Oral Science International最新文献_第2页

A case of a giant Bailey type I lateral cervical cyst 巨型贝利 I 型颈椎外侧囊肿病例

Oral Science International Pub Date : 2024-05-09 DOI: 10.1002/osi2.1249

S. Seki, Akira Nishiura, Fumika Kishino, Yusuke Yokota, E. Isomura, Susumu Tanaka

引用次数: 0

Inhibitory effects of alkyl‐galactosides on the coaggregation of Fusobacterium nucleatum and oral bacteria 烷基半乳糖苷对核酸镰刀菌和口腔细菌聚集的抑制作用

Oral Science International Pub Date : 2024-05-05 DOI: 10.1002/osi2.1245

Teppei Tajikara, Morihide Itano, Yoshitaka Yano, Natsuko Toshida, K. Ueno, Yoichiro Miyake

{"title":"Inhibitory effects of alkyl‐galactosides on the coaggregation of Fusobacterium nucleatum and oral bacteria","authors":"Teppei Tajikara, Morihide Itano, Yoshitaka Yano, Natsuko Toshida, K. Ueno, Yoichiro Miyake","doi":"10.1002/osi2.1245","DOIUrl":"https://doi.org/10.1002/osi2.1245","url":null,"abstract":"Coaggregation and coadhesion are important mechanisms for oral bacteria to colonize the oral cavity and exert pathogenic effects. Fusobacterium nucleatum has been reported to coaggregate with various oral bacteria. Some of the coaggregation are inhibited by D‐galactose. D‐galactose, however, will be metabolized by oral bacteria when applied to the oral cavity, resulting in the acid generation that causes dental caries. In the present study, we developed a novel material, alkyl‐galactosides, that inhibits the coaggregation of F. nucleatum and is not metabolized by oral bacteria.Acid production from alkyl‐galactoside by Streptococcus mutans was determined by pH lowering during liquid culture. Antibacterial activity was measured using the minimum inhibitory concentration test, and coaggregation inhibitory effects were evaluated based on the relative coaggregation ratio between F. nucleatum and several oral bacteria using absorbance measurements.D‐galactose was rapidly metabolized by S. mutans, resulting in a decreased pH. Alkyl‐galactoside, however, was not metabolized by the bacterium at 1 mM. Minimum inhibitory concentration of alkyl‐galactoside against S. mutans is 1–4 mM. Alkyl‐galactoside inhibited coaggregation between F. nucleatum and several oral bacteria almost to the same extent as D‐galactose.Alkyl‐galactoside inhibits coaggregation between F. nucleatum and oral bacteria and is not assimilated by oral bacteria suggesting to be a potent novel material for prevention of dental plaque formation.","PeriodicalId":510615,"journal":{"name":"Oral Science International","volume":"317 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of crista galli morphology and morphometry in individuals with cleft lip and palate: A three‐dimensional analysis 评估唇腭裂患者的嵴韧带形态和形态测量：三维分析

