European Journal of Oncology Nursing最新文献

{"title":"Examining the impact of cancer treatment on personhood: A participatory research investigation into the unique experiences of lesbian, gay, and bisexual individuals","authors":"Gareth Hill ,&nbsp;Cathy Bulley","doi":"10.1016/j.ejon.2024.102738","DOIUrl":"10.1016/j.ejon.2024.102738","url":null,"abstract":"<div><h3>Purpose</h3><div>Cancer incidence is growing in the UK population and will affect half of all individuals in their lifetime, with most new diagnoses occurring over the age of 60 years old. Despite legal reforms and liberation of lesbian, gay, bisexual, transgender, queer, or questioning (LGBTQ) people's rights in recent years, many LGBTQ people affected by cancer will have faced significant societal discrimination in their lives. The aim of this research was to explore how cancer treatment impacts on the personhood of LGB people, and to increase understanding of social issues specific to this community.</div></div><div><h3>Methods</h3><div>Underpinned by person-centred principles and Critical Social Theory, a community-based participatory inquiry was carried out with nine LBG people who had been affected by cancer. In two subsequent sessions, participants created an identity map and then reflected on how cancer and care experiences had impacted their identity. Initially, content analysis of transcripts was informed by Mezirow's perspective transformation, followed by inductive thematic analysis within each data framework category. Participants were invited to provide feedback on the identified themes.</div></div><div><h3>Results</h3><div>The processes of coming out and facing a cancer diagnosis emerged as significant crises, leading to personal transformation. Factors such as past experiences of homophobia, duration of being openly out, and confidence in embracing altered identities influence interactions with healthcare providers and the level of support received.</div></div><div><h3>Conclusions</h3><div>This research makes a unique contribution by shedding light on the unreported support needs of LGB individuals affected by cancer, suggesting the need for additional assistance.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102738"},"PeriodicalIF":2.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception and coping with self-perceived burden among colorectal cancer patients and their caregivers: A qualitative study","authors":"Xuan Chen ,&nbsp;Junrui Zhou ,&nbsp;Zhiming Wang ,&nbsp;Chunyan Lin ,&nbsp;Jie Zhao ,&nbsp;Qiuping Li","doi":"10.1016/j.ejon.2024.102732","DOIUrl":"10.1016/j.ejon.2024.102732","url":null,"abstract":"<div><h3>Purpose</h3><div>Self-perceived burden can take a toll on the physical and psychological well-being of cancer couples and prevent them from achieving favorable outcomes. There is limited qualitative research synthesizing the cognition and coping with self-perceived burden among Chinese colorectal cancer patients and their caregivers. Therefore, this study examined perceptions of self-perceived burden and coping strategies from the perspectives of colorectal cancer patients, their spousal caregivers and nursing staff.</div></div><div><h3>Methods</h3><div>A qualitative study based on semi-structured interviews was implemented from May 15 to July 14, 2023. Data were analyzed using inductive thematic analysis.</div></div><div><h3>Results</h3><div>This study summarized the cognition and coping strategies regarding self-perceived burden through three themes. Life under self-perceived burden contained sub-themes of Uncomfortable role changing, The handling of interpersonal relationships and Communication attitudes. What need to cope with contained sub-themes of Physical changes and discomfort, Negative emotions, Inappropriate decision-making and Negative communication. Coping with different perspectives contained sub-themes of Improving self-care ability correctly, Maintaining emotional stability, Finding new meaning and Solid family support.</div></div><div><h3>Conclusions</h3><div>The presence of self-perceived burden hinders good outcomes for colorectal cancer couples. It is necessary to help colorectal cancer couples cope with self-perceived burden together. Nursing staff need to be a bridge of communication and exchange for colorectal cancer couples, providing them with effective and reliable information and support, thus helping colorectal cancer patients and their spousal caregivers achieve true inner peace and better outcomes.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102732"},"PeriodicalIF":2.