Orthognathic surgery in a patient with osteogenesis imperfecta and low von Willebrand factor

Abstract

This report describes the case of a patient with jaw deformity, osteogenesis imperfecta (OI), and low von Willebrand factor (low VWF).A 30‐year‐old woman with OI was referred for the treatment of prognathism of the lower jaw. Laboratory data showed that partial thromboplastin time was slightly increased, so additional testing was performed and revealed low VWF. The patient was then administered 1‐desamino‐8‐D‐arginine vasopressin before orthognathic surgery and experienced no hemorrhagic episodes perioperatively.As both OI patients and low VWF patients are at greater risk of hemorrhage, surgery in such cases should be performed with due consideration of and preparation for bleeding.