Oral Science International Pub Date : 2024-03-24 DOI: 10.1002/osi2.1238

T. Ozturk, Sertan Soylu, Aykagan Cukurluoglu

{"title":"Assessment of crista galli morphology and morphometry in individuals with cleft lip and palate: A three‐dimensional analysis","authors":"T. Ozturk, Sertan Soylu, Aykagan Cukurluoglu","doi":"10.1002/osi2.1238","DOIUrl":"https://doi.org/10.1002/osi2.1238","url":null,"abstract":"The crista galli (CG), located in the anterior cranial fossa and associated with the cranial structures here, is a bony prominence on the ethmoid bone. In this study, we aimed to examine the anatomical variations and pneumatization status of the CG in individuals with cleft lip and palate (CLP) and to compare them with those of individuals without CLP.Data from 16‐ to 25‐year‐old individuals with non‐syndromic cleft lip and palate and control individuals without any syndrome or disease who underwent cone beam computed tomography were used. Measurement of the CG height (superoinferior, on the coronal section), width (laterolateral, on the axial section), and length (anteroposterior, on the axial section) dimensions. In addition, a categorical evaluation of CG morphology, CG pneumatization, olfactory fossa depth, and position of the CG in the ethmoid area (Keros classification) was performed.Although the superoinferior diameter and laterolateral diameter values of the CG did not differ between the groups, the anteroposterior diameter values were found to be significantly (p = 0.047) lower in individuals with CLP (11.95 ± 2.57 mm) compared with control (13.23 ± 2.05 mm). There was no difference in the morphology or pneumatization status of the CG between the groups.Except for the anteroposterior length, there was no difference in CG morphometric measurements between individuals with CLP and control. The anteroposterior length was shorter in individuals with CLP.","PeriodicalId":510615,"journal":{"name":"Oral Science International","volume":" 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140385315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthognathic surgery in a patient with osteogenesis imperfecta and low von Willebrand factor 一名成骨不全症和低冯-威廉因子患者的正颌外科手术

Oral Science International Pub Date : 2024-02-29 DOI: 10.1002/osi2.1235

Akio Himejima, Shuji Ueno, Koji Yamada, Masayuki Kamitani, Chikako Hosoyama, T. Iseki

引用次数: 0

Involvement of ferroptosis‐defensive xCT/GPX4 axis in radioresistance and its impacts on prognosis in oral squamous cell carcinoma 口腔鳞状细胞癌放射耐药性中铁蛋白-防御性 xCT/GPX4 轴的参与及其对预后的影响

Oral Science International Pub Date : 2024-02-27 DOI: 10.1002/osi2.1227

Kohei Ishikawa, Y. Matsuoka, Kosuke Shinohara, Junki Inoue, H. Yano, Takafumi Eto, Tatsuro Yamamoto, K. Yamana, Shunsuke Gohara, H. Takeshita, Masatoshi Hirayama, K. Kawahara, A. Hirosue, Y. Fukugawa, R. Yoshida, Yoshihiro Komohara, Hideki Nakayama

{"title":"Involvement of ferroptosis‐defensive xCT/GPX4 axis in radioresistance and its impacts on prognosis in oral squamous cell carcinoma","authors":"Kohei Ishikawa, Y. Matsuoka, Kosuke Shinohara, Junki Inoue, H. Yano, Takafumi Eto, Tatsuro Yamamoto, K. Yamana, Shunsuke Gohara, H. Takeshita, Masatoshi Hirayama, K. Kawahara, A. Hirosue, Y. Fukugawa, R. Yoshida, Yoshihiro Komohara, Hideki Nakayama","doi":"10.1002/osi2.1227","DOIUrl":"https://doi.org/10.1002/osi2.1227","url":null,"abstract":"Radiotherapy, the mainstay treatment for patients with advanced oral squamous cell carcinoma (OSCC), has low clinical efficacy, resulting in poor prognosis. Radiation induces ferroptosis, a form of cell death driven by iron‐dependent lipid peroxidation. Since the xCT/glutathione peroxidase 4 (GPX4) axis is predominantly involved in the ferroptosis defense system, targeting this axis may potentiate cancer cell vulnerability to ferroptosis.We examined the expression of xCT and GPX4 in the tumor cells of biopsy specimens using immunohistochemistry and evaluated the radiation‐mediated antitumor effects of the ferroptosis inducers, erastin and RSL3, that act by inhibiting xCT and GPX4, respectively.Univariate analysis revealed that high immunohistochemical expression of xCT was correlated with shorter survival, and high GPX4 expression was an independent poor prognostic factor, indicating that the xCT/GPX4 axis influences the clinical outcome of OSCC. Analyses using two types of OSCC cell lines revealed that the clonogenic survival of irradiated cells was increased by the ferroptosis inhibitor ferrostatin‐1 and decreased by erastin and RSL3. The enhanced antitumor effects of erastin and RSL3 were accompanied by increased lipid peroxidation, which was suppressed by the iron chelator deferoxamine. Erastin and RSL3 enhance the effects of radiation on OSCC cells in a mouse xenograft model; these effects were associated with increased expression of the lipid peroxidation marker 4‐hydroxynonenal in tumor cells.xCT/GPX4 axis is involved in the tumor resistance against radiation through the inhibition of ferroptosis in OSCC. Furthermore, radiotherapy combined with ferroptosis induction by targeting the xCT/GPX4 axis may improve patient prognosis in advanced OSCC.","PeriodicalId":510615,"journal":{"name":"Oral Science International","volume":"30 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140425023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of panoramic radiographs findings of cementum‐osseous dysplasia with calcification in the department of oral surgery at hospital: A retrospective study 医院口腔外科全景X光片发现牙骨质发育不良伴钙化的患病率：回顾性研究

