Turkish Journal of Clinics and Laboratory最新文献

{"title":"Çocuklarda COVID-19 sonrası streptokokal tonsillofarenjit sıklığındaki değişiklikler","authors":"Yunus Nas, Süveyda Gözüküçük","doi":"10.18663/tjcl.1440105","DOIUrl":"https://doi.org/10.18663/tjcl.1440105","url":null,"abstract":"Amaç: Koronavirus hastalığı 2019 (COVID-19) pandemisi öncesi ve sonrasında Streptococcus pyogenes (GAS) tonsillofarenjit sıklığında yaşanan değişikliklere ilişkin kapsamlı veriler yetersizdir. Bu çalışmada, COVID-19 dönemi öncesi, sırası ve sonrasında çocuklarda GAS sıklığında meydana gelen değişiklikleri incelemeyi amaçlanmıştır. \u0000Gereç ve Yöntemler: Bu retrospektif çalışmaya, Haziran 2018 ile Haziran 2023 tarihleri arasında klinik bulgularla bakteriyel tonsillofarenjit ön tanısı alan 13,061 çocuk hasta dahil edildi. Tüm hastalara Strep A antijen testi yapılmış ve boğaz sürüntü örnekleri toplanmıştır. Hastalar, hastaneye başvuru tarihlerine göre üç gruba ayrıldı: Grup 1, COVID-19 pandemisi öncesi dönem (1 Ocak 2018 - 10 Mart 2020); Grup 2, COVID-19 pandemisi sırasında sıkı önlemlerin uygulandığı dönem (11 Mart 2020 - 30 Haziran 2021); ve Grup 3, COVID-19 pandemisi önlemlerinin kaldırıldığı dönem (1 Temmuz 2021 - 30 Haziran 2023). \u0000Bulgular: Tüm popülasyonda GAS prevalansı %23.2 (n=3024) idi. Gruplar arasında, Grup 3 en yüksek GAS sıklığına sahipken, bunu Grup 1 ve ardından Grup 2 izledi (Grup 1: %18.1, Grup 2: %6.0, Grup 3: %29.6, p < 0.001). COVID-19 pandemisine karşı katı önlemlerin alındığı dönemde, COVID-19 öncesi döneme kıyasla GAS sıklığında önemli bir azalma gözlemlendi. Ancak, COVID-19 ile ilişkili kısıtlamaların gevşetilmesiyle, özellikle 2022'nin son çeyreği ve 2023 ilkbaharında, GAS sıklığında belirgin bir artış saptandı. \u0000Sonuçlar: Çocuklarda, GAS sıklığı COVID-19 izolasyon önlemleriyle önemli ölçüde azaldı. Ancak, bu izolasyon önlemlerinin gevşetilmesinin ardından ani bir artış gözlemlendi.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":" 563","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of Scoring Systems in Non-Biliary Acute Pancreatitis Prognosis: A Comparative Analysis of Ranson and Balthazar Scores","authors":"N. Aladağ, Müjgan Tuna, Seydahmet Akin","doi":"10.18663/tjcl.1450667","DOIUrl":"https://doi.org/10.18663/tjcl.1450667","url":null,"abstract":"Aim: The Ranson score (RS) and the Balthazar Computed Tomography Severity Index (CTSI) are commonly used to predict the severity and prognosis of acute pancreatitis (AP). However, the diagnostic superiority of these scoring systems in predicting the prognosis of non-biliary AP remains unclear. Therefore, this study aimed to compare the RS and CTSI in predicting the prognosis of non-biliary AP. \u0000Material and Methods: This retrospective study included 67 non-biliary AP patients who were followed at the Internal Medicine clinic of Hospital, between January 2021 and May 2023. The RS and CTSI were calculated based on the laboratory and radiological findings of the patients. The endpoints consisted of prolonged hospitalization (≥8 days), complications, and mortality. \u0000Results: The mean age of the patients was 50.1±8.3 years, and the majority were male (59.7%). Complications developed in 11.9% of the patients, prolonged hospitalization occurred in 26.9%, and death occurred in 6%. In predicting the risk of prolonged hospitalization and complications, CTSI exhibited superior diagnostic performance compared to RS (the area under the curve (AUC) = 0.590 vs. 0.856, p","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":" 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140221154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Syphilis Screening Results in Donors Applying to a Transfusion Center of a Tertiary Hospital","authors":"Y. Çekli","doi":"10.18663/tjcl.1445369","DOIUrl":"https://doi.org/10.18663/tjcl.1445369","url":null,"abstract":"Aim: In blood banking, the significance of diagnosing syphilis, a condition caused by Treponema pallidum, cannot be overstated. It necessitates the adoption of the