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Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews最新文献

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Integrating computational methods to predict mutagenicity of aromatic azo compounds. 结合计算方法预测芳香偶氮化合物的致突变性。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-10-02 Epub Date: 2017-11-27 DOI: 10.1080/10590501.2017.1391521
Domenico Gadaleta, Nicola Porta, Eleni Vrontaki, Serena Manganelli, Alberto Manganaro, Guido Sello, Masamitsu Honma, Emilio Benfenati
{"title":"Integrating computational methods to predict mutagenicity of aromatic azo compounds.","authors":"Domenico Gadaleta,&nbsp;Nicola Porta,&nbsp;Eleni Vrontaki,&nbsp;Serena Manganelli,&nbsp;Alberto Manganaro,&nbsp;Guido Sello,&nbsp;Masamitsu Honma,&nbsp;Emilio Benfenati","doi":"10.1080/10590501.2017.1391521","DOIUrl":"https://doi.org/10.1080/10590501.2017.1391521","url":null,"abstract":"<p><p>Azo dyes have several industrial uses. However, these azo dyes and their degradation products showed mutagenicity, inducing damage in environmental and human systems. Computational methods are proposed as cheap and rapid alternatives to predict the toxicity of azo dyes. A benchmark dataset of Ames data for 354 azo dyes was employed to develop three classification strategies using knowledge-based methods and docking simulations. Results were compared and integrated with three models from the literature, developing a series of consensus strategies. The good results confirm the usefulness of in silico methods as a support for experimental methods to predict the mutagenicity of azo compounds.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 4","pages":"239-257"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1391521","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35505368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Recent trends in common chemical feed and food contaminants in Israel. 以色列常见化学饲料和食品污染物的最新趋势。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-10-02 Epub Date: 2017-11-27 DOI: 10.1080/10590501.2017.1391507
J A Shimshoni, S Barel
{"title":"Recent trends in common chemical feed and food contaminants in Israel.","authors":"J A Shimshoni,&nbsp;S Barel","doi":"10.1080/10590501.2017.1391507","DOIUrl":"https://doi.org/10.1080/10590501.2017.1391507","url":null,"abstract":"<p><p>In February 2014 a new law was approved by the Israeli parliament, namely the Control of Animal Feed Law. The law intends to regulate the production and marketing of animal feed. In preparation for the law's implementation in 2017, we have assessed the current feed and food safety challenges in Israel in recent years in association with the presence of common undesirable contaminants in various common feed and food commodities. Tight collaboration between regulatory authorities and feed/food industry, enhanced feed and food quality monitoring, transparency of survey results and readily accessible and reliable information for the public about health hazards of chemical contaminants, will guarantee the safety and quality of food and feed.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 4","pages":"189-212"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1391507","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35615541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Effects of chronic alcohol consumption on DNA damage and immune regulation induced by the environmental pollutant dibenzo[a,l]pyrene in oral tissues of mice. 慢性饮酒对环境污染物二苯并[a,l]芘致小鼠口腔组织DNA损伤及免疫调节的影响
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-10-02 Epub Date: 2017-12-04 DOI: 10.1080/10590501.2017.1391514
Kun-Ming Chen, Todd D Schell, John P Richie, Yuan-Wan Sun, Shang-Min Zhang, Ana Calcagnotto, Cesar Aliaga, Krishne Gowda, Shantu Amin, Karam El-Bayoumy
{"title":"Effects of chronic alcohol consumption on DNA damage and immune regulation induced by the environmental pollutant dibenzo[a,l]pyrene in oral tissues of mice.","authors":"Kun-Ming Chen,&nbsp;Todd D Schell,&nbsp;John P Richie,&nbsp;Yuan-Wan Sun,&nbsp;Shang-Min Zhang,&nbsp;Ana Calcagnotto,&nbsp;Cesar Aliaga,&nbsp;Krishne Gowda,&nbsp;Shantu Amin,&nbsp;Karam El-Bayoumy","doi":"10.1080/10590501.2017.1391514","DOIUrl":"https://doi.org/10.1080/10590501.2017.1391514","url":null,"abstract":"<p><p>Previously, we showed that oral application of the environmental pollutant dibenzo[a,l]pyrene (DB[a,l]P) induces oral tumors in mice. Thus, in the present investigation we examined the effect of alcohol on DB[a,l]P-induced DNA damage and immune regulation; we showed that alcohol (6.4% v/v in the diet, 35% of Calories) significantly enhanced the levels of (-)-anti-trans-DB[a,l]P-dA while decreased the levels of GSH in the mouse oral tissues. Analysis of RNA expression revealed that DB[a,l]P alone upregulates inflammatory genes while alcohol suppresses several markers of immune surveillance. Collectively, these results suggest that alcohol may enhance oral carcinogenesis induced by DB[a,l]P.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 4","pages":"213-222"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1391514","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35525500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Exploring the activities of ruthenium nanomaterials as reactive oxygen species scavengers. 探讨钌纳米材料作为活性氧清除剂的活性。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-10-02 Epub Date: 2017-12-08 DOI: 10.1080/10590501.2017.1391516