Oral Science International Pub Date : 2024-02-21 DOI: 10.1002/osi2.1234

Kazumichi Sato, Kinue Kurihara, Aya Tanaka, Masayasu Yoshida, Kazumi Sekiya, Ken Ishizaki

{"title":"Prevalence of panoramic radiographs findings of cementum‐osseous dysplasia with calcification in the department of oral surgery at hospital: A retrospective study","authors":"Kazumichi Sato, Kinue Kurihara, Aya Tanaka, Masayasu Yoshida, Kazumi Sekiya, Ken Ishizaki","doi":"10.1002/osi2.1234","DOIUrl":"https://doi.org/10.1002/osi2.1234","url":null,"abstract":"Cemento‐osseous dysplasia (COD) is a benign, non‐neoplastic, fibro‐osseous lesion that is often asymptomatic and discovered incidentally on dental radiographs. Radiological examination, rather than biopsy, is recommended for diagnosis because of the risk of infection. The dentist working at a hospital sometimes requests a family dentist to follow up on the progress of COD discovered accidentally during panoramic radiography at a hospital. However, there are few reports on the prevalence of COD on panoramic radiographs obtained at the oral surgery department of a hospital; therefore, we investigated this in this study.We examined the prevalence of COD with calcification (classification, presence of infection, and complications with simple bone cysts) in 1194 patients for whom panoramic radiographs were obtained.Twelve patients (1.0%) had findings of COD with calcification: four cases of periapical COD (three females and one male), five cases of focal COD (four females and one male), and three cases of florid COD (three females and zero males). Infection was seen in one case of Florid COD and one case of Focal COD. A simple bone cyst was observed in one patient with Florid COD.COD with calcification was observed in a certain percentage of patients, and many were asymptomatic. Dental healthcare workers need to understand that COD carries a risk of infection and that there are diseases that need to be differentiated. Patients should also be advised about the need for long‐term follow‐up.","PeriodicalId":510615,"journal":{"name":"Oral Science International","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140444114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treating lower lip fistulas in Van der Woude syndrome using inverted‐T lip reduction: An experience 利用倒 T 形缩唇术治疗范德乌德综合征的下唇瘘：经验之谈

Oral Science International Pub Date : 2024-02-21 DOI: 10.1002/osi2.1232

Rika Narita, Hideto Saijo, M. Kashiwagi, Sachi Oshima, Asako Taniguchi, Kazuto Hoshi

