.4±0.56, respectively. Investigations on polymorphism were performed using seven reported primers for amplifying targeted regions of bGH, GHR and IGF1 gene. In PCR-RFLP, bGH-MspI RFLP had shown polymorphism in intron 3 and its genotypic frequencies were TT 0.49, CT 0.39 and CC 0.12. The allelic frequency of C and T were 0.31 and 0.69, respectively. The bGH-AluI RFLP had shown monomorphism in exon 5. GHR-AluI had shown polymorphism in exon 10 with only two genotypes AA and AG with frequency of 0.92 and 0.08, respectively. The frequency of A and G allele was 0.96 and 0.04, respectively. In GHR-StuI and IGF1-TasI in promoter region, RsaI in exon 3 and SnaB I in exon 1 had shown monomorphism. No significant association was found between genetic variants of bGH and GHR with lactation persistency in Tharparkar cattle.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"9 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139783224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Vajpeyee, J. Ramesh, R. Karunakaran, J. Muralidharan, V. Sankar, T. K. Das
{"title":"Effect of different selenium sources on nutrient digestibility, performance and antioxidant status in Mecheri lambs","authors":"S. Vajpeyee, J. Ramesh, R. Karunakaran, J. Muralidharan, V. Sankar, T. K. Das","doi":"10.56093/ijans.v94.i2.135872","DOIUrl":"https://doi.org/10.56093/ijans.v94.i2.135872","url":null,"abstract":"An experiment was conducted to determine the effect of different selenium sources on nutrient digestibility, performance and antioxidant status in Mecheri lambs. Mecheri lambs (30) were distributed randomly into five equal groups (Control, T1, T2, T3 and T4) with six lambs in each, on the basis of average body weight (14.1±1.1 kg). The animals in T1, T2, T3 and T4 were given sodium selenite (0.30 ppm), selenocysteine (0.30 ppm), nano selenium (0.30 ppm) and nano selenium (0.15 ppm), respectively for 120 days. The result revealed that DM, OM, CP, EE, CF, NDF, ADF and NFE digestibility were significantly higher for lambs in group T2 and T3 than other groups. T3 group showed highest nitrogen intake, retention and balance. There was no difference in daily intake, faecal and urinary excretion and balance of Ca and P. There was no effect on DM intake but T3 and T4 group showed significant difference in body weight gain, average daily gain and feed conversion ratio between the experimental groups. All sources of Se showed no effect on biochemical parameters. However, T3 group showed significantly lower MDA content in blood and significantly higher activity of GSH-Px and SOD compared to other groups. In conclusion, dietary supplementation of Nano-Se at 0.30 ppm can be used more efficiently to improve the nutrient digestibility, growth performance and antioxidant status in Mecheri lambs.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"72 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swayamprabha Naik, S. Dash, Jaspreet Singh Arora, P. P. Dubey, S. Sahoo
{"title":"Association of polymorphisms of IGF1 promoter with growth and fertility performance in PB1 parent line of broiler chicken variety","authors":"Swayamprabha Naik, S. Dash, Jaspreet Singh Arora, P. P. Dubey, S. Sahoo","doi":"10.56093/ijans.v94i2.133317","DOIUrl":"https://doi.org/10.56093/ijans.v94i2.133317","url":null,"abstract":"Blood samples from 180 birds pertaining to a single generation of PB1 parent line were collected for present study. The birds were raised under standard management and different growth variables were recorded up to 20 weeks of age. Age at first egg and egg production till 40 weeks of age was recorded in females. PCR-RFLP analysis was used to screen individuals with polymorphisms in IGF1 promoter region and three genotypes AA, AC and CC were identified at frequencies of 0.79, 0.18 and 0.03, respectively. CC homozygotes were lower with respect to their performance in growth and fertility traits. Sequencing results of both alleles revealed T244G transversion mutation in the C allele. Gene regulation analysis confirmed that such transversion resulted in non-binding of Oct-1 transcription factor at 241 to 250 bp in C allele, causing down regulation of the gene. The mutations in the promoter sequence affected the transcriptional gene regulation affecting growth and fertility performance.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"201 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of dietary supplementation of Vitamin E on the resumption of cyclic ovarian activity in Murrah buffaloes","authors":"B. Mili, S. Pandita","doi":"10.56093/ijans.v94.i2.133736","DOIUrl":"https://doi.org/10.56093/ijans.v94.i2.133736","url":null,"abstract":"The postpartum anestrus and silent estrus are the challenging cause for low reproductive efficiency in buffaloes especially in tropical climate conditions. This study was aimed at assessing the effect of dietary supplementation of vitamin E on the resumption of cyclic ovarian activity in periparturient Murrah buffaloes through plasma progesterone (P4) hormone profiles. The Murrah buffaloes (n=12) were