Dm Disease-A-MonthPub Date : 2024-05-01DOI: 10.1016/j.disamonth.2024.101711
Lisa Thompson MD , Thomas Patrianakos DO , James Garcia MD , Arshia Wadhwa MD , Ellen Yang MD , Catherine Thomas MD , Robin Schneider DO , Hudson Stern MD , Camille Palma MD , Kyle Hill , Viviana Barquet MD , Susan Anderson-Nelson MD , Kenneth McMahon , Umangi Patel MD , Quraish Ghadiali MD , Dagmara Danek DO , Brian Larsen MD , Anthony Wong MD , Sherif Dawood MD , Maxine Ludington , Michael Giovingo MD
{"title":"Autoimmune Disorders and the Eye","authors":"Lisa Thompson MD , Thomas Patrianakos DO , James Garcia MD , Arshia Wadhwa MD , Ellen Yang MD , Catherine Thomas MD , Robin Schneider DO , Hudson Stern MD , Camille Palma MD , Kyle Hill , Viviana Barquet MD , Susan Anderson-Nelson MD , Kenneth McMahon , Umangi Patel MD , Quraish Ghadiali MD , Dagmara Danek DO , Brian Larsen MD , Anthony Wong MD , Sherif Dawood MD , Maxine Ludington , Michael Giovingo MD","doi":"10.1016/j.disamonth.2024.101711","DOIUrl":"10.1016/j.disamonth.2024.101711","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-05-01DOI: 10.1016/S0011-5029(24)00071-3
{"title":"Information for Readers","authors":"","doi":"10.1016/S0011-5029(24)00071-3","DOIUrl":"https://doi.org/10.1016/S0011-5029(24)00071-3","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140914313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-04-01DOI: 10.1016/j.disamonth.2024.101687
Zi-Yi Choo BS , Stephanie L. Mehlis MD , Joel C. Joyce MD
{"title":"Updates in atopic dermatitis for the primary care physician: A review of advances in the understanding and treatment of atopic dermatitis","authors":"Zi-Yi Choo BS , Stephanie L. Mehlis MD , Joel C. Joyce MD","doi":"10.1016/j.disamonth.2024.101687","DOIUrl":"10.1016/j.disamonth.2024.101687","url":null,"abstract":"<div><p><span><span><span><span>Atopic dermatitis (AD) is a common inflammatory skin condition occurring in both </span>pediatric<span><span> and adult patients. Pruritus is a clinical hallmark of the disease, and patients with AD often experience disruptions to their quality of life. The pathogenesis of AD is a complex and multifactorial interplay between </span>genetic factors, epidermal barrier disruption, and </span></span>immune dysregulation<span>. Clinically, AD is characterized by pruritus, eczematous skin changes, and age-specific lesion distribution patterns. Infants and </span></span>young children<span><span><span> tend to have AD lesions on their face and extensor surfaces of their extremities while older children and adults tend to have AD lesions on flexural surfaces of their extremities. Many patients also experience a chronic and relapsing disease course. Due to the chronicity and severe pruritus, lesions often undergo secondary changes like </span>lichenification. Patients with AD can experience a number of comorbidities including other </span>atopic disease<span> (i.e. allergic rhinitis, asthma), skin infections, cardiovascular, and neuropsychiatric illnesses. Management of AD depends on the severity of the disease as well as the distribution of the disease. Traditionally, treatment of AD included the use of moisturizers / emollients, </span></span></span>topical corticosteroids<span><span><span> or topical calcineurin inhibitors, or systemic therapy with non-selective </span>immunosuppressants such as corticosteroids, </span>cyclosporine<span>, azathioprine, or similar. However, in the past decade, new biologic and small molecule drugs, both topical and systemic, have become important therapeutic options for AD patients, especially for those with moderate-to-severe disease. The development of these medications, following decades of research to better understand AD, are designed to specifically target various components of immune dysregulation and inflammation implicated in the pathogenesis of AD. Their successful development and deployment now allow for an exciting new era of treatment for individuals suffering from atopic dermatitis.</span></span></p></div>","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139556796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-04-01DOI: 10.1016/j.disamonth.2024.101676
Jerrold B Leikin MD (Senior EditorDisease-A-Month)
{"title":"Foreword: Updates in atopic dermatitis for the primary care physician: A review of advances in the understanding and treatment of atopic dermatitis","authors":"Jerrold B Leikin MD (Senior EditorDisease-A-Month)","doi":"10.1016/j.disamonth.2024.101676","DOIUrl":"10.1016/j.disamonth.2024.101676","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139556791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-04-01DOI: 10.1016/S0011-5029(24)00056-7
{"title":"Information for Readers","authors":"","doi":"10.1016/S0011-5029(24)00056-7","DOIUrl":"https://doi.org/10.1016/S0011-5029(24)00056-7","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140619129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dm Disease-A-MonthPub Date : 2024-03-01DOI: 10.1016/j.disamonth.2023.101630
Jerrold B. Leikin MD (Senior EditorDisease-A-Month)
{"title":"Foreword: Health equity in pediatrics: Current concepts for the care of children in the 21st century","authors":"Jerrold B. Leikin MD (Senior EditorDisease-A-Month)","doi":"10.1016/j.disamonth.2023.101630","DOIUrl":"10.1016/j.disamonth.2023.101630","url":null,"abstract":"","PeriodicalId":51017,"journal":{"name":"Dm Disease-A-Month","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10253758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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