{"title":"Treating lower lip fistulas in Van der Woude syndrome using inverted‐T lip reduction: An experience","authors":"Rika Narita, Hideto Saijo, M. Kashiwagi, Sachi Oshima, Asako Taniguchi, Kazuto Hoshi","doi":"10.1002/osi2.1232","DOIUrl":"https://doi.org/10.1002/osi2.1232","url":null,"abstract":"Van der Woude syndrome is characterized by the concurrence of cleft lip and palate with lower lip fistulas. During fistula resection, care must be taken to maintain the function of the orbicularis oris and restore the normal shape of the lips. Several reports have documented various resection methods; however, the most appropriate surgical resection is controversial. In this report, lower lip fistulas were resected using an inverted‐T surgical design.Of the six patients with Van der Woude syndrome who underwent resection of the lower lip fistula in our department between January 2007 and December 2015, three patients who underwent inverted‐T lip reduction were included. The postoperative position‐dependent morphology of the fistulas was examined.Five years postoperatively, no complications such as postoperative infections, mucous retention cyst formation, a dysmorphic appearance of the lip, or fistula recurrence were observed. Moreover, a stable wound morphology was evident.The inverted‐T lip reduction seems to be promising technique for the excision of lower lip fistulas in patients with Van der Woude syndrome, yielding good results.","PeriodicalId":510615,"journal":{"name":"Oral Science International","volume":"196 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140443607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance of a deep learning system for simultaneously diagnosing radiolucent and radiopaque lesions in the anterior maxilla on panoramic radiographs 深度学习系统同时诊断全景X光片上上颌骨前部不透光和不透光病变的性能

Oral Science International Pub Date : 2024-02-19 DOI: 10.1002/osi2.1233

Kaori Ebata, Yoshitaka Kise, Takahiko Morotomi, E. Ariji

{"title":"Performance of a deep learning system for simultaneously diagnosing radiolucent and radiopaque lesions in the anterior maxilla on panoramic radiographs","authors":"Kaori Ebata, Yoshitaka Kise, Takahiko Morotomi, E. Ariji","doi":"10.1002/osi2.1233","DOIUrl":"https://doi.org/10.1002/osi2.1233","url":null,"abstract":"To validate the performance of a deep learning system with detection and classification functions for a mix of radiolucent and radiopaque lesions in the anterior maxilla on panoramic radiographs.Patients with radiolucent or radiopaque lesions in the anterior maxilla on panoramic radiographs were selected retroactively from May 2022 until Feb 2002 to obtain 100 preoperative radiographs each for nasopalatine duct cysts (NDCs), radicular cysts (RCs), and impacted supernumerary teeth (ISTs). An additional 100 patients with no lesions in the anterior maxilla were selected. Two deep learning systems (Systems 1 and 2) were created and tested. For System 1, the models were created and tested using datasets of radiolucent lesions (NDCs and RCs) and No lesions. For developing System 2, the data of radiopaque lesions (ISTs) were added to those used in System 1. The neural network used was You Only Look Once ver. 7 (YOLOv7). The recall, precision, F1 score, and accuracy calculated from the confusion matrix were used to evaluate diagnostic performance.The performance of System 2, which included the IST data, was worse than that of System 1. Even when NDCs and RCs were addressed as a joint category of radiolucent lesions, the addition of IST data resulted in a worse performance than that of System 1.Our results indicate that combined use of radiopaque lesions (ISTs) with radiolucent lesions (NDCs and RCs) reduces the deep learning performance for radiolucent lesions with the volume of data used in the present study.","PeriodicalId":510615,"journal":{"name":"Oral Science International","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple myeloma in the mandible mimicking a radicular cyst: A case report and literature review 下颌骨多发性骨髓瘤模仿放射性囊肿：病例报告和文献综述

Oral Science International Pub Date : 2024-01-31 DOI: 10.1002/osi2.1229

Y. Shimada, Hideki Miyazaki, Akira Hangaishi, Yutaka Maruoka

引用次数: 0

Elevated alveolar bone mineral density in female patients undergoing bisphosphonate therapy: A pilot cross‐sectional study using intraoral radiographs 接受双膦酸盐治疗的女性患者牙槽骨矿物质密度升高：使用口腔内X光片进行的横断面试验研究

Oral Science International Pub Date : 2024-01-30 DOI: 10.1002/osi2.1231

Ryutaro Ono, Mariko Kano, Yumi Fujikawa, Toshiro Yamamoto, N. Kanamura

引用次数: 0