most appropriate algorithm for catching possible cases among donors, thereby minimizing donor loss. The World Health Organization in 2003, and the European Centre for Disease Prevention and Control in 2010, advised starting syphilis screenings with Treponemal tests. This study aimed to investigate the outcomes of confirmatory tests conducted on blood donor candidates with reactive Enzyme-Linked Immunosorbent Assay (ELISA) test results in syphilis screening. \u0000Material and Methods: In this retrospective study, 69,127 donors who applied as blood donors to the blood bank of a Training and Research Hospital between 2014 and 2021 were examined. Specimens from donor candidates who tested reactive in the syphilis screening test were dispatched to the Microbiology Reference Laboratory of the Turkey Public Health Institution for verification tests. The Fluorescent Treponemal Antibody Absorption (FTA-ABS) or Treponema Pallidum Hemagglutination Assay (TPHA) tests were utilized as the verification tests. \u0000Results: Reactive test results were obtained repeatedly in 128 donors (0.18%). As a confirmatory test, TPHA was administered to 32 donors, resulting in 11 positive outcomes (34.3%) (False positivity ratio = 65.7%). FTA-ABS was performed as a verification test on 96 donors, with 59 (61.4%) testing positive (False positivity ratio = 38.6%). Out of 48 donors with an ELISA signal-to-cutoff ratio above five, the FTA-ABS test was conducted on 42, yielding 41 positive and one negative result. \u0000Conclusion: The study suggests that using FTA-ABS as a confirmatory test for ELISA-reactive donors improves syphilis detection accuracy.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"16 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140230585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Akalazya Hastalarında Peroral Endoskopik Miyotominin Etkinliği ve Güvenliği","authors":"Nermin MUTLU BİLGİÇ, Zuhal Çalişkan, Oğuzhan Öztürk, Mehmet Ali Saruhan, Kamil Ozdi̇l","doi":"10.18663/tjcl.1443948","DOIUrl":"https://doi.org/10.18663/tjcl.1443948","url":null,"abstract":"Amaç: Bu çalışma, akalazya tanısı almış yetişkin hastalarda POEM prosedürünün etkinlik ve komplikasyonlar açısından sonuçlarını sunmayı ve yaş, cinsiyet ve obezite gibi geleneksel risk faktörlerinin bu sonuçlar üzerindeki potansiyel etkilerini araştırmayı amaçlamaktadır. \u0000Gereç ve Yöntemler: Ocak 2021'den Temmuz 2023'e kadar POEM prosedürü geçiren toplam 51 hasta geriye dönük olarak değerlendirildi. Ana sonlanım noktası, prosedürden iki ay sonra Eckardt skorunun 3 veya daha düşük olmasıyla belirlenen klinik başarı oranı olarak değerlendirildi. İkincil sonlanım noktaları, herhangi bir advers olay, yoğun bakım ünitesine kabul ve prosedür sonrası iki ayda reflü semptomlarının varlığı olarak değerlendirildi \u0000Bulgular: Hastaların ortalama yaşı 49,3 ± 13,3 yıl idi ve semptomların süresi 6 ay ile 10 yıl arasında değişiyordu. Ameliyat öncesi medyan Eckardt skorları 9 idi ve 5 ile 12 arasında değişiyordu. Prosedür sonrası 2. ayda hastaların %96,1'i 3 veya daha düşük bir Eckardt skoruna sahipti, medyan 8 puanlık bir azalma ile (IQR = 6 – 8, p < 0.001). Hastaların %13,7'si advers olaylarla karşılaştı, bunların %3,9'u pnömomediastinum, %1,9'u mediastinit ve %1,9'u tünel içi kanama içeriyordu. Prosedür sonrası 2. ayda hastaların %17,6'sı reflü özofajiti sergiledi. Hiçbir hastada mortalite gözlenmedi. \u0000Sonuçlar: POEM, akalazya için etkili, güvenli ve minimal invaziv bir tedavi olup, semptomatik rahatlama, yaşam kalitesinde iyileşme sunan ve yüksek klinik başarı oranı ile umut verici bir terapötik seçenek olarak öne çıkmaktadır. Düşük oranda gözlenen advers olaylar yönetilebilir düzeydeydi ve mortaliteye neden olmadı.