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142744245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticipatory grief - A neglected phenomenon among relatives of patients with incurable cancer: A qualitative study","authors":"Bethina Thulstrup Paulsen ,&nbsp;Mathilde Laura Kærgaard Johansen ,&nbsp;Sarah Kjærsgaard Lund ,&nbsp;Helle Enggaard ,&nbsp;Lone Jørgensen","doi":"10.1016/j.ejon.2024.102730","DOIUrl":"10.1016/j.ejon.2024.102730","url":null,"abstract":"<div><h3>Purpose</h3><div>To explore the experience of being a relative to a patient with incurable cancer and the relatives’ perceived need for support.</div></div><div><h3>Method</h3><div>A qualitative design with a critical hermeneutics approach was applied. In total, 15 semi-structured individual interviews with relatives of patients with incurable cancer were conducted and analysed through a Paul Ricœur-inspired analysis.</div></div><div><h3>Findings</h3><div>Three themes emerged: <em>(1) being in a paradoxical waiting position, (2) the complex need for a respite during the illness</em> and <em>(3) the importance of person-centred information and continuity.</em> The themes highlight how relatives are in a vulnerable position experiencing anticipatory grief while waiting for the patient's death. They have ambivalent feelings because of the tension between the need to be supportive and the need for a respite from the illness. However, they do not want to centre their needs and remove the attention from the patient. Their needs change over time and increase the longer the cancer has lasted. In addition, the relatives need person-centred information and continuity among healthcare professionals.</div></div><div><h3>Conclusion</h3><div>Relatives of patients with incurable cancer are in a vulnerable position, with a range of complex and varied needs for support. This underscores the importance of healthcare professionals being aware of anticipatory grief and the management of relatives’ needs to avoid complicated grief and its consequences.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102730"},"PeriodicalIF":2.7,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between sexuality, body image and health-related quality of life in patients treated for diffuse large B-cell lymphoma: A cross-sectional study","authors":"Cecilia Olsson ,&nbsp;Maria Larsson ,&nbsp;Anna Josse Eklund ,&nbsp;Anders Ringnér","doi":"10.1016/j.ejon.2024.102729","DOIUrl":"10.1016/j.ejon.2024.102729","url":null,"abstract":"<div><h3>Purpose</h3><div>Sexuality and body image are closely related to health-related quality of life (HRQoL), but these factors are less investigated in patients treated for lymphoma.</div><div>Therefore, the aim of this study was to describe and explore the associations between sexuality, body image, comorbidities and HRQoL in patients treated for diffuse large B-cell lymphoma.</div></div><div><h3>Methods</h3><div>A cross-sectional study with 257 patients (25% response rate) was conducted in 2019 using measures for sexuality, HRQoL and body image and data from the Swedish National Quality Registry for Leukemia–Subregistry for Lymphoma.</div></div><div><h3>Results</h3><div>The participants had a mean HRQoL of 69.75 on a 1 to 100 scale, and the functional scales ranged from 68.50 for Role to 80.82 for Social functioning. The symptoms ranged from 5.56 for nausea and vomiting to 37.73 for fatigue. Regarding body image, the participants scored a total of 14.47 (reference values 10–40). The total score for Sexual adjustment was 3.02 (fair), and for the subscales Sexual Interest 2.63 (low), Sexual Relation 2.72 (low), Sexual Function 3.62 (high) and Sexual Satisfaction 3.50 (high). HRQoL was positively associated with Sexual Relation; however, negative body image and comorbidities showed negative associations. The model explains 39.6% of the variation in HRQoL.</div></div><div><h3>Conclusion</h3><div>The positive impact of sexual relationships on HRQoL was highlighted, which emphasised the unfavourable effect of negative body image and comorbidities on HRQoL for lymphoma patients. Cancer nurses should address these topics with patients to improve their long-term well-being.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"73 ","pages":"Article 102729"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological and biological stress pathways as common mechanisms underlying a psycho-neurological symptom cluster in cancer patients: Perceived stress, cortisol, and ACTH","authors":"Hee-Ju Kim ,&nbsp;Kyung Mi Chae ,&nbsp;Sun-Ok Jung ,&nbsp;Su Wol Chung ,&nbsp;Tenko Raykov","doi":"10.1016/j.ejon.2024.102728","DOIUrl":"10.1016/j.ejon.2024.102728","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to examine (a) whether psychological stress is associated with experiencing multiple psycho-neurological symptoms (depression, cognitive impairment, fatigue, sleep disturbance, and pain) as a cluster and (b) whether stress hormones (adrenocorticotropic hormone [ACTH] and cortisol) are associated with psychological stress and symptom cluster experience.