selected during their late gestation based on the expected date of calving that fall between November and February, from ICAR-National Dairy Research Institute livestock herd and were divided randomly into two groups (n=6). Buffaloes of group I were given only the control diet, while group II was supplemented with 2000 IU/day/head vitamin E along with control feed. Blood samples were collected from each buffalo at weekly intervals from day +21 to +56 after calving. Plasma P4 was estimated by direct radioimmunoassay (RIA). The results revealed that plasma P4 levels were statistically non-significant between groups except on day 21. However, the overall P4 profile of each buffalo indicated ovarian activity; from day 28 postpartum in supplemented group and day 42 in the control group. From the experiment, it could be inferred that the dietary supplementation of vitamin E has no effect on the resumption of cyclic ovarian activity/ steroidogenesis.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Chavda, H. Savsani, V. K. Karangiya, V. Gamit, N. K. Ribadiya, D. T. Fefar, J. Chavda, P. G. Dodiya
{"title":"Influence of peripartum dietary supplementation of choline and fat in protected form on production performance of Gir cows","authors":"M. Chavda, H. Savsani, V. K. Karangiya, V. Gamit, N. K. Ribadiya, D. T. Fefar, J. Chavda, P. G. Dodiya","doi":"10.56093/ijans.v94.i2.129066","DOIUrl":"https://doi.org/10.56093/ijans.v94.i2.129066","url":null,"abstract":"In this experiment, the effects of supplementing choline and fat in rumen protected form during peripartum period on feed intake, milk production and composition of Gir cows were studied. Twenty four Gir cows of 1st to 3rd parity were used from 30 days pre-partum through 60 days post-partum and randomly assigned to four equal treatment groups (n=6) on the basis of their parity, body weight and previous lactation yield. Control diet was fed to cows in group T1 (control). Additionally, rumen protected choline (RPC) @45 g/d in group T2; rumen protected fat (RPF) 80 g/d in group T3 and RPC @45 g/d + RPF @80 g/d in group T4 were supplemented along with control diet. The treatments significantly affected dry mater intake (DMI) and milk production of cows. DMI was increased in the cows fed with RPC as compared to control. Milk yield, 4% fat-corrected milk, solid-corrected milk and energy- corrected milk were higher in the cows fed with RPC and RPF alone or in combination, as compared to control. No synergistic effect was observed with these supplements on DMI or milk production. None of these supplements influenced the milk composition significantly, however yield of milk fat, protein and lactose were higher in all the nutrient supplemented cows compared to control. Net return over feed cost was higher in supplemented cows compared to control. Results indicated that supplementation of RPC or RPF can improve feed intake and productive performance of Gir cows for overall economic benefits.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"51 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139844949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gopi Marappan, Duraisamy Rajendran, Jenita Monalisa Tellis, H. S. Heena, Nira Manik Soren
{"title":"Rumen microbes: Exploring its potential for productivity and commercial use","authors":"Gopi Marappan, Duraisamy Rajendran, Jenita Monalisa Tellis, H. S. Heena, Nira Manik Soren","doi":"10.56093/ijans.v94i2.137832","DOIUrl":"https://doi.org/10.56093/ijans.v94i2.137832","url":null,"abstract":"Ruminant animals are known for their dairy and meat products worldwide. They are the best converters of poor quality fibrous feed ingredients, and presence of rumen, the anaerobic chamber that harbours vast category of microbes, is attributable to this phenomenon. The microbes include bacteria, fungi, protozoa, archaea and bacteriophages that work on synergistically for optimal performance of ruminant animals. These microbes help not only in digestion of fibrous materials, but also involved in various biological functions, such as probiotic activity, antimicrobial metabolite production, synthesis of health promoting bioactive fatty acid molecules, biomass conversion, etc. Earlier, the probiotic organisms used in food animals (calves, sheep, goat, swine and poultry) were mainly originated from dairy products but today organisms of autochthonous origin are being used, as they show better adaptability. Since, rumen do possess organisms with probiotic and fibre utilising activity, these organisms are now explored for their suitability as a probiotic and fibrolytic agent in monogastric food animals. Diversity of rumen microbes was not properly understood through the conventional culture methods, however with advancement in ‘Omic’ technologies, researchers could identify new class of organisms from the rumen and their potential use for the commercial and industrial purposes.","PeriodicalId":512390,"journal":{"name":"The Indian Journal of Animal Sciences","volume":"11 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}