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"223 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Açık kalp ameliyatı geçiren ileri yaştaki hastalarda akut böbrek hasarı için risk faktörleri","authors":"Deniz Sarp Beyazpinar, M. Erol","doi":"10.18663/tjcl.1441211","DOIUrl":"https://doi.org/10.18663/tjcl.1441211","url":null,"abstract":"Abstract: \u0000Objective: Our studys goal is, to determine the risk factors for acute kidney injury in octogenarians undergoing open-heart surgery to decrease mortality and morbidity by enhancing accurate patient selection in the preoperative period. \u0000Materials and Method: Between January 2017-December 2022, 678 patients analyzed retrospectively. The patient groups were divided as follows: < 70 years old = control group, 70–80 years old = septuagenarian group, and > 80 years old = octogenarian group. Age, sex, ethnicity, Euroscore, preoperative serum creatinine levels, postoperative first-month serum creatinine levels, dialysis requirements, and first-year mortality parameters were analyzed. \u0000Results: 206 patients has included into study, with 94 patients in the control group (79 male), 29 patients in the septuagenarian group (22 male), and 83 patients in the octogenarian group (70 male). There was a statistically significant difference between the groups based on preoperative serum creatinine. Of the 26 patients requiring renal replacement therapy, 6 were in the control group, 3 were in the septuagenarian group, and 17 were in the octogenarian group. There was a statistically significant difference between groups based on requiring renal replacement therapy, and 11 of the patients requiring renal replacement therapy died. Of the 22 patients who died overall, 4 were in the control group, 3 were in the septuagenarian group, and 15 were in the octogenarian group. \u0000Conclusion: In the senior patient group, the best approach for optimal patient selection is to ensure meticulous surgical technique and myocardial protection.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"8 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140239244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Preoperative Nutritional status with Postoperative Mortality and Morbidity In Congenital Heart Patients","authors":"Mustafa Yılmaz","doi":"10.18663/tjcl.1441973","DOIUrl":"https://doi.org/10.18663/tjcl.1441973","url":null,"abstract":"Aim: This study aimed to determine the relationship between preoperative nutritional status and postoperative mortality and morbidity in pediatric patients undergoing congenital heart surgery. \u0000Material and Methods: The study enrolled 36 pediatric patients, aged between 3 and 60 months, who were hospitalized for congenital heart surgery. Nutritional status assessment involved measuring the triceps skinfold thickness (TSFT) prior to surgery. The investigation focused on establishing associations between the provided preoperative data and various postoperative outcomes, including duration of Intensive Care Unit (ICU) stay, mechanical ventilator requirements, inotrope usage, and 30-day mortality.” \u0000Results: In the preoperative period, 8.3% of the patients were below 0.05). \u0000Conclusion: No significant correlation was found between preoperative nutritional status and postoperative morbidity and mortality in pediatric patients.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"32 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140249089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid-19 Sürecinde Gebelerin Anksiyete, Durumluk ve Sürekli Kaygı Düzeylerinin Belirlenmesi","authors":"Hatice Kinaci, Suzan Onur","doi":"10.18663/tjcl.1406568","DOIUrl":"https://doi.org/10.18663/tjcl.1406568","url":null,"abstract":"Öz \u0000Amaç: Gebelik dönemi, kadınlarda ruh sağlığı rahatsızlıklarının gelişmesi ve var olan hastalıkların artış göstermesinde risk faktörü olarak görülmektedir. COVID-19 salgın sürecinde özellikle gebe kadınların ruhsal yönden daha çok etkilenebilecekleri düşünüldüğünden; bu süreçte gerçekleştirilen çalışma, gebe kadınların gebelik süresince algılanan anksiyete ve kaygı düzeylerinin belirlenmesi ve buna uygun önerilerin geliştirilmesi amacıyla yapılmıştır. \u0000Gereç ve Yöntemler: Gerekli etik kurul ve kurum izinleri alındıktan sonra başlanan tanımlayıcı tipteki bu çalışmaya, Ankara Eğitim ve Araştırma Hastanesi Kadın Doğum Polikliniğine başvuran yalnızca gebelik tanılı 402 gebe dahil edildi. İstatistiksel analizler için SPSS 20.0 paket programı; veri toplama araçları olarak kişisel bilgi formu, BECK Anksiyete Ölçeği, Durumluk Kaygı Ölçeği ve Sürekli Kaygı Ölçeği kullanıldı. BECK Anksiyete Ölçeğinden alınan toplam puan bireyin yaşadığı anksiyetenin şiddetini göstermektedir. 