</div></div><div><h3>Methods</h3><div>This cross-sectional study analyzed data from 133 patients with hematologic cancer awaiting chemotherapy. Enzyme-linked immunosorbent assays analyzed the morning stress hormone levels (ACTH and cortisol). Latent profile analyses identified the group experiencing a psycho-neurological symptom cluster. Factors influencing the experience of the psycho-neurological symptom cluster were included as covariates and analyzed using multinomial logistic regression.</div></div><div><h3>Results</h3><div>Thirty-three percent (n = 44) experienced all five psycho-neurological symptoms as a cluster and experienced each symptom in a higher severity than those who did not experience the symptom cluster (<em>p</em>s &lt; 0.05). Thereby, this group legitimately experienced the psycho-neurological symptom cluster. The major determinant of this group was the perceived psychological stress (OR = 8.05, 95% CI = 3.08; 20.99). Further, each symptom demonstrated a positive association with stress levels (correlation r ranged from 0.22 to 0. 56, all ps &lt; 0.05). Participants with higher stress were more likely to experience the symptom cluster. Stress hormones levels (ACTH and cortisol) were neither associated with the symptom cluster experience nor with psychological stress levels.</div></div><div><h3>Conclusions</h3><div>Psychological stress, rather than biological stress response, is involved in experiencing the psycho-neurological symptom cluster. Managing stress levels would help alleviate this symptom cluster.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102728"},"PeriodicalIF":2.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between psychological resilience, coping strategies and fear of cancer recurrence in patients with breast cancer undergoing surgery: A descriptive, cross-sectional study","authors":"Pinar Yilmaz Eker ,&nbsp;Kubra Erturhan Turk ,&nbsp;Selma Sabanciogullari","doi":"10.1016/j.ejon.2024.102719","DOIUrl":"10.1016/j.ejon.2024.102719","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aims to determine the relationship between psychological resilience, coping strategies and the fear of cancer recurrence in women who have undergone surgical procedures due to breast cancer.</div></div><div><h3>Methods</h3><div>The study was conducted using a descriptive, cross-sectional, and correlational research design. The sample of the study consisted of 252 women. Data were collected with The Patient Information Form, The Psychological Resilience Scale for Adults, The Ways of Coping Questionnaire and The Fear of Cancer Recurrence Inventory.</div></div><div><h3>Results</h3><div>The mean scores of Psychological Resilience Scale for Adults, Fear of Cancer Recurrence Inventory, and the optimistic and self-confident subscales of the Ways of Coping Questionnaire among participants were found to be above average. The mean scores of the seeking social support and submissive subscales were at a moderate level, while the mean scores of the hopelessness approach subscale were below the moderate level. A moderate positive significant relationship was found between the total mean score of the Psychological Resilience Scale for Adults and the mean scores of the optimistic approach, self-confident approach, submissive approach, and seeking social support subscales of the Ways of Coping Questionnaire.</div></div><div><h3>Conclusion</h3><div>A direct relationship was found between psychological resilience and coping strategies. However, this relationship could not be found with fear of cancer recurrence. It was concluded that the level of psychological resilience and coping strategies among breast cancer survivors can be positively influenced through the implementation of professional interventions aimed at fostering growth, addressing the initial cancer diagnosis, and promoting healthy adaptation.