Gao-Juan Cao, Xiumei Jiang, Hui Zhang, Jiwen Zheng, Timothy R Croley, Jun-Jie Yin
{"title":"Exploring the activities of ruthenium nanomaterials as reactive oxygen species scavengers.","authors":"Gao-Juan Cao,&nbsp;Xiumei Jiang,&nbsp;Hui Zhang,&nbsp;Jiwen Zheng,&nbsp;Timothy R Croley,&nbsp;Jun-Jie Yin","doi":"10.1080/10590501.2017.1391516","DOIUrl":"https://doi.org/10.1080/10590501.2017.1391516","url":null,"abstract":"<p><p>Research on noble metal nanoparticles (NPs) able to scavenge reactive oxygen species (ROS) has undergone a tremendous growth recently. However, the interactions between ruthenium nanoparticles (Ru NPs) and ROS have never been systematically explored thus far. This research focused on the decomposition of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), scavenging of hydroxyl radicals (<sup>•</sup>OH), superoxide radical (O<sub>2</sub><sup>•-</sup>), singlet oxygen (<sup>1</sup>O<sub>2</sub>), 2,2'-azino-bis(3-ethylbenzenothiazoline- 6-sulfonic acid ion (ABTS<sup>•+</sup>), and 1,1-diphenyl-2-picrylhydrazyl radical (<sup>•</sup>DPPH) in the presence of commercial Ru NPs using the electron spin resonance technique. In vitro cell studies demonstrated that Ru NPs have excellent biocompatibility and exert a cytoprotective effect against oxidative stress. These findings may spark fresh enthusiasm for the applications of Ru NPs under relevant physiologically conditions.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 4","pages":"223-238"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1391516","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35583269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids. 免疫分析法诊断吡咯利西啶类生物碱暴露。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-07-03 Epub Date: 2017-05-16 DOI: 10.1080/10590501.2017.1328828
Na Li, Fan Zhang, Wei Lian, Huali Wang, Jiang Zheng, Ge Lin
{"title":"Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids.","authors":"Na Li,&nbsp;Fan Zhang,&nbsp;Wei Lian,&nbsp;Huali Wang,&nbsp;Jiang Zheng,&nbsp;Ge Lin","doi":"10.1080/10590501.2017.1328828","DOIUrl":"https://doi.org/10.1080/10590501.2017.1328828","url":null,"abstract":"<p><p>Numerous pyrrolizidine alkaloid (PA) poisoning cases have been documented worldwide. Protein covalent binding with reactive metabolites generated from metabolic activation of PAs to form pyrrole-protein adducts is suggested to be a primary mechanism of PA-induced toxicities. The present study aimed to develop antibodies for diagnosis of PA exposure. Polyclonal antibodies were raised in rabbits and proven to specifically recognize pyrrole-protein adducts regardless of amino acid residues modified by the reactive metabolites of PAs. The developed antibodies were successfully applied to detect pyrrole-protein adducts in blood samples obtained from PA-treated rats and exhibited a potential for the clinical diagnosis of PA exposure.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 3","pages":"127-139"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1328828","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34996518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Evaluation of chemical mutagenicity using next generation sequencing: A review. 利用新一代测序技术评价化学致突变性:综述。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-07-03 Epub Date: 2017-05-16 DOI: 10.1080/10590501.2017.1328831
Hua Du, Bohu Pan, Tao Chen
{"title":"Evaluation of chemical mutagenicity using next generation sequencing: A review.","authors":"Hua Du,&nbsp;Bohu Pan,&nbsp;Tao Chen","doi":"10.1080/10590501.2017.1328831","DOIUrl":"https://doi.org/10.1080/10590501.2017.1328831","url":null,"abstract":"<p><p>Mutations are heritable changes in the nucleotide sequence of DNA that can lead to many adverse effects. Genotoxicity assays have been used to identify chemical mutagenicity. Recently, next generation sequencing (NGS) has been used for this purpose. In this review, we present the progress in NGS application for assessing mutagenicity of chemicals, including the methods used for detecting the induced mutations, bioinformatics tools for analyzing the sequencing data, and chemicals whose mutagenicity has been evaluated using NGS. Available information suggests that NGS technology has unparalleled advantages for evaluating mutagenicity of chemicals can be applied for the next generation of mutagenicity tests.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 3","pages":"140-158"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1328831","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34996521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Formation of iron oxide/Pd hybrid nanostructures with enhanced peroxidase-like activity and catalytic reduction of 4-nitrophenol. 形成具有增强过氧化物酶样活性和催化还原4-硝基苯酚的氧化铁/钯杂化纳米结构。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-07-03 Epub Date: 2017-05-22 DOI: 10.1080/10590501.2017.1328839
Jing Li, Junhui Cai, Huimin Jia, Lixia Zhang, Yan Lei, Weiwei He, Jun-Jie Yin