0-7 puan minimal düzeyde, 8-15 puan hafif düzeyde, 16-25 puan orta düzeyde ve 26-63 puan şiddetli düzeyde anksiyeteye sahip olarak kabul edildi. Durumluk Kaygı Ölçeği ve Sürekli Kaygı Ölçeği ortalama puanları için; 0-19 puan ‘Anksiyete yok’, 20-39 puan ‘Hafif Anksiyete’, 40-59 puan ‘Orta Düzeyde Anksiyete’, 60-79 puan ‘Ağır Düzeyde Anksiyete’, 80 ve üstü puan ise ‘Panik’ olarak değerlendirildi. \u0000Bulgular: Katılımcıların yaş ortalamasının 26,04±4,84, BECK Anksiyete Ölçeği puan ortalamasının 16,94±11,22, Durumluk Kaygı Ölçeği puan ortalamasının 41,83±16,23, Sürekli Kaygı Ölçeği puan ortalamasının ise 44,20±13,07 olduğu tespit edilmiştir. Gebelerin BECK Anksiyete Ölçeği puanlarına göre; %28,4’ünün hafif düzeyde, %24,9’unun orta düzeyde, %24,1’inin şiddetli düzeyde anksiyetesinin olduğu ve %22,6’sının ise anksiyetesinin olmadığı belirlenmiştir. \u0000Sonuç: Bu çalışma, COVID-19 sürecinin, gebelik döneminde görülen anksiyete ve kaygı düzeyi üzerine anlamlı bir etkisinin olmadığını göstermiştir ve COVID-19 sürecinde gebe olan kadınların kaygı düzeylerinde anlamlı bir fark bulunmamıştır. \u0000Kaynaklar: \u00001. Yang, H., Wang, C., Poon, LC. Novel Corona virus infection and pregnancy. Ultrasound Obstet Gynecol. 2020; 55(4):435-37. \u00002. Liang, H., Acharya, G. Novel coronavirus disease (COVID-19) in pregnancy: What clinical recommendations to follow. ActaObstetGynecolScand. 2020; 99(4), 439-42. \u00003. Royal College of Obstetricians and Gynaecologists. Coronavirus infection and pregnancy [Internet]. 2020. [cited 2020 May 02]. Available from: https://www.rcog.org.uk/en/guidelines-researchservices/guidelines/coronaviruspregnancy/covid-19-virus-infection-and-pregnancy/. \u00004. Woody, C., A., Ferrari, A., Siskind, et al. A systematic review and meta-regression of the prevalence and incidence of perinatal depression. 2017; 219,86-92. doi:10.1016/j.jad.2017.05.003. \u00005. Bussières, E.-L., Tarabulsy, G. M., Pearson, J., Tessier, R., Forest, J.-C., Giguère, Y. Maternal prenatal stress and infant birth weigh tand gestationa","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"54 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140394474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesia Management in transvaginal ultrasound guided oocyte retrieval procedure: A mini review","authors":"Selin Erel, Beyza Mehri BÜYÜKGEBİZ YEŞİL, B. Günaydın","doi":"10.18663/tjcl.1446951","DOIUrl":"https://doi.org/10.18663/tjcl.1446951","url":null,"abstract":"Anesthesia/analgesia management in oocyte retrieval procedures plays a pivotal role in ensuring patient comfort, safety, and procedural success in in vitro fertilization treatment. This mini review addresses pre-/periprocedural considerations, choice of anesthesia techniques and anesthetic drugs to provide adequate pain relief and comfort tailored to individual patient needs, through conscious sedation, regional anesthesia, or general anesthesia in patients scheduled for transvaginal ultrasound guided oocyte retrieval. Clinicians must consider patient comorbidities, medication history, and procedural requirements when selecting anesthesia techniques.