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"73 ","pages":"Article 102719"},"PeriodicalIF":2.7,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supporting cancer-related fatigue self-management: A conversation analytic study of nurse counsellor and cancer survivor consultations","authors":"Oluwaseyifunmi Andi Agbejule ,&nbsp;Stuart Ekberg ,&nbsp;Nicolas H. Hart ,&nbsp;Raymond J. Chan","doi":"10.1016/j.ejon.2024.102726","DOIUrl":"10.1016/j.ejon.2024.102726","url":null,"abstract":"<div><h3>Purpose</h3><div>Cancer-related fatigue (CRF) is a prevalent and distressing symptom experienced by people affected by cancer. A breakdown of the clinician-patient partnership and suboptimal clinician communication has been identified as a significant barrier to implementing into clinical practice effective self-management strategies for CRF. This study examined the use and impact of communication practices employed by trained cancer nurse counsellors when providing CRF self-management support to cancer survivors.</div></div><div><h3>Methods</h3><div>Interactions from 41 telehealth consultations between three nurse counsellors and 23 cancer survivors in a CRF self-management support clinic in Queensland, Australia were recorded and analysed using conversation analysis methods.</div></div><div><h3>Results</h3><div>Analysis found that in instances where nurses established the agenda of a consultation from the outset of a session (e.g., focusing on fatigue self-management support), cancer survivors displayed clearer understandings of their self-management role, the tasks, and goals of a session; and displayed less difficulty engaging in supportive care discussions. Furthermore, clinicians used formulation practices, such as summarising dialogue, to sustain focus on fatigue during consultations, and to close discussion matters not ostensibly pertinent to fatigue self-management planning supporting the goals of the CRF SMS clinic consultations.</div></div><div><h3>Conclusion</h3><div>For supportive care sessions targeting fatigue management, clinicians should ideally focus discussion on CRF support early, by clearly introducing the agenda at the outset of the consultation while also asking for client agreement. Periodically summarising patient's talk allows clinicians to maintain a focus on matters relevant for self-management fatigue planning and provide support within the typically constrained timeframes allocated for addressing CRF.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"73 ","pages":"Article 102726"},"PeriodicalIF":2.7,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expectations for gynaecological cancer nursing guidance development: A qualitative exploration: Part 1 – Creating foundational support","authors":"Natalie Williams ,&nbsp;Georgia Halkett ,&nbsp;Tracey Moroney ,&nbsp;Sharon MacLean ,&nbsp;Olivia Cook","doi":"10.1016/j.ejon.2024.102727","DOIUrl":"10.1016/j.ejon.2024.102727","url":null,"abstract":"<div><h3>Purpose</h3><div>Nurses are acknowledged as essential in the delivery of best practice gynaecological cancer care however previous studies have identified challenges in these nursing roles. Recommendations include the development of nursing guidance focused on supporting people with a gynaecological cancer. This study aimed to explore perceptions and expectations for the development of a gynaecological cancer nursing guidance resource in Australia and investigate preferred design and content inclusion. This paper presents the findings on expectations for the resource purpose.</div></div><div><h3>Methods</h3><div>Utilising an exploratory qualitative descriptive design, 20 nurses and seven people with lived experience of gynaecological cancer participated in focus groups or interviews following a semi-structured interview guide. Transcripts underwent inductive content analysis.</div></div><div><h3>Results</h3><div>All 27 participants identified as female, lived in one of 5 Australian states, included representation from regional locations (n=9, 33%), and mostly identified as Australian or mixed Australian ethnicity (n=25, 93%). The major theme, “Foundational support resource for nurses”, described how participants require a resource to support the delivery of gynaecological cancer nursing care. Participants articulated their goals for the resource through four subthemes: reducing variation in care; acknowledging diversity in nursing roles; addressing barriers; supporting development.</div></div><div><h3>Conclusion</h3><div>The development of a guidance resource for gynaecological cancer nursing is supported by Australian gynaecological cancer nurses and people with cancer lived experience. It is expected its implementation will assist to improve cancer outcomes, equitable access to quality care and support the development and sustainability of the gynaecological cancer nursing workforce.