用决策树方法筛选饮用水污染物的多途径暴露潜力，以制定指标值。

Q2 Biochemistry, Genetics and Molecular Biology

Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2017-07-03 DOI:10.1080/10590501.2017.1328844

Kannan Krishnan, Richard Carrier

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引用次数: 0

摘要

在制定饮用水污染物指导值时，考虑吸入途径和皮肤接触途径是很重要的。然而，没有指导方针来确定饮用水污染物的多途径暴露潜力的合格性。本研究的目的是建立一个四步框架，在制定指导值的过程中筛选化学物质的皮肤和吸入暴露潜力。拟议的框架强调了在制定指导值时，在详细评估接触饮用水污染物的皮肤和吸入途径之前考虑基本物理化学性质的重要性。

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A decision tree approach to screen drinking water contaminants for multiroute exposure potential in developing guideline values.

ABSTRACT The consideration of inhalation and dermal routes of exposures in developing guideline values for drinking water contaminants is important. However, there is no guidance for determining the eligibility of a drinking water contaminant for its multiroute exposure potential. The objective of the present study was to develop a 4-step framework to screen chemicals for their dermal and inhalation exposure potential in the process of developing guideline values. The proposed framework emphasizes the importance of considering basic physicochemical properties prior to detailed assessment of dermal and inhalation routes of exposure to drinking water contaminants in setting guideline values.

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来源期刊

Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews 环境科学-毒理学

CiteScore

6.20

自引率

0.00%

发文量

审稿时长

>24 weeks

期刊介绍： Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews aims at rapid publication of reviews on important subjects in various areas of environmental toxicology, health and carcinogenesis. Among the subjects covered are risk assessments of chemicals including nanomaterials and physical agents of environmental significance, harmful organisms found in the environment and toxic agents they produce, and food and drugs as environmental factors. It includes basic research, methodology, host susceptibility, mechanistic studies, theoretical modeling, environmental and geotechnical engineering, and environmental protection. Submission to this journal is primarily on an invitational basis. All submissions should be made through the Editorial Manager site, and are subject to peer review by independent, anonymous expert referees. Please review the instructions for authors for manuscript submission guidance.