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"34 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140262000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenotonsillektomi ve Tonsillektomi operasyonlarında preemptif analjezinin derlenme deliryumu üzerine etkisi","authors":"Bilge OLGUN KELES, Elvan TEKİR YILMAZ","doi":"10.18663/tjcl.1414090","DOIUrl":"https://doi.org/10.18663/tjcl.1414090","url":null,"abstract":"ABSTRACT \u0000Objective: Emergency delirium is a phenomenon of unknown etiology, mostly seen in young children, characterised by aggressive behaviour, lack of eye contact and lack of awareness of the environment. It has been shown to have many causes, but head and neck surgery, inhaled agents and post-operative pain are the most common. The PAED scale is the most sensitive scale and a score of 10 or more indicates immediate delirium. \u0000Pre-emptive analgesia is the interruption of pain pathways before the painful stimulus occurs, and its effectiveness in post-operative analgesia has been confirmed by many studies. This study was designed with the hypothesis that post-operative pain reduced by pre-emptive analgesia would reduce emergency delirium. \u0000Materials and methods: After ethics committee approval, 96 ASAI-II patients aged 2-7 years undergoing adenotonsillectomy and tonsillectomy were randomised into two groups. Analgesics were administered to the pre-emptive group before induction and to the intra-operative group 15 min after the start of surgery. In the recovery room, ED was assessed using the PAED scale and pain scores were assessed using the FLACC scores. PAED>10 was considered recovery delirium. The primary outcome was the incidence of recovery delirium. Secondary outcomes were delirium and pain scores. \u0000Results: PAED and FLACC scores were significantly lower in the preemptive group. There was a significant difference in the incidence of ED between the two groups only at 5 minutes. \u0000Conclusions: In children undergoing adenotonsillectomy and tonsillectomy, preemptive analgesia reduced postoperative pain scores and delirium scores, but did not reduce the incidence of recovery delirium.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"107 S120","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140429252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tekrarlayan İdrar Yolu Enfeksiyonlarında Etyolojik Modeller ve Antibiyotik Direnci","authors":"İlyas Yağmur","doi":"10.18663/tjcl.1401979","DOIUrl":"https://doi.org/10.18663/tjcl.1401979","url":null,"abstract":"Abstract: \u0000Aim: Recurrent urinary tract infections (rUTIs) pose a significant clinical challenge due to their high prevalence and the escalating issue of antibiotic resistance. Understanding the etiological patterns and risk factors associated with rUTIs is crucial for effective management and prevention strategies. Escherichia coli is a prevalent pathogen in UTIs, but its emerging antibiotic resistance is a growing concern. This study aims to retrospectively analyze the prevalence of E. coli and patterns of antibiotic resistance in rUTIs. \u0000Material and Methods: Conducted at Özel Kızılay Kağıthane Hospital between 2020 and 2023, this retrospective cohort study included 265 patients diagnosed with rUTIs. Data encompassed demographics, clinical history, uropathogens, and antibiotic resistance patterns, offering insights into the etiology and resistance trends in this population. \u0000Results: Escherichia coli emerged as the main uropathogen in 70.6% of rUTI cases, with a significant proportion showing resistance to cotrimoxazole (54.5%) and fluoroquinolones (46.5%). The study predominantly involved female patients (79.2%), with sexual activity noted as a notable risk factor in 60% of these cases. Additionally, 40% of patients experienced moderate to severe symptoms, impacting their quality of life. \u0000Conclusion: This study highlights the urgent need to address the challenge of rUTIs, especially given the rising rates of antibiotic resistance, particularly in Escherichia coli isolates. It emphasizes the importance of considering patient demographics and risk factors in managing rUTIs. Future research, including prospective studies, is essential for developing effective therapeutic and preventive strategies to mitigate the burden of rUTIs on individuals and healthcare systems.","PeriodicalId":510540,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"16 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140430049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}