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"73 ","pages":"Article 102727"},"PeriodicalIF":2.7,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between changes in nutritional status during treatment and overall survival of newly diagnosed nasopharyngeal carcinoma patients","authors":"Wen-Pei Chang","doi":"10.1016/j.ejon.2024.102721","DOIUrl":"10.1016/j.ejon.2024.102721","url":null,"abstract":"<div><h3>Purpose</h3><div>This study investigates the relationship between changes in nutritional status during treatment and overall survival in NPC patients.</div></div><div><h3>Method</h3><div>Using a prospective cohort design, the electronic health records of newly diagnosed NPC patients from a medical center in Taiwan (from January 1, 2018, to March 31, 2024) were analyzed. A total of 73 newly diagnosed NPC patients were tracked; nutritional indicators such as body mass index (BMI), prealbumin levels, and Patient-Generated Subjective Global Assessment (PG-SGA) scores were recorded at four time points: one week before treatment, the first week of treatment, and four and eight weeks after treatment began.</div></div><div><h3>Results</h3><div>The study found that most patients experienced a decrease in BMI (B = −0.62, <em>p</em> &lt; .001) and prealbumin levels (B = −0.79, <em>p</em> = .015) during treatment, although BMI remained in the overweight range and prealbumin stayed within normal levels. PG-SGA scores increased (B = 1.01, <em>p</em> &lt; .001), indicating a shift from low to moderate nutritional risk. Univariate Cox regression analysis showed that the Charlson Comorbidity Index (HR = 1.86, 95% CI: 1.38–2.51), NPC stage (HR = 15.67, 95% CI: 2.07–118.61), treatment method (HR = 2.96, 95% CI: 1.45–6.04), prealbumin (HR = 2.95, 95% CI: 1.46–5.99), and PG-SGA score trajectories (HR = 2.85, 95% CI: 1.27–6.40) were associated with overall survival. However, multivariate analysis revealed that the survival of NPC patients was only associated with CCI and NPC stage.</div></div><div><h3>Conclusions</h3><div>The study underscores the importance of monitoring nutritional status changes during treatment, particularly prealbumin and PG-SGA trajectories.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"73 ","pages":"Article 102721"},"PeriodicalIF":2.7,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of frailty on chemotherapy intolerance in patients with cervical cancer: A longitudinal study","authors":"Yanhong Wang ,&nbsp;Yaya Zhang ,&nbsp;Xueping Liang ,&nbsp;Jin Liu ,&nbsp;Yanan Zhao ,&nbsp;Qingling Su","doi":"10.1016/j.ejon.2024.102725","DOIUrl":"10.1016/j.ejon.2024.102725","url":null,"abstract":"<div><h3>Purpose</h3><div>To explore the potential effects of frailty on chemotherapy intolerance in patients with cervical cancer.</div></div><div><h3>Methods</h3><div>A longitudinal study of patients with cervical cancer undergoing postoperative Adjuvant Chemotherapy (ACT) was conducted at a hospital in Northwest China from July 2020 to December 2021. Baseline frailty was assessed using the Tilburg Frailty Indicator. Chemotherapy intolerance was obtained from electronic medical records during the intervals between each postoperative chemotherapy session. We used Generalized Estimating Equations (GEE) to determine the predictors and cox regression analysis to analyze the impact of frailty on chemotherapy intolerance.</div></div><div><h3>Results</h3><div>A total of 259 patients with postoperative cervical cancer with a mean age of 52.5 years (SD = 10.3) participated in this study. The incidence of chemotherapy intolerance in the frail group at T1, T2, T3 and T4 was 51.6%, 38.9%, 55.6% and 73.7%, respectively. The patients with frailty were more likely to have chemotherapy intolerance (OR = 1.495, 95% CI: 1.074–2.080, <em>P</em> &lt; 0.05), prolonged hospitalizations (OR = 1.577, 95% CI: 1.086–2.291, <em>P</em> &lt; 0.05) and unplanned readmissions (OR = 2.304, 95% CI: 1.387–3.829, <em>P</em> &lt; 0.05) compared to the patients without frailty. Cox regression analysis showed that frailty increased the risk of chemotherapy intolerance by 1.681-fold (HR = 1.681, 95%CI 1.041–2.713; <em>P</em> &lt; 0.05) and unplanned readmissions by 2.812-fold (HR = 2.812, 95%CI 1.521–5.200; <em>P</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>Frailty can lead to an increased risk of chemotherapy intolerance in patients with cervical cancer undergoing postoperative ACT, and patients with frailty are more likely to experience prolonged hospitalizations and unplanned readmissions.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102725"},"PeriodicalIF":2.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}