{"title":"Formation of iron oxide/Pd hybrid nanostructures with enhanced peroxidase-like activity and catalytic reduction of 4-nitrophenol.","authors":"Jing Li,&nbsp;Junhui Cai,&nbsp;Huimin Jia,&nbsp;Lixia Zhang,&nbsp;Yan Lei,&nbsp;Weiwei He,&nbsp;Jun-Jie Yin","doi":"10.1080/10590501.2017.1328839","DOIUrl":"https://doi.org/10.1080/10590501.2017.1328839","url":null,"abstract":"<p><p>Iron oxide/Pd hybrid nanostructures with controllable Pd loading from 0.05 to 1.0 (calculated as Pd/Fe molar ratio) have been synthesized by chemical reduction of Pd<sup>2+</sup> on iron oxide particles. The combination of iron oxide and Pd exhibits enhanced peroxidase-like activity and catalytic activity toward reduction of 4-nitrophenol. The catalytic enhancements were found to be dependent on the Pd loading amount as well as the synergistic effect between iron oxide and Pd. These results suggest that iron oxide with unique surface chemical state can be an active supporter and suggest an effective way to design superior hybrid nanostructures for catalytic applications.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 3","pages":"159-172"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1328839","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35017090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
A decision tree approach to screen drinking water contaminants for multiroute exposure potential in developing guideline values. 用决策树方法筛选饮用水污染物的多途径暴露潜力，以制定指标值。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-07-03 DOI: 10.1080/10590501.2017.1328844
Kannan Krishnan, Richard Carrier
{"title":"A decision tree approach to screen drinking water contaminants for multiroute exposure potential in developing guideline values.","authors":"Kannan Krishnan,&nbsp;Richard Carrier","doi":"10.1080/10590501.2017.1328844","DOIUrl":"https://doi.org/10.1080/10590501.2017.1328844","url":null,"abstract":"ABSTRACT The consideration of inhalation and dermal routes of exposures in developing guideline values for drinking water contaminants is important. However, there is no guidance for determining the eligibility of a drinking water contaminant for its multiroute exposure potential. The objective of the present study was to develop a 4-step framework to screen chemicals for their dermal and inhalation exposure potential in the process of developing guideline values. The proposed framework emphasizes the importance of considering basic physicochemical properties prior to detailed assessment of dermal and inhalation routes of exposure to drinking water contaminants in setting guideline values.","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 3","pages":"173-187"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1328844","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35061375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids. 7-谷胱甘肽吡咯和7-半胱氨酸吡咯是吡咯利西啶类生物碱的潜在致癌代谢物。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-04-03 Epub Date: 2017-03-01 DOI: 10.1080/10590501.2017.1298358
Xiaobo He, Qingsu Xia, Peter P Fu
{"title":"7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids.","authors":"Xiaobo He,&nbsp;Qingsu Xia,&nbsp;Peter P Fu","doi":"10.1080/10590501.2017.1298358","DOIUrl":"https://doi.org/10.1080/10590501.2017.1298358","url":null,"abstract":"<p><p>Many pyrrolizidine alkaloids (PAs) are hepatotoxic, genotoxic, and carcinogenic phytochemicals. Metabolism of PAs in vivo generates four (±)-6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-DNA adducts that have been proposed to be responsible for PA-induced liver tumor formation in rats. In this present study, we determined that the same set of DHP-DNA adducts was formed upon the incubation of 7-glutathione-DHP and 7-cysteine-DHP with cultured human hepatocarcinoma HepG2 cells. These results suggest that 7-glutathione-DHP and 7-cysteine-DHP are reactive metabolites of PAs that can bind to cellular DNA to form DHP-DNA adducts in HepG2 cells, and can potentially initiate liver tumor formation.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 2","pages":"69-83"},"PeriodicalIF":0.0,"publicationDate":"2017-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1298358","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34921638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Key challenges for nanotechnology: Standardization of ecotoxicity testing. 纳米技术的主要挑战:生态毒性测试的标准化。
Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-04-03 Epub Date: 2017-02-22 DOI: 10.1080/10590501.2017.1298361
Cristina Cerrillo, Gotzone Barandika, Amaya Igartua, Olatz Areitioaurtena, Gemma Mendoza
{"title":"Key challenges for nanotechnology: Standardization of ecotoxicity testing.","authors":"Cristina Cerrillo,&nbsp;Gotzone Barandika,&nbsp;Amaya Igartua,&nbsp;Olatz Areitioaurtena,&nbsp;Gemma Mendoza","doi":"10.1080/10590501.2017.1298361","DOIUrl":"https://doi.org/10.1080/10590501.2017.1298361","url":null,"abstract":"<p><p>Nanotechnology is expected to contribute to the protection of the environment, but many uncertainties exist regarding the environmental and human implications of manufactured nanomaterials (MNMs). Contradictory results have been reported for their ecotoxicity to aquatic organisms, which constitute one of the most important pathways for their entrance and transfer throughout the food web. The present review is focused on the international strategies that are laying the foundations of the ecotoxicological assessment of MNMs. Specific advice is provided on the preparation of MNM dispersions in the culture media of the organisms, which is considered a key factor to overcome the limitations in the standardization of the test methodologies.</p>","PeriodicalId":51085,"journal":{"name":"Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews","volume":"35 2","pages":"104-126"},"PeriodicalIF":0.0,"publicationDate":"2017-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10590501.2017.1298361","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34976009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
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